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  • Poster Presentations

    Access to the MSVirtual2020 ePosters.

    • Presentation Date(s):  Sept 11. 2020
    • Total Presentations: 1256

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  • PO01 - On-Demand ePosters P0001-P0286

    • Type: Poster
    • Presentations: 283
    Presented on: 9/11/2020, 08:00
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    • P0001 - A new software and analysis suite for experimental autoimmune encephalomyelitis (View Presentation)

      Keyword: Biostatistical Methods

      Cole Maguire, Blaine Caslin, Sam Bazzi, Esther Melamed, Dennis Wylie

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    • P0002 - Applying machine learning to multimodal neuroimaging data to predict visual episodic memory performance in multiple sclerosis  (View Presentation)

      Keyword: Machine Learning/Network Science

      Korhan Buyukturkoglu, Yiran Li, Ceren Tozlu, Amy Kuceyeski, James Sumowski, Victoris Leavitt

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    • P0003 - Combinatorial Genetic Interaction Analysis of Multiple Sclerosis Risk Variants (View Presentation)

      Keyword: Machine Learning/Network Science

      Corriene Sept, Farren Briggs

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    • P0004 - Convolutional neural network framework for predicting progression in early MS (View Presentation)

      Keyword: Machine Learning/Network Science

      Vinzenz Fleischer, Dumitru Ciolac, Angela Radetz, Gabriel Gonzalez-Escamilla, Julia Kroth, Julia Krämer, Sven Meuth, Sergiu Groppa, Muthuraman Muthuraman

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    • P0005 - Decoding the EDSS Scores of Multiple Sclerosis Patients from MRI Biomarkers (View Presentation)

      Keyword: Machine Learning/Network Science

      Roberto Paolella, Ezequiel De La Rosa, Vincenzo Anania, Stijn Denissen, Jeroen Van Schependom, Guy Nagels, Dominique Dive, Françoise Durand-Dubief, Dominique Sappey-Marinier, Dirk Smeets, Diana Sima

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    • P0006 - Detecting treatment response on T1 gadolinium enhancing lesion burden in clinical trials of multiple sclerosis with deep learning (View Presentation)

      Keyword: Machine Learning/Network Science

      AnithaPriya Krishnan, Zhuang Song, David Clayton, Laura Gaetano, Alex De Crespigny, Thomas Bengtsson, Richard Carano

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    • P0007 - Detecting treatment response on T2 lesion burden in multiple sclerosis clinical trials with deep learning (View Presentation)

      Keyword: Machine Learning/Network Science

      AnithaPriya Krishnan, Zhuang Song, David Clayton, Laura Gaetano, Alex De Crespigny, Thomas Bengtsson, Richard Carano

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    • P0008 - Divergent patterns of ventral attention network centrality relate to cognitive conversion in MS (View Presentation)

      Keyword: Machine Learning/Network Science

      Marijn Huiskamp, Anand Eijlers, Tommy Broeders, Iris Dekker, Bernard Uitdehaag, Frederik Barkhof, Alle Meije Wink, Jeroen Geurts, Hanneke Hulst, Menno Schoonheim

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    • P0009 - ENTIMOS: a discrete event simulation model for maximizing efficiency of infusion suites in centres treating multiple sclerosis patients (View Presentation)

      Keyword: Biostatistical Methods

      Richard Nicholas, Pamela Dobay, Kristyna Lacinova, Róisín Brennan, Marina Ziehn, Carol Lines, Nicholas Adlard

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    • P0010 - Integration of the Extreme Gradient Boosting model with clinical data to enable the early diagnosis of multiple sclerosis (View Presentation)

      Keyword: Machine Learning/Network Science

      Wei Qiu, Ruoning Wang, Wenjing Luo, Zifeng Liu, Weilong Liu, Chunxin Liu, Xun Liu, He Zhu, Rui Li, Jiafang Song, Xueqiang Hu, Sheng Han

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    • P0011 - Lesion disconnectomics using atlas-based tractography (View Presentation)

      Keyword: Machine Learning/Network Science

      Veronica Ravano, Michaela Andelova, Mario João Fartaria, Mazen Mahdi, Bénédicte Maréchal, Reto Meuli, Tomas Uher, Jan Krasensky, Manuela Vaneckova, Dana Horakova, Tobias Kober, Jonas Richiardi

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    • P0012 - Machine-learning optimized Combinatorial MRI scale (COMRISv2) correlates highly with MS disability (View Presentation)

      Keyword: Machine Learning/Network Science

      Erin Kelly, Mihael Varosanec, Alison Wichman, Mary Sandford, Peter Kosa, Bibiana Bielekova

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    • P0013 - Modeling a long-term virtual placebo arm for SPMS population in the EXPAND study: Comparing different statistical methods (View Presentation)

      Keyword: Biostatistical Methods

      Nicolas Rouyrre, Bruce A.C. Cree, Robert Fox, Patrick Vermersch, Gavin Giovannoni, Amit Bar-Or, Ralf Gold, Daniela Piani-Meier, Göril Karlsson, Ludwig Kappos

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    • P0014 - Personalized and dynamic prognostic model from the Barcelona CIS cohot (View Presentation)

      Keyword: Biostatistical Methods

      Mar Tintore, Pere Carbonell-Mirabent, Susana Otero-Romero, Alvaro Cobo Calvo, Georgina Arrambide, Jordi Río, Carmen Tur, Manuel Comabella, Carlos Nos, María Jesús Arévalo-Navinés, Luciana Midaglia, Íngrid Galán, Anka Vidal-Jordana, Joaquín Castilló, Breogán Rodríguez-Acevedo, Ana Zabalza, Marta Rodríguez, Augusto Sao-Avilés, Andrea Barros, Cristina Auger, Jaume Sastre-Garriga, Alex Rovira, Xavier Montalban

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    • P0015 - Predicted brain age as a cognitive biomarker in Multiple Sclerosis (View Presentation)

      Keyword: Machine Learning/Network Science

      Stijn Denissen, Alexander De Cock, Lars Costers, Johan Baijot, Jorne Laton, Marie D’hooghe, Miguel D'Haeseleer, Dominique Dive, Johan De Mey, Jeroen Van Schependom, Diana Sima, Guy Nagels

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    • P0016 - Progressive multifocal leukoencephalopathy lesion and brain parenchymal segmentation from MRI using serial deep convolutional neural networks (View Presentation)

      Keyword: Machine Learning/Network Science

      Omar Al-Louzi, Snehashis Roy, Ikesinachi Osuorah, Prasanna Parvathaneni, Bryan Smith, Joan Ohayon, Pascal Sati, Dzung Pham, Steven Jacobson, Avindra Nath, Daniel Reich, Irene Cortese

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    • P0017 - Translating MPRAGE to MP2RAGE improves the automatic tissue and lesion segmentation in Multiple Sclerosis patients (View Presentation)

      Keyword: Machine Learning/Network Science

      Francesco La Rosa, Thomas Yu, Germán Barquero, Jean-Philippe Thiran, Cristina Granziera, Meritxell Bach Cuadra

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    • P0018 - Variability of the response to immunotherapy among sub-groups of patients with multiple sclerosis (View Presentation)

      Keyword: Biostatistical Methods

      Ibrahima Diouf, Charles Malpas, Dana Horakova, Eva Kubala Havrdová, Francesco Patti, Vahid Shaygannejad, Serkan Ozakbas, Guillermo Izquierdo, Sara Eichau, Magd Zakaria, Marco Onofrj, Alessandra Lugaresi, Raed Alroughani, Alexandre Prat, Marc Girard, Pierre Duquette, Murat Terzi, Cavit Boz, Francois Grand'Maison, Sharif Hamdy, Patrizia Sola, Diana Ferraro, Pierre Grammond, Recai Turkoglu, Helmut Butzkueven, Bassem Yamout, Ayse Altintas, Vincent Van Pesch, Davide Maimone, Jeannette Lechner-Scott, Roberto Bergamaschi, R Karabudak, Federica Giuliano, Christopher McGuigan, Elisabetta Cartechini, Michael Barnett, Stella Hughes, Maria Sa, Ludwig Kappos, Cristina Ramo-Tello, Edgardo Cristiano, Suzanne Hodgkinson, Daniele Spitaleri, Aysun Soysal, Thor Petersen, Mark Slee, Ernest Butler, Franco Granella, Freek Verheul, Pamela McCombe, Radek Ampapa, Olga Skibina, Julie Prevost, L.G.F. Sinnige, José Luis Sánchez-Menoyo, Steve Vucic, Guy Laureys, Liesbeth Van Hijfte, Dheeraj Khurana, Richard Macdonell, Tamara Castillo-Trivino, Orla Gray, Eduardo Agüera, Ilya Kister, Cameron Shaw, Norma Deri, Talal Al-Harbi, Yara Fragoso, Tunde Csepany, Angel Sempere, Tomas Kalincik

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    • P0019 - A Comparison of Digital Gait Technologies in a Population of People with MS –When the Same Isn’t Always Exactly the Same (View Presentation)

      Keyword: Biosensors

      Olivia Kaczmarek, Jared Srinivasan, Christina Burke, Ahmed Khokhar, Myassar Zarif, Barbara Bumstead, Daniel Golan, Marijean Buhse, Edward Ofori, Mark Gudesblatt

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    • P0020 - A down-regulation of the type I interferon signaling pathway is associated with the response to teriflunomide in multiple sclerosis. (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Sunny Malhotra, Jordi Río, Juan Carlos Triviño, Anka Vidal-Jordana, Ana Zabalza, Georgina Arrambide, Breogán Rodríguez-Acevedo, Íngrid Galán, Mireia Castillo, Joaquín Castilló, Luciana Midaglia, Jaume Sastre-Garriga, Mar Tintore, Xavier Montalban, Manuel Comabella

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    • P0021 - A propensity-matched comparison of long-term disability progression in MS patients treated with dimethyl fumarate or fingolimod (View Presentation)

      Keyword: Clinical Outcome Measures

      Robert Fox, Samantha Lancia, Gary Cutter, Ruth-Ann Marrie, Jason Mendoza, James Lewin, Amber Salter

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    • P0022 - A systematic literature review and meta-analysis of the efficacy and effectiveness of PR-fampridine in patients with multiple sclerosis (View Presentation)

      Keyword: Clinical Outcome Measures

      Trond Haider, Beate Lokke, Lea Tran, Alexandra Spidalieri, Ayo Adeyemi, Carlos Acosta, Øivind Torkildsen

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    • P0023 - Alemtuzumab Real World Evidence in a Private Practice Setting (View Presentation)

      Keyword: Clinical Outcome Measures

      Duy-Tan Tran, Christopher Laganke, Lee Martin, Jim Bowen, Elizabeth Poole, Nupur Greene, Risako Robinson, Avani Patel, Joanne Chia, Lobat Hashemi

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    • P0024 - Alemtuzumab slowed brain atrophy over 6 years in patients without relapse and MRI disease activity: post hoc analysis of the pooled CARE-MS studies (View Presentation)

      Keyword: Clinical Outcome Measures

      Lauren Glendenning, Douglas L Arnold, Maria Pia Amato, Michael Barnett, Donald Barone, David Brandes, Matthew Carraro, Giancarlo Comi, Sara Eichau, Amir Mazhari, Kunio Nakamura, Daniel Pelletier, Alex Rovira, Mar Tintore, Anthony Traboulsee, Zia Choudhry, Nadia Daizadeh, Elizabeth Poole, Heinz Wiendl

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    • P0025 - Analysis fo the results of the establishment of a SARS-CoV-2 safety protocol for Multiple Sclerosis patients  (View Presentation)

      Keyword: Clinical Outcome Measures

      Virginia Meca-Lallana, Clara Aguirre, Carolina Díaz, Laura Cardeñoso, Angels Figuerola-Tejerina, Miguel Ruiz, Jose Vivancos

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    • P0026 - Analysis of association between expanded disability status scale and patient determined disease steps (View Presentation)

      Keyword: Clinical Outcome Measures

      Charles Makin, Arman Altincatal, Mark Gudesblatt, Bernd Kieseier, Carl De Moor

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    • P0027 - Are we ready for precision medicine in Multiple Sclerosis? A web-based survey across Europe   (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      filippo Martinelli Boneschi, Sandra D'Alfonso, Alessandra Caserini, Bernhard Hemmer, Elisabeth Celius, Pablo Villoslada, An Goris, Seema Kalra, Pentti Tienari, Fredrik Piehl, Ingrid Kockum

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    • P0028 - Assessing the temporal relationship of serum neurofilament light and subclinical disease activity: Findings from APLIOS trial (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Amit Bar-Or, Xavier Montalban, Roman Willi, Harald Kropshofer, Petra Kukkaro, Inga Ludwig, Martin Zalesak, Krishnan Ramanathan, Dieter A. Häring, Xixi Hu, Neva Coello, Morten Bagger, Edward Fox

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    • P0029 - Assessment of Multiple Sclerosis Severity Score and Age-Related Multiple Sclerosis Severity Score as health indicators in a population-based cohort (View Presentation)

      Keyword: Clinical Outcome Measures

      Laura Bau, Elisabet Matas, Lucía Romero-Pinel, Isabel León, Sergio Martínez-Yélamos, Antonio Martínez-Yélamos

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    • P0030 - Association of average blood cell telomere length with the clinical course of MS over a 10-year period (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Michael Hecker, Brit Fitzner, Kathrin Jäger, Jan Bühring, Margit Schwartz, Michael Walter, Uwe Zettl

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    • P0031 - Asymptomatic anterior optic pathway involvement in early multiple sclerosis and clinically isolated syndromes (View Presentation)

      Keyword: Clinical Outcome Measures

      Marco Pisa, Tommaso Croese, Gloria Dalla Costa, Simone Guerrieri, Su-Chun Huang, Lorena Fabbella, Annamaria Finardi, Bruno Colombo, Francesca Sangalli, Lucia Moiola, Vittorio Martinelli, Giancarlo Comi, Roberto Furlan, Letizia Leocani

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    • P0032 - Baseline serum Neurofilament light chain levels predict conversion to McDonald 2005 MS within 2 yrs of a first clinical demyelinating event in REFLEX (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      James Plested, Jens Kuhle, David Leppert, Giancarlo Comi, Nicola De Stefano, Ludwig Kappos, Mark Freedman, Delphine Issard, Sanjeev Roy

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    • P0033 - Baseline serum neurofilament light levels have prognostic value for on-study MRI activity: Results from ASCLEPIOS trials (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Jens Kuhle, Ludwig Kappos, Anne H. Cross, Roman Willi, Bingbing Li, Petra Kukkaro, Harald Kropshofer, Dieter A. Häring, Krishnan Ramanathan, Martin Merschhemke, Stephen Hauser

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    • P0034 - Can Digital Biomarkers Acquired on a Smarphone Distinguish Healthy Controls from Radiologically Isolated Syndrome Subjects? (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Mikael Cohen, Salim Fakir, Lydiane Mondot, Cassandre Landes, Christine Lebrun-Frenay

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    • P0035 - Can gait modelling predict disease progression in MS? A study using small body worn sensors in a clincial setting.  (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      David Paling, Lorenza Angelini, Ellen Buckley, Tecla Bonci, Alex Radford, Basil Sharrack, Siva Nair, Claudia Mazza

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    • P0036 - Cerebral hypometabolism is a marker of disease severity in multiple sclerosis: a non-invasive imaging study using T2-Relaxation-Under-Spin-Tagging MRI (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Olwen Murphy, Zixuan Lin, Grigorios Kalaitzidis, Eleni Vasileiou, Angeliki Filippatou, Kathryn Fitzgerald, Henrik Ehrhardt, Jeffrey Lambe, Elias Sotirchos, Blake Dewey, Yihao Liu, Jerry Prince, Peter Calabresi, Hanzhang Lu, Shiv Saidha

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    • P0037 - Change in serum neurofilament light chain levels: ENSEMBLE 1-year interim results (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Kiran Tailor, Robert Bermel, Thomas Berger, Bruno Brochet, Mark Freedman, Trygve Holmøy, Joep Killestein, Francesco Patti, Amy Perrin Ross, Timothy Vollmer, J Beltra, Regine Buffels, T Kuenzel, Hans Peter Hartung

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    • P0038 - CHIT1 at Diagnosis Reflects Long-Term Multiple Sclerosis Disease Activity (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Emanuela Oldoni, Ide Smets, Klara Mallants, Marijne Vandebergh, Lies Van Horebeek, Koen Poesen, Patrick Dupont, Bénédicte Dubois, An Goris

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    • P0039 - Circulating microRNAs as potential inflammatory biomarkers of acute exacerbation in relapsing-remitting multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Tatiana Koudriavtseva, Annunziata Stefanile, Sara Donzelli, Giovanni Blandino, Andrea Sacconi, Laura Conti, Svetlana Lorenzano, Silvana Zannino, Fulvia Pimpinelli, Giovanna D'Agosto, Enea Gino Di Domenico, Marta Maschio, Marco Salvetti, Matilde Inglese

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    • P0040 - Cladribine tablets versus other DMT in achieving disability improvement in relapsing remitting multiple sclerosis patients – network meta-analysis (View Presentation)

      Keyword: Clinical Outcome Measures

      Karolina Piasecka-Stryczynska, Miroslaw Rolka, Lukasz Kaczynski, Magdalena Gorecka, Rafal Wojcik, Iwona Adamek, Marcin Kaczor, Konrad Rejdak

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    • P0041 - Clinical characteristics and outcome of late onset Multiple Sclerosis (View Presentation)

      Keyword: Clinical Outcome Measures

      Ellen Iacobaeus, Anders Berglund, Kyla McKay, Lou Brundin, Jan Hillert

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    • P0042 - Clinical evolution of spasticity in adults with multiple sclerosis: systematic review (View Presentation)

      Keyword: Clinical Outcome Measures

      Tracey Jones-Hughes, Carlos Vila Silván, Joanna Campbell, Daniela Ortin Sulbaran, Richard Stork, Louise Crathorne

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    • P0043 - Clinical practice experience with Cladribine in Multiple Sclerosis (View Presentation)

      Keyword: Clinical Outcome Measures

      Virginia Meca-Lallana, Clara Aguirre, Javier Torres, Carolina Díaz, Beatriz Del Río, Rosalía Martín, Jose Vivancos

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    • P0044 - CogEval in the Real World: Feasibility, Implementation, and Real World Implications (View Presentation)

      Keyword: Clinical Outcome Measures

      John Kramer

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    • P0045 - Comorbidities present before the MS diagnosis are not predictors for progression (View Presentation)

      Keyword: Clinical Outcome Measures

      Marco De Caneda, Camila Batista, MARIA CECÍLIA De Vecino

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    • P0046 - Comparative Effectiveness of Ozanimod Versus Dimethyl Fumarate: Results of a Matching-Adjusted Indirect Comparison (View Presentation)

      Keyword: Clinical Outcome Measures

      Jenna Zeringo, Stanley Cohan, Jinender Kumar, Stella Arndorfer, Xuelian Zhu, Marko Zivkovic, Tom Tencer

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    • P0047 - Comparative Efficacy and Safety of Ozanimod Versus Teriflunomide for Relapsing-Remitting Multiple Sclerosis: a Matching-Adjusted Indirect Comparison (View Presentation)

      Keyword: Clinical Outcome Measures

      Jenna Zeringo, Stanley Cohan, Jinender Kumar, Stella Arndorfer, Xuelian Zhu, Marko Zivkovic, Tom Tencer

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    • P0048 - Comparative Efficacy of Relapsing Multiple Sclerosis Therapies: A Longitudinal Model-Based Meta-Analysis for Confirmed Disability Accumulation (View Presentation)

      Keyword: Clinical Outcome Measures

      Matthew Zierhut, Hilke Kracker, Tatiana Scherz, Alexander Keenan, Brian Hennessy

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    • P0049 - Comparative Efficacy of Relapsing Multiple Sclerosis Therapies: A Model-Based Meta-Analysis for Annual Relapse Rate (View Presentation)

      Keyword: Clinical Outcome Measures

      Matthew Zierhut, Hilke Kracker, Tatiana Scherz, Alexander Keenan, Brian Hennessy

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    • P0050 - Comparative transcriptomics of multiple sclerosis vs. viral infections, including SARS-CoV-2 (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      George Vavougios, Marianthi Breza, Theodoros Mavridis, Sotirios Zarogiannis, Karen Krogfelt, Erietta Sygkliti Pelidou, Triantafyllos Doskas

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    • P0051 - Comparison of serum and CSF fluid biomarkers for predicting long term disease progression in MS   (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Simon Thebault, Mohammad Abdoli, Seyed Mohammad Fereshtehnejad, Daniel Tessier, Vincent Tabard-Cossa, Mark Freedman

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    • P0052 - Completion rates by clinicians in global MS studies for the electronic EDSS compared to paper (View Presentation)

      Keyword: Clinical Outcome Measures

      Jenny Ly, Rinah Yamamoto

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    • P0053 - Correlation Between Spinal Fluid and Blood Levels of Neurofilament Light, GFAP, Tau, and UCHL1: Do We Need a Correction Factor? (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Enrique Alvarez, Alanna Ritchie, Kavita Nair, Robert Gross, Amanda Piquet, Courtney Knapp, Sean Selva, Stefan Sillau, Jeffrey Bennett, Greg Owens, Timothy Vollmer

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    • P0054 - Cost of a relapse-free patient in relapsing-remitting multiple sclerosis, a reliable result-based health indicator. (View Presentation)

      Keyword: Clinical Outcome Measures

      Lucía Romero-Pinel, Laura Bau, Elisabet Matas, Isabel León, Roser Juvany, Ramon Jódar, Antonio Martínez-Yélamos, Sergio Martínez-Yélamos

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    • P0055 - Cross-sectional and longitudinal estimation of radiographic and clinical endpoints to quantify MS disease trajectory with blood serum protein levels. (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Jens Kuhle, David Leppert, Pascal Benkert, Johanna Oechtering, Annette Orleth, Özgür Yaldizli, Michael Becich, Victor Gehman, Amal Katrib, Fatima Rubio Da Costa, Ferhan Qureshi, Cristina Granziera

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    • P0056 - CSF inflammatory profile of primary progressive multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Damiano Marastoni, Stefania Rossi, Anna Bolzan, Anna Pisani, Valentina Mazziotti, Marco Castellaro, Roberta Magliozzi, Salvatore Monaco, Massimiliano Calabrese

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    • P0057 - Decline in serum neurofilament is associated with decreased clinical and radiological disease activity over two years of dimethyl fumarate treatment (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Katja Akgün, Monique Schreiner, Justin Bohn, Kathryn Fitzgerald, Jordan Messer, Ellen Mowry, Elias Sotirchos, Peter Calabresi, Bernd Kieseier, Tjalf Ziemssen

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    • P0058 - Decrease of peripheral CD19+ IgG+ B-cells with age and immunotherapy in patients with relapsing remitting Multiple sclerosis. (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Tobias Keiner, Alexander Hapfelmeier, Bernhard Hemmer

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    • P0059 - Defining predictors of disease activity and worsening in multiple sclerosis: an analysis of the CombiRx trial (View Presentation)

      Keyword: Clinical Outcome Measures

      Yinan Zhang, Stacey Cofield, Gary Cutter, Stephen Krieger, Jerry Wolinsky, Fred Lublin

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    • P0060 - Descriptive study on recruitment effort for a remote monitoring study in Multiple Sclerosis: RADAR study (View Presentation)

      Keyword: Clinical Outcome Measures

      Ana Zabalza, Ana Isabel Guerrero, M Buron, Gloria Dalla Costa, M. L. La Porta, M. Martinis, Melinda Magyari, J. Melchert, L. Rosselli, Carlos Nos, Letizia Leocani, Per S. Sorensen, Xavier Montalban, Bernd Kieseier, Giancarlo Comi

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    • P0061 - Determining the effect of blood anticoagulants on the detection level of neurobiomarkers in headache and control patients on the SIMOA platform (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Alanna Ritchie, Sean Selva, Greg Owens, Courtney Knapp, Jose Parra Gonzalez, Enrique Alvarez, Kavita Nair, Timothy Vollmer

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    • P0062 - Developing standard data of cognitive function using Processing Speed Test in Japanese healthy volunteers and comparison to the US normative data (View Presentation)

      Keyword: Clinical Outcome Measures

      Masaaki Niino, Yusei Miyazaki, Michihiro Kanda, Michael Edwards, Carl De Moor, Arman Altincatal, James R. Williams, Bernd Kieseier, Stephen Rao

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    • P0063 - Development of a Custom Multivariate Proteomic Serum Based Assay for Association with Radiographic and Clinical Endpoints in MS (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Tanuja Chitnis, Michael Becich, Riley Bove, Bruce Cree, Victor Gehman, Refugia Gomez, Stephen Hauser, Roland Henry, Amal Katrib, Hrishikesh Lokhande, Jorge Oksenberg, Anu Paul, Ferhan Qureshi, Adam Santaniello, Neda Sattarnezhad, Shrishti Saxena, Howard Weiner, Michael Wilson, Hajime Yano, Sergio Baranzini

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    • P0064 - Development of the international, multidisciplinary, patient-relevant standard outcome set for Multiple Sclerosis: the S.O.S.MS project (View Presentation)

      Keyword: Clinical Outcome Measures

      Kirsten Daniels

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    • P0065 - Differential neuroinflammation genes expression in benign and highly active multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Maria Ivanova, Anastasya Voronkova, Maria Zakharova

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    • P0066 - Dimethyl fumarate decreases serum neurofilament light chain in relapsing-remitting multiple sclerosis patients. (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Susana Sainz de la Maza, Paulette Esperanza Walo Delgado, Noelia Villarrubia, Enric Monreal, Mercedes Espiño, Jose Ignacio Fernandez-Velasco, Jaime Masjuan, Lucienne Costa-Frossard, Luisa María Villar

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    • P0067 - Disability improvement by Multiple Sclerosis Functional Composite in progressive MS patients and MRI features (View Presentation)

      Keyword: Clinical Outcome Measures

      Tanuja Chitnis, Matthew McAdams, Mark Anderson, Mariann Polgar-Turcsanyi, Mattia Rosso, Bonnie Glanz, Taylor Saraceno, Ralph Kern, Susan Ward, Munish Mehra, Howard Weiner, Brian Healy

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    • P0068 - Disability Progression in MS Participants Treated with Delayed-release Dimethyl Fumarate: Age-related Subgroup Analysis of the NARCOMS Registry (View Presentation)

      Keyword: Clinical Outcome Measures

      Amber Salter, Samantha Lancia, Gary Cutter, Robert Fox, Ruth-Ann Marrie, Jason Mendoza, James Lewin

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    • P0069 - dreams: developing a comprehensive, sensitive and validated set of digital biomarkers for MS (View Presentation)

      Keyword: Biosensors

      Yvonne Naegelin, Johannes Lorscheider, Tim Woelfle, Silvan Pless, Jens Kuhle, Oscar Reyes, Andrea Wiencierz, Ludwig Kappos

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    • P0070 - Effect of evobrutinib, a BTK inhibitor, on immune cell and immunoglobulin levels in relapsing MS: an open-label extension to a phase II study (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Xavier Montalban, Jamie Shaw, Fernando Dangond, Emily Martin, Roland Grenningloh, Martin Weber, Ying Li

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    • P0071 - Effect of oral ponesimod on clinical disease activity and MRI-based outcomes in patients with relapsing multiple sclerosis: Phase 3 OPTIMUM study (View Presentation)

      Keyword: Clinical Outcome Measures

      Priya Ganpathy, Ludwig Kappos, Michel Burcklen, Mark Freedman, Robert Fox, Eva Kubala Havrdová, Brian Hennessy, Reinhard Hohlfeld, Fred Lublin, Xavier Montalban, Carlo Pozzilli, Tatiana Scherz, Philippe Linscheid, Magdalena Pirozek-Lawniczek, Lisa Ford, Hilke Kracker, Jens Wuerfel, Till Sprenger

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    • P0072 - Effect of switching disease modifying drugs on relapse rate in stable relapsing remitting multiple sclerosis patients planning for pregnancy. (View Presentation)

      Keyword: Clinical Outcome Measures

      Lubna Almouzain, Fiona Hamilton, Fiona Stevenson, Declan Chard, Nur Abdulrahman

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    • P0073 - Effectiveness of peginterferon beta-1a versus non-pegylated interferons and glatiramer acetate in a real-world setting using propensity score matching (View Presentation)

      Keyword: Clinical Outcome Measures

      Stefan Braune, Arnfin Bergmann, Fabian Roßnagel, Kirsi Taipale, Fabio Pellegrini, Thijs Koster, Karin Rehberg-Weber

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    • P0074 - Effects of Ocrelizumab on Cognition-Real World Evidence Using the CogEval App (View Presentation)

      Keyword: Clinical Outcome Measures

      John Kramer

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    • P0075 - Efficacy of Rituximab in Adult and Pediatric Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease: A Systematic Review and Meta-analysis (View Presentation)

      Keyword: Clinical Outcome Measures

      Smathorn Thakolwiboon, Jie Pan, Amputch Karukote, Hannah Zhao-Fleming, Mirla Avila

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    • P0076 - Evaluation of diagnosis and treatment practices in patients with Multiple Sclerosis by Brazilian neurologists’ experts in demyelinating disorders. (View Presentation)

      Keyword: Clinical Outcome Measures

      Cássia Elisa Marin, Dagoberto Callegaro, Marco Aurélio Lana-Peixoto, Óscar Fernández, Antônio Pereira Gomes Neto, Cláudia Cristina Ferreira Vasconcelos, José Artur Costa D’almeida, Marcus Vinícius Magno Gonçalves, Maria Fernanda Mendes, Mônica Koncke Fiuza Parolin, Osvaldo Nascimento, Paulo Diniz Gama, Rafael Paternó Castello Dias-Carneiro, Ronaldo Maciel Dias, Alfredo Damasceno, Jefferson Becker

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    • P0077 - Evaluation of Quality of Life and Fatigue in Patients Followed in Multiple Sclerosis Outpatient Clinic (View Presentation)

      Keyword: Clinical Outcome Measures

      Gençer Genç, Ülgen Yalaz Tekan, Esin Ayşe Özbek, Nazan Konakçı, Serpil Bulut

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    • P0078 - Evidence for the efficacy of nabiximols oromucosal spray in the management of patients with spasticity: A systematic review (View Presentation)

      Keyword: Clinical Outcome Measures

      Louise Crathorne, Joanna Campbell, Carlos Vila Silván, Richard Stork, Daniela Ortin Sulbaran

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    • P0079 - Experience in Multiple Sclerosis Patients with SARS CoV-2 Infection (View Presentation)

      Keyword: Clinical Outcome Measures

      Virginia Meca-Lallana, Clara Aguirre, Carolina Díaz, Beatriz Del Río, Rosalía Martín, Jose Vivancos

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    • P0080 - Exploring neurofilament light in CSF as a biomarker for multiple sclerosis in clinical practice (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Igal Rosenstein, Lenka Novakova, Markus Axelsson, Kaj Blennow, Henrik Zetterberg, Jan Lycke

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    • P0081 - Exploring the usability and patient satisfaction of a virtual rehabilitation program in multiple sclerosis: The RehabVR study protocol (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Daniel Prefasi , Virginia Meca-Lallana, Walter Alabarcez, Teresa Hernandez, Fabiola Garcia, Angelica Portaña, David Gomis, Nieves Tellez, Cristina Garcia-Bernaldez, Jorge Mauriño, Nicolas Medrano, Aranzazu Vazquez

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    • P0082 - From proteome to interactome: a mechanistic approach to MS biomarker discovery (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Amal Katrib, Ferhan Qureshi, Michael Becich, Victor Gehman, Susan Goelz

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    • P0083 - Gadolinium improves detection of central vein lesions in MS using 3T FLAIR*. (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Lynn Daboul, Carly O'Donnell, David Moreno-Dominguez, Paulo Rodrigues, John Derbyshire, Christina Azevedo, Amit Bar-Or, Eduardo Caverzasi, Peter Calabresi, Bruce Cree, Leorah Freeman, Roland Henry, Erin Longbrake, Jiwon Oh, Nico Papinutto, Daniel Pelletier, Rohini Samudralwar, Matthew Schindler, Elias Sotirchos, Nancy Sicotte, Andrew Solomon, Russell Shinohara, Daniel Reich, Pascal Sati, Daniel Ontaneda

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    • P0084 - Gene expression profiling and TCR diversity of ATA188, an off-the-shelf, allogeneic EBV-targeted T-cell immunotherapy for progressive MS (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Claire Jones, P Foubert, S Srihari, L Le Texier, R R Shen, F Forozan, C Smith, R Khanna, B T Aftab

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    • P0085 - Harmonization of real-world studies in multiple sclerosis: retrospective analysis from the RIReMS group (View Presentation)

      Keyword: Clinical Outcome Measures

      Marcello Moccia, Pietro Annovazzi, Maria Chiarav Buscarinu, Massimiliano Calabrese, Paola Cavalla, Cinzia Cordioli, Massimiliano Di Filippo, Diana Ferraro, Alberto Gajofatto, Antonio Gallo, Roberta Lanzillo, Alice Laroni, Loredana Lorefice, Simona Malucchi, Viviana Nociti, Damiano Paolicelli, Federica Pinardi, Luca Prosperini, Marta Radaelli, Paolo Ragonese, Valentina Tomassini, Carla Tortorella, Eleonora Cocco, Claudio Gasperini, Claudio Solaro

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    • P0086 - Highly sensitive quantitation of CXCL13 as an intrathecal biomarker in optic neuritis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Mads Nikolaj Olesen, Anna Christine Nilsson, Gorm Pihl-Jensen, Kerstin Kathrine Soelberg, Dorte Aalund Olsen, Ivan Brandslund, Søren Thue Lillevang, Jonna Skov Madsen, Jette Lautrup Frederiksen, Nasrin Asgari

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    • P0087 - Identification of proteins associated with ageing in patients with progressive multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Nicolás Fissolo, Luciana Midaglia, Begoña Oliver, Luisa María Villar, Antonio José Sánchez-López, Albert Saiz, Roberto Alvarez-Lafuente, Lluís Ramió I Torrentà, Sergio Martínez-Yélamos, Xavier Montalban, Manuel Comabella

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    • P0088 - Identification of putative multiple sclerosis biomarkers in CSF by targeted-mass spectrometry (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Dorsa Sohaei, Simon Thebault, Ihor Batruch, Ioannis Prassas, Mark Freedman, Eleftherios Diamandis

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    • P0089 - IFP35 as biomolecular marker of neuroinflammation and treatment response in Multiple Sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Roberto De Masi, Stefania Orlando

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    • P0090 - Immune cell profiles associated with CIS progression and stability using RNA-seq single-cell analysis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      James Giarraputo, Vaibhav Jain, Stephanie Arvai, Dawn Smilek, Kristina Harris, Simon Gregory

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    • P0091 - Improving patient outcomes through a comprehensive care management platform (MOVING MS) (View Presentation)

      Keyword: Clinical Outcome Measures

      Annalise Miner, Michael Becich, Victor Gehman, Jennifer Graves

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    • P0092 - Incidence of recurrence of disease activity after fingolimod discontinuation in older patients (View Presentation)

      Keyword: Clinical Outcome Measures

      Vasiliki Pantazou, Caroline Pot, Geraldine Le Goff, Renaud Du Pasquier, Marie Theaudin

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    • P0093 - Increased serum GFAP associates with microstructural white matter damage in multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Maija Saraste, Svetlana Bezukladova, Markus Matilainen, Marcus Sucksdorff, Jens Kuhle, David Leppert, Laura Airas

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    • P0094 - Inter-laboratory evaluation of cerebrospinal fluid and serum kappa free light chain measurements (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Diana Ferraro, Roberta Bedin, Patrizia Natali, Diego Franciotta, Gaetano Bernardi, Elena Corsini, Eleonora Cocco, Gianna Costa, Ilaria Crespi, Marta Lamonaca, Arianna Sala, Cinzia Nicolò, Massimiliano Di Filippo, Alfredo Villa, Viviana Nociti, Teresa De Michele, Paola Cavalla, Paola Caropreso, Francesca Vitetta, Matteo Gastaldi, Tommaso Trenti, Stefano Meletti, Patrizia Sola

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    • P0095 - Intracortical motor conduction is associated with dexterity in progressive multiple sclerosis (View Presentation)

      Keyword: Clinical Outcome Measures

      Marco Pisa, Raffaella Chieffo, Martina Congiu, Federica Esposito, Marzia Romeo, Mauro Comola, Giancarlo Comi, Letizia Leocani

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    • P0096 - Intrathecal immunoglobulin M synthesis is associated with higher disease activity and severity in Multiple Sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Johanna Oechtering, Sabine Schaedelin, Pascal Benkert, Stefanie Müller, Lutz Achtnichts, Jochen Vehoff, Giulio Disanto, Oliver Findling, Bettina Fischer-Barnicol, Annette Orleth, Andrew Chan, Anke Salmen, Caroline Pot, Cristina Granziera, Ingmar Heijnen, Patrice Lalive, Jens Wuerfel, Therese Lincke, Johanna Lieb, Özgür Yaldizli, Tim Sinnecker, Tobias Derfuss, Axel Regeniter, Chiara Zecca, Claudio Gobbi, Ludwig Kappos, David Leppert, Jens Kuhle

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    • P0097 - Intrathecal immunoglobulin M synthesis is associated with higher serum neurofilament light chain levels and increased MRI disease activity in MS (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Johanna Oechtering, Sabine Schaedelin, Pascal Benkert, Muhamed Barakovic, Aleksandra Maceski, Annette Orleth, Dimitri Rey, Tim Sinnecker, Reza Rahmanzadeh, Sabrina Zadic, Riccardo Galbusera, Ramona-Alexandra Todea, Alessandro Cagol, Lutz Achtnichts, Stefanie Aeschbacher, Klaus Berger, Andrew Chan, David Conen, Tobias Derfuss, Giulio Disanto, Oliver Findling, Bettina Fischer-Barnicol, Ingmar Heijnen, Kevin Hrusovsky, Harald Kropshofer, Patrice Lalive, Johanna Lieb, Therese Lincke, Johannes Lorscheider, Pietro Maggi, Christian Müller, Stefanie Müller, Yvonne Naegelin, Jorge Oksenberg, Caroline Pot, Renaud Du Pasquier, Ernst-Wilhelm Radue, Axel Regeniter, Anke Salmen, Jochen Vehoff, Emmanuelle Waubant, Sven Wellmann, Heinz Wiendl, Jens Würfel, Özgür Yaldizli, Chiara Zecca, David Leppert, Claudio Gobbi, Ludwig Kappos, Cristina Granziera, Jens Kuhle

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    • P0098 - Investigation of biomarkers in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Burak Arslan, Gökçe Arslan, Aylin Dinçel, R Karabudak, Aslı Tuncer

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    • P0099 - Is disease activity prior to fingolimod initiation in treatment-naive patients predictive of response?  (View Presentation)

      Keyword: Clinical Outcome Measures

      Vasiliki Pantazou, Renaud Du Pasquier, Geraldine Le Goff, Caroline Pot, Marie Theaudin

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    • P0100 - Italian prospective multicentric observational real-life study of aggressive Relapsing Remitting Multiple Sclerosis treated with alemtuzumab (View Presentation)

      Keyword: Clinical Outcome Measures

      Lucia Moiola, Maria Di Cristinzi, Andrea Sultana, Chiara Zanetta, Francesca Rinaldi, LAURA Brambilla, Jessica Frau, Simona Malucchi, Pietro Annovazzi, giorgia Puorro, Assunta Bianco, Giacomo Lus, Paola Cavalla, Francesca Sangalli, Marzia Romeo, Gerola Marfia, Antonio Gallo, Valeria Barcella, Sebastiano Bucello, Maria Teresa Ferrò, caterina Lapucci, Luca Chiveri, Clara Grazia Chisari, Eleonora Baldi, Raffaella Clerici, Paola Banfi, carla Tortorella, Rocco Totaro, Raffaella Cerqua, Simone Tonietti, Vittorio Mantero, Giuseppe Santuccio, Massimo Filippi

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    • P0101 - Kinematic assessment of upper limb function in progressive multiple sclerosis (View Presentation)

      Keyword: Biosensors

      Linford Fernandes, Awais Hafeez, Rachel Coats, Mark Mon-Williams, Helen Ford

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    • P0102 - KonectomTM smartphone-based digital outcome assessment of cognitive and motor function in multiple sclerosis (View Presentation)

      Keyword: Clinical Outcome Measures

      Christine Guo, Ellen Cahir-Mcfarland, Julien Dumail, Thibaud Guymard, Jenna McLoughlin, Séverine Bieuvelet, Morgane Vallée, Saad Zinaï, Vanessa Beynon, Matt Scaramozza, Nathalie Franchimont, Shibeshih Belachew

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    • P0103 - Liothyronine treatment of MS patients alters proteins in CSF related to angiogenesis and immune function (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Pavan Bhargava, Thomas Shoemaker, Sarah Snoops, Sandra Cassard, Fan Tian, Kathryn Fitzgerald, David Cooper, Jenna Mammen, Ellen Mowry, Peter Calabresi, Scott Newsome

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    • P0104 - Long term disability trajectories in multiple sclerosis: a group-based trajectory analysis of the AusLong cohort (View Presentation)

      Keyword: Clinical Outcome Measures

      Mohammad Hussain, Ingrid Van Der Mei, Robyn Lucas, Anne-Louise Ponsonby, Bruce Taylor

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    • P0105 - Longitudinal proteomic analysis of MS patients before and after autologous hematopoietic stem cell transplantation (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Simon Thebault, Seyed Mohammad Fereshtehnejad, Veronique Laforte, Mark Freedman, David Juncker, Amit Bar-Or

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    • P0106 - Long-term single-centre experience with natalizumab. (View Presentation)

      Keyword: Clinical Outcome Measures

      Pierre Duquette, Pierre-Olivier Despault, Elaine Roger, Alexandre Prat, Catherine Larochelle, Marc Girard

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    • P0107 - Lymphocyte response in standard and extended interval dosing of natalizumab (View Presentation)

      Keyword: Clinical Outcome Measures

      Shameer Rafee, Laura Kennelly, Chris McGuigan

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    • P0108 - Meta-analysis of randomized controlled trials and real-world evidence comparing natalizumab and fingolimod for relapsing-remitting multiple sclerosis (View Presentation)

      Keyword: Clinical Outcome Measures

      Christina Eavis, Orestis Efthimiou, Carlos Acosta, Patrick Saunders-Hastings, Fabio Pellegrini

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    • P0109 - microRNA expression and its association with disability and brain atrophy (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Carlos Lopez De Silanes, Yolanda Aladro Benito, Laura De Torres, Ignacio Casanova, Sara Abellán Ayuso, Silvia Pérez-Pérez, María Ángel García-Martínez, Miriam Eimil Ortiz, Beatriz Oyanguren Rodeño, María José Gil Moreno, Rodrigo Terrero Carpio, Miguel Ángel Saiz Sepúlveda, Blanca Patricia Diaz Montoya, Esther De Antonio Sanz, Marta González Salaices, María Inmaculada Domínguez-Mozo, Roberto Alvarez-Lafuente

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    • P0110 - Modulation of cerebrospinal fluid immunoglobulins by ocrelizumab treatment (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Michelle Gheen, Martin Weber, H.-Christian Von Büdingen, Amit Bar-Or, Ann Herman, Chris Harp, Jinglan Pei, Ryan Winger, Jeffrey Bennett, Robert Carruthers, Keith Edwards, Robert Fallis, Jeffrey Gelfand, Paul Giacomini, Benjamin Greenberg, David A. Hafler, Erin Longbrake, Carolina Ionete, Ulrike W Kaunzner, Christopher Lock, Gabriel Pardo, Fredrik Piehl, Tjalf Ziemssen, Anne H. Cross

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    • P0111 - Monitoring Multiple Sclerosis Treatment with Plasma Biomarkers: NfL, GFAP, UCH-L1, and Tau (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Robert Gross, Alanna Ritchie, Sean Selva, Jose Parra Gonzalez, Courtney Knapp, Stefan Sillau, Greg Owens, Kavita Nair, Timothy Vollmer, Enrique Alvarez

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    • P0113 - MRI activity as a predictor of suboptimal response to natalizumab treatment: single center prospective cohort trial (View Presentation)

      Keyword: Clinical Outcome Measures

      Dmitry Kasatkin, Nikolay Spirin, Natalya Spirina, Ekaterina Kiseleva, Svetlana Molchanova

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    • P0114 - MS Biomarker Discovery: a multi-modal approach to identify biomarkers of myelin repair by leveraging a preclinical rodent model of MS (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Yea Jin Kaeser-Woo, Elena Morozova, Peter Cheng-te Chou, Wanyong Zeng, Bin Wang, Jessica Dion, Brian Harvey, David Koske, Dan Ferretti, Hui-Hsin Tsai, Daniel P. Bradley, Kirsten Sigrist, Raja Sriperumbudur, Tzu-Ying Liu, Wenting Wang

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    • P0115 - mSteps: A pilot study using a phone application with GPS, accelerometers and Wi-Fi positioning to measure walking distance in MS, indoors and outdoors (View Presentation)

      Keyword: Clinical Outcome Measures

      Sarah Alexander, Marie Braisher, Carmen Tur, Jeremy Chataway

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    • P0116 - Multiple Sclerosis and Cognitive Impairment: Computerized Cognitive Assessment and PROMIS-Cognitive Function Questionnaire: An Unfulfilled Promis (View Presentation)

      Keyword: Clinical Outcome Measures

      Olivia Kaczmarek, Jared Srinivasan, Myassar Zarif, Barbara Bumstead, Marijean Buhse, Daniel Golan, Jeffery Wilken, kaitlyn Jaenicke, Wendy Doroski, Deborah Lund, Mark Gudesblatt

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    • P0117 - Mystery of MRZ reaction in multiple sclerosis   (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Samuel Wachamo, RUTURAJ Masvekar, Peter Kosa, Mihael Varosanec, Bibiana Bielekova

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    • P0118 - Neurofilament light chain concentration predicts risk of relapse in participants with relapsing multiple sclerosis in phase 3 ozanimod trials (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Johanna Moore, Sarah Harris, Giancarlo Comi, Bruce Cree, Douglas L Arnold, Lawrence Steinman, James Sheffield, Harry Southworth, Ludwig Kappos, Jeffrey Cohen

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    • P0119 - Neurofilament light chain levels correlate with lesion activity and axonal damage in MS (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Aletta Van Den Bosch, Nina Fransen, Matthew Mason, Annemieker Rozemuller, Charlotte Teunissen, Joost Smolders, Inge Huitinga

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    • P0120 - Neuroperformance test outcomes as predictors of employment in a large, heterogeneous real world MS populations: Results from MS PATHS (View Presentation)

      Keyword: Clinical Outcome Measures

      Carl De Moor, James Williams, Lauren Krupp, Marisa McGinley, Kathryn Fitzgerald, Stephen Rao, Richard Rudick

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    • P0121 - Objective measurement of speech correlates with disease status and quality of life in people with MS without dysarthria (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Gustavo Noffs, Frederique Boonstra, Thushara Perera, Helmut Butzkueven, Scott Kolbe, Fernanda Maldonado, Eduardo Lizama, Mary Galea, Jim Stankovich, Andrew Evans, Adam Vogel, Anneke Van Der Walt

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    • P0122 - Ocrelizumab in patients with multiple sclerosis: A single center experience.  (View Presentation)

      Keyword: Clinical Outcome Measures

      Chad Brady, Dhairya Lakhani, Bob Hou, Jeffery Carpenter, Weidong Luo, Sebastian Magda, Robert Haxton, Richa Tripathi, Gerard Deib, Shitiz Sriwastava

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    • P0123 - Ocrelizumab reduces thalamic volume loss and clinical progression in PPMS and RMS independent of baseline NfL and other measures of disease severity (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Michelle Gheen, Amit Bar-Or, Gian Thanei, Chris Harp, Corrado Bernasconi, Ulrike Bonati, Anne H. Cross, Sally Fischer, Laura Gaetano, Stephen Hauser, Robert Hendricks, Jens Kuhle, David Leppert, Fabian Model, Harold Koendgen, Xiaoming Jia, Ann Herman

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    • P0124 - Ocrelizumab treatment in patients with relapsing-remitting multiple sclerosis: a single-center real-world experience (View Presentation)

      Keyword: Clinical Outcome Measures

      Caterina Lapucci, Giacomo Boffa, Maria Cellerino, Giovanni Novi, elvira Sbragia, nicolò Bruschi, Elisabetta Mancuso, francesco Tazza, Alice Laroni, Elisabetta Capello, Antonio Uccelli, Matilde Inglese

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    • P0125 - Ocrelizumab treatment induces a sustained blood NfL reduction in patients with PPMS and RMS (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Michelle Gheen, Amit Bar-Or, Gian Thanei, Chris Harp, Corrado Bernasconi, Ulrike Bonati, Anne Cross, Sally Fischer, Laura Gaetano, Stephen Hauser, Robert Hendricks, Jens Kuhle, David Leppert, Fabian Model, Harold Koendgen, Xiaoming Jia, Ann Herman

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    • P0126 - Olfactory threshold as a biomarker predicting treatment response in relapsing multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Gabriel Bsteh, Harald Hegen, Klaus Berek, Anne Zinganell, Sebastian Wurth, Michael Auer, Franziska Di Pauli, Florian Deisenhammer, Thomas Berger

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    • P0127 - Oral therapies for treatment of relapsing-remitting multiple sclerosis in Austria (View Presentation)

      Keyword: Clinical Outcome Measures

      Michael Guger, Christian Enzinger, Fritz Leutmezer, Jörg Kraus, Stefan Kalcher, Erich Kvas, Thomas Berger

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    • P0128 - Outcomes in Alemtuzumab-Treated Patients With Thyroid Adverse Events: 6-Year Pooled CARE-MS Data (View Presentation)

      Keyword: Clinical Outcome Measures

      Cameron Duvall, Colin Dayan, Beatriz Lecumberri, Ilaria Muller, Sashiananthan Ganesananthan, Samuel Hunter, Krzysztof Selmaj, Hans Peter Hartung, Eva Havrdova, Christopher Laganke, Tjalf Ziemssen, Bart Van Wijmeersch, Sven Meuth, David Margolin, Salman Afsar, Nadia Daizadeh, Elizabeth Poole, Darren Baker, Peter Senior

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    • P0129 - Pattern of brain attack occurrence in neuromyelitis optica spectrum disorder: effect of treatment   (View Presentation)

      Keyword: Clinical Outcome Measures

      Min Young Lee, Jae-Won Hyun, Su-Hyun Kim, Ho Jin Kim

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    • P0130 - Pediatric MS: different disease course, different impact, different measurement approach needed (View Presentation)

      Keyword: Clinical Outcome Measures

      Nikki Ow, Avi Karp, Joe Ogeil, Marie-Emmanuelle Dilenge, Guillaume Sébire, Nancy Mayo

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    • P0131 - Predicting long-term sustained disability progression in multiple sclerosis: application in the CLARITY trial (View Presentation)

      Keyword: Clinical Outcome Measures

      Sifat Sharmin, Francesca Bovis, Maria Pia Sormani, Helmut Butzkueven, Tomas Kalincik

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    • P0132 - Prediction of 15-year MS outcomes in BENEFIT trial patients using serum neurofilament light chain concentrations (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Beth Gates, Jens Kuhle, Ludwig Kappos, Mark Freedman, Gilles Edan, Xavier Montalban, Hans Peter Hartung, Frederik Barkhof, Ralf Koelbach, Eva-Maria Wicklein

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    • P0133 - Prediction of MS disability status in Japanese claims database using principal component analysis (View Presentation)

      Keyword: Clinical Outcome Measures

      Hiromichi Otaka, Kengo Ueda, Kosuke Iwasaki, Tomomi Takeshima, Izumi Kawachi

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    • P0134 - Preliminary validation of static posturography as a disability outcome measure in progressive multiple sclerosis. (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Siew Mei Yap, Mark S Etzelmueller, Clodagh O'Keeffe, Maria Gaughan, Richard B Reilly, Christopher McGuigan

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    • P0135 - Preventing multiple sclerosis misdiagnosis using the “central vein sign”: A real-world study (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Marwa Kaisey, Andrew Solomon, Brooke Guerrero, Brian Renner, Zhaoyang Fan, Natalie Ayala, Michael Luu, Marcio Diniz, Pascal Sati, Nancy Sicotte

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    • P0136 - Profiling of small non-coding RNAs across cellular and biofluid compartments in patients with Multiple Sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Galina Zheleznyakova, Eliane Piket, Maria Needhamsen, Michael Hagemann-Jensen, Diana Ekman, Mohsen Khademi, Faiez Al Nimer, Patrick Scicluna, Omid Faridani, Tomas Olsson, Fredrik Piehl, Maja Jagodic

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    • P0137 - Prognostic value of NK/T ratios for disease activity in multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Max Mimpen, Anne-Hilde Muris, Linda Rolf, Oliver Gerlach, Jens Kuhle, Raymond Hupperts, Joost Smolders, Jan Damoiseaux

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    • P0138 - "Progressive Multifocal Leukoencephalopathy outcomes in Multiple Sclerosis: A Systemic review and Metanalysis "  (View Presentation)

      Keyword: Clinical Outcome Measures

      Shitiz Sriwastava, Shaghayegh Kazemlou, Hamidreza Saber, Samiksha Srivastava, Sarah Peterson, Ronald Gwinn, Saurabh Kataria, Richa Tripathi, Zubeda Sheikh, Sijin Wen, Si Gao, Dhairya Lakhani, Evanthia Bernitsas

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    • P0139 - Real World Clinical and Imaging Outcomes in Relapsing MS Patients treated with Alemtuzumab in a US Regional MS Center (View Presentation)

      Keyword: Clinical Outcome Measures

      Duy-Tan Tran, Bhupendra Khatri, Christine Murphy, Lisa Sershon, Omotayo Olapo, Toni Perea, Sara Beals, Lindman Lindman, Elizabeth Poole, Risako Robinson, Avani Patel, Roopali Gandhi, Lobat Hashemi

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    • P0140 - Real World Experience of Oral Immune Reconstitution therapy (Cladribine) in the treatment of multiple sclerosis in the United Arab Emirates (View Presentation)

      Keyword: Clinical Outcome Measures

      Mona Thakre, Jihad Inshasi

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    • P0141 - Real-world data on the use of Ocrelizumab, among MS patients: B-cell suppression and clinical outcomes. (View Presentation)

      Keyword: Clinical Outcome Measures

      Charmaine Neo, Victoria Singh-Curry, Ashwini Nandoskar, Omar Malik, Rachel Dorsey, Paolo Muraro, Richard Nicholas, Antonio Scalfari

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    • P0142 - Real-world effectiveness of dimethyl fumarate versus fingolimod using novel outcomes in a heterogeneous patient cohort (View Presentation)

      Keyword: Clinical Outcome Measures

      Carrie Hersh, Yang Lei, Arman Altincatal, Carl De Moor, Richard Rudick, James R. Williams, Catherine Miller, Bernd Kieseier, Irene Koulinska

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    • P0143 - Real-World Experience in RRMS and SPMS Patients with Higher Disability and Substantial Lymphopenia Switching from Prior DMTs to Teriflunomide (View Presentation)

      Keyword: Clinical Outcome Measures

      Duy-Tan Tran, Regina Berkovich, Nupur Greene, Michael Fernandez, Sam Fadaee, Cuc Quach, Yelena Pyatkevich

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    • P0144 - Real-world outcomes in patients with relapsing forms of multiple sclerosis treated with intramuscular interferon beta-1a or peginterferon beta-1a (View Presentation)

      Keyword: Clinical Outcome Measures

      Christina Eavis, Amber Salter, Samantha Lancia, Gary Cutter, Robert Fox, Ruth Ann Marrie, Robin Avila, Megan Vignos

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    • P0145 - Relation of EDSS to patient-reported outcome measurements in MS: Real-world data from a Swedish nationwide study of fingolimod (IMSE 2) (View Presentation)

      Keyword: Clinical Outcome Measures

      Åsa Leandersson, Stina Kågström, Linda Forsberg, Jan Hillert, Petra Nilsson, Charlotte Dahle, Anders Svenningsson, Jan Lycke, Anne-Marie Landtblom, Joachim Burman, Claes Martin, Peter Sundström, Martin Gunnarsson, Fredrik Piehl, Tomas Olsson

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    • P0146 - Reliability, concurrent and ecological validity of smartphone-based cognition and walking tests (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Ka Hoo Lam, Pim Van Oirschot, Frank Dorssers, Bram Den Teuling, Bernard Uitdehaag, Vincent De Groot, Joep Killestein

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    • P0148 - Retinal layer thinning is reflecting disability progression independent of relapse activity in multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Gabriel Bsteh, Harald Hegen, Patrick Altmann, Klaus Berek, Sebastian Wurth, Michael Auer, Anne Zinganell, Franziska Di Pauli, Paulus Rommer, Fritz Leutmezer, Florian Deisenhammer, Thomas Berger

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    • P0149 - Retinal layer thinning rate as a biomarker predicting treatment response in relapsing multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Gabriel Bsteh, Harald Hegen, Klaus Berek, Patrick Altmann, Sebastian Wurth, Michael Auer, Anne Zinganell, Franziska Di Pauli, Paulus Rommer, Fritz Leutmezer, Florian Deisenhammer, Thomas Berger

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    • P0150 - REWORD-MS: REal WOrld study to assess the Response to Dimethyl fumarate in patients with Multiple Sclerosis (View Presentation)

      Keyword: Clinical Outcome Measures

      Maria Francesca Creta, Irene Tramacere, Eugenia Tomas Roldan, Paolo Confalonieri, Valentina Torri Clerici, Carlo Antozzi, Renato Mantegazza, Alessandra Tozzo, Laura Brambilla

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    • P0151 - Serum contactin-1 levels as a biomarker of long-term disease progression in natalizumab-treated multiple sclerosis. (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Zoë Van Lierop, Luuk Wieske, Eline Willemse, Iris Dekker, Cyra Leurs, Marleen Koel-Simmelink, Bastiaan Moraal, Frederik Barkhof, Bernard Uitdehaag, Joep Killestein, Charlotte Teunissen

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    • P0152 - Serum Neurofilament levels of multiple sclerosis patients before and after treatment with injectable therapies (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      André Huss, Makbule Senel, Ahmed Abdelhak, Benjamin Mayer, Jan Kassubek, Albert Ludolph, Markus Otto, Hayrettin Tumani

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    • P0153 - Serum neurofilament light chain and retinal layer thickness measurements are complementary predictors of disease activity in early multiple sclerosis. (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Ting-Yi Lin, Viktoriya Vitkova, Ivette Serra, Robyn Cunningham, Susanna Asseyer, Seyedamirhosein Motamedi, Jens Kuhle, Judith Bellmann-Strobl, Klemens Ruprecht, Friedemann Paul, Alexander Brandt, Hanna Zimmermann

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    • P0154 - Serum Neurofilament light chain captures and predicts disability progression independent of relapses (PIRA) in multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Johannes Lorscheider, Pascal Benkert, Özgür Yaldizli, Giulio Disanto, Johanna Oechtering, Sabine Schädelin, Jens Würfel, Andrew Chan, Lutz Achtnichts, Oliver Findling, Tobias Derfuss, Harald Kropshofer, Annette Orleth, Bettina Fischer-Barnicol, Aleksandra Maceski, Dimitri Rey, Sabrina Zadic, Christian Müller, Stefanie Aeschbacher, Emmanuelle Waubant, Jorge Oksenberg, Sven Wellmann, Heinz Wiendl, Ludwig Kappos, Anke Salmen, Robert Hoepner, Patrice Lalive, Renaud Du Pasquier, Caroline Pot, Pietro Maggi, Chiara Zecca, Yvonne Naegelin, Stefanie Müller, Kevin Hrusovsky, Klaus Berger, David Conen, Muhamed Barakovic, Tim Sinnecker, Claudio Gobbi, Cristina Granziera, David Leppert, Jens Kuhle

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    • P0155 - Serum neurofilament light chain levels correlate with attack-related disability in neuromyelitis optica spectum disorder (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Ian Williams, Orhan Aktas, Hans Peter Hartung, Michael Smith, William Rees, Kazuo Fujihara, Friedemann Paul, Romain Marignier, Jeffrey Bennett, Ho Jin Kim, Brian Weinshenker, Sean Pittock, Dean Wingerchuk, Gary Cutter, Ari Green, Maureen Mealy, Jorn Drappa, Dewei She, Daniel Cimbora, John Ratchford, Eliezer Katz, Bruce Cree

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    • P0156 - Serum neurofilament light levels correlate with reduced grey matter volume in advanced multiple sclerosis. (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Arabella Buchmann, Lukas Pirpamer, Daniela Pinter, Maragarete Voortman, Birgit Helmlinger, Alexander Pichler, Gerhard Bachmaier, Stefan Ropele, Christian Enzinger, Michael Khalil

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    • P0157 - Serum neurofilament light-chain levels and long-term treatment outcomes in relapsing-remitting multiple sclerosis (RRMS) patients in the CombiRx trial (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Christina Eavis, Gary Cutter, Richard Rudick, Carl De Moor, Carol Singh, Elizabeth Fisher, Fred Lublin, Jerry Wolinsky, Henry McFarland, Steven Jacobson, Bernd Kieseier, Maria Naylor

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    • P0158 - Serum neurofilaments in Secondary Progressive Multiple Sclerosis: analysis from the MS-STAT trial (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Thomas Williams, Katherine Holdsworth, Jennifer Nicholas, Theodora Katsanouli, Henny Wellington, Amanda Heslegrave, Henrik Zetterberg, Chris Frost, Jeremy Chataway

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    • P0159 - Serum NfL predicts disability progression in MS in a six year longitudinal cohort study (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Timo Uphaus, Falk Steffen, Vinzenz Fleischer, Julia Loos, Frauke Zipp, Stefan Bittner

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    • P0160 - Serum NfL z-scores derived from a large healthy control group reflect different levels of treatment effect in a real-world setting (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Pascal Benkert, Sabine Schaedelin, Aleksandra Maceski, Giulio Disanto, Johanna Oechtering, Muhamed Barakovic, Annette Orleth, Dimitri Rey, Tim Sinnecker, Özgür Yaldizli, Reza Rahmanzadeh, Sabrina Zadic, Riccardo Galbusera, Ramona-Alexandra Todea, Alessandro Cagol, Lutz Achtnichts, Stefanie Aeschbacher, Andrew Chan, David Conen, Tobias Derfuss, Oliver Findling, Bettina Fischer-Barnicol, Kevin Hrusovsky, Harald Kropshofer, Patrice Lalive, Johanna Lieb, Johannes Lorscheider, Pietro Maggi, Christian Müller, Stefanie Müller, Yvonne Naegelin, Jorge Oksenberg, Caroline Pot, Renaud Du Pasquier, Ernst-Wilhelm Radue, Anke Salmen, Jochen Vehoff, Emmanuelle Waubant, Sven Wellmann, Heinz Wiendl, Jens Wuerfel, Chiara Zecca, Claudio Gobbi, Ludwig Kappos, Klaus Berger, Cristina Granziera, David Leppert, Jens Kuhle

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    • P0161 - Short-term evaluation of alemtuzumab to ocrelizumab switch in MS patients with disease activity after alemtuzumab: an Italian multicentric study. (View Presentation)

      Keyword: Clinical Outcome Measures

      Caterina Lapucci, Jessica Frau, Eleonora Cocco, Paola Cavalla, Marco Vercellino, Maria Petracca, Roberta Lanzillo, Paola Grossi, Maria Teresa Ferrò, Clara Guaschino, Mauro Zaffaroni, francesco Tazza, Giovanni Novi, Antonio Uccelli, Matilde Inglese

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    • P0162 - Single cell RNA-seq of MS CSF cells reveals a bias toward expanded CD8 T cells (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Grant Feuer, Jonah Vernejoul, Jerry Lin, Saud Sadiq

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    • P0163 - Smartphone keystroke dynamics are sensitive to changes in disease activity and clinical disability measures in multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Ka Hoo Lam, James Twose, Hannah McConchie, Giovanni Licitra, Bastiaan Moraal, Frederik Barkhof, Bernard Uitdehaag, Vincent De Groot, Joep Killestein

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    • P0164 - Smoking is associated with increased plasma neurofilament light levels in multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Ali Manouchehrinia, Hanna Larsson, Jesse Huang, Lars Alfredsson, Fredrik Piehl, Jens Kuhle, Tomas Olsson, Ingrid Kockum

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    • P0165 - Social Matters: Social support is linked to mental health, quality of life, and motor function in multiple sclerosis (View Presentation)

      Keyword: Clinical Outcome Measures

      Anne Kever, Korhan Buyukturkoglu, Claire Riley, Phillip De Jager, Victoria Leavitt

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    • P0166 - Sociodemographic features and disability in African-American and Caucasian patients with Multiple Sclerosis (View Presentation)

      Keyword: Clinical Outcome Measures

      Maria Petracca, Amgad Droby, Mohamed Mounir El Mendili, Swetha Paduri, Nicole Graziano, Natalie Saba, Arielle Falcone, Daniel Kurz, Claire Riley, Jonathan Howard, Sylvia Klineova, Fred Lublin, Matilde Inglese

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    • P0167 - Ten-Foot Tandem Walk: Detection of subtle gait changes and future fall risk in MS (View Presentation)

      Keyword: Clinical Outcome Measures

      Rachel Brandstadter, Robin Graney, James Sumowski

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    • P0168 - Test-retest reliability of the mini-BESTest in people with mild to moderate multiple sclerosis (View Presentation)

      Keyword: Clinical Outcome Measures

      Andreas Wallin, Maire Kierkegaard, Erika Franzén, Sverker Johansson

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    • P0169 - The association between spontaneous MxA mRNA level and disease activity in multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Eline Coerver, Laura Van Der Voort, Joep Killestein, E. Strijbis

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    • P0170 - The GNDS is suitable for changes in walking performance in progressive multiple sclerosis   (View Presentation)

      Keyword: Clinical Outcome Measures

      Charlotte Van 'T Hullenaar, Nynke Kalkers, Bernard Uitdehaag, Joep Killestein, E. Strijbis

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    • P0171 - The gut mycobiome in pediatric multiple sclerosis: establishing a bioinformatics pipeline (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Nelson Mok, Natalie Knox, Douglas L Arnold, Amit Bar-Or, Charles Bernstein, Jessica Forbes, Morag Graham, Janace Hart, Ruth Ann Marrie, Julia O’mahony, E. Ann Yeh, Feng Zhu, Gary Van Domselaar, Brenda Banwell, Emmanuelle Waubant, Helen Tremlett

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    • P0172 - The prognostic value of lipid-specific IgM oligoclonal bands versus IgM index in patients with a clinical isolated syndrome: a comparative study. (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Enric Monreal, Susana Sainz de la Maza, Jose Ignacio Fernandez-Velasco, Paulette Walo Delgado, Mercedes Espiño, Noelia Villarrubia, Ana Gómez López, Jaime Masjuan, Lucienne Costa-Frossard, Luisa María Villar

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    • P0173 - The serum levels of Interleukin 17 in patients with neuromyelitis optica spectrum disorder (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Tarlan Varzandi, Abolfazl Omidifar, Mina Torkamani, Nasim Rezaeimanesh, Razieh Kazemi, Mohammad Ali Sahraian, Abdorreza Naser Moghadasi, Zhila Maghbooli

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    • P0174 - TNFα and IL-6 levels in Relapsing-Remitting Multiple Sclerosis Patients on Dimethylfumarate: a Biomarker Study (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      William Baek, Song Zhai, Elizabeth Morrison

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    • P0175 - Towards optimized monitoring of serum neurofilament light chain in MS (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Tomas Uher, Jens Kuhle, Niels Bergsland, Jan Krasensky, Andrija Javor, Barbora Srpová, Christian Barro, Michael Dwyer, Michaela Tyblova, Pascal Benkert, David Leppert, Eva Havrdova, Manuela Vaneckova, Robert Zivadinov, Tomas Kalincik, Dana Horakova

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    • P0176 - Treatment and care management, clinical outcomes and mobility impairment in people with or without MS aged ≥ 50 years: observational 6-year analysis (View Presentation)

      Keyword: Clinical Outcome Measures

      Leorah Freeman, Ashlea Lucas, Jia Zhou, Brooke Hayward, Terrie Livingston

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    • P0177 - Treatment Persistency for Patients in a Phase 2 Long-Term Extension Study of Ponesimod (View Presentation)

      Keyword: Clinical Outcome Measures

      Alexander Keenan, Volker Breu, Hoa Le, Michele Cole, Brian Hennessy

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    • P0178 - Use of wearable biosensors to collect real-world patient activity data in two randomized phase 2 studies of elezanumab in multiple sclerosis (View Presentation)

      Keyword: Biosensors

      Kim Pfleeger, Adam Ziemann, Bruce Cree

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    • P0179 - Using NIH Toolbox Standing Balance Test to quantify subtle balance impairment in patients with multiple sclerosis (View Presentation)

      Keyword: Clinical Outcome Measures

      Giacomo Boffa, caterina Lapucci, francesco Tazza, Elisabetta Mancuso, elvira Sbragia, nicolò Bruschi, Maria Cellerino, Matilde Inglese

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    • P0180 - Utility of neurofilament light chain (NfL) and glial fibrillary acidic protein (GFAP) in tracking treatment response in PPMS patients (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      James Giarraputo, Stephanie Giamberardino, Stephanie Arvai, Christopher Eckstein, Sarah Maichle, L. Newby, Simon Gregory

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    • P0182 - Validation of the FeetMe® System versus GAITRite® to Assess Gait Characteristics in Patients with Multiple Sclerosis: Subpopulation analysis (View Presentation)

      Keyword: Clinical Outcome Measures

      Anabel Granja Domínguez, Anja Hochsprung, Susana Palao, Cristina Páramo, Aurora Alemán Rodríguez, Carmen Durán, Guillermo Navarro, Ana Venegas, Raúl Romero Sevilla, Maria José Moreno Jiménez, Guillermo Izquierdo

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    • P0183 - Wearable technologies: where can we focus on next in Multiple Sclerosis? (View Presentation)

      Keyword: Clinical Outcome Measures

      Sarah Alexander, Guy Peryer, Emma Gray, Frederik Barkhof, Jeremy Chataway

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    • P0184 - A novel approach to conducting Phase IV studies: The design of the global diroximel fumarate EXPERIENCE study initiative (View Presentation)

      Keyword: Clinical Trials

      Beatrix Bevernage, James Lewin, Jordan Messer, Shivani Kapadia, Irene Koulinska, Sylvia Luca, Miguel Rosales, Carl De Moor, Jason P. Mendoza, Catherine Miller

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    • P0185 - A phase II randomised controlled trial of a cognitive behavioral therapy intervention for depression in those newly diagnosed with MS (View Presentation)

      Keyword: Clinical Trials

      Litza Kiropoulos, Trevor Kilpatrick, Tomas Kalincik, Leonid Cherulov, Neil Shuey, Tissa Wijeratne

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    • P0186 - A Phase 1 study of BIIB091, a Bruton’s tyrosine kinase (BTK) inhibitor, in healthy adult participants: preliminary results (View Presentation)

      Keyword: Clinical Trials

      Matt Scaramozza, Million Arefayene, Xiaomei Peng, Mike Palte, Jeanelle Kam, Alison Graham, Katherine Riester, Alexander Coppell, Eris Bame, Michaël Mingueneau, Brian Hopkins, Shibeshih Belachew, Nathalie Franchimont

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    • P0187 - A prospective randomized open-label blinded endpoint multicenter non-inferiority study of oral cladribine and rituximab in Multiple Sclerosis (NOR-MS) (View Presentation)

      Keyword: Clinical Trials

      Gro Nygaard, Åslaug Lorentzen, Tone Hognestad, Cecilia Simonsen, Margitta Kampman, Heidi Flemmen, Kristin Wesnes, Alok Bhan, Stein Bjelland, Charlotte Natvig, Kristin Breivik, Kaj Blennow, Henrik Zetterberg, Lars Westlye, Elisabeth Celius, Marte Wendel-Haga, Marissa Leblanc, Johanna Gehin, Helle Stangeland, Tone Berge, Einar Høgestøl, Piotr Sowa, Hanne Harbo

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    • P0188 - A Tablet-Based Cognitive Battery to Assess Cognitive Function in People with MS: Sensitivity to Change in A Randomized Controlled Trial (View Presentation)

      Keyword: Clinical Trials

      Wan-Yu Hsu, William Rowles, Joaquin Anguera, Annika Anderson, Adam Gazzaley, Riley Bove

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    • P0189 - AQP4-IgG seronegative patient outcomes in the N-MOmentum trial of inebilizumab in neuromyelitis optica spectrum disorder (View Presentation)

      Keyword: Clinical Trials

      Ian Williams, Sean Pittock, Friedemann Paul, Romain Marignier, Ho Jin Kim, Jeffrey Bennett, Brian Weinshenker, Dean Wingerchuk, Ari Green, Kazuo Fujihara, Gary Cutter, Orhan Aktas, Hans Peter Hartung, Jorn Drappa, John Ratchford, Dewei She, Daniel Cimbora, Eliezer Katz, Bruce Cree

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    • P0190 - ASPIRE Study: Protocol for a double-blind RCT of aspirin for overheating during exercise in MS (View Presentation)

      Keyword: Clinical Trials

      Victoria Leavitt, Anne Kever, Katherine Nelson, Ines Aguerre, Claire Riley, Phillip De Jager, Amelia Boehme, Rebecca Straus Farber, Seth Levin, Nancy Lee, Joel Stein

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    • P0191 - Autologous Stem Cell Transplantation versus Alemtuzumab or Ocrelizumab in Relapsing Remitting Multiple Sclerosis (StarMS) (View Presentation)

      Keyword: Clinical Trials

      Jennifer Petrie, Basil Sharrack, John Snowden, Paolo Muraro

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    • P0192 - Benefit-risk of ofatumumab in treatment-naïve early relapsing multiple sclerosis patients (View Presentation)

      Keyword: Clinical Trials

      Jutta Gartner, Stephen Hauser, Amit Bar-Or, Xavier Montalban, Jeffrey Cohen, Anne H. Cross, Kumaran Deiva, Dieter A. Häring, Bingbing Li, Ratnakar Pingili, Krishnan Ramanathan, Wendy Su, Ludwig Kappos

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    • P0193 - BEST-MS: A standardized and prospective study comparing the efficacy of natalizumab versus fingolimod in active relapsing multiple sclerosis (View Presentation)

      Keyword: Clinical Trials

      Mikael Cohen, Lydiane Mondot, Florence Bucciarelli, Beatrice Pignolet, David Laplaud, Bruno Brochet, Gilles Defer, Patrick Vermersch, Marc Debouverie, Eric Berger, Pierre Labauge, Jerome De Seze, David Brassat, Christine Lebrun-Frenay

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    • P0194 - Cardiac Safety of Ponesimod in Relapsing Multiple Sclerosis in the Randomized, Active-Controlled, Double-Blind, Parallel-Group Phase 3 OPTIMUM Study (View Presentation)

      Keyword: Clinical Trials

      Till Sprenger, Andrea Vaclavkova, Michel Burcklen, Mark Freedman, Robert Fox, Eva Havrdová, Brian Hennessy, Verena Walter, Reinhard Hohlfeld, Fred Lublin, Xavier Montalban, Carlo Pozzilli, Tatiana Scherz, Philippe Linscheid, Magdalena Pirozek-Lawniczek, Hilke Kracker, A Camm, Ludwig Kappos

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    • P0195 - Characteristics of Therapeutic Sequences of Patients Enrolled in the PRO-MSACTIVE Study Evaluating Ocrelizumab in Active Relapsing Multiple Sclerosis (View Presentation)

      Keyword: Clinical Trials

      Christine Lebrun-Frenay, Sandra Vukusic, Pierre Labauge, Caroline Bensa, Bertrand Bourre, Eric Manchon, Paul-Henri Depoortere, Marie Lotz, R Niarra, David Laplaud, Isabelle Lawrence

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    • P0196 - Cladribine to halt deterioration in people with advanced multiple sclerosis (ChariotMS) (View Presentation)

      Keyword: Clinical Trials

      David Lieberman, Harpreet Mangat, Kimberley Allen-Philbey, David Baker, Frederik Barkhof, Siddharthan Chandran, Christine Chapman, Jeremy Chataway, Helen Ford, Gavin Giovannoni, Jeremy Hobart, Richard Hooper, Tahera Hussain, Neil Walker, David Macmanus, Borislava Mihaylova, Sue Pavitt, Klaus Schmierer

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    • P0197 - Clinical relapse rates in relapsing MS patients treated with the BTK inhibitor evobrutinib: results of an open-label extension to a Phase II study (View Presentation)

      Keyword: Clinical Trials

      Xavier Montalban, Douglas L Arnold, Martin Weber, Ivan Staikov, Karolina Piasecka-Stryczynska, Emily Martin, Matthew Mandel, Victor Ona, Fernando Dangond, Jerry Wolinsky

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    • P0198 - Comparative effectiveness of different DMT strategies in new onset RRMS; First results of the CombatMS trial (View Presentation)

      Keyword: Clinical Trials

      Suvi Virtanen, Fredrik Piehl, Thomas Frisell

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    • P0199 - Declining to participate in a randomised controlled trial of a cognitive occupation-based program for people with multiple sclerosis. (View Presentation)

      Keyword: Clinical Trials

      Anusha Moses, Christopher P. Dwyer, Robert Joyce, Dympna Casey, Sinéad M. Hynes

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    • P0200 - Diroximel Fumarate in Patients With Relapsing-Remitting Multiple Sclerosis: Interim Safety and Efficacy Results From the Phase 3 EVOLVE-MS-1 Study (View Presentation)

      Keyword: Clinical Trials

      Sibyl Wray, Barry Singer, Jelena Drulovic, Hailu Chen, Jerome Hanna, Jennifer Lyons, Florian Then Bergh, Donald Negroski, Shivani Kapadia

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    • P0201 - Disability improvement in relapsing-remitting multiple sclerosis patients receiving cladribine tablets, evaluated by expanded disability status scale (View Presentation)

      Keyword: Clinical Trials

      James Plested, Maria Pia Sormani, Gavin Giovannoni, Alessio Signori, Nektaria Alexandri

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    • P0202 - Durable efficacy of cladribine tablets: cumulative relapse incidence over 5 years in CLARITY and CLARITY Extension (View Presentation)

      Keyword: Clinical Trials

      Esther Dodge, Gavin Giovannoni, Kottil Rammohan, Thomas Leist, Patricia Coyle, Birgit Keller, Dominic Jack, Nektaria Alexandri

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    • P0203 - Effect of teriflunomide on MRI lesion activity across age groups in patients with relapsing multiple sclerosis from the TEMSO study (View Presentation)

      Keyword: Clinical Trials

      Cameron Duvall, Jiwon Oh, Jens Wuerfel, Bhupendra Khatri, Aaron Miller, Jihad Inshasi, Albert Saiz, Alex Lublin, Elizabeth Poole, Till Sprenger

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    • P0204 - Effect on disability measures and MSFC in patients with relapsing multiple sclerosis from the phase 3 ponesimod versus teriflunomide optimum study (View Presentation)

      Keyword: Clinical Trials

      shweta Pitre, Robert Fox, Ludwig Kappos, Michel Burcklen, Mark Freedman, Eva Havrdova, Brian Hennessy, Reinhard Hohlfeld, Fred Lublin, Xavier Montalban, Carlo Pozzilli, Tatiana Scherz, Philippe Linscheid, Lisa Ford, Magdalena Pirozek-Lawniczek, Hilke Kracker, Till Sprenger

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    • P0205 - Effects of Diroximel Fumarate on Brain Volume Change and Disability Progression in Adults With Relapsing-Remitting Multiple Sclerosis From EVOLVE-MS-1 (View Presentation)

      Keyword: Clinical Trials

      Douglas L Arnold, Jiwon Oh, Barry A. Singer, Hailu Chen, Jerome Hanna, Catherine Miller, Robert T. Naismith

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    • P0206 - Effects of nanocatalysis on CNS bioenergetic markers in patients treated with CNM-Au8: Interim results from two Phase 2 31Phosphorous imaging studies (View Presentation)

      Keyword: Clinical Trials

      Jimin Ren, Austin Rynders, Jacob Evan, Benjamin Greenberg, Richard Dewey, Jr., Karen Ho, Phd, Robert Glanzman, Md, Faan, Michael Hotchkin

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    • P0207 - Effects of Nurse Practitioner Care compared to Community Neurologist Care on Depression and Anxiety Levels in People with MS: a randomized trial (View Presentation)

      Keyword: Clinical Trials

      Penelope Smyth, Kaitlyn Watson, Karen Turpin, Ross Tsuyuki

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    • P0208 - Effects of Wahls Elimination and Swank Dietary Patterns on Multiple Sclerosis Related Fatigue, Quality of Life, Processing Speed and Waking Distance (View Presentation)

      Keyword: Clinical Trials

      Terry Wahls, Warren Darling, Karin Hoth, John Kamholz, Linda Rubenstein, Patrick Ten Eyck, Babita Bisht, Tyler Titcomb, Linda Snetselaar

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    • P0209 - Efficacy and safety of ofatumumab versus placebo in relapsing multiple sclerosis patients in Japan and Russia: Results from the Phase 2 APOLITOS study (View Presentation)

      Keyword: Clinical Trials

      Arshjyoti Singh, Jun-ichi Kira, Jin Nakahara, Denis V. Sazonov, Takayoshi Kurosawa, Isao Tsumiyama, Roman Willi, Martin Zalesak, Dieter A. Häring, Krishnan Ramanathan, Martin Merschhemke, Ratnakar Pingili, Takahiko Saida

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    • P0210 - Elezanumab in patients with different disease courses of multiple sclerosis: study design and baseline analysis from two phase 2 studies (View Presentation)

      Keyword: Clinical Trials

      Bruce Cree, Adam Ziemann, Kim Pfleeger, Brittany Schwefel, Annette Wundes, Mark Freedman, Samara Attalla

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    • P0211 - Examination of fenebrutinib, a highly selective BTKi, on disease progression of multiple sclerosis (View Presentation)

      Keyword: Clinical Trials

      Michelle Gheen, Stephen Hauser, Amit Bar-Or, Gordon Francis, Gavin Giovannoni, Ludwig Kappos, Jacqueline Nicholas, Jiwon Oh, Maria Pia Sormani, Sharon Stoll, Martin Weber, Aurelien Viaccoz, Victoria Levesque, Howard Mackey, Alexandra Goodyear

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    • P0212 - Ginseng as a possible candidate for fatigue management in neuromyelitis optica spectrum disorder: a double-blind randomized clinical trial (View Presentation)

      Keyword: Clinical Trials

      Sara Aslzadeh, Shaghayegh Shahmirzaei, Mohammad Ali Sahraian, Razieh sadat Kazemi Mozdabadi, Hossein Rezaei Aliabadi, Mohammad Reza Gheini, Nasim Rezaeimanesh, Sharareh Eskandarieh, Fazeleh Majidi, Abdorreza Naser Moghadasi

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    • P0213 - Immune cell profiles and clinical and safety outcomes with fingolimod in the 12 month FLUENT study of patients with relapsing multiple sclerosis (View Presentation)

      Keyword: Clinical Trials

      Holly Hunter, Yang Mao-Draayer, Jeffrey Cohen, Amit Bar-Or, May Han, Barry Singer, Scott Kolodny, Chelsea Elam, Xiangyi Meng, Marina Ziehn, Bruce Cree

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    • P0214 - Improved GI tolerability with diroximel fumarate Is associated with clinically meaningful benefits on QoL compared to dimethyl fumarate in EVOLVE-MS-2 (View Presentation)

      Keyword: Clinical Trials

      Annette Wundes, Sibyl Wray, Elzbieta Jasinska, Tjalf Ziemssen, Hailu Chen, Jerome Hanna, Jennifer Lyons, Jordan Messer, Robert T. Naismith

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    • P0215 - Long-term efficacy and safety of ponesimod: Results from randomized phase II core and extension studies in relapsing‑remitting multiple sclerosis (View Presentation)

      Keyword: Clinical Trials

      Mark Freedman, Carlo Pozzilli, Eva Kubala Havrdová, Patricia Coyle, Alexandre Lemle, Michel Burcklen, Anna Larbalestier, Brian Hennessy, Tatiana Scherz, Andrea Vaclavkova, Tomas Olsson

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    • P0216 - Long-term reduction of relapse rate and 48-week confirmed disability progression after 6.5 years of ocrelizumab treatment in patients with RMS (View Presentation)

      Keyword: Clinical Trials

      Amber O'Connor, Gavin Giovannoni, Ludwig Kappos, Jerome De Seze, Stephen Hauser, James Overell, Harold Koendgen, H-M Schneble, Kalpesh Prajapati, Qing Wang, Jerry Wolinsky

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    • P0217 - Long-term safety and efficacy of ozanimod in relapsing multiple sclerosis in DAYBREAK: an open-label extension study of ozanimod phase 1−3 trials (View Presentation)

      Keyword: Clinical Trials

      Johanna Moore, Krzysztof Selmaj, Lawrence Steinman, Giancarlo Comi, Amit Bar-Or, Douglas Arnold, Hans Peter Hartung, Xavier Montalban, Eva Havrdova, James Sheffield, Tianlei Chen, Neil Minton, Diego Silva, Ludwig Kappos, Jeffrey Cohen, Bruce Cree

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    • P0218 - Long-term safety, compliance, and effectiveness of ofatumumab in patients with relapsing multiple sclerosis: ALITHIOS Phase 3b study (View Presentation)

      Keyword: Clinical Trials

      Edward J. Fox, Lori Mayer, Angela Aungst, Linda Mancione, Nicola Rennie, Aurore Roustan, Dee Stoneman, Wendy Su, Ayan Das Gupta, Martin Zalesak, Marina O. Ziehn, Derrick Robertson, Jeffrey Cohen

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    • P0219 - Ocrelizumab Phase IIIb efficacy from CASTING: 2-year NEDA (MRI re-baselined) subgroup rates in RRMS patients with a suboptimal response to prior DMTs (View Presentation)

      Keyword: Clinical Trials

      Amber O'Connor, Heinz Wiendl, Giancarlo Comi, Celia Oreja-Guevara, Aksel Siva, Bart Van Wijmeersch, Jens Wuerfel, Regine Buffels, Karen Kadner, T Kuenzel, Patrick Vermersch

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    • P0220 - Ocrelizumab Phase IIIb efficacy: 1-year NEDA rates (with MRI re-baselining) from the ENSEMBLE study in early-stage relapsing-remitting MS patients (View Presentation)

      Keyword: Clinical Trials

      Kiran Tailor, Hans Peter Hartung, Thomas Berger, Robert Bermel, Bruno Brochet, Trygve Holmøy, R Karabudak, Joep Killestein, C Nos, Francesco Patti, Amy Perrin Ross, Timothy Vollmer, Jens Wuerfel, Regine Buffels, T Kuenzel, Mark Freedman

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    • P0221 - Ocrelizumab treatment in patients with RRMS who had a suboptimal response with one or more prior disease-modifying therapies: CHORDS 2-year results (View Presentation)

      Keyword: Clinical Trials

      Michelle Gheen, Bianca Weinstock-Guttman, Rob Bermel, Gary Cutter, Mark Freedman, Thomas Leist, Jinglan Pei, Diedre Kile, Bruno Musch, Anthony Reder, Jerry Wolinsky

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    • P0222 - OLIKOS study design: exploring maintained ofatumumab efficacy in relapsing MS patients who transition from intravenous anti-CD20 therapy (View Presentation)

      Keyword: Clinical Trials

      Holly Hunter, Benjamin Greenberg, Enrique Alvarez, John Foley, Roland Henry, Joel Brown, Elizabeth Camacho, Xiangyi Meng, Marina Ziehn, Brandon Brown, Le Hanh Hua

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    • P0223 - “Personalized extended interval dosing of natalizumab in relapsing remitting multiple sclerosis – a prospective multicenter trial in The Netherlands" (View Presentation)

      Keyword: Clinical Trials

      Alyssa Toorop, Theo Rispens, Bernard Uitdehaag, Joep Killestein, Zoé Van Kempen

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    • P0224 - Pharmacokinetic-Pharmacodynamic Models of Lymphocyte Count and Heart Rate Following Ponesimod Dosing in a Phase 2 Study in Multiple Sclerosis Patients (View Presentation)

      Keyword: Clinical Trials

      Italo Poggesi, Belén Valenzuela Jiménez, Sivi Ouwerkerk-Mahadevan, Alexandre Lemle, Michel Burcklen, Anna Larbalestier, Brian Hennessy, Tatiana Scherz, Andrea Vaclavkova, Quentin Leirens, Juan Jose Perez-Ruixo

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    • P0225 - Phase 3 Study Results Assessing the Efficacy and Safety of ADS-5102 (Amantadine) Extended Release Capsules in MS Patients with Walking Impairment (View Presentation)

      Keyword: Clinical Trials

      Jeffrey Cohen, Michelle Cameron, Myla Goldman, Andrew Goodman, Aaron Miller, Anne Rollins, Reed Johnson, Lily Llorens, Rajiv Patni, Robert Elfont

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    • P0226 - Phase I study of ATA188, an off-the-shelf, allogeneic Epstein-Barr virus-targeted T-cell immunotherapy for progressive forms of multiple sclerosis (View Presentation)

      Keyword: Clinical Trials

      Claire Jones, M P Pender, S J Hodgkinson, S Broadley, J Lindsey, Z A Ioannides, B Bagert, R Khanna, C Smith, L Gamelin, W Ye, J Willmer, Amit Bar-Or

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    • P0227 - Phase I, multicenter, two-part study of ATA188, an open-label, dose-escalation and double-blind, placebo-controlled dose-expansion study (View Presentation)

      Keyword: Clinical Trials

      Claire Jones, Amit Bar-Or, L Gamelin, W Ye, J Willmer, B T Aftab, P Foubert, M P Pender

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    • P0228 - Post-treatment recovery of lymphocyte subsets in healthy volunteers treated with ozanimod (View Presentation)

      Keyword: Clinical Trials

      Johanna Moore, Sarah Harris, Jonathan Tran, Peijin Zhang, Harry Southworth

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    • P0229 - Quiescent MRI activity in neuromyelitis optica spectrum disorder: results from the N-MOmentum randomized placebo-controlled trial (View Presentation)

      Keyword: Clinical Trials

      Ian Williams, Friedemann Paul, Dean Wingerchuk, Brian Weinshenker, Jeffrey Bennett, Ho Jin Kim, Sean Pittock, Kazuo Fujihara, Gary Cutter, Romain Marignier, Orhan Aktas, Hans Peter Hartung, Ari Green, Jorn Drappa, Michael Smith, William Rees, John Ratchford, Dewei She, Daniel Cimbora, Diana Stefani-Hunyady, Eliezer Katz, Bruce Cree

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    • P0230 - Rationale and design of two Phase IIIb studies of ocrelizumab at higher than the approved dose in patients with RMS and PPMS (View Presentation)

      Keyword: Clinical Trials

      Amber O'Connor, Stephen Hauser, Amit Bar-Or, Gordon Francis, Ludwig Kappos, Jacqueline Nicholas, Jiwon Oh, Maria Pia Sormani, Sharon Stoll, Martin Weber, Kocho Fitovski, Monika Garas, Heidemarie Kletzl, Harold Koendgen, Marianna Manfrini, Fabian Model, H-M Schneble, Sean Yiu, Gavin Giovannoni

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    • P0231 - Reduced grey matter atrophy in patients with relapsing multiple sclerosis treated with cladribine tablets (View Presentation)

      Keyword: Clinical Trials

      Esther Dodge, Marco Battaglini, Maria Pia Sormani, Ludovico Luchetti, Giordano Gentile, Rosa Cortese, Nektaria Alexandri, Nicola De Stefano

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    • P0232 - Safety and efficacy of dimethyl fumarate in patients with primary progressive multiple sclerosis: A double-blind, randomized phase 2 trial (View Presentation)

      Keyword: Clinical Trials

      Helene Højsgaard Chow

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    • P0233 - Safety and tolerability of conversion to siponimod in patients with relapsing multiple sclerosis: interim results of the EXCHANGE study (View Presentation)

      Keyword: Clinical Trials

      Holly Hunter, Amit Bar-Or, Bianca Weinstock-Guttman, Yang Mao-Draayer, Gina Cox, Linda-Ali Cruz, Xiangyi Meng, Wendy Su, Stanley Cohan

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    • P0234 - Safety experience with extended exposure to ofatumumab in patients with relapsing multiple sclerosis from Phase 2 and 3 clinical trials (View Presentation)

      Keyword: Clinical Trials

      Arshjyoti Singh, Anne H. Cross, Edward Fox, Jérôme De Seze, Amit Bar-Or, Heinz Wiendl, Ayan Das Gupta, Dieter A. Häring, Valentine Jehl, Cecile Kerloeguen, Mohammad Gufran, Ratnakar Pingili, Wendy Su, Martin Zalesak, Stephen Hauser, Ludwig Kappos

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    • P0235 - Safety of the Bruton’s tyrosine kinase inhibitor evobrutinib in relapsing multiple sclerosis during an open-label extension to a phase II study (View Presentation)

      Keyword: Clinical Trials

      Xavier Montalban, Douglas L Arnold, Martin Weber, Ivan Staikov, Karolina Piasecka-Stryczynska, Emily Martin, Matthew Mandel, Victor Ona, Yulia Zima, Davorka Tomic, Jerry Wolinsky, Fernando Dangond

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    • P0236 - Serum immunoglobulin levels and infection risk in the Phase 3 trials of ofatumumab in relapsing multiple sclerosis (View Presentation)

      Keyword: Clinical Trials

      Heinz Wiendl, Jérôme De Seze, Amit Bar-Or, Jorge Correale, Anne H. Cross, Ludwig Kappos, Krzysztof Selmaj, Ayan Das Gupta, Dieter A. Haering, Valentine Jehl, Cecile Kerloeguen, Ratnakar Pingili, Wendy Su, Roseanne Sullivan, Martin Zalesak, Stephen Hauser

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    • P0237 - Sustained reduction in 48-week confirmed disability progression in patients with PPMS treated with ocrelizumab in the ORATORIO OLE: 7-year follow-up (View Presentation)

      Keyword: Clinical Trials

      Amber O'Connor, Jerry Wolinsky, Patrick Vermersch, Hans Peter Hartung, Robert T. Naismith, Laura Airas, Karine Coutant, Harold Koendgen, H-M Schneble, James Overell, Annette Sauter, Kalpesh Prajapati, Ludwig Kappos

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    • P0238 - Sustained reduction of disability and cognitive decline with long-term siponimod treatment in patients with active SPMS: EXPAND data up to 5 years (View Presentation)

      Keyword: Clinical Trials

      Gavin Giovannoni, Ludwig Kappos, Robert Fox, Patrick Vermersch, Bruce A.C. Cree, Ralph Benedict, Amit Bar-Or, Nicolas Rouyrre, Daniela Piani-Meier, Thomas Hach, Shannon Ritter, Ajay Kilaru, Frank Dahlke, Göril Karlsson, Ralf Gold

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    • P0239 - Temelimab for prevention of neurodegeneration: preclinical safety profile and design of the ProTEct-MS (temelimab following rituximab in RMS) study (View Presentation)

      Keyword: Clinical Trials

      Fredrik Piehl, Gabrielle Kornmann, Bruce Cree, Hans Peter Hartung, Cristina Granziera, Tobias Granberg, Jens Kuhle, Bénédicte Buffet, Nathalie Berthuy, Justyna Leja-Jarblad, Gunilla Törnqvist, Julie Medina, Patrick Küry, Thomas Rückle, David Leppert

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    • P0240 - Therapeutic Decisions in MS Care: An International Study comparing Clinical Judgement vs. Information from Artificial Intelligence-Based Models (View Presentation)

      Keyword: Clinical Trials

      Gustavo Saposnik, Xavier Montalban, Maria Pia Amato, Óscar Fernández, Fernando Caceres, Ho Jin Kim, Andreia Costa, Veronica Popescu, Eva Kubala Havrdová, Melinda Magyari, Heinz Wiendl, Tomas Kalincik, Elisabeth Celius, Maria Terzaghi, Robert Bermel, Fei Zuo, Jiwon Oh

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    • P0241 - Top-line Results of EMPhASIS, a Phase 2 Clinical Trial of Vidofludimus Calcium (IMU-838) in Relapsing-Remitting Multiple Sclerosis (View Presentation)

      Keyword: Clinical Trials

      Robert Fox, Heinz Wiendl, Nicola De Stefano, Johann Sellner, Andreas Mühler

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    • P0242 - Treating minority patients with multiple sclerosis: development of the CHIMES trial (View Presentation)

      Keyword: Clinical Trials

      Michelle Gheen, Mitzi Williams, Lilyana Amezcua, Tim Vartanian, Gregory Wu, Nancy Monson, Evanthia Bernitsas, Chris Harp, Xiaoming Jia, Jinglan Pei, Ashish Kothari, Anthony Reder

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    • P0243 - VISIONARY-MS: A Phase 2 clinical trial of catalytic gold nanocrystals, CNM-Au8, for the treatment of chronic optic neuropathy (View Presentation)

      Keyword: Clinical Trials

      Robert Glanzman, Md, Faan, Heidi Beadnall Mbbs Fracp, Michael Hotchkin, Alexander Klistorner, Michael Barnett, Md, Robert Sergott, Austin Rynders, Karen Ho, Phd, Mark Mortenson

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    • P0244 - A simple two-step test based on CSF flow cytometry helps to discriminate MS from other inflammatory and non-inflammatory neurologic disorders (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Ilya Kister, Itay Lotan, Asya Wallach, Tamar Bacon, Gary Cutter, Arnaldo Arbini

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    • P0245 - An unusual mimic of progression in Multiple Sclerosis patients (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Gary Alvarez Bravo, Lluís Ramió I Torrentà, René Robles Cedeño, Ester Quintana, Jordi Gich, Marina González

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    • P0246 - Clinical relevance of Kappa Free Light Chain index to evaluate intrathecal IgG synthesis: prospective study compared to oligoclobal bands (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Tifanie Alberto, Jean-David Pekar, Julie Petit, Susanna Schraen, Brigitte Onraed, Helene Zephir

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    • P0247 - Comparison of the 2017 and 2010 revisions of the McDonald criteria in patients with cis suggestive of MS: a multicentre MAGNIMS study (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Massimo Filippi, Paolo Preziosa, Alessandro Meani, Alex Rovira, Sarlota Mesaros, Olga Ciccarelli, Jette Lautrup Frederiksen, Christian Enzinger, Frederik Barkhof, Claudio Gasperini, Enrico Fainardi, Wallace Brownlee, Jelena Drulovic, Xavier Montalban, Stig Cramer, Michael Kalil, Marloes Hagens, Serena Ruggieri, Gloria Dalla Costa, Vittorio Martinelli, Katherine Miszkiel, Mar Tintore, Giancarlo Comi, Iris Dekker, Bernard Uitdehaag, Jovana Ivanović, Maria Pia Amato, Maria A. Rocca

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    • P0248 - Consensus guidelines for the timely detection and diagnosis of disease progression in multiple sclerosis patients (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Celia Oreja-Guevara, Bonaventura Casanova-Estruch, Juan Antonio García-Merino, Lucienne Costa-Frossard, Dionisio Fernández-Uría, José Ramón Ara, José Prieto, Carmen Calles, Migule Ángel Hernandez, Jordi Río, Carmen Durán, Guillermo Izquierdo, Sara Eichau, Alfredo Rodríguez-Antigüedad, María José Moreno, David Fernández, José Meca-Lallana

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    • P0249 - Demyelinating events following initiation of anti-TNFɑ therapy in the British Society for Rheumatology Biologics Registry in Rheumatoid Arthritis (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Thomas Taylor, james Galloway, Rebecca Adam, Kimme Hyrich, Ruth Dobson

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    • P0250 - Diagnostic Dilemma in a case of suspected Anti-phospholipid Syndrome (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Nate Lightfoot, MOira Scaperotti, Ashley Streseman, Laxman Bahroo, Sean Whelton

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    • P0251 - Early factors associated with later conversion to multiple sclerosis in patients presenting with isolated myelitis (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Olwen Murphy, Loulwah Mukharesh, Andrea Salazar-Camelo, Carlos Pardo, Scott Newsome

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    • P0252 - Evolving diagnosis and treatment of secondary progressive multiple sclerosis in the United States (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Robert T. Naismith, Virginia Schobel

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    • P0253 - Gaps in characterization of bladder dysfunction in clinical care and research (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Arpita Gopal, Valerie Block, Jeffrey Gelfand, Ari Green, Chu-Yueh Guo, Anne Suskind, Riley Bove

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    • P0254 - Healthcare Professionals (HCPs) categorisation of active and non-active Secondary Progressive Multiple Sclerosis (SPMS) patients (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Joanna White, Sandra Teoh, Simone Gabriele, Joseph Vindici

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    • P0255 - Improvement during the last decades in the time of diagnosis but not in the time of starting DMD in MS patients in Argentina (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Juan Rojas, Liliana Patrucco, Agustin Papolla, Edgardo Cristiano

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    • P0256 - Inclusion of optic nerve assessed by visual evoked potentials in dissemination in space criteria for the diagnosis of Multiple Sclerosis (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Sofia Delgado, Ângela Timóteo, Joana Dionísio, Ana Rodrigues, Ana Arraiolos, Pedro Neves, André Rêgo, José Vale, Vasco Salgado, Mariana Santos

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    • P0257 - Infratentorial MS relapse presenting as hemifacial continuous myokymia (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Manuel Salavisa, Pedro Pires, Filipa Serrazina, Ana Sofia Correia

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    • P0258 - MS Progression Discussion Tool (MSProDiscuss™) Usability and Usefulness Assessment in Clinical Practice in Chile. (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Claudia Cárcamo, Ethel Ciampi, Ramiro Fernández, Lorna Galleguillos, Sabrina Oporto, Jacqueline Scherpenisse, Mario Rivera, Adolfo Araya, Maureen Hitschfeld

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    • P0259 - Multiple Sclerosis, variant Marburg, an uncommon form: about a case.  (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      María Martínez Zarco, Isabel Pellicer Espinosa, Eliot Gómez López, Ester Marín Conesa, José Marín Marín

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    • P0260 - Obinutuzumab use complicated by progressive multifocal leukoencephalopathy: a case report. (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Gaëtane Turine, Frédéric London

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    • P0261 - Paramagnetic rim lesions are specific to multiple sclerosis: an international multicenter 3T MRI study (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Pietro Maggi, Pascal Sati, Govind Nair, Irene Cortese, Steven Jacobson, Bryan Smith, Avindra Nath, Joan Ohayon, Vincent Van Pesch, Gaetano Perrotta, Caroline Pot, Marie Theaudin, Vittorio Martinelli, Roberta Scotti, Tianxia Wu, Renaud Du Pasquier, Peter Calabresi, Massimo Filippi, Daniel Reich, Martina Absinta

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    • P0262 - Searching for Fabry disease in previously diagnosed CIS and defined MS patients: a cohort study. (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Marzia Fronza, Elisa Sunda, Lorena Lorefice, Giancarlo Coghe, Giuseppe Fenu, Luigina Musu, Gabriella Spinicci, Eleonora Cocco, Jessica Frau

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    • P0263 - Serum neurofilament predicts clinical progression and increases diagnostic accuracy in patients with early multiple sclerosis (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Stefan Bittner, Falk Steffen, Timo Uphaus, Muthuraman Muthuraman, Vinzenz Fleischer, Anke Salmen, Felix Luessi, Achim Berthele, Luisa Klotz, Sven Meuth, Antonios Bayas, Friedemann Paul, Hans Peter Hartung, Ralf Linker, Christoph Heesen, Martin Stangel, Brigitte Wildemann, Florian Then Bergh, Björn Tackenberg, Tania Kuempfel, Frank Weber, Uwe Zettl, Ulf Ziemann, Hayrettin Tumani, Sergiu Groppa, Mark Mühlau, Carsten Lukas, Bernhard Hemmer, Heinz Wiendl, Ralf Gold, Frauke Zipp

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    • P0264 - Simultaneous bilateral optic neuropathy and myelitis revealing paraneoplastic neurological syndrome associated with multiple onconeuronal antibodies (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Timothée Carette, Nicolas Mulquin, Vincent Van Pesch, Frédéric London

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    • P0265 - Sjogren-larsson Syndrome:Another Differential Diagnosis of Multiple Sclerosis in Imaging of White Matter Diseases. (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Shadi Zamanian, Ebrahim Pourakbar

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    • P0266 - Susac syndrome: A rare cause of encephalopathy (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Jessica Decker, Mini Singh, Jacqueline Koshorek

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    • P0267 - The Contribute of CSF Free Ligh Chain assay in the diagnosis of Multiple Sclerosis and other Neurological Diseases in an Italian multicentric study (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Gaetano Bernardi, Ilaria Crespi, Tiziana Biagioli, Teresa De Michele, Paola Malpassi

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    • P0268 - Time interval between disease onset and MS diagnosis during the last decades in Latin America (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Juan Rojas, Edgar Carnero Contentti, Paula Henestroza, Susana Giachello, Jorge Correale

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    • P0269 - Vitamin B12 deficiency or MS!? Vitamin B12 deficiency can mimic Multiple Sclerosis. (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Ebrahim Pourakbar , Shadi Zamanian

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    • P0270 - 2-Chlorodeoxyadenosine (Cladribine) preferentially inhibits the biological activity of microglia cells (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Florencia Aybar, Maria Perez, Silvina Marcora, Maria Samman, Juana Pasquini, Jorge Correale

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    • P0271 - A Case of Drug Induced Myocarditis Associated With the Administration of Alemtuzumab (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Miriam Ross, Kelly Lawrence, Adnan Subei

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    • P0272 - A case series of late onset neutropenia following Ocrelizumab therapy in Multiple Sclerosis (MS) (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      maryam Talaei, Kate Petheram, Gillian Ingram, Anand Trip, Owen Pearson

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    • P0273 - A multicentre, real-life study on the risk of lymphopenia and infections discloses a favourable safety profile of cladribine in MS patients. (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Monica Margoni, Pietro Annovazzi, Luca Prosperini, Rocco Capuano, Antonio Gallo, Jessica Frau, Eleonora Cocco, Agostino Nozzolillo, Lucia Moiola, Marco Capobianco, Mauro Zaffaroni, Paola Perini

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    • P0274 - A Swedish post-market surveillance study of the long-term effectiveness and safety of alemtuzumab (IMSE 3) for patients treated for at least 36 months (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Åsa Leandersson, Stina Kågström, Linda Forsberg, Jan Hillert, Petra Nilsson, Charlotte Dahle, Anders Svenningsson, Jan Lycke, Anne-Marie Landtblom, Joachim Burman, Claes Martin, Peter Sundström, Martin Gunnarsson, Fredrik Piehl, Tomas Olsson

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    • P0275 - A Swedish Post-Market Surveillance Study of the Long-Term Effectiveness and Safety of Teriflunomid (IMSE 4) for Patients Treated at least 36 Months (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Linda Forsberg, Stina Kågström, Åsa Leandersson, Jan Hillert, Petra Nilsson, Charlotte Dahle, Anders Svenningsson, Jan Lycke, Anne-Marie Landtblom, Joachim Burman, Claes Martin, Martin Gunnarsson, Fredrik Piehl, Tomas Olsson

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    • P0276 - A Swedish Post-Market Surveillance Study: Long-Term Effectiveness and Safety of Cladribine Tablets (IMSE 10) for Patients Treated at least 12 Months (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Linda Forsberg, Stina Kågström, Åsa Leandersson, Jan Hillert, Petra Nilsson, Charlotte Dahle, Anders Svenningsson, Jan Lycke, Anne-Marie Landtblom, Joachim Burman, Claes Martin, Peter Sundström, Martin Gunnarsson, Fredrik Piehl, Tomas Olsson

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    • P0277 - A Swedish Post-Market Surveillance Study: Long-Term Effectiveness and Safety of Dimethyl Fumarate (IMSE 5) for Patients Treated at least 36 Months (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Linda Forsberg, Stina Kågström, Åsa Leandersson, Anders Berglund, Jan Hillert, Petra Nilsson, Charlotte Dahle, Anders Svenningsson, Jan Lycke, Anne-Marie Landtblom, Joachim Burman, Claes Martin, Peter Sundström, Martin Gunnarsson, Fredrik Piehl, Tomas Olsson

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    • P0278 - A Systematic Review and Meta-analyses of Pregnancy and Fetal Outcomes in Women with Multiple Sclerosis. IMI2 ConcePTION (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Sandra Lopez-Leon, Yvonne Geissbuehler, Meritxell Sabidó, Moise Turkson, Charlotte Wahlich, Joan Morris

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    • P0279 - ACAPELLA: B-cell Reconstitution in Ocrelizumab-Treated Patients (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      India Stribling, Hannah Geils, Joshua Katz, Ellen Lathi, Elizabeth Douglas, Andrew Bouley

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    • P0280 - ACAPELLA: Hypogammaglobulinemia and JCV Status in Ocrelizumab-Treated Patients, Year Two Data (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Hannah Geils, India Stribling, Joshua Katz, Ellen Lathi, Elizabeth Douglas, Andrew Bouley

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    • P0281 - ACAPELLA: Real-World Experience with Ocrelizumab: An Observational Study Evaluating Safety in Patients with Relapsing and Progressive MS, Year Three (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Hannah Geils, India Stribling, Joshua Katz, Ellen Lathi, Elizabeth Douglas, Andrew Bouley

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    • P0282 - Advancing antigen-specific T cell therapy for progressive multifocal leukoencephalopathy (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Sasha Gupta, Pawel Muranski, Irene Cortese, Michael Wilson

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    • P0283 - Adverse event profile differences between rituximab and ocrelizumab: Findings from the FDA Adverse Event Reporting Database (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Natalia Gonzalez Caldito, Afsaneh Shirani, Amber Salter, Olaf Stuve

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    • P0284 - Age-related efficacy of cladribine tablets in patients with relapsing-remitting MS in the CLARITY Extension study (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Mark Freedman, Gabriel Pardo, Nicola De Stefano, Julie Aldridge, Yann Hyvert, Andrew Galazka, Caroline Lemieux, Gavin Giovannoni

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    • P0285 - Alemtuzumab depletion failure and neutralizing anti-drug antibodies: a case report and call for monitoring (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Kathleen Munger, Angray Kang, David Baker, Andrew Goodman, Lawrence Samkoff

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    • P0286 - Alemtuzumab following natalizumab: a multicentric Italian real-world experience (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Simona Malucchi, Marco Capobianco, Maria Malentacchi, Marianna Lo Re, Francesca Sperli, Rugiada Bottero, Alessandra Oggero, Francesca Rinaldi, Paola Perini, Marta Radaelli, Alice Laroni, Antonio Gallo, Antonio Bertolotto

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  • PO02 - On-Demand ePosters P0287-P0572

    • Type: Poster
    • Presentations: 282
    Presented on: 9/11/2020, 08:00
    View Posters

    • P0287 - Alemtuzumab induces changes in the innate immune system in patients with relapsing-remitting multiple sclerosis (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Anne Ladwig, Julia Suh, Finja Schweitzer, Philip Roeth, Gina Remke, Clemens Warnke, Michael Schroeter, Elena Izquierdo-Alvarez, Eckhard Bonmann, Gereon R. Fink, Christian Pallasch, Helmar Lehmann

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    • P0288 - Analysis of CD3 T lymphocyte count in patients under treatment with Ocrelizumab regarding development of infections (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Alicia Gonzalez-Martinez, Virginia Meca-Lallana, Clara Aguirre, Carolina Díaz, Jose Vivancos

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    • P0289 - Analysis of first line therapy criteria responses in a cohort of 1300 Relapsing Remitting MS patients. (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Pierre Labauge



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    • P0290 - Anti-CD20 therapy interferes with the immune response to the Hepatitis B virus vaccine in MS patients (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Susana Otero-Romero, Simón Cárdenas-Robledo, Marta Rodríguez, Sonia Uriona, Ariadna Rando, Anka Vidal-Jordana, Juliana Esperalba, Eva Del Amo, José Rodrigo-Pendás, Magda Campins, Xavier Martínez, Mar Tintore, Xavier Montalban

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    • P0291 - Association of Headache with B-cell Targeted Therapies in Multiple Sclerosis patients. (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Theodoros Mavridis, Nikolaos Papagiannakis, Marianthi Breza, Achilleas Laskaratos, Dimos Mitsikostas

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    • P0292 - Associations between treatment satisfaction, medication beliefs, and adherence to DMT in MS patients: Saudi Tertiary Care Center Experience (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Rola Alarieh

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    • P0294 - Autoinmunity secondary to alemtuzumab in clinical practice: 5 years of RWE (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Julio Dotor García-Soto, Rocío López Ruiz, Sara Eichau Madueño, María Ruiz De Arcos, Juan luis Ruiz-Peña, Maria Dolores Páramo Camino, Guillermo Navarro Mascarell

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    • P0295 - Autologous Hematopoietic Stem Cell Transplantation in Multiple Sclerosis (aHSCT-in-MS): The Zurich Experience 24 Months after Approval (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Ilijas Jelcic, Antonia Müller, Marc Hilty, Nathan Wolfensberger, Panos Stathopoulos, Josefine Ruder, Andrea Thesenvitz, Katharina Ritter, Adrian Bachofner, Magdalena Foege, Andreas Lutterotti, Urs Schanz, Roland Martin

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    • P0296 - Automated extraction of multiple sclerosis treatment timelines (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Mary Davis, Megan Rimmasch, Kaylia Reynolds, Jeremy Beales

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    • P0297 - Autonomic nervous system abnormalities may predict cardiovascular changes after initiation of siponimod in the treatment of SPMS (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Luka Crnosija, Anamari Junakovic, Ivan Adamec, Barbara Barun, Tereza Gabelic, Magdalena Krbot Skoric, Mario Habek

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    • P0298 - Azathioprine as a disease-modifying therapy for multiple sclerosis.  Experience of department of Neurology: HASSAN II UHC of Fez; Morocco (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Roukya Benkhadra, siham Bouchal, naima Chtaou, aouatif Elmidaoui, zouhair Souirti, mohammed Belahsen

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    • P0299 - Balo’s concentric sclerosis successfully treated with Alemtuzumab (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      David Paling, Todd Hardy, Ajaz Khan, Jessica Redgrave, Nigel Hoggard, Stuart Coley, Richard Dyde, Ronan O Malley, Zeid Yasiry

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    • P0300 - Baseline features in DISCOntinuation of disease modifying therapies in Multiple Sclerosis (DISCOMS) (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Rebecca Seale, Gary Cutter, Robert Fox, Ilya Kister, Aaron Miller, Charity Morgan, Stefan Sillau, John Corboy

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    • P0301 - Beyond pivotal trials inclusion criteria: real world clinical profile of multiple sclerosis patients under disease modifying treatment in Argentina. (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Andres Barboza, Juan Rojas, María Gaitán, Susana Liwacki, Carlos Vrech, Agustin Papolla, Jimena Miguez, Liliana Patrucco, Jorge Correale, Mariano Marrodan, Marcela Fiol, laura Negrotto, Celica Ysrraelit, Edgardo Cristiano, Adriana Carrá, Anibal Chertcoff, Judith Steinberg, alejandra Martinez, Celeste Curbelo, Leila Cohen, Ricardo Alonso, orlando Garcea, Cecilia Pita, Berenice Silva, Geraldine Luetic, Norma Deri, Maria Eugenia Balbuena, Veronica Tkachuk, Edgar Carnero Contentti, Pablo Lopez, Juan Pettinicchi, alejandro Caride, Marcos Burgos, Felisa Leguizamon, Eduardo Knorre, Raúl Piedrabuena, Pedro Nofal, Gabriel Volman, AMelia Alvez Pinheiro, Javier Hryb, Darío Tavolini, Patricio Blaya, Luciano Recchia, Carolina Mainella, Matías Kohler, Eduardo Kohler, Jorge Blanche, Santiago Tizio, María Saladino, Fernando Caceres, Nora Fernandez Liguori, Luciana Lazaro, Emanuel Silva, Gisela Zanga, Marcela Parada Marcilla, Maria Eugenia Fracaro, Fátima Pagani Cassará, Guido Vazquez, Vladimiro Sinay, Gustavo Sgrilli, Pablo Divi, Miguel Jacobo, Edgardo Reich, Lorena Cabrera, Maria Menichini, Mariano Coppola, Ivan Martos, Juan Viglione, Gustavo Jose, Santiago Bestoso, Ruben Manzi, Diego Giunta, Maria Doldan, Marina Alonso Serena

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    • P0302 - Bruton tyrosine kinase inhibitor suppresses disease progression in Thieler’s Murine Enchephalomyelitis Virus mouse model of multiple sclerosis (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Suyog Pol, Ravendra Dhanraj, Robert Zivadinov

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    • P0303 - Calculated steroid dose needed for multiple scleroses relapses (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Judit Gili-Kovacs, Rober Hoepner, Anke Salmen, Maud Bagnoud, Ralf Gold, Andrew Chan, Myriam Briner

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    • P0304 - Can the induction of thyroid autoimmune antibodies after alemtuzumab treatment predict secondary autoimmune thyroid disorder? (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Sofia Sandgren, Lenka Novakova, Markus Axelsson, Firoozeh Amirbeagi, Ingrid Kockum, Tomas Olsson, Clas Malmeström, Jan Lycke

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    • P0305 - Can We Predict Ocrelizumab Super Responder Status in Relapsing Remitting Multiple Sclerosis Patients? (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Nicolas Edgar, Tammy Hoyt, John Foley

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    • P0306 - Cardiovascular monitoring during alemtuzumab infusion in Multiple Sclerosis patients (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Riccardo Giossi, Eugenia Tomas Roldan, Massimo Costanza, Carlo Antozzi, Rita Frangiamore, Valentina Torri Clerici, Paolo Confalonieri, Alessandra Tozzo, Renato Mantegazza, Laura Brambilla

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    • P0307 - Changes in immune blood cells in patients on teriflunomide treatment (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Irene Gómez_estévez, Judit Díaz-Díaz, Celia Oreja-Guevara

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    • P0308 - Changing patterns of first line and first switch ocrelizumab use in the United States: Analysis of subtype, gender, age, and disability (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Patricia Coyle, Meg Stabb, Virginia Schobel

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    • P0309 - Cladribine is a safe and effective treatment for highly active relapsing-remitting multiple sclerosis (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Thomas Suslak, Niall Macdougall, Lesley Murray

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    • P0310 - Cladribine tablets in patients with RRMS and active SPMS after suboptimal response to prior DMD (MASTER-2 and CLICK-MS): initial baseline demographics (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Augusto Miravalle, Joshua Katz, Derrick Robertson, Brooke Hayward, John Walsh, Danielle Harlow, Lori Lebson, Jacob Sloane, Ann Bass, Edward Fox

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    • P0311 - Decoding Bruton’s tyrosine kinase signalling in neuroinflammation (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Lauren Glendenning, Ross Gruber, Michael Dufault, Nathalie Chretien, Jonathan Proto, Mindy Zhang, Michael Lamorte, Evis Havari, Timothy Turner, Anthony Chomyk, Emilie Christie, Bruce Trapp, Dimitry Ofengeim

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    • P0312 - Differential effects of dimethyl fumarate, monomethyl fumarate and cannabidiol in the activation of transcription factor Nrf2 in neurons and microglia (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Alicia Sánchez-Sanz, María José Coronado-Albi, Ruth García-Hernández, Julia Sabín-Muñoz, Ofir Rodríguez-De La Fuente, Juan Antonio García-Merino, Antonio José Sánchez-López

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    • P0313 - Dimethyl fumarate-induced changes in lymphocyte subpopulations could identify "NEDA" patients (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Silvia Presas-Rodríguez, Aina Teniente-Serra, Ares Selles-Rius, María José Mansilla, Bibiana Quirant-Sánchez, Eva Martínez-Cáceres, Cristina Ramo-Tello

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    • P0314 - Dimethyl fumarate-induced lymphocyte count drop is related to clinical effectiveness in relapsing-remitting multiple sclerosis (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Elena Tsantes, Erica Curti, Diana Ferraro, Alessandra Lugaresi, Eleonora Baldi, Sara Montepietra, Paolo Immovilli, Anna Maria Simone, Luca Mancinelli, Silvia Strumia, Francesca Vitetta, Matteo Foschi, Caterina Ferri, Cecilia Ferrarini, Patrizia Sola, Franco Granella

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    • P0315 - Disease modifying therapies in patients with aggressive MS (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Firas Fneish, David Ellenberger, Niklas Frahm, Alexander Stahmann, Paulus Rommer, Uwe Zettl

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    • P0316 - Dose-dependent tolerability of intravenous and subcutaneous ofatumumab in clinical studies (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Amit Bar-Or, Agnes Annette Schubert-Tennigkeit, Nicole Mairon, Cecile Kerloeguen, Mohammad Gufran, Shima Shaikh, Ayan Das Gupta, Eswara Gunisetti, Gisbert Weckbecker, Wendy Su, Krishnan Ramanathan, Ratnakar Pingili

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    • P0317 - Dual mode of action of siponimod in secondary progressive multiple sclerosis: A hypothesis based on the relevance of pharmacological properties (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Marc Bigaud, Frank Dahlke, Thomas Hach, Daniela Piani-Meier, Ralf Gold

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    • P0318 - Early monitoring of B cells on ocrelizumab may help to identify those at risk of adverse effects (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Rachel Dorsey-Campbell, Chandni Radia, Joe Hill, Teresa Felongco, Dionisio Delacruz, Victoria Singh-Curry, Ashwini Nandoskar, Antonio Scalfari, Omar Malik, Richard Nicholas

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    • P0319 - Early Real-World Safety, Tolerability, and Efficacy of Cladribine Tablets: A Single Center Experience (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Julie Bain, Jiwon Oh, Ashley Jones, Daniel Selchen, Sarah Overholt, Melanie Guenette

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    • P0320 - Effect of age on effectiveness and discontinuation of subcutaneous interferon beta-1a, and healthcare utilization, in patients with multiple sclerosis (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      James Plested, Meritxell Sabidó, Arthur Allignol, Kurt Marhardt, Patrick Vermersch, Emmanuelle Boutmy

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    • P0321 - Effect of anti-CD20 antibody-induced B-cell depletion on the susceptibility to Streptococcus pneumoniae infections (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Giuseppe Ercoli, Elisa Ramos-Sevillano, Milda Folkmanaite, Maria Leandro, Geraldine Cambridge, Gisbert Weckbecker, Jeremy Brown

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    • P0322 - Effect of anti-CD20 antibody-mediated B-cell depletion on susceptibility to a Pneumocystis infection in mice (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Guixiang Dai, Gisbert Weckbecker, Jay K. Kolls

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    • P0323 - Effect of neutralizing antibodies on pharmacodynamic biomarkers of subcutaneous interferon β-1a in REFLEX and REFLEXION (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      James Plested, Mark Freedman, Kristina Holmberg, Markus Fluck, Yann Hyvert, Sofia Stinchi, Vittorio D’urso, Fernando Dangond

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    • P0324 - Effect of ocrelizumab treatment in peripheral blood leukocyte subsets of Primary Progressive Multiple Sclerosis patients (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Jose Ignacio Fernandez-Velasco, Jens Kuhle, Enric Monreal, Virginia Meca-Lallana, José Meca-Lallana, Guillermo Izquierdo, Francisco Gascón Giménez, Susana Sainz de la Maza, Paulette Walo Delgado, Aleksandra Maceski, Eulalia Rodríguez-Martin, Ernesto Roldán, Noelia Villarrubia, Albert Saiz, Yolanda Blanco, Pedro Sánchez, Ester Carreón Guarnizo, Yolanda Aladro, LUIS Brieva, Cristina Íñiguez, Inés González-Suárez, Luis Rodríguez De Antonio, Jaime Masjuan, Lucienne Costa-Frossard, Luisa María Villar

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    • P0325 - Effect of ozanimod on proportions of leukocyte subsets in patients with relapsing multiple sclerosis (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Johanna Moore, Sarah Harris, Jonathan Tran, Harry Southworth, Collin Spencer, Bruce Cree, Scott Zamvil

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    • P0326 - Effect of Teriflunomide on Epstein-Barr Virus Shedding in Relapsing-Remitting Multiple Sclerosis Patients: Outcomes From a Real-world Cohort Study (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Cameron Duvall, Julian Gold, David Holden, John Parratt, Con Yiannikas, Raghib Ahmad, Gavin Giovannoni

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    • P0327 - Effectiveness and safety profile of the Natalizumab extended interval dosing in a Spanish cohort (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Lucienne Costa-Frossard, Susana Sainz de la Maza, Enric Monreal, Ana Gómez López, Jose Ignacio Fernandez-Velasco, Paulette Walo Delgado, Mercedes Espiño, Noelia Villarrubia, Jaime Masjuan, Luisa María Villar

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    • P0328 - Effectiveness of cladribine in multiple sclerosis – clinical experience of two tertiary centers (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Ariana Barros, Mónica Santos, João Sequeira, Marisa Brum, Joana Parra, Lia Leitão, Filipa Ladeira, João Ferreira, João De Sá, Carlos Capela

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    • P0329 - Effects of adrenocorticotropic hormone on melanocortin receptors, regulatory immune cells, and MRI in MS (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Quentin Howlett-Prieto, Anthony Reder, Xuan Feng, Timothy Houston, Adil Javed

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    • P0330 - Effects of cladribine on proliferation, survival and cytokine release of human astrocytes (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Herena Eixarch, Laura Calvo-Barreiro, Nicolás Fissolo, Ursula Boschert, Manuel Comabella, Xavier Montalban, Carmen Espejo

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    • P0331 - Efficacy and safety in patients treated with Natalizumab for at least 10 years - Real-world data from a Swedish national surveillance study (IMSE 1) (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Stina Kågström, Åsa Leandersson, Linda Forsberg, Anders Berglund, Jan Hillert, Petra Nilsson, Charlotte Dahle, Anders Svenningsson, Jan Lycke, Anne-Marie Landtblom, Joachim Burman, Peter Sundström, Claes Martin, Martin Gunnarsson, Fredrik Piehl, Tomas Olsson

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    • P0332 - Evaluating the Efficacy and Safety of Transitioning Patients from Natalizumab to Ocrelizumab (OCTAVE) (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Kyle Smoot, Tiffany Gervasi-Follmar, Chiayi Chen, Pavle Repovic, Hui-Juan Zhang, Crystal Moreno, Stanley Cohan

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    • P0333 - Evaluating the mode of action of kappa opioid receptor agonists in the treatment of multiple sclerosis (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Lisa Denny, Katharina Robichon, Nicola Templeton, Thomas Prisinzano, Bronwyn Kivell, Anne La Flamme



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    • P0334 - Evobrutinib, a highly selective BTK inhibitor, prevents antigen-activation of B cells and ameliorates experimental autoimmune encephalomyelitis (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Sebastian Torke, Roxanne Pretzsch, Darius Häusler, Roland Grenningloh, Ursula Boschert, Wolfgang Brück, Martin Weber

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    • P0335 - Exploring the rate, persistence and associations of lymphopaenia in people with multiple sclerosis treated with dimethyl fumarate. (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Thomas Flamini, James Harley, Jennie Truman, Tom Button

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    • P0336 - Exposure to Natalizumab during pregnancy: A French national retrospective study (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Pauline Bouchard, Sarah Demortière, Fabien Rollot, Aurélie Ruet, Mathilde Deloire, Marc Debouverie, Jérôme De Seze, Thibault Moreau, Jonathan Ciron, Olivier Casez, Sandra Vukusic, Romain Casey, Cécile Dulau, Jean-Christophe Ouallet, Katy-Kim Kounkou, Audrey Rico, Adil Maarouf, Clémence Boutière, Bertrand Audoin, Jean Pelletier, Bruno Brochet

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    • P0337 - Extensive healthy donor age/gender adjustments and propensity score matching reveal physiology of multiple sclerosis through immunophenotyping (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Paavali Hannikainen, Peter Kosa, Christopher Barbour, Samuel Wachamo, Bibiana Bielekova

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    • P0338 - Fenebrutinib, a noncovalent, highly selective, long residence time investigational Btk inhibitor for the treatment of MS (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Michelle Gheen, Adam Johnson, Chris Harp, Jiajie Yu, Alexandra Goodyear, James Crawford

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    • P0339 - Fingolimod immune suppression does not inhibit long-term efficacy of AAV gene immunotherapy   (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Addelynn Sagadevan, Isabelle Cote, Geoffrey Keeler, Cristina Gaddie, Brad Hoffman

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    • P0340 - High-dimensional immune profiling of dimethyl fumarate and ocrelizumab in multiple sclerosis (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Yinan Zhang, Brian Lee, Hui Xie, Jonathan Rockoff, Rachel Brandstadter, Seunghee Kim-Schulze, Fred Lublin, Achillefs Ntranos

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    • P0341 - Human papilloma virus related anal carcinoma during treatment with natalizumab: A case report. (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Mathias Kneffel, Ju Won Chae



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    • P0342 - Immune reconstitution inflammatory syndrome in a patient treated with alemtuzumab a few years earlier (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Anna Jamroz-Wiśniewska, Urszula Chyrchel, Ewa Belniak, Marzena Janczarek, Halina Bartosik-Psujek, Konrad Rejdak

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    • P0343 - Inhibition of drug transporter breast cancer resistance protein has no effect on the pharmacokinetics of major active metabolites of ozanimod (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Johanna Moore, Peijin Zhang, Atalanta Ghosh, Mark Thomas, Xiaomin Wang, Maria Palmisano, Jonathan Tran

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    • P0344 - Injectable versus oral first-line disease-modifying therapies: results from Italian MS register (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Emanuele D'Amico, Aurora Zanghì, Marzia Romeo, Eleonora Cocco, Giorgia Teresa Maniscalco, vincenzo Bresciamorra, Damiano Paolicelli, Giovanna De Luca, Simonetta Galgani, Maria Pia Amato, Giuseppe Salemi, Matilde Inglese, paolo agostino Confalonieri, Giacomo Lus, Antonio Gallo, Marika Vianello, Marco Onofrj, Carlo Pozzilli, Massimo Filippi, Maria Trojano, Francesco Patti

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    • P0345 - Interim Analysis of Pregnancy Outcomes Following Exposure to Dimethyl Fumarate in a Prospective International Registry (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Kerstin Hellwig, David Rog, Christopher McGuigan, Oksana Mokliatchouk, FIlipe Branco, Xiaomei Peng, Cynthia Jones

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    • P0346 - Is the gut a relevant reservoir for persistent JCPyV infection? (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Finja Schweitzer, Anne Ladwig, Sarah Laurent, Michael Schroeter, Susan Goelz, Ulrike Wieland, Steffi Silling, Clemens Warnke

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    • P0347 - Late-onset neutropenia in a multiple sclerosis patient after first dose ocrelizumab switched from rituximab (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Michael Auer, Gabriel Bsteh, Harald Hegen, Sebastian Wurth, Anne Zinganell, Thomas Berger, Florian Deisenhammer, Franziska Di Pauli

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    • P0348 - Lipoic acid modulates inflammatory responses of monocytes and monocyte-derived macrophages via cyclic-AMP and Nrf2-dependent mechanisms. (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Sarah Fiedler, Sonemany Salinthone

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    • P0349 - Long term effectiveness and safety of teriflunomide in Relapsing Remitting Multiple Sclerosis, and improvement in quality of life: Tericare study (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      José María Prieto González, JOSE Meca, ANA Caminero, JAVIER Olaskoaga, VENTURA Casanova, Nicolás Herrera Varo, Miguel Llaneza, LUIS Berenguer, ROSA Casademont, SUSANA Martinez

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    • P0350 - Long-term drug persistence in natalizumab JCV negative patients in the Swedish post-market surveillance study IMSE-1 (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Anders Berglund, Stina Kågström, Fredrik Piehl, Tomas Olsson

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    • P0351 - Lymphocyte reconstitution following discontinuation of Dimethyl fumarate (DMF) due to lymphopenia in the Swedish post-market surveillance study IMSE-5 (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Anders Berglund, Linda Forsberg, Fredrik Piehl, Tomas Olsson

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    • P0352 - Lymphocyte Subtypes Repopulation Pattern and Secondary Autoimmunity in patients with RRMS treated with Alemtuzumab in a Real World setting (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      NIKOLAOS Fakas, Victor Kotzamanis, Alexandra Akrivaki, Theodoros Mavridis, Dimitra Tzavella, Sokratis Triantafyllou, Georgios Papadopoulos, Panagiotis Apostolopoulos

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    • P0353 - Lymphopenia in patients treated with dimethyl fumarate. Risk factors and clinical significance. Experience in daily clinical practice (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Gabriel Valero López, Maria Teresa Alba Isasi, Ester Carreón Guarnizo, Rocio Hernandez Clares, Maria Canovas Iniesta, Moisés Morales De La Prida, Francisca Iniesta Martinez, Ana Morales Ortiz, José Meca-Lallana

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    • P0354 - Management of infectious risk in multiple sclerosis: implication for screening, prophylaxis and therapies (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Maria Antonella Zingaropoli, Valentina Perri, Patrizia Pasculli, Matteo Tartaglia, Sebastiano Crisafulli, Chiara Merluzzo, Viola Baione, Flavia Pauri, Marta Altieri, Marco Frontoni, Antonella Conte, Claudio Maria Mastroianni, Maria Rosa Ciardi

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    • P0355 - Management of lymphopenia associated with dimethylfumarate and fingolimod (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Brina Bharkhada, Aoife Shields

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    • P0356 - MOG-derived Imotopes, a new class of MHC-II epitope modification, inducing cytolytic CD4 T-cells as novel immunotherapy in multiple sclerosis          (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      David Walgraffe, Isabelle Ote, Roxana Roohi Ahangarani, Milos Erak, Marcelle Van Mechelen, Antoon Van Oosterhout, Luc Vander Elst, Vincent Carlier

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    • P0357 - Mouse astrocytes exhibit agonist-induced functional S1P1 receptor antagonism (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Nada Ben Yakoub, Tatjana Uffelmann, Sarah Tisserand, Marc Bigaud

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    • P0358 - Multiple Sclerosis with anti-N-methyl-D-aspartate receptor immunoglobulin G antibodies. An unusual relationship. (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Moisés Morales De La Prida, Maria Canovas Iniesta, Gabriel Valero López, José López Sánchez, Ester Carreón Guarnizo, Rocio Hernandez Clares, Francisca Iniesta Martinez, Judith Jiménez Veiga, Ana Morales Ortiz, José Meca-Lallana

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    • P0359 - Natalizumab and eosinophilia: epidemiological characteristics and clinical associations (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Lara Diem, Robert Hoepner, Maud Bagnoud, Anke Salmen, Andrew Chan, Christoph Friedli

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    • P0360 - No difference in radiologic outcomes for natalizumab patients on extended interval dosing compared with standard interval dosing in MS PATHS (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Christina Eavis, Lana Zhovtis-Ryerson, Robert T. Naismith, Lauren Krupp, Leigh Charvet, Ray Su, Elizabeth Fisher, Carl De Moor, James Williams, Nolan Campbell

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    • P0361 - Non-thyroid secondary autoimmune diseases after alemtuzumab treatment: real-world data from a nationwide prospective observational cohort in Sweden. (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Sofia Sandgren, Lenka Novakova, Markus Axelsson, Firoozeh Amirbeagi, Ingrid Kockum, Tomas Olsson, Clas Malmeström, Jan Lycke

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    • P0362 - Novel treatment approach for fingolimod-associated progressive multifocal leukoencephalopathy in a patient with relapsing remitting multiple sclerosis (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Andrew Barritt, Esther Das, Nadine Morley, Matthew Seymour, Romi Saha, Jaime Vera, Sriram Vundavalli, Sabina Dizdarevic, Richard Nicholas, Joseph Berger, Leonora Fisniku

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    • P0363 - Ocrelizumab as exit strategy from natalizumab: results from a clinical series (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Elena Tsantes, Erica Curti, Alessia Fiore, Veronica Bazzurri, Franco Granella

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    • P0364 - Ocrelizumab real-world safety and effectiveness in the two years of treatment in multiple sclerosis. (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Brandi Vollmer, Anthony Declusin, Kavita Nair, Stefan Sillau, John Corboy, Timothy Vollmer, Enrique Alvarez

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    • P0365 - Ocrelizumab treatment in patients with progressive multiple sclerosis: a single-center real-world experience (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Maria Cellerino, Giacomo Boffa, caterina Lapucci, elvira Sbragia, nicolò Bruschi, Elisabetta Mancuso, francesco Tazza, Ilaria Poirè, Alice Laroni, Elisabetta Capello, Antonio Uccelli, Giovanni Novi, Matilde Inglese

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    • P0366 - Ocrelizumab-Therapy associated Lymphopenia is linked to age in patients with Multiple Sclerosis in a Single-Centre Retrospective Cohort Study. (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Johannes Plenge, Thorben Beyer, Frank Leypoldt, Klarissa Hanja Stürner

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    • P0367 - Online Medical Simulation Identifies Rationales for the Use and Avoidance of DMTs for Highly Active MS Among Neurologists (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Thomas Finnegan, Allison Armagan, Martin Warters, Patricia Coyle

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    • P0368 - Persistent severe lymphopenia of at least one-year duration after dimethyl fumarate discontinuation: three case reports (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Natalia Gonzalez Caldito, Shirley O'Leary, Olaf Stuve

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    • P0369 - Posibble Risk Factors in Fingolimod Rebound Syndrome (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Cansu Goncuoglu, Cansu Ayvacioglu Cagan, Melike Cakan, Nazire Pinar Acar Ozen, Aygin Bayraktar-Ekincioglu, Aslı Tuncer, Rana Karabudak

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    • P0370 - Post-approval safety of subcutaneous interferon β-1a in the treatment of multiple sclerosis, with particular reference to respiratory viral infections (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      James Plested, Mark Freedman, Hans Guehring, Zuzana Murgasova, Dominic Jack

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    • P0371 - Practice improvement by retrospective analysis of changes in lymphocyte levels in patients with multiple sclerosis on dimethyl fumarate. (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Maria-Elizabeth Baeva, Philip Baev, Jill Nelson, Anna Kazimirchik, Galina Vorobeychik

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    • P0372 - Predictors of  Therapeutic Adherence in Multiple Sclerosis  in Argentina   (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Estefania Drzewiscki, Gisela Zanga, Diego Caruso, Paula Tagliani, Maria Esnaola Y Rojas

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    • P0373 - Profile of multiple sclerosis patients on treatment with ocrelizumab and socio-economic impact of the disease (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Ivan Barbov, Tatjana Boskova, Igor Kuzmanovski

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    • P0374 - Progressive MS patients of older age on ocrelizumab: real-world experience at Columbia University Irving Medical Center (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Samantha Epstein, Kathryn Fong, Phillip De Jager, Claire Riley, Libby Levine, Wendy Vargas, Rebecca Farber

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    • P0375 - Quantifying the risk of disease reactivation after DMT discontinuation – the VIAADISC score (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Gabriel Bsteh, Harald Hegen, Katharina Riedl, Patrick Altmann, Michael Auer, Klaus Berek, Franziska Di Pauli, Rainer Ehling, Barbara Kornek, Tobias Monschein, Walter Rinner, Christiane Schmied, Sebastian Wurth, Anne Zinganell, Gudrun Zulehner, Tobias Zrzavy, Florian Deisenhammer, Paulus Rommer, Fritz Leutmezer, Thomas Berger

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    • P0376 - RAM-589.555 favors neuroprotective/anti-inflammatory profile of CNS-resident glial cells in acute relapse EAE affected mice (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Rina Ilona Zilkha-Falb, Tatyana Rachutin-Zalogin, Lakota Kleaver, Michael Gurevich, Anat Achiron

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    • P0377 - Real world experience with cladribine: patient profile, efficacy and safety. (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Julio Dotor García-Soto, Rocío López Ruiz, Sara Eichau Madueño, María Ruiz De Arcos, Juan luis Ruiz-Peña, Maria Dolores Páramo Camino, Guillermo Navarro Mascarell

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    • P0378 - Real World Experience with Ocrelizumab in patiens with Relapsing-Remitting Multiple Sclerosis (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Rocío López Ruiz, Julio Dotor García-Soto, Juan Diego Guerra Hiraldo, Juan luis Ruiz-Peña, Maria Dolores Páramo Camino, María Ruiz De Arcos, Guillermo Navarro Mascarell, Sara Eichau Madueño

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    • P0379 - Real World Experience with Ocrelizumab in patients with Primary Progressive Multiple Sclerosis (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Rocío López Ruiz, Julio Dotor García-Soto, Juan Diego Guerra Hiraldo, Juan luis Ruiz-Peña, Maria Dolores Páramo Camino, María Ruiz De Arcos, Guillermo Navarro Mascarell, Sara Eichau Madueño

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    • P0380 - Real-world data of peginterferon beta-1a from a Swedish national post-marketing surveillance study (IMSE 6) – effectiveness and safety profile (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Stina Kågström, Åsa Leandersson, Linda Forsberg, Anders Berglund, Jan Hillert, Petra Nilsson, Charlotte Dahle, Anders Svenningsson, Jan Lycke, Anne-Marie Landtblom, Joachim Burman, Claes Martin, Peter Sundström, Martin Gunnarsson, Fredrik Piehl, Tomas Olsson

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    • P0381 - Reduced sphingosine kinase gene expression in SPMS vs. RRMS astrocytes revealed by single-nucleus RNA-seq (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Yasuyuki Kihara, Yunjiao Zhu, Deepa Jonnalagadda, William Romanow, Carter Palmer, Benjamin Siddoway, Richard Rivera, Ranjan Dutta, Bruce Trapp, Jerold Chun

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    • P0382 - Reduction in CUA MRI lesions in the first 6 months of cladribine tablets treatment for highly active relapsing multiple sclerosis: MAGNIFY-MS study (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Esther Dodge, Nicola De Stefano, Frederik Barkhof, Xavier Montalban, Anat Achiron, Tobias Derfuss, Andrew Chan, Suzanne Hodgkinson, Alexandre Prat, Letizia Leocani, Klaus Schmierer, Finn Sellebjerg, Patrick Vermersch, Heinz Wiendl, Birgit Keller, Sanjeev Roy

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    • P0383 - Resistance of CD11c+ B cells to anti-CD20 depletion with treatment initiation and early preferential repopulation of anti-inflammatory B cells in MS (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Koji Shinoda, Rui Li, Ayman Rezk, Amit Bar-Or

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    • P0384 - Risk Factors for Developing Lymphopenia and Hypogammaglobulinemia in anti-CD20 Treated Patients with Multiple Sclerosis (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Brandi Vollmer, Timothy Vollmer, John Corboy, Enrique Alvarez

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    • P0385 - Risk factors for ocrelizumab infusion reaction in a rural Appalachian population (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Eric Seachrist, Shitiz Sriwastava, Valerie Casuccio, Melanie Ward, Erica Blackwell, Ashley Petrone

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    • P0386 - Safety and Effectiveness of Dimethyl Fumarate Maintained Over 5 Years in Multiple Sclerosis Patients Treated in Routine Medical Practice (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      katherine Ayling-Rouse, Krupa Pandey, Kathryn Giles, Konstantin Balashov, Richard Macdonell, Jörg Windsheimer, Annette Okai, Mikel Martinez, Oksana Mokliatchouk, Becky Parks, Shivani Kapadia, Cynthia Jones

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    • P0387 - Safety and tolerability of cladribine in multiple sclerosis – clinical experience of two tertiary centers (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Mónica Santos, Ariana Barros, João Sequeira, Marisa Brum, Joana Parra, Lia Leitão, Filipa Ladeira, João Ferreira, Carlos Capela, João De Sá

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    • P0388 - Safety of dimethyl fumarate for multiple sclerosis: A systematic review and meta-analysis (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Geoffrey Liang, Julia Chai, Huah Shin Ng, Helen Tremlett

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    • P0389 - Safety of ocrelizumab in multiple sclerosis: updated analysis in patients with relapsing and primary progressive multiple sclerosis (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Kiran Tailor, Stephen Hauser, Ludwig Kappos, Xavier Montalban, C Chognot, Licinio Craveiro, Ashish Pradhan, Kalpesh Prajapati, Jerry Wolinsky

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    • P0390 - Seroconversion rate following HBV vaccination in clinical practice: the role of immunosenescence and concomitant DMT treatment (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Patrícia Faustino, Maria Coutinho, Lia Leitão, Carlos Capela, Marisa Brum, Joana Parra, João Sequeira, Ariana Barros, Cristina Araújo, Ana Sousa, Filipa Ladeira

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    • P0391 - Severe neutropenia after cladribine first cycle in a patient with Multiple Sclerosis (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Clara Aguirre, Virginia Meca-Lallana, Beatriz Del Río, Jose Vivancos

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    • P0392 - Shorter infusion time of ocrelizumab: results from the ENSEMBLE PLUS study in patients with relapsing-remitting multiple sclerosis (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Kiran Tailor, Bruno Brochet, Thomas Berger, Robert Bermel, Mark Freedman, Hans Peter Hartung, Trygve Holmøy, Joep Killestein, Amy Perrin Ross, Regine Buffels, Monika Garas, Karen Kadner, H-M Schneble, Qing Wang, C Nos

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    • P0393 - Similar clinical outcomes for natalizumab patients switching to every-6-week dosing versus remaining on every-4-week dosing in real-world practice (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Christina Eavis, Helmut Butzkueven, Ludwig Kappos, Tim Spelman, Maria Trojano, Heinz Wiendl, Ray Su, Robert Hyde, Stephanie Licata, Pei-Ran Ho, Nolan Campbell

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    • P0394 - Siponimod treatment leads to a dose-dependent reduction of EAE severity associated with downregulation of microglial activity. (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Leila Husseini, Anastasia Geladaris, Marlene Steinleitner, Katja Grondey, Julian Koch, Darius Häusler, Martin Weber

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    • P0395 - Species variation in sphingosine 1-phosphate receptor subtype 5 affects response to ozanimod in preclinical models of multiple sclerosis (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Johanna Moore, Julie Selkirk, Grace Yan, Nathan Ching, Shameek Biswas, Kevin Dines, Stephanie Smith, Carlos Lopez, Iliana Ruiz, Richard Hargreaves

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    • P0396 - Sustained and rapid B-cell depletion with ofatumumab: Population pharmacokinetic B-cell modeling in relapsing MS patients (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Gordon Graham, Joseph Kahn, Marina Savelieva, Huixin Yu, Ratnakar Pingili, Roman Willi, Krishnan Ramanathan, Olivier David, Dieter A. Haering, Morten Bagger

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    • P0397 - Switches to immune-reconstitution therapies in Europe and the United States: Analyses from annual retrospective patient chart audits (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Shiv Saidha, Meg Stabb, Nicholas Robinson, Virginia Schobel

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    • P0398 - Switching from natalizumab to ocrelizumab in patients with relapsing-remitting multiple sclerosis. (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Zoë Van Lierop, Alyssa Toorop, Eline Willemse, E. Strijbis, Nynke Kalkers, Bastiaan Moraal, Frederik Barkhof, Charlotte Teunissen, Joep Killestein, Zoé Van Kempen

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    • P0399 - Switching from ocrelizumab to cladribine: real world data (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Daniel O'Neill, Meena Sharma, Beatriz Gonzales, Meg Vandenheuval, Benjamin Tse, Suzanne Hodgkinson

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    • P0400 - Switching to Ocrelizumab from other second line treatments in relapsing-remitting Multiple Sclerosis: a single Center cohort (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Maria Barbara Pasanisi, Marco Vercellino, Valentina Schillaci, Chiara Bosa, Anastasia Alteno, Gianfranco Costantini, Adriano Chiò, Paola Cavalla

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    • P0401 - Switching disease modifying treatment in relapsing multiple sclerosis: Delphi consensus of the Demyelinating Group of the Spanish Society of Neurology (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      LUIS Brieva

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    • P0402 - Targeting monocyte migration for treatment of MS: Human ex-vivo proof-of-concept for Anti-MOSPD2 mAbs in patients with RR and progressive MS (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Naama Dym, Yaniv Salem, Arnon Karni, Ifat Vigiser, Keren Regev, Pinhas Kafri, Oshrat Propheta-Meiran, Niva Yacov, Eyal Breitbart, Itzhak Mendel

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    • P0403 - T-bet+ B-cell development in MS: Association with Bruton’s Tyrosine Kinase activity and targeting by evobrutinib (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Liza Rijvers, Marie José Melief, Jamie Van Langelaar, Annet Wierenga-Wolf, S Marieke Van Ham, Ursula Boschert, Roland Grenningloh, Joost Smolders, Marvin Van Luijn

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    • P0404 - The Bruton’s tyrosine kinase inhibitor evobrutinib ameliorates meningeal inflammation in experimental autoimmune encephalomyelitis (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Sol Kim, Ursula Boschert, Roland Grenningloh, Pavan Bhargava

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    • P0405 - The consequences of switching from Gilenya to generics for Fingolimod (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Leslie Menendez, Michael Osherov, Zeev Nitsan, Nurit Hovel, Ron Milo

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    • P0406 - The effect of cladribine upon naïve and activated CD4+ T regulatory cells in MS patients. (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Daniel O'Neill, N Verma, R Al-Atiyah, Meena Sharma, G Tran, Bruce Hall, Suzanne Hodgkinson

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    • P0407 - The Impact of Ocrelizumab on Immunoglobulin Levels and the Risk of Infection. (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Kyle Smoot, Crystal Moreno, Tamela Stuchiner, Chiayi Chen, Stanley Cohan

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    • P0408 - Therapeutic Plasma Exchange in MS relapses: long term outcome (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Mariano Marrodan, Santiago Crema, Lucas Alessandro, Adrian Rubstein, Jorge Correale, Maria Ysrraelit

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    • P0409 - Treatment Failure in patients with multiple sclerosis initiating frequently used first line therapies (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Devon Conway, Carrie Hersh, Mengru Wang, Fei Yang, Chinmay Deshpande

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    • P0410 - Treatment with ocrelizumab during Sars-Cov2 pandemic: efficacy and safety outcomes (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Francesco Tazza, caterina Lapucci, Giacomo Boffa, Maria Cellerino, elvira Sbragia, nicolò Bruschi, Giovanni Novi, Simona Minguzzi, Marta Traversa, Ilaria Poirè, Alice Laroni, Elisabetta Capello, Matilde Inglese

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    • P0411 - Treatment-emergent adverse events occurring early in the treatment course of cladribine tablets in two phase 3 trials in multiple sclerosis (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Jiwon Oh, Bryan Walker, Gavin Giovannoni, Dominic Jack, Fernando Dangond, Axel Nolting, Julie Aldridge, Lori Lebson, Thomas Leist

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    • P0412 - Treatment-induced BAFF expression alters B cell biology in multiple sclerosis (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Ide Smets, Teresa Prezzemolo, Maya Imbrechts, Klara Mallants, Tania Mitera, Stephanie Humblet-Baron, Bénédicte Dubois, Patrick Matthys, Adrian Liston, An Goris

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    • P0413 - Tumefactive demyelinating lesions under fingolimod. A Tunisian case report (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      ahmed Ghariani, SALMA Sakka, Khadija Senda Moalla, Nouha Farhat, Mariem Damak, Chokri Mhiri

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    • P0414 - Tumefactive demyelination in association with B-cell therapy (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Sarah Gomezelj, Alenka Horvat Ledinek, Uroš Rot, Gregor Brecl Jakob

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    • P0415 - Updated post-approval safety of cladribine tablets in the treatment of multiple sclerosis, with particular reference to respiratory viral infections (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Esther Dodge, Gavin Giovannoni, Joseph Berger, Thomas Leist, Dominic Jack, Andrew Galazka, Axel Nolting, Doris Damian

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    • P0416 - Use of Dimethyl fumarate in real clinical practice and strategy to minimize adverse effects and health resources (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Laura Ramos-Rúa, Ana Rodríguez Regal, Luis Anibarro-García, M. Campo Amigo-Jorrín

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    • P0417 - Utilization, safety, and tolerability of ocrelizumab: year 3 data from the Providence Ocrelizumab Registry (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Kyle Smoot, Tamela Stuchiner, Chiayi Chen, Lois Grote, Stanley Cohan

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    • P0418 - Withdrawal of fingolimod treatment: results from a single-cohort observational study (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Maria Cellerino, Elisabetta Mancuso, Sveva Lenti, nicolò Bruschi, Giacomo Boffa, caterina Lapucci, Luca Roccatagliata, Giovanni Novi, Alice Laroni, Elisabetta Capello, Antonio Uccelli, Matilde Inglese

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    • P0419 -   Racial inequalities in multiple sclerosis research participation: underreporting and underrepresentation (View Presentation)

      Keyword: Epidemiology

      Helen Onuorah, Ashlea Lucas, Odelin Charron, Amanda Montague, Alexis Crispino, Alyssa Aguirre, Verena Kallhoff, Tracee Hall, Ethan Meltzer, Leorah Freeman

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    • P0420 -  Performance on Symbol Digits Modalities Test preceding conversion to Secondary Progressive Multiple Sclerosis (View Presentation)

      Keyword: Prognostic Factors

      Virginija Danylaite Karrenbauer, Lars Forsberg, Jan Hillert

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    • P0421 -  SARS-CoV-2 infection in multiple sclerosis patients: a single center experience in the province of Bergamo, Italy (View Presentation)

      Keyword: Comorbidities

      Marta Radaelli, Valeria Barcella, Marta Conti, Maria Sessa

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    • P0422 - A Case of Multiple Sclerosis in an 18-year-old Female with Juvenile Idiopathic Arthritis on Abatacept (View Presentation)

      Keyword: Comorbidities

      Kelsey Poisson, Katherine Schultz, Tracy Ting, Aram Zabeti

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    • P0423 - A history of migraine headache may not be associated with worse disability or worse neurologic function (View Presentation)

      Keyword: Comorbidities

      Anne Damian, Chen Hu, Kathryn Fitzgerald, Ellen Mowry

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    • P0424 - A Longitudinal Analysis of Functional Outcomes among Young People with MS Using Group-Based Trajectory Modelling (View Presentation)

      Keyword: Epidemiology

      Nikki Ow, Ayse Kuspinar, Nancy Mayo

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    • P0425 - A real-world analysis of ocrelizumab treatment patterns among multiple sclerosis patients in Saskatchewan, Canada (View Presentation)

      Keyword: Epidemiology

      Aman Saini, Ilia Poliakov, Katherine Knox, Chantal Kahovec, Ane Jata, Shirley Macgowan, Michael Levin

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    • P0426 - A systematic assessment of medical diseases and symptoms preceding the first diagnosis of multiple sclerosis (View Presentation)

      Keyword: Epidemiology

      Christiane Gasperi, Alexander Hapfelmeier, Tanja Daltrozzo, Ewan Donnachie, Antonius Schneider, Bernhard Hemmer

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    • P0427 - Absence of latitudinal gradient in oligoclonal bands prevalence in Argentina (View Presentation)

      Keyword: Epidemiology

      Laura Negrotto, Mariano Marrodan, Marcela Fiol, María Gaitán, María Ysrraelit, Carlos Vrech, Agustin Pappolla, Jimena Miguez, Liliana Patrucco, Edgardo Cristiano, Juan Rojas, Adriana Carra, Anibal Chertcoff, Judith Steinberg, alejandra Martinez, Celeste Curbelo, Leila Cohen, Ricardo Alonso, orlando Garcea, Cecilia Pita, Berenice Silva, Geraldine Luetic, Norma Deri, Maria Eugenia Balbuena, Veronica Tkachuk, Edgar Carnero Contentti, Pablo Lopez, Juan Pettinicchi, alejandro Caride, Marcos Burgos, Felisa Leguizamon, Eduardo Knorre, Raúl Piedrabuena, Andres Barboza, Susana Liwacki, Pedro Nofal, Gabriel Volman, Amelia Alves Pinheiro, Javier Hryb, Darío Tavolini, Patricio Blaya, Luciano Recchia, Carolina Mainella, Matías Kohler, Eduardo Kohler, Jorge Blanche, Santiago Tizio, María Saladino, Fernando Caceres, Nora Fernandez Liguori, Luciana Lazaro, Gisela Zanga, Marcela Parada Marcilla, Maria Eugenia Fracaro, Fátima Pagani Cassará, Guido Vazquez, Vladimiro Sinay, Gustavo Sgrilli, Pablo Divi, Miguel Jacobo, Emanuel Silva, Edgardo Reich, Lorena Cabrera, Maria Menichini, Mariano Coppola, Ivan Martos, Juan Viglione, Gustavo Jose, Santiago Bestoso, Ruben Manzi, Diego Giunta, Maria Doldan, Marina Alonso Serena, Jorge Correale

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    • P0428 - Acculturation and lower socioeconomic status are associated with early disability in Hispanic/Latinx with Multiple Sclerosis. (View Presentation)

      Keyword: Epidemiology

      Astrid Diaz, Andrea Martinez, Clara Manrique, Chan Chan, Michael Robers, Silvia Delgado, Ivonne Vicente, Margaret Burnett, Angel Chinea, Jacob McCauley, Lilyana Amezcua

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    • P0429 - Adverse childhood experiences and psychiatric comorbidity in multiple sclerosis and other immune mediated inflammatory disorders (View Presentation)

      Keyword: Comorbidities

      Anthony Wan, Charles Bernstein, Lesley Graff, Scott Patten, Jitender Sareen, John Fisk, James Bolton, Carol Hitchon, James Marriott, Ruth Ann Marrie

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    • P0430 - Anti-TNF induced lupus-like disease and progressive multifocal leukoencephalopathy: a unifying underlying mechanism? (View Presentation)

      Keyword: Comorbidities

      Vassilis Papadopoulos, Clio Mavragani, Theodore Argyrakos, Georgios Velonakis, George Stranjalis, Leonidas Stefanis, Constantinos Kilidireas, Maria Eleftheria Evangelopoulos

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    • P0431 - Assessment of clinical, genetic and immune repertoire data to predict disease activity and progression in RRMS (View Presentation)

      Keyword: Prognostic Factors

      Laura Ferre', Silvia Santoro, Martina Tosi, Elisabetta Mascia, Melissa Sorosina, Ferdinando Clarelli, Lucia Moiola, Vittorio Martinelli, Giancarlo Comi, Massimo Filippi, Federica Esposito

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    • P0432 - Assessment of Depression, Anxiety and Fatigue in relation to diet quality in Multiple Sclerosis (View Presentation)

      Keyword: Epidemiology

      Alice Saul, Bruce Taylor, Wendy Oddy, Steve Simpson-Yap, Ingrid Van Der Mei

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    • P0433 - Association between MS and depression on the risk of macrovascular disease and mortality in England: a population-based matched cohort study (View Presentation)

      Keyword: Comorbidities

      Raffaele Palladino, Ruth Ann Marrie, Azeem Majeed, Jeremy Chataway

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    • P0434 - Associations of depression and anxiety with disease-activity and disability in multiple sclerosis: an analysis of baseline participant characteristics from the CombiRx trial (View Presentation)

      Keyword: Comorbidities

      Yinan Zhang, Christina Glenn, Stacey Cofield, Gary Cutter, Stephen Krieger, Jerry Wolinsky, Fred Lublin

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    • P0435 - Atlas of MS third edition: Methodology for evaluating the validity of country-specific epidemiology data (View Presentation)

      Keyword: Epidemiology

      Lindsay Rechtman, Wendy Kaye, Rachel King, Clare Walton

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    • P0436 - Atlas of MS third edition: Worldwide incidence and clinical features of MS (View Presentation)

      Keyword: Epidemiology

      Lindsay Rechtman, Wendy Kaye, Rachel King, Clare Walton

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    • P0437 - Atlas of MS third edition: Worldwide prevalence of multiple sclerosis (View Presentation)

      Keyword: Epidemiology

      Lindsay Rechtman, Wendy Kaye, Rachel King, Clare Walton

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    • P0439 - Cannabis Use Among People with MS: A 2020 NARCOMS Survey (View Presentation)

      Keyword: Epidemiology

      Amber Salter, Ruth Ann Marie, Gary Cutter, Joshua Steinerman, Karry Smith, Matthew Derosa

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    • P0441 - Cerebrospinal fluid chitinase-3-like protein 1 is associated with disability progression in primary progressive multiple sclerosis (View Presentation)

      Keyword: Prognostic Factors

      Andreja Emersic, Gregor Brecl Jakob, Saša Šega-Jazbec, Alenka Horvat Ledinek, Saša Čučnik, Uroš Rot

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    • P0442 - Cerebrovascular disease and Alzheimer’s disease neuropathology in multiple sclerosis. (View Presentation)

      Keyword: Comorbidities

      Tyler Kaplan, Bichun Ouyang, Dusan Stefoski, Thomas Shoemaker, Michael Ko, Phillip De Jager, Sukriti Nag, David Bennett, Zoe Arvanitakis, Fabian Sierra Morales

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    • P0443 - Characteristics of a population exposed to a disease-modifying drug for multiple sclerosis in the real-world setting (1996-2017) (View Presentation)

      Keyword: Epidemiology

      Huah Shin Ng, Feng Zhu, Elaine Kingwell, Yinshan Zhao, Charity Evans, Larry Svenson, John Fisk, Ruth Ann Marrie, Helen Tremlett

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    • P0444 - Characterization of US-based Hispanic Americans with multiple sclerosis (View Presentation)

      Keyword: Epidemiology

      Lana Zhovtis Ryerson, Tamar Bacon, Wanda Castro-Borrero, James Williams, Kathryn Fitzgerald, Robert T. Naismith, Ellen Mowry, Peter Calabresi, Leigh Charvet, Lauren Krupp

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    • P0445 - Cohort description of Project Y: Searching for the cause of phenotype diversity in MS (View Presentation)

      Keyword: Epidemiology

      Floor Loonstra, Lodewijk De Ruiter, Djoeke Doesburg, Ka Hoo Lam, Zoë Van Lierop, Joep Killestein, Bernard Uitdehaag

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    • P0446 - Comorbid Anxiety, Depression, and Fatigue Symptoms by Disease Modifying Therapy: A National Multiple Sclerosis Cohort (View Presentation)

      Keyword: Comorbidities

      Daniela Pimentel Maldonado, Christopher Hemond, Justin Eusebio, Raffaella Umeton, Idanis Berrios Morales, Ellen Mowry, Carolina Ionete, Kathryn Fitzgerald

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    • P0447 - Comorbidities and  multiple sclerosis in the west of Algeria (View Presentation)

      Keyword: Comorbidities

      zahira Barka Bedrane , Djaoued Bouchenak Khelladi

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    • P0448 - Comorbidities as predictors of all-cause emergency room usage in multiple sclerosis (View Presentation)

      Keyword: Comorbidities

      Elizabeth Gromisch, Aaron Turner, Steven Leipertz, John Beauvais, Jodie Haselkorn

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    • P0449 - Comorbidities at MS diagnosis in Immigrants in Ontario, Canada (View Presentation)

      Keyword: Comorbidities

      Dalia Rotstein, Colleen Maxwell, Karen Tu, Jodi Gatley, Priscila Pequeno, Alexander Kopp, Ruth Ann Marrie

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    • P0450 - Comorbidity patterns in people with multiple sclerosis:  A latent class analysis of the Australian Multiple Sclerosis Longitudinal Study (View Presentation)

      Keyword: Comorbidities

      Lara Marie Lo, Bruce Taylor, Ingrid Van Der Mei

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    • P0451 - Comparing infection-related outcomes in patients with multiple sclerosis and matched controls using administrative claims data (View Presentation)

      Keyword: Comorbidities

      Stephanie Wolfe, Riley Bove, Chris Kozma, Amy Phillips, Danielle Harlow, Carroline Lobo

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    • P0452 - Continued increase of multiple sclerosis and neuromyelitis optica and the north-south gradient in Japan; updates from the 5th nationwide survey (View Presentation)

      Keyword: Epidemiology

      Noriko Isobe, Masaaki Niino, Takuya Matsushita, Yuri Nakamura, Ichiro Nakashima, Mitsuru Watanabe, Yasunari Sakai, Ayako Sakoda, Jin Nakahara, Izumi Kawachi, Hirofumi Ochi, Yuji Nakatsuji, Yusei Miyazaki, Juichi Fujimori, Kenji Kufukihara, Tatsusada Okuno, Shoko Fukumoto, Fumie Hayashi, Kousuke Yonemoto, Ryoji Taira, Yoshikazu Nakamura, Koshi Nakamura, Kiyomi Sakata, Rinako Shimada, Makoto Matsui, Jun-ichi Kira

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    • P0453 - Diagnosis- to-Treatment Interval Has Implication on Quality of Life of patients with Multiple Sclerosis in Montenegro. (View Presentation)

      Keyword: Prognostic Factors

      Jevto Erakovic, Balsa Vujovic, Dragica Milikic, Slavisa Perunicic, Zilha Idrizovic, Milovan Roganovic, Ljiljana Radulovic

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    • P0454 - Diagnosis-to-Treatment Interval Is an Important Factor on the Productivity of  Multiple Sclerosis patients in Montenegro. (View Presentation)

      Keyword: Prognostic Factors

      Jevto Erakovic, Balsa Vujovic, Dragica Milikic, Slavisa Perunicic, Zilha Idrizovic, Milovan Roganovic, Ljiljana Radulovic

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    • P0455 - Disability progression independent of relapse and brain MRI activity and relapse-associated worsening in RRMS  patients  in Poland   (View Presentation)

      Keyword: Prognostic Factors

      Katarzyna Kapica-Topczewska, Independent statistical consultant, Collin, Joanna Tarasiuk, Agata Czarnowska, Monika Chorąży, Anna Mirończuk, Jan Kochanowicz, Alina Kułakowska

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    • P0456 - Epidemiology and MS prevalence in Tehran province, Iran (View Presentation)

      Keyword: Epidemiology

      Sharareh Eskandarieh, Mohamadreza Nasiri, Mohammad Ali Sahraian

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    • P0457 - Evidence of Clostridium perfringens epsilon toxin involvement in neuromyelitis optica (View Presentation)

      Keyword: Epidemiology

      Helen Morcrette, Nicholas Lewis, Michel Popoff, Rosie Everett, Jacqueline Palace, Richard Titball

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    • P0458 - Exploring the polypharmacy phenomenon in newly diagnosed Relapsing Remitting Multiple Sclerosis (View Presentation)

      Keyword: Comorbidities

      Emanuele D'Amico, Aurora Zanghì, Francesco Patti

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    • P0459 - Factors associated with access to disability certificate in patients with MS and NMOSD in Argentina (View Presentation)

      Keyword: Epidemiology

      Berenice Silva, Maria Barbara Eizaguirre, Anibal Chertcoff, JOHANA Bauer, Celeste Curbelo, Veronica Tkachuk, Fátima Pagani Cassará, on behalf RelevarEM study group Relevarem

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    • P0460 - Factors Associated with Treatment Escalation in MS care: Results from an International Conjoint Study (View Presentation)

      Keyword: Prognostic Factors

      Gustavo Saposnik, Xavier Montalban, Óscar Fernández, Ho Jin Kim, Heinz Wiendl, Eva Kubala Havrdová, Mona Foss, Elisabeth Celius, Fernando Caceres, Melinda Magyari, Robert Bermel, Andreia Costa, Maria Terzaghi, Tomas Kalincik, Veronica Popescu, Maria Pia Amato, Jiwon Oh

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    • P0461 - First clinical presentation of multiple sclerosis; Correlation of gender differences, localisation and prognosis (View Presentation)

      Keyword: Prognostic Factors

      Hüsnü Efendi, sena destan Bünül

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    • P0462 - Framingham score, sedentary behaviors, and association with disease activity in Relapsing-Remitting Multiple Sclerosis (View Presentation)

      Keyword: Comorbidities

      Emanuele D'Amico, Aurora Zanghì, Marco Ciaorella, Francesco Patti

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    • P0463 - Healthy-lifestyle-scores associated with lower subsequent fatigue risk in multiple sclerosis using inverse probability treatment weighting (View Presentation)

      Keyword: Epidemiology

      Tracey Weiland, Nupur Nag, Alysha De Livera, George Jelinek, Keryn Taylor, Sandra Neate, William Bevens, Steve Simpson-Yap

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    • P0464 - High prevalence of hypovitaminosis D and its impact on disability in Ecuadorian patients with multiple sclerosis (View Presentation)

      Keyword: Prognostic Factors

      Edgar Patricio Correa-Diaz, MARIA Altamirano-Brito

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    • P0465 - Higher mortality related to disability and social deprivation in a cohort of people with MS in Scotland. (View Presentation)

      Keyword: Epidemiology

      Ewan Deans, Niall Macdougall, Patrick Kearns, Claire Purdie, Claire Millar, Julie Wilkie

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    • P0466 - Hypertension is Undertreated in Patients with Multiple Sclerosis (View Presentation)

      Keyword: Comorbidities

      Sunakshi Bassi, Devon Conway



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    • P0467 - Hypertension, cholesterol levels, and Type II Diabetes are not associated with multiple sclerosis risk: Mendelian randomization analyses (View Presentation)

      Keyword: Epidemiology

      Elina Misicka, Farren Briggs

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    • P0468 - Increasing Frequency of Multiple Sclerosis in Yaroslavl, Russia: A 20 Year Epidemiological Survey (View Presentation)

      Keyword: Epidemiology

      Dmitry Kasatkin, Nikolay Spirin, Igor Stepanov, Vladimir Shadrichev, Natalya Baranova

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    • P0469 - Increasing prevalence of multiple sclerosis in Qatar: 27-year data (View Presentation)

      Keyword: Epidemiology

      Faiza Ibrahim, Beatriz Canibano, Dirk Deleu

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    • P0470 - Initial findings from a dynamic cohort study of patients with multiple sclerosis: A proactive approach for safety and comparative effectiveness (View Presentation)

      Keyword: Epidemiology

      James Plested, Meritxell Sabidó, Michael Batech, Caroline Foch, Emmanuelle Boutmy, Patrice Verpillat

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    • P0471 - Intra-individual variations in multiple sclerosis symptoms are associated with changes in work productivity of people living with multiple sclerosis (View Presentation)

      Keyword: Epidemiology

      Barnabas Bessing, Suzi Claflin, Mohammad Hussain, Jing Chen, C. Leigh Blizzard, Pieter Van Dijk, Andrea Kirk-Brown, Bruce Taylor, Ingrid Van Der Mei

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    • P0472 - Investigating the possible role of dietary supplements intake and risk of primary progressive multiple sclerosis (View Presentation)

      Keyword: Epidemiology

      Nasim Rezaeimanesh, Sharareh Eskandarieh, Abdorreza Naser Moghadasi, Mohammad Ali Sahraian

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    • P0473 - Laboral Status in multiple sclerosis patients whith EDSS 3.5 in Argentina (View Presentation)

      Keyword: Epidemiology

      Amelia Alves Pinheiro, Agustin Secchi, Natalia Valiero, Marcelo Chaves, Maria Abdala

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    • P0474 - MS is associated with higher comorbidity, adverse health behaviors, and healthcare resource usage: population based case-control study in Catalonia. (View Presentation)

      Keyword: Comorbidities

      Simón Cárdenas-Robledo, Susana Otero-Romero, Maria Passarell-Bacardit, Jaume Sastre-Garriga, Xavier Montalban, Mar Tintore

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    • P0475 - Multiple sclerosis (MS) features are related to headache frequency in users of MS Care ConnectTM, a self-efficacy digital application (View Presentation)

      Keyword: Prognostic Factors

      Amy Dix, John Foley, Katherine Geist, Daniel Kantor, Samuel Hunter

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    • P0476 - Multiple sclerosis and acute stroke: are we missing something?  (View Presentation)

      Keyword: Comorbidities

      Miguel Leal Rato, Mónica Santos, Teresa Pinho E Melo, João Ferreira

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    • P0477 - Multiple Sclerosis and Disability Progression in South America, Africa, Asia and the Middle East: A Systematic Review (View Presentation)

      Keyword: Epidemiology

      Mitchell Wallin, Samuele Bonomi, Shan Jin, William Culpepper

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    • P0478 - Multiple sclerosis disability predictors in a Mexican tertiary-care center (View Presentation)

      Keyword: Prognostic Factors

      Ricardo García-Bermúdez, Brenda Bertado-Cortés, Raul Carrera-Pineda

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    • P0479 - Multiple sclerosis predisposes affected individuals for an earlier onset of hypertension. (View Presentation)

      Keyword: Comorbidities

      Farren Briggs, Diane Krill, Eddie Hill, Devon Conway

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    • P0480 - Multiple Sclerosis: Is there a risk of worsening after yellow fever vaccination? (View Presentation)

      Keyword: Epidemiology

      Caroline Papeix, julie Mazoyer, Elisabeth Maillart, Christine Lebrun-Frenay, valerie Pourcher, jean-sebastien Vidal, Catherine Lubetzki

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    • P0481 - Natalizumab discontinuation in a Dutch real-world cohort (View Presentation)

      Keyword: Epidemiology

      Eline Coerver, Mark Wessels, Zoë Van Lierop, Zoé Van Kempen, Joep Killestein, E. Strijbis

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    • P0482 - Objective classification methods result in an increased proportion of secondary progressive multiple sclerosis in five patient registries (View Presentation)

      Keyword: Epidemiology

      Anna Glaser, Lars Forsberg, Ali Manouchehrinia, Ryan Ramanujam, Tim Spelman, Pernilla Klyve, Jiri Drahota, Dana Horakova, Hanna Joensen, Melinda Magyari, David Ellenberger, Alexander Stahmann, Anneke Van Der Walt, Jeff Rodgers, Rod Middleton, Richard Nicholas, Vladimir Bezlyak, Nicholas Adlard, Thomas Hach, Carol Lines, Jan Hillert

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    • P0483 - Prevalence of cancer in multiple sclerosis patients in Argentina: cross sectional study from RelevarEM (View Presentation)

      Keyword: Comorbidities

      Geraldine Luetic, Maria Menichini, Carlos Vrech, Agustin Pappolla, Jimena Miguez, Liliana Patrucco, Jorge Correale, Mariano Marrodan, María Gaitán, Marcela Fiol, Laura Negrotto, María Ysrraelit, Edgardo Cristiano, Adriana Carrá, Anibal Chertcoff, Judith Steinberg, alejandra Martinez, Celeste Curbelo, Leila Cohen, Ricardo Alonso, orlando Garcea, Cecilia Pita, Berenice Silva, Norma Deri, Maria Eugenia Balbuena, Veronica Tkachuk, Edgar Carnero Contentti, Pablo Lopez, Juan Pettinicchi, alejandro Caride, Marcos Burgos, Felisa Leguizamon, Eduardo Knorre, Raúl Piedrabuena, Andres Barboza, Susana Liwacki, Pedro Nofal, Gabriel Volman, Amelia Alves Pinheiro, Javier Hryb, Darío Tavolini, Patricio Blaya, Luciano Recchia, Carolina Mainella, Emanuel Silva, Jorge Blanche, Santiago Tizio, María Saladino, Fernando Caceres, Nora Fernandez Liguori, Luciana Lazaro, Gisela Zanga, Marcela Parada Marcilla, Maria Eugenia Fracaro, Fátima Pagani Cassará, Guido Vazquez, Vladimiro Sinay, Gustavo Sgrilli, Pablo Divi, Miguel Jacobo, Edgardo Reich, Lorena Cabrera, Mariano Coppola, Ivan Martos, Matías Kohler, Eduardo Kohler, Juan Viglione, Gustavo Jose, Santiago Bestoso, Ruben Manzi, Juan Rojas, Marina Alonso Serena, on behalf RelevarEM study group (relevarem)

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    • P0484 - Prevalence of fatigue in multiple sclerosis (View Presentation)

      Keyword: Epidemiology

      Line Broch, Cecilia Simonsen, Heidi Flemmen, Åshild Skardhamar, Elisabeth Celius

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    • P0485 - Prevalence of multiple sclerosis in the OneFlorida Data Trust (View Presentation)

      Keyword: Epidemiology

      Aaron Carlson, Carlos Vervloet Sollero, Quran Wu, Tirisham Gyang, Zhigang Li, Melissa Armstrong

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    • P0486 - Rate of latent infections and vaccination in a cohort of Multiple Sclerosis patients assessed for disease modifying therapies. (View Presentation)

      Keyword: Comorbidities

      Amr Tageldin, Mohammad Mahmud, Sarah Jawad, Leonora Fisniku

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    • P0487 - RDW as a predictor of disability in RRMS (View Presentation)

      Keyword: Prognostic Factors

      Raquel Rocha, Luís Ribeiro, Filipe Correia

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    • P0488 - Relapse recovery in MS: Effect of treatment and contribution to long-term disability (View Presentation)

      Keyword: Prognostic Factors

      Marinos Sotiropoulos, Hrishikesh Lokhande, Brian Healy, Mariann Polgar-Turcsanyi, Bonnie Glanz, Rohit Bakshi, Howard Weiner, Tanuja Chitnis

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    • P0489 - Relationship between comorbidities and health-related quality of life in patients with multiple sclerosis (View Presentation)

      Keyword: Comorbidities

      Mahdi Barzegar, Omid Mirmosayyeb, Mina Rezaei, Alireza Afshari-Safavi, Vahid Shaygannejad

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    • P0490 - Restless leg syndrome in patients with multiple sclerosis (View Presentation)

      Keyword: Comorbidities

      Maroua Bouhlal, naima Chtaou, siham Bouchal, aouatif Elmidaoui, zouhair Souirti, mohammed Belahsen

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    • P0491 - Safety Outcomes after Treatment with Alemtuzumab or Autologous Hematopoietic Stem Cell Transplantation in Multiple Sclerosis Patients (View Presentation)

      Keyword: Epidemiology

      Peter Alping, Joachim Burman, Jan Lycke, Thomas Frisell, Fredrik Piehl

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    • P0492 - Selective serotonin-reuptake inhibitors as potential add-on agents in relapsing-remitting multiple sclerosis patients with suboptimal response (View Presentation)

      Keyword: Comorbidities

      Dmitry Kasatkin, Svetlana Molchanova, Igor Stepanov

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    • P0493 - Severe infections in patients with multiple sclerosis: a nationwide registry study in Argentina (View Presentation)

      Keyword: Epidemiology

      Emanuel Silva, Carlos Vrech, agustín Pappolla, Jimena Miguez, Liliana Patrucco, Jorge Correale, Mariano Marrodan, María Gaitán, Marcela Fiol, laura Negrotto, Celica Ysrraelit, Edgardo Cristiano, Adriana Carrá, Anibal Chertcoff, Judith Steinberg, alejandra Martinez, Celeste Curbelo, Leila Cohen, Ricardo Alonso, orlando Garcea, Cecilia Pita, Berenice Silva, Geraldine Luetic, Norma Deri, Maria Eugenia Balbuena, Veronica Tkachuk, Edgar Carnero Contentti, Pablo Lopez, Juan Pettinicchi, alejandro Caride, Marcos Burgos, Felisa Leguizamon, Eduardo Knorre, Raúl Piedrabuena, Andres Barboza, Susana Liwacki, Pedro Nofal, Gabriel Volman, AMelia Alvez Pinheiro, Javier Hryb, Darío Tavolini, Patricio Blaya, Luciano Recchia, Carolina Mainella, Matías Kohler, Eduardo Kohler, Jorge Blanche, Santiago Tizio, María Saladino, Fernando Caceres, Nora Fernandez Liguori, Luciana Lazaro, Gisela Zanga, Marcela Parada Marcilla, María Fracaro, Fátima Pagani Cassará, Guido Vazquez, Vladimiro Sinay, Gustavo Sgrilli, Pablo Divi, Miguel Jacobo, Edgardo Reich, Lorena Cabrera, Maria Menichini, Mariano Coppola, Ivan Martos, Juan Viglione, Gustavo Jose, Santiago Bestoso, Ruben Manzi, Diego Giunta, Maria Doldan, Marina Alonso Serena, Juan Rojas

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    • P0494 - Socio-demographic and clinical characteristics of patients with multiple sclerosis by race and ethnicity (NARCRMS registry) (View Presentation)

      Keyword: Epidemiology

      Victor Rivera, Pavle Repovic, Ayo Adeyemi, Arman Altincatal, Coraly Perez-Bajandas, Toni Saldana-King, Wanda Castro-Borrero

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    • P0495 - Socioeconomic status and stressful life events risks in development of neuromyelitis Optica spectrum disorder (View Presentation)

      Keyword: Epidemiology

      Sharareh Eskandarieh, Farnaz Rafiee, Abdorreza Naser Moghadasi, Mohammad Ali Sahraian, Amirreza Azimi

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    • P0496 - Telemedicine utilization trends among patients with multiple sclerosis and controls in the United States Veterans Health Administration: 2008-2020 (View Presentation)

      Keyword: Epidemiology

      Hoda Abdel Magid, Shan Jin, William Culpepper, Lorene Nelson, Mitchell Wallin

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    • P0497 - The association between dietary food groups intake and risk of primary progressive multiple sclerosis (View Presentation)

      Keyword: Epidemiology

      Nasim Rezaeimanesh, Sharareh Eskandarieh, Abdorreza Naser Moghadasi, Mohammad Ali Sahraian

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    • P0498 - The effect of national disease modifying therapy subsidy policy on long-term disability outcomes in people with multiple sclerosis (View Presentation)

      Keyword: Epidemiology

      Suzi Claflin, Julie Campbell, Deborah Mason, Tomas Kalincik, Helmut Butzkueven, William Carroll, Andrew Palmer, Steve Simpson-Yap, C. Leigh Blizzard, Ingrid Van Der Mei, Bruce Taylor

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    • P0499 - The epidemiology of optic neuritis in the United Kingdom and implications for consensus diagnostic criteria for multiple sclerosis. (View Presentation)

      Keyword: Epidemiology

      Axel Petzold, Anuradhaa Subramanian, james Galloway, Nicola Adderley, Susan Mollan, Gordon Plant, Krish Nirantharakumar, Alastair Denniston, Tasanee Braithwaite

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    • P0500 - The impact of seasonal fluctuations of vitamin D on long-term disability progression in MS (View Presentation)

      Keyword: Epidemiology

      Kristin Wesnes, Kjell Morten Myhr, Trond Riise, Silje Kvistad, Øivind Torkildsen, Stig Wergeland, Trygve Holmøy, Rune Midgard, Alla Bru, Astrid Edland, Randi Eikeland, Sonia Gosal, Hanne Harbo, Grethe Kleveland, Yvonne Sørenes, Nina Øksendal, Kjetil Bjørnevik

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    • P0501 - The impact of socioeconomic status on the access to disease modifying therapy in people with multiple sclerosis. (View Presentation)

      Keyword: Epidemiology

      Joyutpal Das, Richard Nicholas, Rod Middleton, Jeff Rodgers, David Rog

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    • P0502 - The Natural Course of Multiple Sclerosis Rewritten: A Population Based Study on Disease Demographics and Progression (View Presentation)

      Keyword: Epidemiology

      Cecilia Simonsen, Heidi Flemmen, Line Broch, Cathrine Brunborg, Pål Berg-Hansen, Stine Marit Moen, Elisabeth Celius

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    • P0503 - The Relationship Between Restless Leg Syndrome and Lesion Localization, Effect of Sleep Quality and Fatigue in Multiple Sclerosis Patients (View Presentation)

      Keyword: Comorbidities

      Fatma Akkoyun Arıkan, Gonul Akdag, Alperen Bardakci, Mustafa Cetiner, Sibel Canbaz Kabay

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    • P0504 - The relative contribution of comorbidities on the severity of symptoms in people with Multiple Sclerosis (View Presentation)

      Keyword: Comorbidities

      Lara Marie Lo, Bruce Taylor, Ingrid Van Der Mei

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    • P0505 - Therapeutic sequences of disease-modifying therapies in patients with multiple sclerosis in France over the period 2010-2015 (View Presentation)

      Keyword: Epidemiology

      Soline Leblanc

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    • P0506 - Towards a validated Secondary Progressive Multiple Sclerosis definition: A study from the Italian MS Register (View Presentation)

      Keyword: Epidemiology

      Pietro Iaffaldano, Giuseppe Lucisano, Massimo Filippi, Giancarlo Comi, Marco Onofrj, Francesco Patti, Vincenzo Brescia Morra, Mauro Zaffaroni, Carlo Pozzilli, Eleonora Cocco, Patrizia Sola, Giuseppe Salemi, Matilde Inglese, Roberto Bergamaschi, Simonetta Galgani, Maria Pia Amato, Antonella Conte, Marco Salvetti, Giacomo Lus, Ciro Florio, Rocco Totaro, Marika Vianello, Franco Granella, Elisabetta Ferraro, Umberto Aguglia, Maurizia Gatto, Bianca Orlando, Francesca Sangalli, Giovanna De Luca, Clara Grazia Chisari, Antonio Carotenuto, Damiano Baroncini, Delia Colombo, Mihaela Nica, Damiano Paolicelli, Maria Trojano

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    • P0507 - Treatment of multiple sclerosis during lactation with interferon-beta 1a or glatiramer acetate (View Presentation)

      Keyword: Epidemiology

      Andrea Ciplea, Anna Stahl, Sandra Thiel, Ralf Gold, Kerstin Hellwig

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    • P0508 - Unusual associations of Scleroderma-specific autoantibodies with MS-like disease. Case series and literature review. (View Presentation)

      Keyword: Comorbidities

      Dimitrios Karathanasis, Georgios Velonakis, Constantinos Kilidireas, Clio Mavragani, Maria Eleftheria Evangelopoulos

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    • P0509 - Utility of NEDA-3 status as a predictor of future disease activity (View Presentation)

      Keyword: Prognostic Factors

      Olaf Hoffmann, Hanna Zimmermann, Claudia Chien, Graham Cooper, Joseph Kuchling, Susanna Asseyer, Alexander Brandt, Klemens Ruprecht, Judith Bellmann-Strobl, Friedemann Paul

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    • P0510 - Vascular comorbidity is associated with lower brain volumes in a large multiple sclerosis cohort (View Presentation)

      Keyword: Comorbidities

      Kathryn Fitzgerald, Anne Damian, Devon Conway, Ellen Mowry

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    • P0512 - Vitamin-D-supplement use but not sun exposure associated with higher quality of life in multiple sclerosis (View Presentation)

      Keyword: Epidemiology

      Steve Simpson-Yap, Pia Jelinek, Tracey Weiland, Nupur Nag, Sandra Neate, George Jelinek

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    • P0513 - Work productivity trajectories in Australians living with multiple sclerosis: a group-based modelling approach (View Presentation)

      Keyword: Epidemiology

      Barnabas Bessing, Suzi Claflin, Mohammad Hussain, Jing Chen, C. Leigh Blizzard, Pieter Van Dijk, Andrea Kirk-Brown, Bruce Taylor, Ingrid Van Der Mei

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    • P0514 - Analysis of short chain fatty acids levels in serum and CSF samples of patients with multiple sclerosis and other neurological diseases (View Presentation)

      Keyword: Metabolomics

      Roberto Alvarez-Lafuente, Silvia Pérez-Pérez, María Inmaculada Domínguez-Mozo, María Ángel García-Martínez, Rafael Arroyo

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    • P0515 - Application of Metabolomics to Identify Biofluid Biomarkers for Multiple Sclerosis Diagnosis (View Presentation)

      Keyword: Metabolomics

      Samantha Jack, Robert Powers, Fatema Bhinderwala, Abigail Chase, Heidi Roth

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    • P0516 - BDNF Val66Met polymorphism effect on hippocampal subfields in multiple sclerosis patients (View Presentation)

      Keyword: Genetics and Epigenetics

      Ermelinda De Meo, Elio Prestipino, Emilio Portaccio, Benedetta Nacmias, Silvia Bagnoli, Lorenzo Razzolini, Luisa Pastò, Claudia Niccolai, Bendetta Goretti, Roberto Fratangelo, Laura Tudisco, Angelo Bellinvia, Mattia Fonderico, Antonio Giorgio, Maria Laura Stromillo, Massimo Filippi, Sandro Sorbi, Nicola De Stefano, Maria Pia Amato

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    • P0517 - Circulating miRNA signatures in PPMS (View Presentation)

      Keyword: Genetics and Epigenetics

      María Muñoz San Martín, René Robles Cedeño, Maria Buxó, Luisa María Villar, Jessica Castillo, Bonaventura Casanova-Estruch, Immaculada Gómez, Héctor Perkal, Ester Quintana, Lluís Ramió I Torrentà

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    • P0518 - Clinical and outcome characteristics in familial Multiple Sclerosis (View Presentation)

      Keyword: Genetics and Epigenetics

      SALOUA Mrabet, Emna Derbel, Mohammed Nour, Amina Nasri, Lilia Hmissi, Mouna Bendjebara, Amina Gargouri-Berrechid, Imen Kacem, Riadh Gouider

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    • P0519 - Differential expression of miRNAs in CSF of MS patients depending on their ethnic origin (View Presentation)

      Keyword: Genetics and Epigenetics

      María Muñoz San Martín, René Robles Cedeño, Maria Buxó, Immaculada Gómez, Héctor Perkal, Gary Alvarez Bravo, Ester Quintana, Lluís Ramió I Torrentà

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    • P0520 - Effect of genetic polymorphisms on 25-hydroxyvitamin D levels and supplementation response in patients with relapsing-remitting multiple sclerosis  (View Presentation)

      Keyword: Genetics and Epigenetics

      Saša Gselman, Uroš Potočnik, Mario Gorenjak, Tanja Hojs Fabjan

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    • P0521 - Gene network interpretation of genetic variants and brain tissue expression yields potential drug repositioning strategies for multiple sclerosis (View Presentation)

      Keyword: Genetics and Epigenetics

      Astrid Manuel, yulin Dai, Leorah Freeman, Peilin Jia, Zhongming Zhao

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    • P0522 - Gene-environment interactions in Multiple Sclerosis: a UK Biobank study (View Presentation)

      Keyword: Genetics and Epigenetics

      Benjamin Jacobs, Alastair Noyce, Jonathan Bestwick, Daniel Belete, Gavin Giovannoni, Ruth Dobson

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    • P0523 - Genetic polymorphisms associated with multiple sclerosis and atherosclerosis (View Presentation)

      Keyword: Genetics and Epigenetics

      Tomaž Omerzu, Jožef Magdič, Uroš Potočnik, Mario Gorenjak, Radovan Hojs, Tanja Hojs Fabjan

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    • P0524 - Importance of control group selection for differential miRNA profile studies (View Presentation)

      Keyword: Genetics and Epigenetics

      Ester Quintana, María Muñoz-San Martín, René Robles Cedeño, Olga Belchí, Antonio Villalonga, Ester Muliterno, Imma Gómez, Héctor Perkal, Lluís Ramió I Torrentà

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    • P0525 - Investigating a role of B cells and their depletion in relapsing-remitting Multiple Sclerosis using DNA methylation patterns (View Presentation)

      Keyword: Genetics and Epigenetics

      Ewoud Ewing, Faiez Al Nimer, Lara Kular, Karl Carlström, Pernilla Stridh, Tomas Olsson, Mohsen Khademi, David Gomez-Cabrero, Fredrik Piehl, Maja Jagodic

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    • P0526 - Methylome and transcriptome analysis implicates NBPF locus in PPMS etiopathology (View Presentation)

      Keyword: Genetics and Epigenetics

      Majid Pahlevan Kakhki, Yun Liu, Alexandra Gyllenberg, Tejaswi Venkata Satya Badam, Tojo James, Chiara Starvaggi Cucuzza, Mika Gustafsson, Lars Alfredsson, Jan Hillert, Tomas Olsson, Patrizia Casaccia, Ingrid Kockum, Lara Kular, Maja Jagodic

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    • P0527 - Smoking and multiple sclerosis risk: A Mendelian randomization study (View Presentation)

      Keyword: Genetics and Epigenetics

      Marijne Vandebergh, An Goris



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    • P0528 - T cell composition and polygenic multiple sclerosis risk: a population-based study in children (View Presentation)

      Keyword: Genetics and Epigenetics

      Louk De Mol, Kirsten Looman, Marvin Van Luijn, Philip Jansen, Menno Van Zelm, Joost Smolders, Tonya White, Henriette Moll, Rinze Neuteboom

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    • P0529 - The prevalence of HLA-DRB1*1501 gene polymorphisms in familial cases of multiple sclerosis (View Presentation)

      Keyword: Genetics and Epigenetics

      Yurii Vorokhta, Tetiana Muratova, Svitlana Dribina, Svitlana Oliynik

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    • P0530 - Understanding the metabolic profile of relapses in multiple sclerosis (View Presentation)

      Keyword: Metabolomics

      Tianrong Yeo, Fay Probert, Megan Sealey, Luisa Saldana, Sebastian Hoeckner, Eric Schiffer, Timothy Claridge, David Leppert, Gabriele Deluca, Jacqueline Palace, Jens Kuhle, Daniel Anthony

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    • P0531 - 11C-PIB PET showed a distinct cerebrospinal fluid pattern in patients with progressive multiple sclerosis (View Presentation)

      Keyword: Imaging

      Milena Pitombeira, Fabio Duran, Kenia Campanholo, Aline Souza, Samira Apóstolos-Pereira, Carolina Medeiros Rimkus, Maria Fernanda Mendes, Geraldo Busatto Filho, Dagoberto Callegaro, Carlos Buchpiguel, Daniele De Paula Faria

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    • P0532 - 2D conventional and synthetic brain MRI in the assessment of multiple sclerosis (View Presentation)

      Keyword: Imaging

      Francesc Xavier Aymerich, Cristina Auger, Juli Alonso, Andrea Barros, Margareta Clarke, Juan Mora, Georgina Arrambide, Juan Francisco Corral, Jaume Sastre-Garriga, Alex Rovira

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    • P0533 - A Promising Biomarker Based on T1 Relaxation Time Mapping for Early MS (View Presentation)

      Keyword: Imaging

      Manuela Vaneckova, Jan Krasensky, Tomas Uher, Barbora Srpová, Eva Kubala Havrdová, Michaela Andelova, Karolina Vodehnalova, Dana Horakova, Bénédicte Maréchal, Mario João Fartaria, Veronica Ravano, Gian Franco Piredda, Tobias Kober

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    • P0534 - Advanced magnetic resonance imaging for myelin and axonal density in MS: correlation with clinical disability and serum neurofilament levels (View Presentation)

      Keyword: Imaging

      Reza Rahmanzadeh, Po-Jui Lu, Muhamed Barakovic, Matthias Weigel, Sabine Schaedelin, Thanh D. Nguyen, Simona Schiavi, Alessandro Daducci, Francesco La Rosa, Yi Wang, Meritxell Bach Cuadra, Ernst-Wilhelm Radue, Jens Kuhle, Ludwig Kappos, Cristina Granziera

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    • P0535 - Age-related magnetic susceptibility changes in brain of normal subjects (View Presentation)

      Keyword: Imaging

      Lukas Lambert, Petr Dusek, Adam Pudlac, Manuela Vaneckova, Dana Horakova, Jan Krasensky, Andrea Burgetova

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    • P0536 - An X-Ray Fluorescence Histopathological Correlative Study of a Chronic MS Autopsy (View Presentation)

      Keyword: Imaging

      Christina Vasquez, Yong Guo, Bogdan Popescu, Alicja Kalinowska-Lyszczarz, Oleksandr Gakh, Claudia Lucchinetti

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    • P0537 - Analysis of Vascular abnormalities for lesions in MS using USPIO (View Presentation)

      Keyword: Imaging

      Sagar Buch, Karthikeyan Subramanian, Pavan Jella, Yongsheng Chen, Kamran Shah, Yulin Ge, Evanthia Bernitsas, E. Haacke

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    • P0538 - Applying advanced diffusion MRI in MS: a comparison of 20 diffusion MRI models to identify microstructural features of focal damage (View Presentation)

      Keyword: Imaging

      Muhamed Barakovic, Lester Melie-Garcia, Matthias Weigel, Reza Rahmanzadeh, Jens Kuhle, Ludwig Kappos, Cristina Granziera

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    • P0539 - Artificial double inversion recovery images for cortical lesion visualization in multiple sclerosis (View Presentation)

      Keyword: Imaging

      Piet Bouman, Victor Strijbis, Laura Jonkman, Hanneke Hulst, Jeroen Geurts, Martijn Steenwijk

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    • P0540 - Assessing the relationship between the ratio of T1- T2-weighted images and MRI sequences by using the structural similarity index (View Presentation)

      Keyword: Imaging

      Deborah Pareto, Aran Garcia-Vidal, Juan Francisco Corral, Gemma Piella, Alex Rovira

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    • P0541 - Assessment of automatic decision-support systems for detecting active T2 lesions in multiple sclerosis patients (View Presentation)

      Keyword: Imaging

      Juan Francisco Corral, Juli Alonso, Cristina Auger, Sergi Valverde, Anka Vidal-Jordana, Arnau Oliver, Andrea Barros, Karelys Ng Wong, Mar Tintore, Francesc Xavier Aymerich, Xavier Montalban, Xavier Lladó, Alex Rovira

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    • P0542 - Assessment of central vein sign conspicuity in multicenter 3T FLAIR* imaging (View Presentation)

      Keyword: Imaging

      Melissa Martin, Quy Cao, Brian Renner, Lynn Daboul, Carly O'Donnell, David Moreno-Dominguez, Paulo Rodrigues, John Derbyshire, Christina Azevedo, Amit Bar-Or, Eduardo Caverzasi, Peter Calabresi, Bruce Cree, Leorah Freeman, Roland Henry, Erin Longbrake, Jiwon Oh, Nico Papinutto, Rohini Samudralwar, Matthew Schindler, Elias Sotirchos, Nancy Sicotte, Andrew Solomon, Russell Shinohara, Daniel Reich, Daniel Ontaneda, Pascal Sati

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    • P0543 - Associations between Corpus Callosum Damage, Clinical Disability, and Surface-based Homologous Inter-hemispheric Connectivity in Multiple Sclerosis (View Presentation)

      Keyword: Imaging

      Andrew Russo, Kirsten Stockel, Sean Tobyne, Chanon Ngamsombat, Kristina Brewer, Susie Huang, Eric Klawiter

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    • P0544 - Atrophy of different cortical and subcortical compartments contributes to explain clinical disability in patients with MS: a multicenter study (View Presentation)

      Keyword: Imaging

      Milagros Hidalgo De La Cruz, Maria A. Rocca, Paola Valsasina, Claudio Gobbi, Antonio Gallo, Chiara Zecca, Alvino Bisecco, Massimo Filippi

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    • P0545 - Automatic MS lesions segmentation using LeMan-PV as a clinical decision-support tool: a longitudinal analysis (View Presentation)

      Keyword: Imaging

      Ramona Todea, Germán Barquero, Muhamed Barakovic, Tobias Kober, Mario João Fartaria, Alessandro Cagol, Reza Rahmanzadeh, Riccardo Galbusera, Marios Psychogios, Johanna Lieb, Ludwig Kappos, Jens Kuhle, Meritxell Bach Cuadra, Cristina Granziera

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    • P0546 - Axonal and myelin volume fractions and imaging g-ratio in pediatric MS and MOG-associated disorders. (View Presentation)

      Keyword: Imaging

      Giulia Longoni, Sonya Bells, Robert Brown, Tara Berenbaum, Cynthia De Medeiros, Dumitru Fetco, Sridar Narayanan, Amit Bar-Or, Ruth Ann Marrie, Douglas L Arnold, Brenda Banwell, John Sled, E. Ann Yeh, Donald Mabbott

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    • P0547 - Axonal injury in multiple sclerosis: a multi-compartment diffusion MRI study using high-resolution probabilistic tractography (View Presentation)

      Keyword: Imaging

      Keejin Yoon, Derek Archer, Margareta Clarke, Richard Dortch, Seth Smith, Gary Cutter, Junzhong Xu, Francesca Bagnato

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    • P0548 - Baseline MRI lesions as predictors of clinically definite multiple sclerosis: a post hoc analysis of RENEW and RENEWED (View Presentation)

      Keyword: Imaging

      Steven Galetta, Laura Balcer, Arman Altincatal, Ray Su, Orhan Aktas, Alexander Klistorner, Maria Naylor

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    • P0549 - Baseline neuroaxonal integrity is associated with upper limb function at 96 weeks in secondary progressive multiple sclerosis (View Presentation)

      Keyword: Imaging

      Nevin John, Bhavana Solanky, Floriana De Angelis, Jon Stutters, Ferran Prados, Anisha Doshi, Richard Parker, Christopher Weir, Alberto Calvi, Thomas Williams, Torben Schneider, Domenico Plantone, Anita Monteverdi, David Macmanus, Ian Marshall, Frederik Barkhof, Claudia Wheeler-Kingshott, Jeremy Chataway

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    • P0550 - BOLD signal within and around white matter lesions distinguishes multiple sclerosis and non-specific white matter disease: a 3-dimensional approach (View Presentation)

      Keyword: Imaging

      Dinesh Sivakolundu, Kathryn West, Mark Zuppichini, Andrew Wilson, Tatum Moog, Aiden Blinn, Braeden Newton, Yeqi Wang, Thomas Stanley, Xiaohu Guo, Bart Rypma, Darin Okuda

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    • P0551 - Brain volumes alterations in relapsing-remitting multiple sclerosis patients versus healthy controls in comparison to QyScore® normative database (View Presentation)

      Keyword: Imaging

      Philippe Tran, Enrica Cavedo, Clarisse Longo Dos Santos, Jean-Baptiste Martini, Urielle Thoprakarn

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    • P0552 - BrainGraph A Novel Visualization of MRI Data as a 3D Graph to Reveal Temporal Features of Disease Progression In Patients with Multiple Sclerosis (View Presentation)

      Keyword: Imaging

      David Hughes, Weidong Yang, Kelly Leyden, Michael Iv, Anisha Keshavan

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    • P0553 - Bundle-specific microstructural alterations in normal appearing white matter of cognitively preserved MS patients using advanced diffusion MRI (View Presentation)

      Keyword: Imaging

      Jan Bitterli, Felix Morency, Laura Gaetano, Amanda Pfister, Anna Altermatt, Priska Zuber, Charidimos Tsagkas, Athina Papadopoulou, Jens Wuerfel, Till Sprenger, Ludwig Kappos, Maxime Descoteaux, Stefano Magon

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    • P0554 - Cervical disc disease is not associated with demyelanting lesions in multiple sclerosis (View Presentation)

      Keyword: Imaging

      marwan Alkrenawi, Shmuel Appel, Michael Osherov, Azaria Simonovich, Jonathan Droujin, Ron Milo

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    • P0555 - Characterization of MRI Activity Following Treatment with Ocrelizumab for Multiple Sclerosis (View Presentation)

      Keyword: Imaging

      Shamik Bhattacharyya, Ahya Ali, Rohit Bakshi

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    • P0556 - Characterization of multiple sclerosis lesions with distinct clinical correlates through diffusion MRI properties (View Presentation)

      Keyword: Imaging

      Eloy Martinez-Heras, Eli Solana, Ferran Prados, Magi Andorra, Aleix Solanes, Elisabet Lopez-Soley, Carmen Montejo, Irene Pulido-Valdeolivas, Salut Alba-Arbalat, Nuria Sola-Valls, Maria Sepulveda, Yolanda Blanco, Albert Saiz, Joaquim Radua, Sara Llufriu

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    • P0557 - Characterizing 1-year development of cervical cord atrophy across different MS phenotypes: a voxel-wise, multicenter analysis (View Presentation)

      Keyword: Imaging

      Paola Valsasina, Maria A. Rocca, Claudio Gobbi, Chiara Zecca, Alex Rovira, Jaume Sastre-Garriga, Hugh Kirney, Olga Ciccarelli, Lucy Matthews, Jacqueline Palace, Antonio Gallo, Alvino Bisecco, Achim Gass, Philipp Eisele, Massimo Filippi

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    • P0558 - Clinical predictors of brain MRI gadolinium enhancing lesions in Multiple Sclerosis patients (View Presentation)

      Keyword: Imaging

      Filipa Serrazina, Manuel Salavisa, Ana Sofia Correia

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    • P0559 - Cluster Analysis discriminates Multiple Sclerosis Patients based on Lesion Size and Myelin Content (View Presentation)

      Keyword: Imaging

      Ulrike W Kaunzner, Sandra Hurtado Rua, Sneha Pandya, Amy Kuceyeski, Ceren Tozlu, Elizabeth Sweeney, Nancy Nealon, Jai Perumal, Tim Vartanian, Thanh D. Nguyen, Susan Gauthier

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    • P0560 - Comparative Myelin Water Imaging in Relapsing Remitting and Secondary Progressive Multiple Sclerosis (View Presentation)

      Keyword: Imaging

      Caroline Koehler, Paul Kuntke, Hannes Wahl, Stefanie Fischer, Tjalf Ziemssen, Jennifer Linn, Hagen H. Kitzler

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    • P0561 - Comparison of different global network measures and tissue microstructural features to capture the ongoing brain damage in multiple sclerosis (View Presentation)

      Keyword: Imaging

      Sara Bosticardo, Simona Schiavi, Muhamed Barakovic, Matthias Weigel, Ludwig Kappos, Cristina Granziera, Alessandro Daducci

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    • P0562 - Cortical lesions are not associated with leptomeningeal enhancement in a cohort of adults with MS. (View Presentation)

      Keyword: Imaging

      Mark Morrison, Erin Beck, Pascal Sati, Hadar Kolb, Daniel Reich

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    • P0563 - Could light scattering measured with frequency domain near-infrared spectroscopy provide new information on cerebral edema in MS? (View Presentation)

      Keyword: Imaging

      Ayden Hansen, Damilola Adingupu, Taelor Evans, Qandeel Shafqat, Scott Jarvis, Lenora Brown, Luanne Metz, Jeff Dunn

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    • P0564 - Depth-dependent cortical distributions of quantitative 7 T MRI parameters are associated with disability in MS (View Presentation)

      Keyword: Imaging

      Alfonso Lema Dopico, Seongjin Choi, Daniel Harrison

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    • P0565 - Different Temporal Evolution of Diffusely Abnormal White Matter Volumes in Relapsing Remitting and Secondary Progressive MS (View Presentation)

      Keyword: Imaging

      Mahsa Dadar, Sawsan Mahmoud, Maryna Zhernovaia, Sridar Narayanan, Louis Collins, Douglas L Arnold, Josefina Maranzano

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    • P0566 - Diffusion tensor imaging of the nucleus basalis of Meynert reveals associations with cognitive state in patients with multiple sclerosis (View Presentation)

      Keyword: Imaging

      Franziska Hildesheim, Ralph Benedict, Robert Zivadinov, Michael Dwyer, Tom Fuchs, Dejan Jakimovski, Bianca Weinstock-Guttman, Niels Bergsland

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    • P0567 - Diffusion-based Structural connectivity abnormalities in MS phenotypes. (View Presentation)

      Keyword: Imaging

      Eli Solana, Eloy Martinez-Heras, Elisabet Lopez-Soley, Albert Saiz, Elena Martinez-Lapiscina, Pablo Villoslada, Dewen Meng, Rob Dineen, Maria A. Rocca, Massimo Filippi, Olga Ciccarelli, Sara Collorone, Ahmed Toosy, Ferran Prados, Sergiu Groppa, Vinzenz Fleischer, Alex Rovira, Deborah Pareto, Jaume Sastre-Garriga, Sara Llufriu

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    • P0568 - Disappearance of spinal cord lesions in multiple sclerosis. A longitudinal study of 8 patients. (View Presentation)

      Keyword: Imaging

      Valeriya Tsydenzhapova, Clarisse Dalliere, Xavier Ayrignac, Pierre Labauge

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    • P0569 - Distribution profile of T1 relaxation time in white matter lesions on 7-Tesla MRI in multiple sclerosis reflects disease severity and phenotype (View Presentation)

      Keyword: Imaging

      Seongjin Choi, Ryan Mizell, Margaret Spini, Jun Hua, Daniel Harrison

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    • P0570 - Dynamic functional connectivity as a neural correlate of fatigue in multiple sclerosis (View Presentation)

      Keyword: Imaging

      Floris Tijhuis, Tommy Broeders, Fernando Santos, Joep Killestein, Cyra Leurs, Quinten Van Geest, Jeroen Geurts, Linda Douw, Hanneke Hulst

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    • P0571 - Evaluating agreement between Mean Upper Cervical Cord Area measurements from 3D-FLAIR and 3D-T1 brain images (View Presentation)

      Keyword: Imaging

      Gianfranco Costantini, Ferran Prados, Chiara Bosa, Maria Barbara Pasanisi, Valentina Schillaci, Anastasia Alteno, Maria Ferraris, Umberto Gava, Adriano Chiò, Marco Vercellino, Paola Cavalla

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    • P0572 - Evaluation of cerebellar function scores in relation to cerebellar axonal loss in multiple sclerosis. (View Presentation)

      Keyword: Imaging

      Frederique Boonstra, Sanuji Gajamange, Gustavo Noffs, Thushara Perera, Myrte Strik, Adam Vogel, Helmut Butzkueven, Andrew Evans, Anneke Van Der Walt, Scott Kolbe

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  • PO03 - On-Demand ePosters P0573-P0858

    • Type: Poster
    • Presentations: 281
    Presented on: 9/11/2020, 08:00
    View Posters

    • P0573 - Evolution of Diffusely Abnormal White Matter and its relationship to Progression in Primary Progressive MS (View Presentation)

      Keyword: Imaging

      Mahsa Dadar, Sawsan Mahmoud, Maryna Zhernovaia, Sridar Narayanan, Louis Collins, Douglas L Arnold, Josefina Maranzano

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    • P0574 - Expansion of chronic lesions associated with disease progression in RRMS patients. (View Presentation)

      Keyword: Imaging

      Alexander Klistorner, Michael Barnett, Md, Con Yiannikas, Joshua Barton, Stuart Graham, Samuel Klistorner

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    • P0575 - Exploring demyelination and brain atrophy in multiple sclerosis using quantitative magnetic resonance imaging (View Presentation)

      Keyword: Imaging

      Lenka Novakova, Markus Axelsson, Clas Malmeström, Jan Lycke

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    • P0576 - Exploring the Corticospinal Tract in Progressive Multiple Sclerosis: A Transcranial Magnetic Stimulation and Magnetic Resonance Imaging Study (View Presentation)

      Keyword: Imaging

      Paul Kauv, Moussa Antoine Chalah, Alain Créange, Jean-Pascal Lefaucheur, Jérôme Hodel, Samar S. Ayache

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    • P0577 - Feasibility of thalamic atrophy measurement in clinical routine using artificial intelligence: Results from multi-center study in RRMS patients (View Presentation)

      Keyword: Imaging

      Robert Zivadinov, Niels Bergsland, Meredith Millman, Dejan Jakimovski, Deepa Ramasamy, Bianca Weinstock-Guttman, Myassar Zarif, Mitch Freedman, Samuel Hunter, Stanley Cohan, Keith Edwards, Brian Steingo, Rana Zabad, Matthew Baker, Marin Belkin, Pavle Repovic, Amir Mazhari, Abigail Chase, Jason Silversteen, Derek Smith, Donald Negroski, Marc Feinberg, Stephen Newman, Gabriel Pardo, Jon Riolo, Diego Silva, Michael Dwyer

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    • P0578 - Five years functional connectivity reorganization without clinical or cognitive decline in MS (View Presentation)

      Keyword: Imaging

      Einar Høgestøl, Samuele Ghezzo, Gro Nygaard, Thomas Espeseth, Piotr Sowa, Mona Beyer, Hanne Harbo, Lars Westlye, Hanneke Hulst

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    • P0579 - FLAIR-only joint volumetric analysis of brain lesions and atrophy in clinically isolated syndrome (CIS) suggestive of MS (View Presentation)

      Keyword: Imaging

      Olivia Goodkin, Ferran Prados, Sjoerd Vos, Hugh Pemberton, Sara Collorone, Marloes Hagens, M. Jorge Cardoso, Tarek Yousry, John Thornton, Carole Sudre, Frederik Barkhof

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    • P0580 - Focal inflammatory activity and lesion repair are associated with brain atrophy rates in MS patients (View Presentation)

      Keyword: Imaging

      Alessandro Cagol, Muhamed Barakovic, Pascal Benkert, Ramona-Alexandra Todea, Reza Rahmanzadeh, Riccardo Galbusera, Sabine Schaedelin, Po-Jui Lu, Matthias Weigel, Ernst-Wilhelm Radue, Özgür Yaldizli, Johannes Lorscheider, Tim Sinnecker, Mario João Fartaria, Stefanie Müller, Lutz Achtnichts, Jochen Vehoff, Giulio Disanto, Oliver Findling, Andrew Chan, Anke Salmen, Caroline Pot, Patrice Lalive, Chiara Zecca, Tobias Derfuss, Johanna Lieb, Luca Remonda, Franca Wagner, Maria Vargas, Philippe Maeder, Emanuele Pravata, Johannes Weber, Claudio Gobbi, David Leppert, Vincenzo Silani, Jens Wuerfel, Ludwig Kappos, Jens Kuhle, Cristina Granziera

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    • P0581 - Gradient echo magnetic resonance imaging to detect central vein sign in patients with Multiple Sclerosis (View Presentation)

      Keyword: Imaging

      Victoria Levasseur, Biao Xiang, Amber Salter, Samantha Lancia, Dmitriy Yablonskiy, Anne Cross

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    • P0582 - High resolution functional mapping of upper and lower limb sensorimotor function in minimally disabled people with multiple sclerosis using 7T MRI (View Presentation)

      Keyword: Imaging

      Myrte Strik, Camille Shanahan, Anneke Van Der Walt, Frederique Boonstra, Rebecca Glarin, Mary Galea, Trevor Kilpatrick, Jeroen Geurts, Menno Schoonheim, Scott Kolbe

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    • P0583 - High throughput lesion evaluation and quality control for incorporating quantitative imaging metrics into clinical practice (View Presentation)

      Keyword: Imaging

      Anisha Keshavan, Kelly Leyden, Michael Iv, Barbara Dappert, Michael Becich, Michael Towbin, David Hughes, Annalise Miner, Revere Kinkel, Jennifer Graves

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    • P0584 - Histological analysis of slowly expanding lesions in multiple sclerosis: case report (View Presentation)

      Keyword: Imaging

      Yufan Zheng, Bruce Trapp, Daniel Ontaneda, Kunio Nakamura

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    • P0585 - Hurst exponent as an imaging biomarker of impairment in multiple sclerosis (View Presentation)

      Keyword: Imaging

      Ceren Tozlu, Keith Jamison, Amanda Simon, Elvisha Dhamala, Susan Gauthier, Amy Kuceyeski

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    • P0586 - Impact of Cladribine Tablets on Brain Volume Protection in Highly Active MS (View Presentation)

      Keyword: Imaging

      Alaleh Raji, Gerhard Winkler

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    • P0587 - Impact of siponimod on myelination as assessed by MTR across SPMS subgroups: Post-hoc analysis from the EXPAND MRI substudy (View Presentation)

      Keyword: Imaging

      Douglas L. Arnold, Amit Bar-Or, Bruce A.C. Cree, Gavin Giovannoni, Ralf Gold, Patrick Vermersch, Daniela Piani-Meier, Thomas Hach, Sophie Arnould, Goeril Karlsson, Ludwig Kappos, Robert Fox

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    • P0588 - Implementation strategy of an international standardized MRI protocol for the diagnosis and follow-up of MS patients (View Presentation)

      Keyword: Imaging

      Anthony Traboulsee, Jiwon Oh, Scott Newsome, Frederik Barkhof, Daniel Reich, June Halper, Lori Saslow, David Li, the Cmsc Mri Guidelines Working Group

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    • P0589 - Implications of registration of white matter structures for MS connectome analysis (View Presentation)

      Keyword: Imaging

      Justin Garber, Michael Barnett, Fernando Calamante, Chenyu Wang

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    • P0590 - Improved detection of clinically relevant MRI findings in Multiple Sclerosis radiology reports using FDA-approved quantitative software (View Presentation)

      Keyword: Imaging

      Kelly Leyden, Anisha Keshavan, Michael Iv

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    • P0591 - In vivo cortical lesions detection as an early hallmark of multiple sclerosis. (View Presentation)

      Keyword: Imaging

      Pierre Durozard, Adil Maarouf, Audrey Rico, Clémence Boutière, Sarah Demortière, Sylviane Confort-Gouny, Jan-Patrick Stellmann, Wafaa Zaaraoui, Maxime Guye, Jean Philippe Ranjeva, Bertrand Audoin, Jean Pelletier

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    • P0592 - In-clinic performance of MSPie, an image analysis prototype for automated MRI quantitative point-of-care metrics in MS (View Presentation)

      Keyword: Imaging

      Beatrix Bevernage, Hagen H. Kitzler, Stephen Jones, Maria Blefari, Ricardo Corredor-Jerez, Till Huelnhagen, Shirley Liao, Mario João Fartaria, Adrian Tsang, Rodrigo Perea, Paul Kuntke, Sara Makaretz, James R. Williams, Richard Rudick, Tobias Kober, Elizabeth Fisher

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    • P0593 - Increased perfusion and microstructural damage precede demyelination in newly forming MS lesions (View Presentation)

      Keyword: Imaging

      Emanuele Morena, Vito Ricigliano, Annalisa Colombi, Arya Yazdan Panah, Maryem Hamzaoui, Benedetta Bodini, Matteo Tonietto, Bruno Stankoff

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    • P0594 - Interpreting brain parenchymal fraction by comparison to healthy volunteers: Initial results from the MS PATHS normative sub-study (View Presentation)

      Keyword: Imaging

      Beatrix Bevernage, Stephen Jones, Adrian Tsang, Rodrigo Perea, Shirley Liao, Yu-Chen Su, Tammie Benzinger, Maria Blefari, Ricardo Corredor-Jerez, Mario João Fartaria, Till Huelnhagen, Hagen H. Kitzler, Tobias Kober, Sara Makaretz, Alex Rovira, Madalina Tivarus, James R. Williams, Richard Rudick, Elizabeth Fisher

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    • P0595 - Investigating the relation between global structural network measures and serum neurofilament light in multiple sclerosis (View Presentation)

      Keyword: Imaging

      Sara Bosticardo, Simona Schiavi, Muhamed Barakovic, Matthias Weigel, Ernst-Wilhelm Radue, Ludwig Kappos, Jens Kuhle, Alessandro Daducci, Cristina Granziera

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    • P0596 - Investigation of lesion volume dynamics in MS patients as detected by Voxel-Guided Morphometry – A multi center study (View Presentation)

      Keyword: Imaging

      Matthias Kraemer, Andreas Dabringhaus, Johannes Gregori, Stefan Hoffmann, Ulf Schulze-Topphoff, Benedict Rauser, Benjamin Ettle, Achim Gass

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    • P0597 - Lesional myelin repair, as measured with positron emission tomography, effectively protects the integrity of surrounding tissues (View Presentation)

      Keyword: Imaging

      Vito Ricigliano, Matteo Tonietto, Emilie Poirion, Bruno Stankoff, Benedetta Bodini

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    • P0598 - LesionQuant for assessment of MRI in multiple sclerosis- a promising supplement to the visual scan inspection  (View Presentation)

      Keyword: Imaging

      Synne Brune, Einar Høgestøl, Vanja Cengija, Pål Berg-Hansen, Piotr Sowa, Gro Nygård, Hanne Harbo, Mona Beyer

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    • P0599 - Linking microstructural integrity and motor cortex excitability in multiple sclerosis (View Presentation)

      Keyword: Imaging

      Angela Radetz, Kalina Mladenova, Dumitru Ciolac, Gabriel Gonzalez-Escamilla, Vinzenz Fleischer, Julia Krämer, Jacqueline Trotter, Sven Meuth, Muthuraman Muthuraman, Sergiu Groppa

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    • P0600 - Longitudinal evolution of cortical lesions in an Italian cohort of multiple sclerosis patients (View Presentation)

      Keyword: Imaging

      Erica Curti, Stefania Graziuso, Veronica Bazzurri, Alessia Fiore, Chiara Ganazzoli, Giorgia Ogliari, Elena Tsantes, Franco Granella

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    • P0601 - Longitudinal functional modularisation and causality dynamics during de- and remyelination (View Presentation)

      Keyword: Imaging

      Muthuraman Muthuraman, Manuela Cerina, Gabriel Gonzalez-Escamilla, Vinzenz Fleischer, Marco Gallus, Andre Dik, Lydia Wachsmuth, Peter Hundehege, Patrick Schiffler, Jan-Gerd Tenberge, Venu Narayanan, Julia Krämer, Thomas Budde, Cornelius Faber, Sven Meuth, Sergiu Groppa

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    • P0602 - Long-lasting effects of optic neuritis on anatomical and functional visual network patterns (View Presentation)

      Keyword: Imaging

      Yael Backner, Sol Zamir, Panayiota Petrou, Friedemann Paul, Dimitrios Karussis, Netta Levin

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    • P0603 - MAGNON – Implementation and Contribution of Lublin Criteria and quantitative MRI-Analysis for daily clinical routine of MS Patients (View Presentation)

      Keyword: Imaging

      Olaf Hoffmann, Katrin Schuh, Veronika Winkelmann

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    • P0604 - Mild Gray Matter Atrophy in Patients with Longstanding Multiple Sclerosis and Favorable Clinical Course  (View Presentation)

      Keyword: Imaging

      Rosa Cortese, Marco Battaglini, Francesca Parodi, Maria Laura Stromillo, Emilio Portaccio, Lorenzo Razzolini, Antonio Giorgio, Maria Pia Sormani, Maria Pia Amato, Nicola De Stefano

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    • P0605 - More dynamic functional network switching in cognitively declining multiple sclerosis patients (View Presentation)

      Keyword: Imaging

      Tommy Broeders, Linda Douw, Anand Eijlers, Iris Dekker, Bernard Uitdehaag, Frederik Barkhof, Hanneke Hulst, Christiaan Vinkers, Jeroen Geurts, Menno Schoonheim

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    • P0606 - MRI changes over the disease course in a large multiple sclerosis clinical cohort (View Presentation)

      Keyword: Imaging

      Gabrielle Macaron, Kunio Nakamura, Ryan Honomischl, Nicolas Thompson, Scott Husak, Stephen Jones, Robert Bermel, Kedar Mahajan, Jeffrey Cohen, Daniel Ontaneda

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    • P0607 - MRI Characterization of Damage in and Around Lesions in Pediatric MS and MOG-Associated Disorders (View Presentation)

      Keyword: Imaging

      Robert Brown, Sonya Bells, Tara Berenbaum, Cynthia De Medeiros, Dumitru Fetco, Sridar Narayanan, Amit Bar-Or, Ruth Ann Marrie, Douglas L Arnold, Brenda Banwell, John Sled, Donald Mabbott, E. Ann Yeh, Giulia Longoni

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    • P0608 - MRI-based clustering of MS patients in the perspective of personalized medicine (View Presentation)

      Keyword: Imaging

      Raffaello Bonacchi, Maria A. Rocca, Alessandro Meani, Elisabetta Pagani, Massimo Filippi

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    • P0609 - Multimodal MRI of the Brain to Improve Prediction of Disease Progression in Multiple Sclerosis (View Presentation)

      Keyword: Imaging

      Birgit Helmlinger, Daniela Pinter, Stefan Ropele, Lukas Pirpamer, Michael Khalil, Christian Enzinger

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    • P0610 - Multiparametric MRI investigation of enlarging and shrinking MS lesions (View Presentation)

      Keyword: Imaging

      Philipp Eisele, Matthias Kraemer, Andreas Dabringhaus, Anne Ebert, Luc Bracoud, Michael Platten, Imke Metz, Lucas Schirmer, Achim Gass

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    • P0611 - Neurite density explains cortical T1-/T2-weighted ratio in multiple sclerosis (View Presentation)

      Keyword: Imaging

      Paolo Preziosa, Piet Bouman, Svenja Kiljan, Martijn Steenwijk, Petra Pouwels, Maria A. Rocca, Massimo Filippi, Jeroen Geurts, Laura Jonkman

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    • P0612 - New cortical lesions are rare in an MS cohort with stable white matter lesions: a 7T multicontrast longitudinal study (View Presentation)

      Keyword: Imaging

      Erin Beck, Josefina Maranzano, Pascal Sati, Stefano Filippini, Mark Morrison, Nicholas Luciano, Daniel Suto, Irene Cortese, Sridar Narayanan, Daniel Reich

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    • P0613 - Ocrelizumab Reduces Regional Brain Atrophy in Relapsing Multiple Sclerosis as Assessed by Longitudinal Deformation-based Morphometry (View Presentation)

      Keyword: Imaging

      Zhuang Song, AnithaPriya Krishnan, Laura Gaetano, David Clayton, Alex De Crespigny, Thomas Bengtsson, Richard Carano

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    • P0614 - Perilesional neurodegenerative injury in MS: relations with focal lesions and disability (View Presentation)

      Keyword: Imaging

      Margareta Clarke, Dhairya Lakhani, Sijin Wen, Si Gao, Seth Smith, Richard Dortch, Junzhong Xu, Francesca Bagnato

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    • P0615 - Physical disability is related to resting-state network atrophy and altered MEG-based functional network topology in multiple sclerosis. (View Presentation)

      Keyword: Imaging

      Lodewijk De Ruiter, Shanna Kulik, I. Nauta, Jeroen Geurts, Cornelis Stam, Arjan Hillebrand, Bernard Uitdehaag, E. Strijbis, Menno Schoonheim

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    • P0616 - PiB-PET and MRI myelin water fraction provide complementary information about myelin (View Presentation)

      Keyword: Imaging

      Irene Vavasour, Nasim Vafai, Philippe Beauchemain, Alexandru Badalan, Chironjeev Kanjilal, Anthony Traboulsee, Elham Shahinfard, Vesna Sossi, Shannon Kolind, Robert Carruthers

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    • P0617 - Predicting Disease Progression in Multiple Sclerosis from Clinical Routine T2-FLAIR MRI (View Presentation)

      Keyword: Imaging

      Tom Fuchs, Michael Dwyer, Dejan Jakimovski, Niels Bergsland, Deepa Ramasamy, Bianca Weinstock-Guttman, Ralph Benedict, Robert Zivadinov

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    • P0618 - Prednisolone treatment during the first episode in multiple sclerosis is associated with cortical thinning in the right medial orbitofrontal cortex. (View Presentation)

      Keyword: Imaging

      Marlene Tahedl

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    • P0619 - Prefrontal Metabolism Explains Processing Speed Ability in Multiple Sclerosis: A Calibrated fMRI study (View Presentation)

      Keyword: Imaging

      Mark Zuppichini, Dinesh Sivakolundu, Kathryn West, Darin Okuda, Bart Rypma

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    • P0620 - QSM detects greater rate of reduction in lesion magnetic susceptibility in patients treated with Dimethyl Fumarate over Glatiramer Acetate treatment (View Presentation)

      Keyword: Imaging

      Nicole Zinger, Thanh D. Nguyen, Elizabeth Sweeney, Joseph Comunale, Weiyuan Huang, Xianfu Luo, Lily Zexter, Melanie Marcille, Ulrike W Kaunzner, Nancy Nealon, Jai Perumal, Tim Vartanian, Yi Wang, David Pitt, Susan Gauthier

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    • P0621 - q-Space Myelin Map imaging for longitudinal analysis of remyelination in multiple sclerosis patients treated with dimethyl fumarate (View Presentation)

      Keyword: Imaging

      Kenji Kufukihara, Satoshi Kitagawa, Yayoi Sato, Mariko Tanikawa, Junichi Hata, Shigeaki Suzuki, Masaya Nakamura, Hideyuki Okano

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    • P0622 - Quanitifying the T1 hypointensity of MS lesions (View Presentation)

      Keyword: Imaging

      Justin Garber, Michael Barnett, Md

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    • P0623 - Quantifying Cervical and Thoracic Cord Atrophy in Multiple Sclerosis  (View Presentation)

      Keyword: Imaging

      Yair Mina, Shila Azodi, Tsemacha Dubuche, Frances Andrada, Ikesinachi Osuorah, Joan Ohayon, Irene Cortese, Tianxia Wu, Kory Johnson, Daniel Reich, Govind Nair, Steven Jacobson

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    • P0624 - Quantitative multiparametric 3T-MRI of postmortem multiple sclerosis whole brains (View Presentation)

      Keyword: Imaging

      Riccardo Galbusera, Muhamed Barakovic, Matthias Weigel, Po-Jui Lu, Peter Dechent, Erik Bahn, Franziska Van Der Meer, Ludwig Kappos, Wolfgang Brück, Christine Stadelmann, Cristina Granziera

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    • P0625 - Quantitative Susceptibility Mapping in the cortical ribbon of MS patients and its dependence on cortical thinning. (View Presentation)

      Keyword: Imaging

      Marco Castellaro, Agnese Tamanti, Roberta Magliozzi, Alessandro Palombit, Francesco Crescenzo, Stefania Montemezzi, Francesca Pizzini, Alessandra Bertoldo, Massimiliano Calabrese

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    • P0626 - Quantitative Susceptibility Mapping at 7 Tesla detects ongoing active lesions in relapse-free RRMS patients (View Presentation)

      Keyword: Imaging

      NURUL HAFIZAH Mohd Shukur, Myrte Strik, Negin Yaghmaie, Anneke Van Der Walt, Trevor Kilpatrick, Warda Syeda, Leigh Johnston, Jon Cleary, Meng Law, Elaine Lui, Frederique Boonstra, Scott Kolbe

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    • P0627 - Quantitative T1 changes relate to infratentorial pathology in early multiple sclerosis. (View Presentation)

      Keyword: Imaging

      Michaela Andelova, Gian Franco Piredda, Karolina Vodehnalova, Jan Krasensky, Tereza Hrnciarova, Barbora Srpová, Tomas Uher, Ingrid Menkyova, Dominika Stastna, Dana Horakova, Veronica Ravano, Bénédicte Maréchal, Mario João Fartaria, Tom Hilbert, Tobias Kober, Manuela Vaneckova

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    • P0628 - Quantitative T1 deviations in brain lesions and NAWM improve the clinico-radiological correlation in early MS (View Presentation)

      Keyword: Imaging

      Gian Franco Piredda, Tom Hilbert, Manuela Vaneckova, Jan Krasensky, Tomas Uher, Barbora Srpová, Eva Havrdova, Michaela Andelova, Karolina Vodehnalova, Dana Horakova, Veronica Ravano, Mario João Fartaria, Bénédicte Maréchal, Jean-Philippe Thiran, Tobias Kober

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    • P0629 - QUANTUM – Quantitative and standardized imaging in daily clinical routine of multiple sclerosis patients (View Presentation)

      Keyword: Imaging

      Katrin Schuh, Lothar Spies, Roland Opfer, Manda Jankovic, Birte Elias-Hamp, Marek Jauss

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    • P0630 - Racial/ethnic disparities in volumetric MRI correlates of clinical disability between Hispanic/Latino and Caucasian multiple sclerosis patients (View Presentation)

      Keyword: Imaging

      Carlos A. Pérez, Alireza Salehbeiki, Jerry Wolinsky, John A. Lincoln

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    • P0631 - Recommendations for the coordination of Neurology and Neuroradiology departments in the management of patients with multiple sclerosis (View Presentation)

      Keyword: Imaging

      Sara Llufriu, Eduardo Agüera, Francisco Bravo, Lucienne Costa-Frossard, Victoria Galán, Laura Koren, Andrés Labiano, Lamberto Landete, Adelaida León, Daniel Lourido, Patricia Martín, José Meca-Lallana, María Dolores Monedero, Ester Moral, Luis Requeni, Irat Zubizarreta, Àlex Rovira

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    • P0632 - Reduced brain integrity slows down and increases low alpha power in multiple sclerosis (View Presentation)

      Keyword: Imaging

      Jeroen Van Schependom, Diego Vidaurre, Lars Costers, Martin Sjogard, Diana Sima, Dirk Smeets, Marie D'Hooghe, Miguel D'Haeseleer, Gustavo Deco, Vincent Wens, Xavier De Tiège, Serge Goldman, Mark Woolrich, Guy Nagels

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    • P0634 - Relationship Between Cognitive Functioning and 7T Thalamic Imaging Metrics in Fingolimod-Treated MS Patients and Healthy Controls (View Presentation)

      Keyword: Imaging

      Devon Conway, Sarah Planchon, Se Hong Oh, Kunio Nakamura, Nicolas Thompson, Ken Sakaie, Daniel Ontaneda

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    • P0635 - Relationship between mood disturbance and cerebellar volume and structural connectivity in multiple sclerosis  (View Presentation)

      Keyword: Imaging

      Cristina Roman, Peter Arnett

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    • P0636 - Relationship of real-world brain atrophy to MS disability using icobrain: 4 centre pilot study (View Presentation)

      Keyword: Imaging

      Ai-Lan Nguyen, Dana Horakova, Eva Havrdova, Michael Barnett, Maria Pia Sormani, Elaine Lui, Frank Gaillard, Patricia Desmond, Hayden Prime, Mineesh Datta, Anneke Van Der Walt, Vilija Jokubaitis, Bianca Weinstock-Guttman, Marie D’hooghe, Guy Nagels, Vincent Van Pesch, Guy Laureys, Liesbeth Van Hijfte, Jeannette Lechner-Scott, Francesco Patti, Edgardo Cristiano, Juan Rojas, Diana Sima, Wim Van Hecke, Tomas Kalincik, Helmut Butzkueven

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    • P0637 - Relevance of NODDI to characterise in vivo the microstructural abnormalities of multiple sclerosis cortex and cortical lesions: a 3T study (View Presentation)

      Keyword: Imaging

      Paolo Preziosa, Elisabetta Pagani, Raffaello Bonacchi, Laura Cacciaguerra, Massimo Filippi, Maria A. Rocca

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    • P0638 - Role of Gadolinium-based contrast agents to detect subclinical disease activity in clinically stable patients in the Swiss MS Cohort Study (View Presentation)

      Keyword: Imaging

      Tim Sinnecker, Esther Ruberte, Özgür Yaldizli, Reza Rahmanzadeh, Riccardo Galbusera, Ramona-Alexandra Todea, Alessandro Cagol, Suvitha Subramaniam, Pascal Benkert, Stefanie Müller, Lutz Achtnichts, Jochen Vehoff, Giulio Disanto, Oliver Findling, Andrew Chan, Anke Salmen, Caroline Pot, Patrice Lalive, Chiara Zecca, Tobias Derfuss, Johanna Lieb, Ernst-Wilhelm Radue, Luca Remonda, Franca Wagner, Maria Vargas, Philippe Maeder, Emanuele Pravata, Johannes Weber, David Leppert, Ludwig Kappos, Claudio Gobbi, Cristina Granziera, Jens Würfel, Jens Kuhle

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    • P0639 - Sensorimotor cerebellar functional connectivity changes as compensatory  mechanisms of structural damage in patients with MS and no disability (View Presentation)

      Keyword: Imaging

      Silvia Tommasin, Viktoriia Iakovleva, Maria A. Rocca, Gioacchino Tedeschi, Nicola De Stefano, Carlo Pozzilli, Paola Zaratin, Massimo Filippi, Patrizia Pantano

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    • P0640 - Sensorimotor network dynamics predicts loss of upper and lower limb function in people with multiple sclerosis (View Presentation)

      Keyword: Imaging

      Myrte Strik, Anand Eijlers, Iris Dekker, Tommy Broeders, Linda Douw, Joep Killestein, Scott Kolbe, Jeroen Geurts, Menno Schoonheim

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    • P0641 - Serum neurofilament light chain levels are associated with poorer thalamic perfusion in multiple sclerosis: cross-sectional DSC-PWI study (View Presentation)

      Keyword: Imaging

      Dejan Jakimovski, Niels Bergsland, Michael Dwyer, Murali Ramanathan, Bianca Weinstock-Guttman, Robert Zivadinov

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    • P0642 - Spatial distribution of cortical lesions in multiple sclerosis correlates to clinical and cognitive decline (View Presentation)

      Keyword: Imaging

      Piet Bouman, Nhi Nguyen, Maureen Van Dam, Laura Jonkman, Hanneke Hulst, Jeroen Geurts, Martijn Steenwijk

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    • P0644 - Spinal cord atrophy in a primary progressive multiple sclerosis trial: improved sample size using GBSI (View Presentation)

      Keyword: Imaging

      Marcello Moccia, Nicola Valsecchi, Olga Ciccarelli, Ronald Van Schijndel, Frederik Barkhof, Ferran Prados

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    • P0645 - Spinal cord pathology in a large cohort of MS patients with different levels of disability and MS phenotypes (View Presentation)

      Keyword: Imaging

      Manuela Vaneckova, Tereza Hrnciarova, Jan Krasensky, Tomas Uher, Michaela Andelova, Eliska Hardubejova, Eva Kubala Havrdová, Lucie Friedova, Veronica Ravano, Bénédicte Maréchal, Tobias Kober, Dana Horakova

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    • P0646 - Structural constraints of functional connectivity drive cognitive impairment in the early stages of multiple sclerosis (View Presentation)

      Keyword: Imaging

      Ismail Koubiyr, Mathilde Deloire, Bruno Brochet, Pierre Besson, Julie Charré-Morin, Aurore Saubusse, Thomas Tourdias, Aurélie Ruet

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    • P0647 - Studying intralesional axonal damage in MS white matter lesions with diffusion MRI biophysical models (View Presentation)

      Keyword: Imaging

      Muhamed Barakovic, Reza Rahmanzadeh, Po-Jui Lu, Pietro Maggi, Martina Absinta, Francesco La Rosa, Merixtell Bach-Cuadra, Simona Schiavi, Alessandro Daducci, Pascal Sati, Daniel Reich, Jens Kuhle, Matthias Weigel, Ludwig Kappos, Cristina Granziera

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    • P0648 - The central vein sign as a biomarker for MS in the infratentorial brain (View Presentation)

      Keyword: Imaging

      María Gaitán, María Paday Formenti, Jorge Correale, Paulina Yañez

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    • P0649 - The Central Vein Sign discriminates multiple sclerosis from its radiological mimics in the clinical setting (View Presentation)

      Keyword: Imaging

      María Emilia Paday Formenti, Paulina Yañez, María Teresa Goicochea, María Virginia Pujol Lereis, Hernan Chaves, Jorge Correale, María Gaitán

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    • P0650 - The contribution of cortical lesions to fatigue  and depression in relapsing remitting multiple sclerosis. (View Presentation)

      Keyword: Imaging

      Rocco Capuano, Alvino Bisecco, Alessandro D'Ambrosio, Renato Docimo, Manuela Altieri, Mario Risi, Giuseppina Caiazzo, Teresa Cuomo, Mario Cirillo, Gioacchino Tedeschi, Antonio Gallo

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    • P0651 - The effects of amiloride, fluoxetine and riluzole over 96 weeks on metabolic markers of brain injury in secondary progressive multiple sclerosis. (View Presentation)

      Keyword: Imaging

      Nevin John, Bhavana Solanky, Floriana De Angelis, Jon Stutters, Ferran Prados, Anisha Doshi, Richard Parker, Christopher Weir, Alberto Calvi, Thomas Williams, Torben Schneider, Domenico Plantone, Anita Monteverdi, David Macmanus, Ian Marshall, Frederik Barkhof, Claudia Wheeler-Kingshott, Jeremy Chataway

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    • P0652 - The relationship among leptomeningeal enhancement clinical, radiological activity and cerebrospinal fluid markers (View Presentation)

      Keyword: Imaging

      Nicolò Bruschi, caterina Lapucci, Maria Cellerino, Giacomo Boffa, elvira Sbragia, Elisabetta Mancuso, Giacomo Rebella, francesco Tazza, Lucio Castellan, Matilde Inglese

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    • P0653 - The value of grey matter microglial activation measurement by TSPO-PET in predicting clinical disease progression in multiple sclerosis (View Presentation)

      Keyword: Imaging

      Olavi Misin, Markus Matilainen, Eero Rissanen, Marcus Sucksdorff, Laura Airas

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    • P0654 - Time course of hippocampal functional connectivity in relation with memory performances at the early stage of multiple sclerosis (View Presentation)

      Keyword: Imaging

      Ismail Koubiyr, Juliette Boscheron, Mathilde Deloire, Bruno Brochet, Julie Charré-Morin, Aurore Saubusse, Aurélie Ruet, Thomas Tourdias

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    • P0655 - Tissue destruction and blood-brain barrier breakdown in chronic-active vs. inactive MS lesions by 7T MP2RAGE and susceptibility MRI (View Presentation)

      Keyword: Imaging

      Sarah Lake, Seongjin Choi, Daniel Harrison

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    • P0656 - Unraveling deep grey matter atrophy, iron and myelin changes in Multiple Sclerosis (View Presentation)

      Keyword: Imaging

      Maria Petracca, Giuseppe Pontillo, Serena Monti, Mario Quarantelli, Chiara Criscuolo, Roberta Lanzillo, Enrico Tedeschi, Andrea Elefante, Vincenzo Brescia Morra, Sirio Cocozza, Giuseppe Palma, Arturo Brunetti

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    • P0657 - Utility of Gadolinium in Multiple Sclerosis Radiographic Monitoring (View Presentation)

      Keyword: Imaging

      Amanda Thuringer, Sharon Lynch

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    • P0658 - Vascular Disease Risk Factors in Multiple Sclerosis (View Presentation)

      Keyword: Imaging

      Vijayshree Yadav, Michael Lane, Allison Fryman, Frank Bittner, Manoj Sammi, Valerie Anderson, William Rooney

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    • P0659 - White matter tracts that overlap with hubs are preferentially protected against multiple sclerosis pathology (View Presentation)

      Keyword: Imaging

      Margareta Clarke, Derek Archer, Keejin Yoon, Richard Dortch, Seth Smith, Junzhong Xu, Gary Cutter, Francesca Bagnato

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    • P0660 - Yield and potential value of spinal cord MRI surveillance in treated relapsing multiple sclerosis   (View Presentation)

      Keyword: Imaging

      Cristina Valencia-Sanchez, Jonathan Carter, Dean Wingerchuk

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    • P0661 - A 164 second multi-format film successfully conveys the importance of early intervention in MS (View Presentation)

      Keyword: Internet and Social Media

      David Wilkie, Rod Middleton, James Cook, Richard Nicholas

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    • P0662 - How patients utilize online data sources to engage with the Multiple Sclerosis (MS) community and search for information on their condition (View Presentation)

      Keyword: Internet and Social Media

      Joanna White, Sandra Teoh, Simone Gabriele, Joseph Vindici

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    • P0663 - Real-time internet-based teleconsultations for neurological follow-up of patients with multiple sclerosis: an interim feasibility analysis (View Presentation)

      Keyword: Internet and Social Media

      Miguel D'Haeseleer, Nima Sadeghi, Piet Eelen, Corinne Cuvelier, Marie D'Hooghe, Guy Nagels, Katinka Van Gils, Jeroen Van Schependom

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    • P0664 - Smartphone based Symbol Digit Modalities Test reliably measures cognitive function in multiple sclerosis patients (View Presentation)

      Keyword: Internet and Social Media

      Linh Pham, Thomas Harris, Mihael Varosanec, Peter Kosa, Vanessa Morgan, Bibiana Bielekova



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    • P0665 - Social Listening: Digital Profile of the Multiple Sclerosis Patient in Mexico (View Presentation)

      Keyword: Internet and Social Media

      Fernanda Rodríguez, Miriam Jiménez, Diego Mireles Jacobo

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    • P0666 - Telemedicine in/outside the pandemic: a survey about satisfaction of this tool in a cohort of multiple sclerosis patients and their neurologists (View Presentation)

      Keyword: Internet and Social Media

      Lucia Moiola, Maria Di Cristinzi, Simone Guerrieri, Agostino Nozzolillo, Mario Orrico, Stefano Gelibter, Luca Bosco, Chiara Zanetta, Francesca Sangalli, Massimo Filippi

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    • P0667 - The Dutch MS Patient Voice Survey: The search for information. (View Presentation)

      Keyword: Internet and Social Media

      jan Muis, chris Schouten, Ellemieke De Wolf, Leonoor Avis, Lianne Hoeijmakers, Anouk Buurman

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    • P0668 - Understanding Multiple Sclerosis Massive Open Online Course: Closing The Gap On Information Asymmetry (View Presentation)

      Keyword: Internet and Social Media

      Suzi Claflin, Bruce Taylor, Julie Campbell

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    • P0669 - Using WebEx Technology to Increase Knowledge and Awareness About Multiple Sclerosis via Documentary Film “When We Walk” as an Educational Intervention (View Presentation)

      Keyword: Internet and Social Media

      Suzanne Boyd, Suzanne Jones, Shelby Veri

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    • P0670 - Ecological and functional alterations of the gut microbiome in different stages of multiple sclerosis (View Presentation)

      Keyword: Microbiome

      Daiki Takewaki, Wataru Suda, Wakiro Sato, Lena Takayasu, Sachiko Miyake, Masahira Hattori, Takashi Yamamura

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    • P0671 - Exploring the gut microbiome in multiple sclerosis via the international MS Microbiome Study (iMSMS) (View Presentation)

      Keyword: Microbiome

      Xiaoyuan Zhou, Sneha Singh, Myra Mendoza, Ryan Baumann, James Landefeld, Patrizia Casaccia, Ilana Katz Sand, Zongqi Xia, Howard Weiner, Tanuja Chitnis, Siddharthan Chandran, Peter Connick, David Oteagui, Tamara Castillo-Trivino, Stacy Caillier, Adam Santaniello, Gail Ackermann, Greg Humphrey, laura Negrotto, Mauricio Farez, Reinhard Hohlfeld, Anne-Katrin Pröbstel, Xiaoming Jia, Jennifer Graves, Amit Bar-Or, Harmut Wekerle, Jorge Oksenberg, Timothy West, Jorge Correale, Bruce Cree, Stephen Hauser, Rob Knight, Sergio Baranzini

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    • P0672 - Human commensal Prevotella histicola ameliorates disease in an animal model of multiple sclerosis  as effectively as interferon-beta (View Presentation)

      Keyword: Microbiome

      Shailesh Shahi, Samantha Jensen, Alexandra Murra, Katherine Gibson-Corley, Nitin Karandikar, Joseph Murray, Ashutosh Mangalam

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    • P0673 - Induction of human IL-10 and protection against murine EAE by a manufactured human gut derived microflora antigen  (View Presentation)

      Keyword: Microbiome

      javier Ochoa-Reparaz, lore Kasper

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    • P0674 - “Lactobacillus species differentially alter CNS autoimmunity via distinct immunomodulatory genomic loci and modulation of gut microbial composition.” (View Presentation)

      Keyword: Microbiome

      Theresa Montgomery, Korin Eckstrom, Axel Kunstner, Josephine Kennedy, Rachel Culp-Hill, Angelo D’alessandro, Hauke Busch, Matthew Wargo, Dimitry Krementsov

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    • P0675 - Multi-OMICS of the host-gut microbiome dynamics in multiple sclerosis (View Presentation)

      Keyword: Microbiome

      Laura Ghezzi, Claudia Cantoni, Alberto Locca, Pamela Newland, Amy E. Lovett-Racke, Yanjiao Zhou, LAURA Piccio

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    • P0676 - Ocrelizumab impacts IgA coating of immunomodulatory gut bacteria in multiple sclerosis patients (View Presentation)

      Keyword: Microbiome

      Guneet Janda, Inessa Cohen, William Ruff, Erin Longbrake

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    • P0677 - Possible association between miRNAs and gut microbiota in pathogenesis of Multiple sclerosis (View Presentation)

      Keyword: Microbiome

      Mallahalli Manu, Takashi Yamamura, Hirohiko Hohjoh, Wakiro Sato, Shinji Oki

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    • P0678 - Selected Clostridia strains increase responses related to interferon beta signaling and butyrate levels in experimental autoimmune encephalomyelitis (View Presentation)

      Keyword: Microbiome

      Laura Calvo-Barreiro, Herena Eixarch, Thais Cornejo, Mireia Castillo, Leire Mestre, Carmen Guaza, Juan José González López, Xavier Montalban, Carmen Espejo

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    • P0679 - The gut microbiota: a case-control study of children with multiple sclerosis, monophasic acquired demyelinating syndromes and unaffected controls (View Presentation)

      Keyword: Microbiome

      Helen Tremlett, Feng Zhu, Douglas L Arnold, Amit Bar-Or, Charles Bernstein, Jessica Forbes, Morag Graham, Janace Hart, Natalie Knox, Ruth Ann Marrie, Ali Mirza, Julia O’mahony, Gary Van Domselaar, E. Ann Yeh, Yinshan Zhao, Brenda Banwell, Emmanuelle Waubant

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    • P0680 - The role of gut microbiota in the Egyptian relapsing remitting multiple sclerosis patients. (View Presentation)

      Keyword: Microbiome

      Sherein Elgendy, Enas Daef, Shereen Mohammed, Mohamed El-Mokhtar, Hebat.Allah Hassan, Rawan El.hameed, Eman Khedr, Ahmed Nasreldein

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    • P0681 - A severe case of tetraparesis with conus involvement in neuromyelitis optica spectrum disorder (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Amy Safadi, Cory Myers, Nancy Hu, Benjamin Osborne

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    • P0682 - Aggressive and fulminant course of Anti-myelin oligodendrocyte glycoprotein antibody associated disease in a solid organ receptor (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      guido david Vazquez, Juan Blas Couto, Carla Bolaño, franco Appiani, santiago Claverie, jesica Pszenyckyj, Vladimiro Sinay, Adriana Carra

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    • P0683 - Altered resting state dynamic functional connectivity of precuneus contributes to cognition and depression in neuromyelitis optica spectrum disorders (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Laura Cacciaguerra, Damiano Mistri, Paola Valsasina, Vittorio Martinelli, Massimo Filippi, Maria A. Rocca

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    • P0684 - Anti-IL-6 receptor antibody prevents blood-brain barrier disruption in mice with experimental autoimmune encephalomyelitis (EAE) (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Kenichi Serizawa, Shota Miyake, Haruna Tomizawa-Shinohara, Kenji Yogo, Yoshihiro Matsumoto

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    • P0685 - AQP4-IgG and MOG-IgG related optic neuritis – prevalence, optical coherence tomography findings, visual outcomes: systematic review and meta-analysis (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Angeliki Filippatou, Loulwah Mukharesh, Shiv Saidha, Peter Calabresi, Elias Sotirchos

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    • P0686 - Aquaporin-4 antibody seroreversion in patients with neuromyelitis optica spectrum disorder treated with rituximab. (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Kottil Rammohan, Leticia Tornes, Silvia Delgado, Neeta Garg, Crystal Dixon, Melissa Ortega, Jeffrey Hernandez, Nicole Hughes, Maria Botero, Micheline McCarthy

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    • P0687 - Aquaporin-4 neuromyelitis optica spectrum disorder in a 5-year-old girl presenting with neuropsychiatric symptoms (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Clara Chow Haws, Ram Narayan

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    • P0688 - Area postrema syndrome and longitudinally extensive transverse myelitis in a patient with prostatic adenocarcinoma and Aquaporin-4 antibodies. (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Alessandro Dinoto, Antonio Bosco, Arianna Sartori, Marta Cheli, Giulia Bellavita, Fulvio Pasquin, Alessio Bratina, Paolo Manganotti

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    • P0689 - Autoimmune comorbidity increases healthcare cost burden in patients with NMOSD in the United States: a retrospective commercial claims analysis   (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Christina Reyeswright, Alex Exuzides, Daniel Sheinson, Paris Sidiropoulos, Shervin Gholizadeh, Fabio Magrini, Andy Surinach, Lawrence Cook, Craig Meyer, Michael Yeaman

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    • P0690 - Autologous hematopoietic stem cell transplantation in a pediatric patient with aquaporin-4 neuromyelitis optica spectrum disorder (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Tuba Khan, Cynthia Wang

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    • P0691 - Autologous Hematopoietic Stem Cell Transplantation in Neuromyelitis Optica – Year 5 Update (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Jodie Burton, Jan Storek, Fiona Costello, Peter Duggan, Luanne Metz

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    • P0692 - Benefit of eculizumab for a broad range of patients with aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder: findings from PREVENT (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Kazuo Fujihara, Achim Berthele, Ho Jin Kim, Michael Levy, Ichiro Nakashima, Celia Oreja-Guevara, Jacqueline Palace, Sean Pittock, Murat Terzi, Natalia Totolyan, Shanthi Viswanathan, Kai-Chen Wang, Amy Pace, Marcus Yountz, Larisa Miller, Imran Tanvir, Róisín Armstrong, Dean Wingerchuk

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    • P0693 - Brainstem and cerebellar involvement in MOG-IgG Associated Disorder versus Aquaporin-4-IgG and Multiple Sclerosis (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Samantha Banks, Padraig Morris, John Chen, Sean Pittock, Elia Sechi, Amy Kunchok, Jan-Mandelt Tillema, James Fryer, Brian Weinshenker, Karl Krecke, Alfonso Lopez-Chiriboga, Adam Nguyen, Tammy Greenwood, Claudia Lucchinetti, Steven Messina, Eoin Flanagan

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    • P0694 - Burden of autoimmune comorbidity in patients with NMOSD in the United States revealed by retrospective commercial claims analysis (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Christina Reyeswright, Alex Exuzides, Daniel Sheinson, Paris Sidiropoulos, Shervin Gholizadeh, Fabio Magrini, Andy Surinach, Lawrence Cook, Craig Meyer, Michael Yeaman

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    • P0695 - Burden of disease in patients with neuromyelitis optica spectrum disorder: insights from the CIRCLES study cohort (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Minying Royston, Imran Tanvir, John Rose, Kateyln Lewis, Chella Palmer, Jennifer Sinnott, Anna Jolley, Jacinta Behne, Megan Behne, Terrence Blaschke, Terry Smith, Olivier Morteau, Lawrence Cook, Adrian Kielhorn, Michael Yeaman, Stacy Gallogly

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    • P0696 - Characteristics of Myelin Oligodendrocyte Glycoprotein Antibody Positive Children with Demyelinating Disorders (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Janet Chong, Allysa Lui, Aaron Abrams, Eoin Flanagan, Kristen Krysko, Carla Francisco, Alice Rutatangwa, Emmanuelle Waubant, Amin Ziaei

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    • P0697 - Child with MOG antibodies, synringomyelia and MRI mimicking Langerhansian hystiocytosis (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Samira Hatteb, Neyla Mesbahi, Smail Daoudi

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    • P0698 - Clinical and MRI correlates of autonomic dysfunction in neuromyelitis optica spectrum disorder (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Ju-Hong Min, Soonwook Kwon, Ye Sel Kim, Juhyeon Kim, Huimei Kwon, Jong Hwa Shin, Byoung Joon Kim

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    • P0699 - Clinical and radiological features of a hospital cohort of Neuromyelitis optica. (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Gary Alvarez Bravo, Lluís Ramió I Torrentà, René Robles Cedeño, Ester Quintana, Jordi Gich, Marina González

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    • P0700 - Clinical characteristics of neuromyelitis optica spectrum disorder and multiple sclerosis in Iranian pediatric patients (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Mahdi Barzegar, Omid Mirmosayyeb, Vahid Shaygannejad

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    • P0701 - Clinical characteristics of Neuromyelitis optica spectrum disorder Peruvian patients: a government-run tertiary level neurological center cohort (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      César Caparó-Zamalloa, Sheila Castro-Suarez, Wilfor Aguirre-Quispe, María Meza-Vega

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    • P0702 - Clinical characteristics of neuromyelitis optica spectrum disorders in a Spanish population. (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Juan Diego Guerra Hiraldo, Rocío López Ruiz, Félix Sánchez Fernández, Julio Dotor García-Soto, Juan luis Ruiz-Peña, Maria Dolores Páramo Camino, Guillermo Navarro Mascarell, Sara Eichau Madueño

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    • P0703 - Clinical, radiological features and management of twenty patients diagnosed with anti-MOG demyelinating syndrome in a tertiary referral centre. (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Maria Gaughan, Cormac O'Brien, Christopher McGuigan

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    • P0704 - Cortical involvement  in MOG IgG–positive patients : a multicenter MRI study (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Dimitrios Tzanetakos, John Tzartos, Aigli Vakrakou, Marianthi Breza, Maria Eleftheria Evangelopoulos, Georgios Koutsis, Maria Anagnostouli, Georgios Velonakis, Eirini Pantou, Ioannis Markakis, Dimitra Papadimitriou, Efstratios Karavasilis, Panagiotis Toulas, Leonidas Stefanis, Constantinos Kilidireas

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    • P0705 - Cost of illness for patients with NMOSD and nonautoimmune disease estimated from claims databases in the United States   (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Christina Reyeswright, Alex Exuzides, Daniel Sheinson, Paris Sidiropoulos, Shervin Gholizadeh, Fabio Magrini, Andy Surinach, Lawrence Cook, Craig Meyer, Michael Yeaman

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    • P0706 - Cost of neuromyelitis optica spectrum disorder in US clinical practice (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Adrian Kielhorn, Minying Royston, Derek Weycker, Melody Shaff, Linnea Houde, Imran Tanvir, Michael Levy, Stacy Gallogly

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    • P0707 - Costs and health-related quality of life in patients with neuromyelitis optica spectrum disorder and MOG-antibody associated disease (CHANCENMO-Study) (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Martin W. Hümmert, Louisa Schöppe, Judith Bellmann-Strobl, Nadja Siebert, Friedemann Paul, Ankelien Duchow, Hanna Pellkofer, Tania Kuempfel, Joachim Havla, Sven Jarius, Brigitte Wildemann, Florian Then Bergh, Marc Pawlitzki, Luisa Klotz, Ingo Kleiter, Martin Stangel, Stefan Gingele, Martin Weber, Jürgen H. Faiss, Refik Pul, Annette Walter, Uwe Zettl, Makbule Senel, Jan-Patrick Stellmann, Vivien Häußler, Kerstin Hellwig, Ilya Ayzenberg, Orhan Aktas, Marius Ringelstein, Olivia Schreiber-Katz, Corinna Trebst

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    • P0708 - Differential MRI biomarkers between MOGAD, AQP4-NMOSD and RRMS: a MAGNIMS multicenter study (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Rosa Cortese, Marco Battaglini, Ferran Prados, Alessia Bianchi, Lukas Haider, Ludwig Kappos, Özgür Yaldizli, Jannis Müller, Carsten Lukas, Barbara Bellenberg, Ruth Schneider, Sergiu Groppa, Matthias Grothe, Yaou Liu, Yunyun Duan, Sara Llufriu, Maria Sepulveda, Georgina Arrambide, Jaume Sastre-Garriga, Alex Rovira, Friedemann Paul, Jens Wuerfel, Anu Jacob, Frederik Barkhof, Nicola De Stefano, Olga Ciccarelli

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    • P0709 - Discontinuation of therapy may lead to an increased risk of relapse in patients with neuromyelitis optica even after 5 years of remission (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Su-Hyun Kim, Hyunmin Jang, Na Young Park, Yeseul Kim, So-Yeon Kim, Min Young Lee, Jae-Won Hyun, Ho Jin Kim

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    • P0711 - Efficacy of satralizumab in neuromyelitis optica spectrum disorder (NMOSD): Results from open-label extension periods of SAkuraSky and SAkuraStar (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Enya Lucas, Benjamin Greenberg, Jeffrey Bennett, Jérôme De Seze, Ingo Kleiter, Lech Szczechowski, Takashi Yamamura, Edward Fox, Brian Weinshenker, H.-Christian Von Büdingen, Daniela Stokmaier, Gaelle Klingelschmitt, Kristina Weber, Cristina Costantino, Anthony Traboulsee

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    • P0712 - Estimating the cost of illness for patients with neuromyelitis optica spectrum disorder from US commercial claims (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Christina Reyeswright, Alex Exuzides, Daniel Sheinson, Paris Sidiropoulos, Shervin Gholizadeh, Andy Surinach, Lawrence Cook, Craig Meyer, Michael Yeaman

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    • P0713 - Evidence of subclinical quantitative retinal layer abnormalities in aquaporin-4-IgG seropositive NMOSD (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Angeliki Filippatou, Eleni Vasileiou, Yufan He, Kathryn Fitzgerald, Grigorios Kalaitzidis, Jeffrey Lambe, Maureen Mealy, Michael Levy, Yihao Liu, Jerry Prince, Ellen Mowry, Shiv Saidha, Peter Calabresi, Elias Sotirchos

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    • P0714 - Experience with subcutaneous Tocilizumab in Neuromyelitis Optica spectrum disorders during SARS-CoV-2 pandemic (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Clara Aguirre, Virginia Meca-Lallana, Beatriz Del Río, Jose Vivancos

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    • P0715 - Failure of Age-Expected Brain Growth in Children with ADEM is Independent of MOG-Antibody Status (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Frederik Bartels, Birgit Baumgartner, Graham Cooper, Astrid Blaschek, Eva Wendel, Klaus Marquardt, Michael Karenfort, Matthias Baumann, Robert Cleaveland, Andreas Wegener-Panzer, Steffen Leiz, Michela Salandin, Peter Krieg, Tobias Reindl, Markus Reindl, Carsten Finke, Kevin Rostásy

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    • P0716 - Fall frequency and risk factors in patients with neuromyelitis optica spectrum disorder (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Mahdi Barzegar, Omid Mirmosayyeb, Reyhane Azarbayejani, Serge Brand, Alireza Afshari-Safavi, Vahid Shaygannejad, Dean Sadeghi Bahmani

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    • P0717 - Frequency of comorbidities in Neuromyelitis Optica spectrum disorder (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Mahdi Barzegar, Omid Mirmosayyeb, Nasim Nehzat, Saeed Vaheb, Vahid Shaygannejad, Nasrin Asgari

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    • P0718 - Impact of relapse on disability and quality of life in patients with neuromyelitis optica spectrum disorder: findings from the Phase 3 PREVENT study (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Achim Berthele, Michael Levy, Dean Wingerchuk, Celia Oreja-Guevara, Ichiro Nakashima, Ho Jin Kim, Kai-Chen Wang, Kazuo Fujihara, Natalia Totolyan, Sean Pittock, Shulian Shang, Adrian Kielhorn, Minying Royston, Guido Sabatella, Jacqueline Palace, Stacy Gallogly

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    • P0719 - Incidence of NMOSD relapses and seasonal influence in an equatorial country cohort  (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Lilliana Giraldo, Carolina Restrepo-Aristizábal, Cesar Franco, Jose Tobon, Jose Asencio, Maria Zuluaga Rodas

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    • P0720 - Incidence of relapses in NMOSD patients under immunosupressive therapies in Argentina: observational study from RelevarEM. (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Veronica Tkachuk, Marina Alonso Serena, Maria Eugenia Balbuena, Pablo Lopez, Juan Pettinicchi, Agustin Pappolla, Jimena Miguez, Liliana Patrucco, Edgardo Cristiano, Carlos Vrech, Susana Liwacki, Jorge Correale, Mariano Marrodan, María Gaitán, Marcela Fiol, Laura Negrotto, María Ysrraelit, Marcos Burgos, Felisa Leguizamon, Darío Tavolini, Norma Deri, Carolina Mainella, Geraldine Luetic, Patricio Blaya, Javier Hryb, Maria Menichini, Amelia Alves Pinheiro, Pedro Nofal, Gisela Zanga, Andres Barboza, Ivan Martos, Luciana Lazaro, Emanuel Silva, Santiago Bestoso, Maria Eugenia Fracaro, Adriana Carra, orlando Garcea, Nora Fernandez Liguori, alejandro Caride, Juan Rojas, Edgar Carnero Contentti

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    • P0721 - Infection rates with satralizumab in patients with neuromyelitis optica spectrum disorder (NMOSD): results from the phase 3 SAkura studies (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Enya Lucas, Brian Weinshenker, Kathleen Blondeau, Xiujing Kou, Carole Marcillat, Kristina Weber, Benjamin Greenberg

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    • P0722 - Inter-attack astrocyte damage in NMOSD – does it exist? : Longitudinal analysis of serum GFAP (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Jae-Won Hyun, Yeseul Kim, So-Yeon Kim, Min Young Lee, Su-Hyun Kim, Ho Jin Kim

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    • P0723 - Internuclear Ophthalmoplegia Characterizes Multiple Sclerosis Rather Than Neuromyelitis Optica Spectrum Disease  (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Mahmoud Hamza, Basheer Alas, Michael Robers, Lilyana Amezcua, Kimberly Gokoffski

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    • P0724 - Isolated recurrent non longitudinally extensive myelitis in two MOG positive patients (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Gabriel Valero López, Ester Carreón Guarnizo, Maria de la Paz Moreno Arjona, Rocio Hernandez Clares, Moisés Morales De La Prida, Maria Canovas Iniesta, Francisca Iniesta Martinez, Ana Morales Ortiz, José Meca-Lallana

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    • P0725 - Life After Tetra Hit: Anti-Nmdar Encephalitis After HSV Encephalitis In a NMOSD Coexistent With Sjogren’s Syndrome Patient (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Cansu Ayvacioglu Cagan, Nazire Pinar Acar Ozen, Aslı Tuncer

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    • P0726 - Longitudinally extensive transverse myelitis and NMOSD associated with dengue infection: a case report and systematic review of cases (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Jacynthe Comtois, Carlos R. Camara-Lemarroy, Jean K. Mah, Colleen Curtis, Susan Kuhn, Marvin Braun, Raymond Tellier, Jodie Burton

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    • P0727 - Long-term efficacy and safety of eculizumab in AQP4+ neuromyelitis optica spectrum disorder (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Dean Wingerchuk, Achim Berthele, Kazuo Fujihara, Celia Oreja-Guevara, Ho Jin Kim, Michael Levy, Ichiro Nakashima, Jacqueline Palace, Shulian Shang, Marcus Yountz, Larisa Miller, Sean Pittock

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    • P0728 - Long-term follow-up of rituximab treatment in 10 Spanish patients with neuromyelitis optica spectrum disorder. (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Juan Diego Guerra Hiraldo, Rocío López Ruiz, Julio Dotor García-Soto, Maria Dolores Páramo Camino, Juan luis Ruiz-Peña, Guillermo Navarro Mascarell, Sara Eichau Madueño

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    • P0729 - MOG antibody disease: treatment and disability data from a Canadian cohort (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Helen Cross, Virginia Devonshire, Robert Carruthers, Ana Luiza Sayao, Alice Schabas, Nathalie Ackermans, Marvin Fritzler, Patrick Waters, Anthony Traboulsee

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    • P0730 - More rapid recovery and improved outcome with early steroid therapy in MOG-IgG associated  optic neuritis (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      John Chen, Eoin Flanagan, M. Bhatti, Sepideh Jamali, Amy Kunchok, Eric Eggenberger, Marie Acierno, Anthony Arnold, Eduardo Seleme, Alvaro Meija-Vergara, Heather Moss, Tanyatuth Padungkiatsagul, Hadas Stiebel-Kalish, Sean Pittock

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    • P0731 - Multiple sclerosis and NMOSD testing and treatment availability in Latin America (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Juan Rojas, Fernando Gracia, Liliana Patrucco, Edgardo Cristiano

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    • P0732 - Neuromyelitis Optica Spectrum Disorder in the U.S. Active-Duty Military (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Nathan Tagg, Keith Groshans, David Horvat, Jonathan Galli, Stacey Clardy

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    • P0733 - Neuromyelitis Optica Spectrum Disorder with Interstitial Pneumonia as the First Episode: A Case Report (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      NIKOLAOS Fakas, Alexandra Akrivaki, Georgios Papadopoulos, Victor Kotzamanis, Dimitra Tzavella, Evangellos Sfikas, Sokratis Triantafyllou, Panagiotis Apostolopoulos

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    • P0734 - Neuromyelitis Optica Spectrum Disorder With Interstitial Pneumonia as the First Episode: A Case Report (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Georgios Papadopoulos, NIKOLAOS Fakas, Alexandra Akrivaki



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    • P0735 - Neuromyelitis Optica spectrum disorder, characterization of a population in a specialized center in Colombia (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Catalina Orozco Gonzalez, Maria Zuluaga Rodas, Paola Ortiz-Salas, Jhyld Camacho-Barbosa, Jorge Donado-Gómez, Natalia Duque-Zapata

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    • P0736 - NMOSD incidence and prevalence estimates in Western Mexico  (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Fernando Cortés-Enríquez, Ricardo Valdivia-Tangarife, Mario Mireles-Ramírez, Nayeli Sanchez-Rosales, José Hernandez-Priego, Miguel Macías-Islas

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    • P0737 - Non-compressive myelopathies (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      SAMIRA Er-Riouiche



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    • P0738 - Onset of neuromyelitis optica spectrum disorder with limbic encephalitis or coexistence of those conditions in a single patient? (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Zuleyma Toledo-Nieves, Irena Dujmovic-Basuroski

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    • P0739 - Optic chiasm involvement in MS, aquaporin-4 antibody-positive NMOSD, and MOG antibody-associated disease (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Alessia Bianchi, Rosa Cortese, Ferran Prados, Carmen Tur, Baris Kanber, Marios Yiannakas, Floriana De Angelis, Lise Magnollay, Anu Jacob, Wallace Brownlee, Anand Trip, Richard Nicholas, Yael Hacohen, Frederik Barkhof, Olga Ciccarelli, Ahmed Toosy

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    • P0740 - Optic neuropathy in Anti-MOG antibody associated disorders (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      salma Laassila, SIHAM Bouchal



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    • P0741 - Pain, depression and quality of life in adults with MOG-antibody associated disease (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Susanna Asseyer, Eugenia Henke, Corinna Trebst, Martin W. Hümmert, Brigitte Wildemann, Sven Jarius, Marius Ringelstein, Orhan Aktas, Marc Pawlitzki, Melanie Korsen, Luisa Klotz, Nadja Siebert, Klemens Ruprecht, Judith Bellmann-Strobl, Klaus-Dieter Wernecke, Vivien Häußler, Joachim Havla, Anna Gahlen, Ralf Gold, Friedemann Paul, Ingo Kleiter, Ilya Ayzenberg

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    • P0742 - Pain, depression and quality of life in NMOSD: a cross-sectional study of 166 AQP4-antibody seropositive patients in Europe (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Ilya Ayzenberg, Daniel Richter, Eugenia Henke, Susanna Asseyer, Friedemann Paul, Corinna Trebst, Martin W. Hümmert, Tania Kümpfel, Joachim Havla, Marius Ringelstein, Orhan Aktas, Sven Jarius, Brigitte Wildemann, Vivien Häußler, Jan-Patrick Stellmann, Makbule Senel, Luisa Klotz, Hannah Pellkoffer, Martin Weber, Marc Pawlitzki, Paulus Rommer, Achim Berthele, Kerstin Hellwig, Ralf Gold, Ingo Kleiter

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    • P0743 - Patients with neuromyelitis optica spectrum disorder who experience relapses take more chronic pain medication (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Stacey Clardy, Robert Kadish, Imran Tanvir, Tavan Parker, Joseph Biskupiak, Adrian Kielhorn, Minying Royston, Stacy Gallogly

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    • P0744 - Posterior Reversible Encephalopathy Syndrome Complicating Plasmapheresis In Neuromyelitis Optica  (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      GINA Perez, Nidhiben Anadani

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    • P0745 - Predictors of Diagnosis With A First Presenting Symptom Of Optic Neuritis (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Mhd Omar Subei, Alessandro Serra, Michael Morgan, Hesham Abboud

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    • P0746 - Purinergic inhibitors protect astrocytes from aquaporin-4 antibody-mediated complement-dependent death (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Sudhakar Kalluri, Rajneesh Srivastava, Selin Kenet, Goutam Tanti, Jeffrey Bennett, Klaus Dornmair, Thomas Misgeld, Bernhard Hemmer, Marina Herwerth

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    • P0747 - Rapid improvement in neurologic symptoms of neuromyelitis optica spectrum disorder with eculizumab monotherapy: Case report (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Patricia Pagnotta, David Honeycutt

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    • P0748 - Relapse-associated visual impairment and disability in patients with neuromyelitis optica spectrum disorder (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Robert Kadish, Stacey Clardy, Minying Royston, Imran Tanvir, Tavan Parker, Joseph Biskupiak, Adrian Kielhorn, Stacy Gallogly

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    • P0749 - Relapses and associated healthcare resource utilization among patients with neuromyelitis optica spectrum disorder in US clinical practice (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Minying Royston, Adrian Kielhorn, Derek Weycker, Melody Shaff, Linnea Houde, Imran Tanvir, Michael Levy, Stacy Gallogly

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    • P0750 - Relation between helicobacter pylori infection and double seronegative neuromyelitis optica spectrum disorder (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Mahdi Barzegar, Hosein Nouri, Geir Bjørklund, Omid Mirmosayyeb, Hossein Motedayyen, Vahid Shaygannejad

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    • P0751 - Risk factors related to relapse after first immunosuppressive treatment in patients with neuromyelitis optica spectrum disorders. (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Fernando Morales-Ramírez, Irene Treviño-Frenk, Gladys Barriga-Maldonado

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    • P0752 - Safety of eculizumab in NMOSD and MG – analysis of the phase 3 studies PREVENT and REGAIN and their extensions (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Renato Mantegazza, Todd Levine, Celia Oreja-Guevara, Cynthia Carrillo-Infante, Eva Laudon-Meyer, Shulian Shang, Sean Pittock, James Howard

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    • P0753 - Safety of satralizumab based on pooled data from phase 3 studies in patients with neuromyelitis optica spectrum disorder (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Enya Lucas, Benjamin Greenberg, Jérôme De Seze, Edward Fox, Albert Saiz, Takashi Yamamura, Michael Yeaman, Carole Marcillat, Xiujing Kou, Kristina Weber, Kathleen Blondeau, Brian Weinshenker

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    • P0754 - Satralizumab in first incident treatment-naïve AQP4-IgG seropositive NMOSD patients enrolled to SAkuraStar: a case series (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Enya Lucas, Jacqueline Palace, Jeffrey Bennett, Daniela Stokmaier, H.-Christian Von Büdingen, Gaelle Klingelschmitt, Anthony Traboulsee

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    • P0755 - Study of Sleep Abnormalities in patients with Neuromyelitis Optica Spectrum Disorder – AQP-4, Seronegative NMOSD and MOG associated disorders (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Abel Oommen, Ravi Yadav, Netravathi M

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    • P0756 - Subcortical structures shape analysis of fatigue in neuromyelitis optica spectrum disorder (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Jin Myoung Seok, Doo-hwan Son, Jong Hwa Shin, Eun Bin Cho, Byoung Joon Kim, Joon-Kyung Seong, Ju-Hong Min

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    • P0757 - The neutrophil-to-lymphocyte ratio in aquaporin-4-positive NMOSD patients: A Latin American multicenter study (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Edgar Carnero Contentti, Juan Criniti, Pablo Lopez, Juan Pettinicchi, Edgardo Cristiano, Jimena Miguez, Edgar Patricio Correa-Diaz, Marcelo Oswaldo Alvarez Pucha, Joselyn Miño Zambrano, Enrique Gomez Figueroa, Guillermo Garcia-Delgado, Veronica Rivas-Alonso, Jose Flores-Rivera, Veronica Tkachuk, alejandro Caride, Juan Rojas

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    • P0758 - The role of peripheral autoreactive antibodies in initiation and propagation of central nervous system demyelinating disorders (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Marie Freier, Silke Häusser-Kinzel, Martin Weber

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    • P0759 - Treatment patterns in patients with neuromyelitis optica spectrum disorder (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Enya Lucas, Julie Mouchet, Tim Spelman, Cristina Costantino, Thomas Kalincik, Petra Nytrova, Vahid Shaygannejad, Francesco Patti, Raed Alroughani, Murat Terzi, Serkan Ozakbas, Recai Turkoglu, Jagannadha Avasarala, Pamela McCombe, Magdolna Simo, Franco Granella, Jyh Yung Hor, Helmut Butzkueven

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    • P0760 - Tumefactive demyelination following rituximab in an anti-MOG positive NMOSD patient: evidence of T-cell and NK-cell involvement (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Marianthi Breza, John Tzartos, Nikolaos Paschalidis, Dimitrios Tzanetakos, Maria Eleftheria Evangelopoulos, Georgios Koutsis, Katerina Karagiorgou, Aigli Vakrakou, Eleni Strataki, Georgios Velonakis, Vily Panoutsakopoulou, Maria Anagnostouli, Leonidas Stefanis, Constantinos Kilidireas

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    • P0761 - What is seronegative neuromyelitis optica spectrum disorder? (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Emily Gibbons, Giovanna Campagna, Karen O'Connell, Tianrong Yeo, Daniel Whittam, Maria Leite, Jacqueline Palace, Anu Jacob, Saif Huda

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    • P0762 - What percentage of AQP4-Ab-negative NMOSD patients are MOG-Ab positive? A study from the Argentinean multiple sclerosis registry (RelevarEM) (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Edgar Carnero Contentti, Pablo Lopez, Juan Pettinicchi, Agustin Pappolla, Jimena Miguez, Liliana Patrucco, Edgardo Cristiano, Carlos Vrech, Veronica Tkachuk, Susana Liwacki, Jorge Correale, Mariano Marrodan, María Gaitán, Marcela Fiol, Laura Negrotto, María Ysrraelit, Marcos Burgos, Felisa Leguizamon, Darío Tavolini, Norma Deri, Maria Eugenia Balbuena, Carolina Mainella, Geraldine Luetic, Patricio Blaya, Javier Hryb, Maria Menichini, Amelia Alves Pinheiro, Pedro Nofal, Gisela Zanga, Andres Barboza, Ivan Martos, Luciana Lazaro, Emanuel Silva, Santiago Bestoso, Maria Eugenia Fracaro, Adriana Carra, orlando Garcea, Nora Fernandez Liguori, Marina Alonso Serena, alejandro Caride, Juan Rojas

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    • P0763 - A longitudinal study validating the optical coherence tomography inter-eye difference as a robust diagnostic test in multiple sclerosis (View Presentation)

      Keyword: Neuro-Ophthalmology

      Jenny Nij Bijvank, Bernard Uitdehaag, Axel Petzold

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    • P0764 - A prognostically relevant functional-structural relationship in acute optic neuritis (View Presentation)

      Keyword: Neuro-Ophthalmology

      Iris Kleerekooper, Shaun Leo, Indran Davagnanam, Lana Del Porto, Jose Manuel Guajardo, Laura Dell'Arti, Anthony Robson, S Anand Trip, Graham Holder, Gordon Plant, Axel Petzold

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    • P0765 - CRION versus Atypical MOG in a 61 Year-Old Woman (View Presentation)

      Keyword: Neuro-Ophthalmology

      Jodie Burton, Fiona Costello

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    • P0766 - Demographics of multiple sclerosis associated uveitis at Moorfields Eye Hospital (View Presentation)

      Keyword: Neuro-Ophthalmology

      Thomas Taylor, Josh Luis, Ruth Dobson, Harry Petrushkin

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    • P0767 - Increase Sensitivity in Detecting Neurodegeneration in Multiple Sclerosis: a Voxel-Based Morphometry Study with Optical Coherence Tomography  (View Presentation)

      Keyword: Neuro-Ophthalmology

      Su-Chun Huang, Marco Pisa, Simone Guerrieri, Gloria Dalla Costa, Federica Esposito, Letizia Leocani

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    • P0768 - Optical Coherence Tomography and unconventional neuro-ophthalmological evaluation of patients with Multiple Sclerosis (View Presentation)

      Keyword: Neuro-Ophthalmology

      Leila Cohen, Maria Barbara Eizaguirre, Ricardo Alonso, Cecilia Pita, Dolores Gonzalez Moron, orlando Garcea, Berenice Silva

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    • P0769 - Saccadic eye movements reflect functional connectivity of the oculomotor brain network in MS patients (View Presentation)

      Keyword: Neuro-Ophthalmology

      Jenny Nij Bijvank, E. Strijbis, I. Nauta, Shanna Kulik, L. Balk, Cornelis Stam, Arjan Hillebrand, Jeroen Geurts, Bernard Uitdehaag, L. Van Rijn, Axel Petzold, Menno Schoonheim

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    • P0770 - Serum neurofilaments predict recovery after acute optic neuritis (View Presentation)

      Keyword: Neuro-Ophthalmology

      Gloria Dalla Costa, Marco Pisa, Lorena Fabbella, Roberto Furlan, Giancarlo Comi, Letizia Leocani

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    • P0771 - Susac syndrome – a differential diagnosis of demyelinating process (View Presentation)

      Keyword: Neuro-Ophthalmology

      Anna Jamroz-Wiśniewska, Klaudia Sapko, Anna Woźniak, Michał Marciniec, Marcin Kulczyński, Robert Rejdak, Konrad Rejdak

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    • P0772 - The optic nerve as a 5th location for dissemination in space for multiple sclerosis criteria: a role for optical coherence tomography (View Presentation)

      Keyword: Neuro-Ophthalmology

      Axel Petzold, Sharon Chua, Anthony Khawaja, Pearse Keane, Sir Peng Khaw, Charles Reisman, Baljean Dhillon, Nicholas Strouthidis, Paul Foster, Praveen Patel

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    • P0773 - Variation of RNFL thickness in MS patients and DMTs: a longitudinal study. (View Presentation)

      Keyword: Neuro-Ophthalmology

      Jessica Frau, Giancarlo Coghe, Benedetta Pintus, Marzia Fronza, Lorena Lorefice, Giuseppe Fenu, Eleonora Cocco

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    • P0774 - Bryostatin-1 modulates CNS innate immunity and augments remyelination (View Presentation)

      Keyword: Neuroprotection, Regeneration and/or Remyelination

      Efrat Abramson, Payam Gharibani, Jingwen Hu, Matthew Smith, Soonmyung Hwang, Peter Calabresi, Jeffrey Huang, Paul Kim, Michael Kornberg

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    • P0775 - Development of a screening platform that uses genome engineered hPSC-Derived OPCs for the discovery of remyelination promoting compounds (View Presentation)

      Keyword: Neuroprotection, Regeneration and/or Remyelination

      Xitiz Chamling, Cynthia Berlinicke, Felipe Takaesu, Yukan Duan, Xiaoli Chang, Peter Calabresi, Donald Zack

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    • P0776 - Dual threats of CSPGs in multiple sclerosis through inhibiting oligodendrocyte repair and polarizing Th17 cells (View Presentation)

      Keyword: Neuroprotection, Regeneration and/or Remyelination

      samira Ghorbani, Ping Zhang, Deepak Kaushik, Benjamin Buehner, Cenxiao Li, Chang Ling, Voon Yong

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    • P0777 - High-content drug screening in human iPSC-derived oligodendrocytes identifies novel pathways to promote oligodendrocyte differentiation (View Presentation)

      Keyword: Neuroprotection, Regeneration and/or Remyelination

      Leolie Telford-Cooke, Dario Magnani, Rebecca Holloway, James Longden, John Dawson, Karen Burr, David Story, Veronique Miron, Siddharthan Chandran, Neil Carragher

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    • P0778 - IL-10 promotes myelin repair in an ex vivo model of remyelination and microRNA signatures of ex vivo remyelination (View Presentation)

      Keyword: Neuroprotection, Regeneration and/or Remyelination

      Conor Duffy, Claire McCoy, María Muñoz San Martín

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    • P0779 - Lipid handling by macrophages and microglia is impaired in the aging CNS after demyelination (View Presentation)

      Keyword: Neuroprotection, Regeneration and/or Remyelination

      Manoj Mishra, Debora Cisterna, Nathan Michaels, Voon Yong

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    • P0781 - Myeloid-Derived Suppressor Cells associated to a mild disease course are good bioindicators of a higher remyelinating capability in Multiple Sclerosis (View Presentation)

      Keyword: Neuroprotection, Regeneration and/or Remyelination

      Celia Camacho-Toledano, Rafael Lebrón-Galán, Isable Machín-Díaz, Jennifer García-Arocha, Maria Cristina Ortega, Diego Clemente

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    • P0782 - Myeloid-derived suppressor cells in progressive multiple sclerosis: important factors for clinical course severity (View Presentation)

      Keyword: Neuroprotection, Regeneration and/or Remyelination

      Maria Cristina Ortega, Jennifer García-Arocha, Victor Quintanero-Casero, Rafael Lebrón-Galán, Isable Machín-Díaz, Celia Camacho-Toledano, Diego Clemente

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    • P0783 - Neuromodulation through anodal tDCS promotes recovery of demyelination-induced motor impairments in cuprizone demyelination/remyelination mouse model (View Presentation)

      Keyword: Neuroprotection, Regeneration and/or Remyelination

      Raffaele D'Isa, Silvia Marenna, Valerio Castoldi, Giancarlo Comi, Letizia Leocani

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    • P0784 - RENEWED:Long-term mfVEP latency outcomes in Participants Previously Enrolled in the Opicinumab Phase 2 Study RENEW. (View Presentation)

      Keyword: Neuroprotection, Regeneration and/or Remyelination

      Alexander Klistorner, Maria Naylor, Bing Zhu

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    • P0785 - Super-low combination therapy as a pathway to treatment against disease progression. (View Presentation)

      Keyword: Neuroprotection, Regeneration and/or Remyelination

      Robert Fern, Verity Mitchener, Carlos Matute

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    • P0786 - Anti-NMDA receptor encephalitis presenting as focal temporal lobe seizures with mixed transcortical aphasia. (View Presentation)

      Keyword: Neuropsychology and Cognition

      Aditi Varma-Doyle, Rachel Evans, Mary Lewis, Charles Clines, Ebony McKinnies, Edward Mader, Lionel Branch

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    • P0787 - Associations between cognitive and clinical disability across MS subtypes: the role of the underlying brain damage (View Presentation)

      Keyword: Neuropsychology and Cognition

      Larissa Gois, Alfredo Damasceno, Benito Damasceno, Luciana Pimentel-Silva

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    • P0788 - Atrophy of the posterior cerebellar lobules is related to episodic memory difficulties in patients with multiple sclerosis: a 3T MRI study. (View Presentation)

      Keyword: Neuropsychology and Cognition

      Elisabetta Mancuso, Giacomo Boffa, caterina Lapucci, matteo Moro, eleonora Colombo, francesco Tazza, Maria Cellerino, nicolò Bruschi, elvira Sbragia, riccardo Meli, matilde Inglese

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    • P0789 - Benchmarks of meaningful improvement on neurocognitive tests (View Presentation)

      Keyword: Neuropsychology and Cognition

      Curtis Wojcik, Michael Dwyer, Michael Jaworski, Margaret Youngs, Mahmut Unverdi, Bianca Weinstock-Guttman, Ralph Benedict

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    • P0790 - Brain Reserve and Cognitive Reserve on Social Cognition in Multiple Sclerosis: What roles? (View Presentation)

      Keyword: Neuropsychology and Cognition

      Rita Machado, Cláudia Lima, Otília C. D´almeida, Ana Afonso, Carmo Macário, Miguel Castelo-Branco, Lívia Sousa, Isabel Santana, Sónia Batista

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    • P0791 - Cerebellar dysfunction correlates with cognitive impairment in relapsing-remitting multiple sclerosis: A cross-sectional study (View Presentation)

      Keyword: Neuropsychology and Cognition

      Manuel Salavisa, Ana Filipa Graça, Filipa Serrazina, Joana Graça, Ana Sofia Correia

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    • P0792 - Cerebrospinal fluid amyloid-β as potential biomarker for cognitive functioning in multiple sclerosis. (View Presentation)

      Keyword: Neuropsychology and Cognition

      Maureen Van Dam, Eline Willemse, I. Nauta, Marijn Huiskamp, Martin Klein, Bastiaan Moraal, Jeroen Geurts, Bernard Uitdehaag, Charlotte Teunissen, Brigit De Jong, Hanneke Hulst

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    • P0793 - Clinical course impacts on the association between general cognition and mentalizing deficits in MS (View Presentation)

      Keyword: Neuropsychology and Cognition

      Matteo Pardini, eleonora Colombo, Riccardo Meli, caterina Lapucci, Nicolò Bruschi, Giacomo Boffa, Maria Cellerino, elvira Sbragia, Antonio Uccelli, Matilde Inglese

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    • P0794 - Clinical utility of the Processing Speed Test in patients with multiple sclerosis (View Presentation)

      Keyword: Neuropsychology and Cognition

      Yusei Miyazaki, Masaaki Niino, Eri Takahashi, Ryoji Naganuma, Itaru Amino, Fumihito Nakano, Sachiko Akimoto, Naoya Minami, Seiji Kikuchi

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    • P0795 - Cognitive and psychological predictors of self-management behaviors in persons with multiple sclerosis (View Presentation)

      Keyword: Neuropsychology and Cognition

      Elizabeth Gromisch, Lindsay Neto, Aaron Turner

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    • P0796 - Cognitive differences in aging patients with multiple sclerosis compared to healthy controls (View Presentation)

      Keyword: Neuropsychology and Cognition

      Yolanda Higueras, María L Martínez-Ginés, Virginia Meca-Lallana, Ariana Meldaña-Rivera, Jose Manuel García-Domínguez, Juan Pablo Cuello, Alberto Lozano-Ros, Haydee Goicochea Briceño, R.G González-Cuenca, Clara Aguirre, Javier González-Marqués, Jose Vivancos, Fabiola García-Vaz

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    • P0797 - Cognitive Event-Related Potentials in Multiple Sclerosis. (View Presentation)

      Keyword: Neuropsychology and Cognition

      Artemios Artemiadis, Christos Bakirtzis, George Nikolaou, Georgios Hadjigeorgiou, Maria Anagnostouli

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    • P0798 - Cognitive function in radiologically isolated syndrome (View Presentation)

      Keyword: Neuropsychology and Cognition

      HELENA Martinez Herves, MARTA Aguado Valcarcel, Inés González-Suárez, Elena Alvarez, CESAR MANUEL Sanchez Franco, LAURA Bello Otero, CLARA HELENA Lopez Caneda, IAGO Couso PazÓ, SARA Sequeiros



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    • P0799 - Cognitive impairment in pediatric multiple sclerosis: the age of onset as a probable predictive variable. (View Presentation)

      Keyword: Neuropsychology and Cognition

      Mariia Bogdanova, Yuri Mikadze, Tatyana Batysheva, Raisa Bembeeva, Elvira Volkova

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    • P0800 - Cognitive-Motor Interference and Cortical Activation during Walking and Turning in Individuals with Multiple Sclerosis (View Presentation)

      Keyword: Neuropsychology and Cognition

      Michael Vannostrand, Brittany Belanger, Susan Kasser, Michael Cannizzaro

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    • P0801 - Default Mode Network functioning and Multiple Sclerosis: the importance of phenotypes and cognition (View Presentation)

      Keyword: Neuropsychology and Cognition

      Jose Manuel García-Domínguez, Yolanda Higueras, Juan Alvarez Linera, Ariana Meldaña-Rivera, Juan Pablo Cuello, Gracian Garcia Marti, Alberto Lozano-Ros, Haydee Goicochea Briceño, María L Martínez-Ginés

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    • P0802 - Differences in Regional Cortical Thickness and Subcortical Volumes Among Cognitively Impaired and Unimpaired Multiple Sclerosis Patients (View Presentation)

      Keyword: Neuropsychology and Cognition

      Charles Tyshkov, Melanie Marcille, Abhishek Jaywant, Ulrike W Kaunzner, Jai Perumal, Nancy Nealon, Tim Vartanian, Nicole Zinger, Lily Zexter, Sandra Hurtado Rua, Susan Gauthier

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    • P0803 - Discriminating Spatialised Speech in Complex Environments in Multiple Sclerosis (View Presentation)

      Keyword: Neuropsychology and Cognition

      Pippa Iva, Russell Martin, Joanne Fielding, Meaghan Clough, Owen White, Gustavo Noffs, Branislava Godic, Anneke Van Der Walt, Ramesh Rajan

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    • P0804 - Dual task during walking in patients with Multiple Sclerosis: cognitive or motor interference?   (View Presentation)

      Keyword: Neuropsychology and Cognition

      Maria Barbara Eizaguirre, Natalia Ciufia, Aldana Marinangeli, Maria Román, Camila Diven Arguello, Leila Cohen, Berenice Silva, Ricardo Alonso, Sandra Vanotti, orlando Garcea

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    • P0805 - Dynamics of cognitive decline along the disease course in multiple sclerosis (View Presentation)

      Keyword: Neuropsychology and Cognition

      Elisabet Lopez-Soley, Eli Solana, Magi Andorra, Eloy Martinez-Heras, Carmen Montejo, Irene Pulido-Valdeolivas, Maria Sepulveda, Yolanda Blanco, Salut Alba-Arbalat, Elena Martinez-Lapiscina, Pablo Villoslada, Albert Saiz, Sara Llufriu

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    • P0806 - Effect of siponimod on cognitive processing speed in SPMS patients with active and non-active disease (View Presentation)

      Keyword: Neuropsychology and Cognition

      Shannon Ritter, Iris-Katharina Penner, Gavin Giovannoni, Bruce A.C. Cree, Robert Fox, Amit Bar-Or, Ralf Gold, Patrick Vermersch, Thomas Hach, Karlsson Goeril, Shannon Ritter, Nicolas Rouyrre, Daniela Piani-Meier, Ralph Benedict

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    • P0807 - Evaluating cognitive functioning in Multiple Sclerosis, compared to other neurological disorders, using an online cognitive battery (View Presentation)

      Keyword: Neuropsychology and Cognition

      Carola Di Bella, William Trender, Peter Hellyer, Sarah Knowles, Joe Hill, Stefano Sandrone, Richard Nicholas, Adam Hampshire

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    • P0808 - Evaluation of psychiatric characteristics in children of parents with multiple sclerosis   (View Presentation)

      Keyword: Neuropsychology and Cognition

      Sibel Guler



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    • P0809 - Extended Interval Dosing Natalizumab and cognitive function in Relapsing-Remitting Multiple Sclerosis patients: A retrospective audit (View Presentation)

      Keyword: Neuropsychology and Cognition

      Eileen Mc Manus, Karen Clark, Jamie Macniven, Jan Schepel

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    • P0810 - Great Expectations in Multiple Sclerosis (GEMS):  Does effortful reading improve cognitive performance in multiple sclerosis? (View Presentation)

      Keyword: Neuropsychology and Cognition

      Kris French, Erika Duffy

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    • P0811 - Higher hippocampal functional connectivity in preclinical and initial stages of multiple sclerosis (View Presentation)

      Keyword: Neuropsychology and Cognition

      Judit Salavedra-Pont, Oren Contreras-Rodriguez, Carles Biarnés-Duran, Ester Quintana, Clàudia Coll-Martinez, Belen Moreno, Maria Buxó, René Robles Cedeño, Lluís Ramió-Torrentà, Jordi Gich

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    • P0812 - Hippocampal resting-state functional connectivity in Multiple Sclerosis subtypes (View Presentation)

      Keyword: Neuropsychology and Cognition

      Judit Salavedra-Pont, Oren Contreras-Rodriguez, Carles Biarnés-Duran, Ester Quintana, Clàudia Coll-Martinez, Belen Moreno, René Robles Cedeño, Lluís Ramió-Torrentà, Jordi Gich

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    • P0813 - Impact of multiple sclerosis on cognitive aging: a multicenter study (View Presentation)

      Keyword: Neuropsychology and Cognition

      Damiano Mistri, Alessandro Meani, Gioacchino Tedeschi, Patrizia Pantano, Paola Zaratin, Nicola De Stefano, Paolo Preziosa, Maria A. Rocca, Massimo Filippi

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    • P0814 - Is Trait anxiety  a predictor of dysexecutive complaints in multiple sclerosis? (View Presentation)

      Keyword: Neuropsychology and Cognition

      Fabiola Garcia-Vaz, Virginia Meca-Lallana, Clara Aguirre, Beatriz Del Río, Maria Mayoral, Paula Martin-Rojas, Javier Gonzalez Marques, Jose Vivancos

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    • P0816 - Neurocognition, anxiety, depression and its relation with quality of life in patients with relapsing remitting multiple sclerosis (View Presentation)

      Keyword: Neuropsychology and Cognition

      vinayaka Yadav, Shantala Hegde, Netravathi M

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    • P0817 - Neurocognitive performance in multiple sclerosis patients correlates with hippocampal metabolite abnormalities - 1H MRS study (View Presentation)

      Keyword: Neuropsychology and Cognition

      Ema Kantorová, Petra Hnilicová, Egon Kurča, Wolfgang Bogner

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    • P0818 - Pain influence on information processing speed alteration in patients with Multiple Sclerosis (View Presentation)

      Keyword: Neuropsychology and Cognition

      Pauline Paris, Delphine Cregut, Veronique Germain, Marion Gibelin, Bruno Pereira, Frederic Taithe, Dominique Aufauvre, Pierre Clavelou, Xavier Moisset



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    • P0819 - Perceived Social Support in Multiple Sclerosis: Impact on patient’s quality of life. (View Presentation)

      Keyword: Neuropsychology and Cognition

      Maria Barbara Eizaguirre, Cecilia Yastremiz, Angeles Merino, Daniela Rodrigo, Daiana Taboada, Cecilia Pita, Berenice Silva, Ricardo Alonso, Sandra Vanotti, orlando Garcea

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    • P0820 - Phase II trial of cognitive rehabilitation in patients with multiple sclerosis: preliminary results (View Presentation)

      Keyword: Neuropsychology and Cognition

      Elisabet Lopez-Soley, Eli Solana, Eloy Martinez-Heras, Elvira Munteis, Cristina Ramo, Silvia Presas-Rodríguez, Mariona Hervas, Lucía Romero-Pinel, Raul Pelayo, Rocio Sanchez-Carrion, Montserrat Bernabeu, Carmen Montejo, Maria Sepulveda, Nuria Sola-Valls, Yolanda Blanco, Irene Pulido-Valdeolivas, Magi Andorra, Salut Alba-Arbalat, Albert Saiz, Sara Llufriu

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    • P0821 - Prevalence data of Cognitive Impairment in patients with Multiple Sclerosis of good clinical evolution in a cohort of patients from the city of Lleida (View Presentation)

      Keyword: Neuropsychology and Cognition

      Anna Gil, Marc Canudes, Lara Nogueras, Cristina Gonzalez-Mingot, José Vicente Hervás-García, Silvia Peralta, Mª José Solana, LUIS Brieva

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    • P0822 - Processing speed improves prediction of physical impairment in patients with multiple sclerosis (View Presentation)

      Keyword: Neuropsychology and Cognition

      Stefanie Hechenberger, Daniela Pinter, Birgit Helmlinger, Alexander Pichler, Michael Khalil, Christian Enzinger

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    • P0823 - Resting state functional connectivity correlates of executive function in patients with multiple sclerosis (View Presentation)

      Keyword: Neuropsychology and Cognition

      Olga Marchesi, Paola Valsasina, Lorenzo Conti, Damiano Mistri, Paolo Preziosa, Massimo Filippi, Maria A. Rocca

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    • P0824 - Serum neurofilaments and Cognition in Secondary Progressive Multiple Sclerosis (View Presentation)

      Keyword: Neuropsychology and Cognition

      Thomas Williams, Carmen Tur, Anisha Doshi, Henny Wellington, Dennis Chan, Sophie Banks, Amanda Heslegrave, Henrik Zetterberg, Jeremy Chataway

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    • P0825 - Social cognition impairment - a clinical biomarker of Multiple Sclerosis? (View Presentation)

      Keyword: Neuropsychology and Cognition

      Cláudia Lima, Rita Machado, Ana Afonso, Carmo Macário, Lívia Sousa, Isabel Santana, Sónia Batista

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    • P0826 - Social emotions in patients with multiple sclerosis (View Presentation)

      Keyword: Neuropsychology and Cognition

      Fátima Pagani Cassará, Sofia Maid, Julieta Gutnisky, Sol Fittipaldi, Sandra Báez, Agustín Ibáñez, Adolfo M. García, Vladimiro Sinay

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    • P0827 - Speed of Lexical Access Contributes to Verbal Memory Retrieval in MS.  (View Presentation)

      Keyword: Neuropsychology and Cognition

      Emily Dvorak, Rachel Brandstadter, James Sumowski

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    • P0828 - Synaptic plasticity is reduced in patients with RRMS compared to healthy controls and associated with neuropsychological outcomes (View Presentation)

      Keyword: Neuropsychology and Cognition

      Carolin Balloff, Stefan Groiss, Meng Ma, Lina Scala, Iason Georgiades, Nina Troullinakis, Jonas Graf, Orhan Aktas, Hans Peter Hartung, Alfons Schnitzler, Iris-Katharina Penner, Philipp Albrecht

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    • P0829 - The adapted Symbol Digit Modalities Test: a proof of concept study (View Presentation)

      Keyword: Neuropsychology and Cognition

      Silvana Costa, Lauren Strober, Tara Alvarez, Kristen Costanza, Alec Degraaf, Henry Talasan, John Deluca, Nancy Chiaravalloti

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    • P0830 - Unraveling the substrates of cognitive impairment in multiple sclerosis: the contribution of a multiparametric structural and functional MRI approach (View Presentation)

      Keyword: Neuropsychology and Cognition

      Lorenzo Conti, Paolo Preziosa, Alessandro Meani, Carmen Vizzino, Gianna Riccitelli, Elisabetta Pagani, Paola Valsasina, Olga Marchesi, Massimo Filippi, Maria A. Rocca

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    • P0831 - Validation of longitudinal reaction time trajectories in multiple sclerosis using the MSReactor computerized battery and latent class analysis. (View Presentation)

      Keyword: Neuropsychology and Cognition

      Daniel Merlo, Jim Stankovich, Claire Bae, Tomas Kalincik, Melissa Gresle, Jeannette Lechner-Scott, Trevor Kilpatrick, Michael Barnett, Bruce Taylor, David Darby, Helmut Butzkueven, Anneke Van Der Walt

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    • P0832 - XO as a new screening test of cognitive impairment in multiple sclerosis (View Presentation)

      Keyword: Neuropsychology and Cognition

      Pauline Paris, Delphine Cregut, Veronique Germain, Marie Izaute, Marion Gibelin, Bruno Pereira, Frederic Taithe, Dominique Aufauvre, Xavier Moisset, Pierre Clavelou



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    • P0833 - “Stable” vs. “Silent Progressive Multiple Sclerosis”: A Real World Retrospective Clinical Imaging Brazilian Study (View Presentation)

      Keyword: Observational Studies

      Fernando Figueira, Gustavo Figueira, Paula Soares, Raquel Silveira

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    • P0834 - A comparative study of teriflunomide and dimethyl fumarate within the Swedish MS Registry (View Presentation)

      Keyword: Observational Studies

      Tim Spelman, Jan Hillert, Jon Tsai, Mona Nouhi, Anna Glaser

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    • P0835 - A First Look at the Characteristics of Patients with Multiple Sclerosis Initiating Siponimod Therapy in the United States (View Presentation)

      Keyword: Observational Studies

      Roshani Shah, Magdaliz Gorritz, Rolin Wade, Jasjit Multani, Hsiu-Ching Chang, Karishma Shelley, Gina Cox, Kristen Johnson

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    • P0836 - Aggressive multiple sclerosis in Argentina: data from the nationwide registry RelevarEM (View Presentation)

      Keyword: Observational Studies

      Matías Kohler, Eduardo Kohler, Carlos Vrech, Agustin Pappolla, Jimena Miguez, Liliana Patrucco, Jorge Correale, Mariano Marrodan, María Gaitán, Marcela Fiol, Laura Negrotto, María Ysrraelit, Edgardo Cristiano, Adriana Carra, Anibal Chertcoff, Judith Steinberg, Alejandra Martinez, Celeste Curbelo, Leila Cohen, Ricardo Alonso, orlando Garcea, Cecilia Pita, Berenice Silva, Geraldine Luetic, Norma Deri, Maria Eugenia Balbuena, Veronica Tkachuk, Edgar Carnero Contentti, Pablo Lopez, Juan Pettinicchi, alejandro Caride, Marcos Burgos, Felisa Leguizamon, Eduardo Knorre, Raúl Piedrabuena, Andres Barboza, Susana Liwacki, Pedro Nofal, Gabriel Volman, Amelia Alves Pinheiro, Javier Hryb, Darío Tavolini, Patricio Blaya, Luciano Recchia, Carolina Mainella, Emanuel Silva, Jorge Blanche, Santiago Tizio, María Saladino, Fernando Caceres, Nora Fernandez Liguori, Luciana Lazaro, Gisela Zanga, Marcela Parada Marcilla, Maria Eugenia Fracaro, Fátima Pagani Cassará, Guido Vazquez, Vladimiro Sinay, Gustavo Sgrilli, Pablo Divi, Miguel Jacobo, Edgardo Reich, Lorena Cabrera, Maria Menichini, Mariano Coppola, Ivan Martos, Juan Viglione, Gustavo Jose, Santiago Bestoso, Ruben Manzi, Diego Giunta, Maria Doldan, Marina Alonso Serena, Juan Rojas

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    • P0837 - Assessing the real-world effectiveness of ocrelizumab in patients with multiple sclerosis – CONFIDENCE one-year interim analysis (View Presentation)

      Keyword: Observational Studies

      Mathias Buttmann, Sven Meuth, Martin Weber, Petra Dirks, Julius Eggebrecht, Stefanie Hieke-Schulz, Jost Leemhuis, Tjalf Ziemssen

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    • P0838 - Autonomic dysfunction in patients with relapsing-remitting multiple sclerosis treated with different oral disease modifying therapies – a pilot study (View Presentation)

      Keyword: Observational Studies

      Marcin Wnuk, Marcin Tutaj, Leszek Drabik, Monika Marona, Matylda Gliniak, Alicja Kepinska-Wnuk, Karolina Porebska, Klaudia Nowak, Katarzyna Sawczynska, Malgorzata Wlodarczyk, Agnieszka Slowik

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    • P0839 - Baseline Characteristics of AMASIA: First Real World Data of Siponimod Treated Patients with Secondary Progressive Multiple Sclerosis (View Presentation)

      Keyword: Observational Studies

      Martin Weber, Luisa Klotz, Herbert Schreiber, Benedict Rauser, Tjalf Ziemssen

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    • P0840 - Benign Multiple Sclerosis: Is the EDSS scale enough to define it?  (View Presentation)

      Keyword: Observational Studies

      Elisabet Matas, Laura Bau, Lucía Romero-Pinel, Isabel León, Antonio Martínez-Yélamos, Sergio Martínez-Yélamos

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    • P0841 - Brain volume loss during the first year and physical and cognitive impairment over 3 years in naïve multiple sclerosis patients under fingolimod (View Presentation)

      Keyword: Observational Studies

      Juan Rojas, Francisco Sanchez, Liliana Patrucco, Agustin Papolla, Jimena Miguez, Edgardo Cristiano

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    • P0842 - Changes in Copaxone usage of MS patients within British Columbia upon recommended switch to generic. (View Presentation)

      Keyword: Observational Studies

      Kanha Shete, Maria-Elizabeth Baeva, Jill Nelson, Anna Kazimirchik, Galina Vorobeychik

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    • P0843 - Characteristics and clinical outcomes of older patients with MS treated with peginterferon beta-1a or intramuscular interferon beta-1a in MS PATHS (View Presentation)

      Keyword: Observational Studies

      Christina Eavis, Le Hanh Hua, Shirley Liao, Carrie Hersh, Kathryn Fitzgerald, Arman Altincatal, Maria Naylor

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    • P0844 - Characteristics and treatment patterns of older MS patients treated with peginterferon beta-1a or intramuscular interferon beta-1a in the real world (View Presentation)

      Keyword: Observational Studies

      Christina Eavis, Megan Vignos, Arman Altincatal, Jason Mendoza, Robin Avila, Charles Makin

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    • P0845 - Characteristics of patients initiating ocrelizumab vs other disease-modifying therapies in a US national multiple sclerosis registry (View Presentation)

      Keyword: Observational Studies

      Michelle Gheen, Daniel Kantor, Natalie Engmann, Wendi Malley, Robert McLean, Angel Cronin, Blessing Dube, Aaron Miller

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    • P0846 - Characteristics of relapsing multiple sclerosis patients treated with cladribine tablets in five European countries: multi-year chart review (View Presentation)

      Keyword: Observational Studies

      James Plested, Feng Zeng, Gerard Harty, Schiffon Wong, Ekaterina Maslova, René Schade, Bill Row

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    • P0847 - Characterization of relapsing multiple sclerosis patients treated with cladribine tablets in Germany since marketing authorization (View Presentation)

      Keyword: Observational Studies

      James Plested, Feng Zeng, Gerard Harty, Schiffon Wong, Susanne Uebler, Ekaterina Maslova, René Schade, Bill Row, David Ellenberger, Alexander Stahmann

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    • P0848 - Characterization of Retinal Nerve Fiber Layer Thickness in a Cohort with Glutamic Acid Decarboxylase and Glycine Receptor Autoimmunity (View Presentation)

      Keyword: Observational Studies

      Robert Kadish, Ka-Ho Wong, Jonathan Galli, John Greenlee, Julia Klein, Mateo Paz Soldán, Stacey Clardy, Anette Loughran-Fjeldstad, John Rose

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    • P0849 - CLADQoL (CLADribine Tablets – evaluation of Quality of Life) study: evaluating Qol 12 months after treatment initiation with cladribine tablets (View Presentation)

      Keyword: Observational Studies

      Iris-Katharina Penner, Refik Pul, Boris-Alexander Kallmann, Alaleh Raji, Joachim Richter, Torsten Wagner, Beate Mueller, Tanja Buescher, Anita Posevitz-Fejfar

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    • P0850 - Cladribine personalised dosing to treat multiple sclerosis: observations in 208 patients (View Presentation)

      Keyword: Observational Studies

      Kimberley Allen-Philbey, Stefania De Trane, Andrea Stennett, Ozlem Yildiz, Ashok Adams, Ben Turner, Monica Marta, Sharmilee Gnanapavan, Lucia Bianchi, Joela Mathews, Dan Altmann, Gavin Giovannoni, David Baker, Klaus Schmierer

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    • P0851 - Clinical & demographic determinants of self-reported diet program adherence in people living with multiple sclerosis (View Presentation)

      Keyword: Observational Studies

      Mohamed Jakaria, Nupur Nag, Sandra Neate, George Jelinek, Tracey Weiland, Steve Simpson-Yap

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    • P0852 - Clinical activity after fingolimod treatment in naïve RRMS patients compared to patients previously treated with other drugs (View Presentation)

      Keyword: Observational Studies

      Miryam Cannizzaro, Laura Ferrè, Francesca Sangalli, Bruno Colombo, Lucia Moiola, Vittorio Martinelli, Massimo Filippi, Federica Esposito

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    • P0853 - Clinical and videonystagmographical evaluation of vestibular manifestations in multiple sclerosis. (View Presentation)

      Keyword: Observational Studies

      Salma El Alaoui El Rhoul, Mohammed Ridal, Naouar Ouattassi, SIHAM Bouchal, Mohamed El Amine El Alami, Mohammed Belahssen

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    • P0854 - Clinical characteristics of middle-aged and older patients with MS treated with interferon beta-1b in the BEACON study (View Presentation)

      Keyword: Observational Studies

      Francesco Patti, Javier Nicolas Penaherrera, Eva-Maria Wicklein

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    • P0855 - Clinical Course and Therapeutic Management of SPMS in France: a retrospective real world multicentric observational study (ODYSSEP Study) (View Presentation)

      Keyword: Observational Studies

      Emmanuelle Leray, Alexandre Bastien, Karin Rerat, Aurélia Cognée-Chauvin, Eric Raponi, Sandra Vukusic

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    • P0856 - Collecting real world MRI in MS: preliminary results from FlywheelMS (View Presentation)

      Keyword: Observational Studies

      Michelle Gheen, Anthony Traboulsee, Wim Van Hecke, Dirk Smeets, Gillian Hanson, Kiernan Mace, Alex Rovira, Roland Henry, David Li, Ryan Gan, Laura Julian, Katherine Belediuk, Laura Gaetano

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    • P0857 - Comorbidity and Economic Burdens of Fatigue Among Patients with Relapsing-Remitting Multiple Sclerosis in the United States (View Presentation)

      Keyword: Observational Studies

      Hoa Le, Jennifer Ken-Opurum, Martine Maculaitis, John Sheehan

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    • P0858 - Comparative effectiveness of dimethyl fumarate versus other disease-modifying therapies in Multiple Sclerosis: a large population-based cohort study (View Presentation)

      Keyword: Observational Studies

      Pauline Bosco-Lévy, Patrick Blin, Séverine Lignot-Maleyran, Régis Lassalle, Abdelilah Abouelfath, Pauline Diez-Andreu, Marc Debouverie, Bruno Brochet, francis Guillemin, Nicholas Moore, Droz-Perroteau Cécile

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  • PO04 - On-Demand ePosters P0859-P1144

    • Type: Poster
    • Presentations: 278
    Presented on: 9/11/2020, 08:00
    View Posters

    • P0859 - Comparative effectiveness of natalizumab, fingolimod, and first-line therapies for rapidly evolving severe relapsing-remitting multiple sclerosis (View Presentation)

      Keyword: Observational Studies

      Christina Eavis, Tim Spelman, Carlos Acosta, Robert Hyde, Nolan Campbell, Eva Havrdova, Dana Horakova, Maria Trojano, Giovanna De Luca, Alessandra Lugaresi, Guillermo Izquierdo, Pierre Grammond, Pierre Duquette, Raed Alroughani, Eugenio Pucci, Franco Granella, Jeannette Lechner-Scott, Patrizia Sola, Diana Ferraro, Francois Grand-Maison, Murat Terzi, Csilla Rozsa, Cavit Boz, Raymond Hupperts, Anneke Van Der Walt, Vincent Van Pesch, Celia Oreja-Guevara, Vilija Jokubaitis, Tomas Kalincik, Helmut Butzkueven

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    • P0862 - Disability accrual in primary-progressive & secondary-progressive multiple sclerosis (View Presentation)

      Keyword: Observational Studies

      Sam Harding-Forrester, Izanne Roos, Sifat Sharmin, Ibrahima Diouf, Charles Malpas, Ai-Lan Nguyen, Nahid Moradi, Dana Horáková, Eva Kubala Havrdová, Francesco Patti, Guillermo Izquierdo, Sara Eichau, Alexandre Prat, Marc Girard, Pierre Duquette, Marco Onofrj, Alessandra Lugaresi, Francois Grand'Maison, Bianca Weinstock-Guttman, Maria Pia Amato, Pierre Grammond, Oliver Gerlach, Serkan Ozakbas, Patrizia Sola, Diana Ferraro, Helmut Butzkueven, Jeannette Lechner-Scott, Cavit Boz, Raed Alroughani, Vincent Van Pesch, Elisabetta Cartechini, Murat Terzi, Davide Maimone, Cristina Ramo-Tello, Daniele Spitaleri, Ludwig Kappos, Bassem Yamout, Maria Sá, Mark Slee, Yolanda Blanco, Roberto Bergamaschi, Ernest Butler, Gerardo Iuliano, Franco Granella, Youssef Sidhom, Riadh Gouider, Radek Ampapa, Bart Van Wijmeersch, R Karabudak, Julie Prevost, José Luis Sánchez-Menoyo, Freek Verheul, Pamela McCombe, Tamara Castillo-Triviño, Richard Macdonell, Ayse Altintas, Guy Laureys, Liesbeth Van Hijfte, Anneke Van Der Walt, Steve Vucic, Recai Turkoglu, Michael Barnett, Edgardo Cristiano, Magd Zakaria, Vahid Shaygannejad, Suzanne Hodgkinson, Aysun Soysal, Tomas Kalincik

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    • P0863 - Discontinuation and dose reduction of rituximab in patients with relapsing remitting multiple sclerosis (View Presentation)

      Keyword: Observational Studies

      Malin Boremalm, Peter Sundström, Jonatan Salzer

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    • P0864 - Disease Modifying Therapies in People Newly Diagnosed with Multiple Sclerosis (View Presentation)

      Keyword: Observational Studies

      Gloria Von Geldern, Annette Wundes, Dev Mehta, Sargon Bet-Shlimon, Kevin Alschuler

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    • P0865 - Disease modifying therapy utilization is influenced by system-level factors: Real-world evidence from the MS-CQI improvement collaborative study. (View Presentation)

      Keyword: Observational Studies

      BRANT Oliver, FALGUNI Mehta, Karen Walsh, Laetitia N'Dri, Dexter Waters

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    • P0866 - Disease-Modifying Therapy of Multiple Sclerosis with Ocrelizumab: a two years experience of MS Clinic in the Eastern Region of Abu Dhabi Emirate, UAE (View Presentation)

      Keyword: Observational Studies

      Ali Hassan, Heba Elhasin, Noha Soliman, Miklos Szolics

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    • P0867 - Dynamics of brain volume loss during 3 years in multiple sclerosis patients with cognitive impairment: prospective cohort study (View Presentation)

      Keyword: Observational Studies

      Juan Rojas, Francisco Sanchez, Liliana Patrucco, Agustin Papolla, Edgardo Cristiano

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    • P0868 - Early experience with ocrelizumab in Denmark. A population-based registry study (View Presentation)

      Keyword: Observational Studies

      Melinda Magyari, Luigi Pontieri, Morten Blinkenberg, Viktoria Papp, Peter Rasmussen, Jakob Schäfer, Jonas Berg, Matthias Kant, Henrik Mathiesen, Michael Jensen, Georgi Sirakov, Annett Petersen, Stephan Bramow, Finn Sellebjerg

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    • P0869 - effectiveness and safety of rituximab in routine clinical practice: a retrospective analysis of mexican patients with progressive multiple sclerosis (View Presentation)

      Keyword: Observational Studies

      David Bernal Varela, LUIS Molina Carrion

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    • P0870 - Effectiveness of Disease-Modifying Therapies in Relapsing Multiple Sclerosis in South China. (View Presentation)

      Keyword: Observational Studies

      Vanessa Tao, Lin Zhao, Cheryl Au, Angel Ng, Vincent Mok, Alexander Lau

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    • P0871 - Efficacy and safety of dimethyl fumarate in progressive multiple sclerosis (View Presentation)

      Keyword: Observational Studies

      Vanessa Fernanda Moreira Ferreira, Yanqing Liu, Brian Healy, James Stankiewicz

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    • P0872 - Efficacy and Safety of Intravenous and Subcutaneous Cladribine in Relapsing and Progressive Multiple Sclerosis: a 24-year retrospective (View Presentation)

      Keyword: Observational Studies

      Michael Ko, George Katsamakis, Roumen Balabanov, Dusan Stefoski

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    • P0873 - Experience with teriflunomide in a specialized multiple sclerosis unit (View Presentation)

      Keyword: Observational Studies

      Lluís Ramió-Torrentà, Gary Alvarez Bravo, Héctor Perkal, Miguel Merchán, Marina González, René Robles Cedeño

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    • P0874 - Fingolimod therapy in real world relapsing MS patients: Cognition, quantitative MRI and deep gray matter quantitative susceptibility mapping (View Presentation)

      Keyword: Observational Studies

      Heidi Beadnall, Bianca Weinstock-Guttman, Chenyu Wang, Jesper Hagemeier, Niels Bergsland, Dejan Jakimovski, Murali Ramanathan, Linda Ly, Michael Dwyer, Ferdinand Schweser, Todd Hardy, Ralph Benedict, Michael Barnett, Robert Zivadinov

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    • P0875 - FlywheelMS: The prevalence of multiple sclerosis subtypes in digitized health records (View Presentation)

      Keyword: Observational Studies

      Michelle Gheen, Ryan Gan, Shemra Rizzo, Jenny Chia, Gillian Hanson, Kiernan Mace, Laura Julian, Laura Gaetano, Katherine Belendiuk

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    • P0876 - High and low efficacy therapy in secondary progressive multiple sclerosis after accounting for therapeutic lag. (View Presentation)

      Keyword: Observational Studies

      Izanne Roos, Emmanuelle Leray, Romain Casey, Dana Horakova, Eva Kubala Havrdová, Guillermo Izquierdo, Sara Eichau Madueño, Francesco Patti, Gilles Edan, Marc Debouverie, Jean Pelletier, Serkan Ozakbas, Maria Pia Amato, Pierre Clavelou, Pierre Grammond, Cavit Boz, Jonathan Ciron, Oliver Gerlach, Francois Grand'Maison, Jeannette Lechner-Scott, Charles Malpas, Helmut Butzkueven, Sandra Vukusic, Tomas Kalincik

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    • P0877 - Is multiple sclerosis a length-dependent central axonopathy ? Some empiric data from the TONiC study (View Presentation)

      Keyword: Observational Studies

      Roger Mills, Daniela Schlüter, Peter Diggle, Carolyn Young, Alan Tennant

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    • P0878 - Lifestyle characteristics of adherence to diet programs in an international cohort of people with MS (View Presentation)

      Keyword: Observational Studies

      Xin Lin, Nupur Nag, Sandra Neate, George Jelinek, Tracey Weiland, Steve Simpson-Yap

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    • P0879 - Long term consequences of high titre neutralizing antibodies to interferon-β in multiple sclerosis (View Presentation)

      Keyword: Observational Studies

      Nicky Dunn, Anna Fogdell-Hahn, Jan Hillert, Tim Spelman

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    • P0880 - Low discontinuation rate and side-effect burden after switching to cladribine tablets: Canadian experience from the adveva® patient support program (View Presentation)

      Keyword: Observational Studies

      Esther Dodge, Jiwon Oh, Paul Giacomini, Virginia Devonshire, Fraser Clift, Caroline Lemieux, Meritxell Sabidó, Arthur Allignol, Mark Freedman

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    • P0881 - “Mild disease course of carry-over progressive multifocal leukoencephalopathy after switching from natalizumab to ocrelizumab” (View Presentation)

      Keyword: Observational Studies

      Alyssa Toorop, Zoë Van Lierop, E. Strijbis, Charlotte Teunissen, Axel Petzold, Mike Wattjes, Frederik Barkhof, Brigit De Jong, Zoé Van Kempen, Joep Killestein

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    • P0882 - Motor Impairment in Multiple Sclerosis: Analysis from the North American Registry for Care and Research in Multiple Sclerosis (View Presentation)

      Keyword: Observational Studies

      Kottil Rammohan, David Li, June Halper, Sara Murphy, Trent Wallace, Lisa Patton, Sarah Chrisant, Chao Zheng, Seema Khurana

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    • P0883 - MRI activity and extended interval of Natalizumab dosing: a multicenter Italian study (View Presentation)

      Keyword: Observational Studies

      Marinella Clerico, Stefania Federica De Mercanti, Alessio Signori, Marco Iudicello, Cinzia Cordioli, Elisabetta Signoriello, Giacomo Lus, Simona Bonavita, Luigi Lavorgna, Giorgia Teresa Maniscalco, Erica Curti, Lorena Lorefice, Eleonora Cocco, Viviana Nociti, Massimiliano Mirabella, Damiano Baroncini, Giorgia Mataluni, Doriana Landi, Martina Petruzzo, Roberta Lanzillo, Ilaria Gandoglia, Alice Laroni, Rita Frangiamore, Arianna Sartori, Paola Cavalla, Gianfranco Costantini, Maria Pia Sormani, Ruggero Capra

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    • P0884 - MS disease modifying therapy sequencing – natalizumab to cladribine tablets – experience in 46 patients (View Presentation)

      Keyword: Observational Studies

      Tjalf Ziemssen, Iris-Katharina Penner, Torsten Wagner, Michael Huebschen, Beate Mueller, Tanja Buescher, Joachim Richter, Anita Posevitz-Fejfar

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    • P0885 - MSProDiscussTM is a useful tool to aid discussion of multiple sclerosis disease progression: Results from a large, real-world qualitative survey (View Presentation)

      Keyword: Observational Studies

      Tjalf Ziemssen, Gavin Giovannoni, Enrique Alvarez, Virender Bhan, Carrie Hersh, Olaf Hoffmann, Celia Oreja-Guevara, René Robles-Cedeño, Maria Trojano, Patrick Vermersch, Pamela Dobay, Mudeer Khwaja, Bianca Stadler, Thomas Hach, Daniela Piani-Meier, Jason Burton

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    • P0886 - Multiple Sclerosis diagnosis at USNS Comfort during the aftermath of Hurricane Maria: A Case Report (View Presentation)

      Keyword: Observational Studies

      Luis Velez, Astrid Diaz, Viviana Martinez, Ivonne Vicente, Angel Chinea

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    • P0887 - Multiple sclerosis evaluation and diagnosis may be delayed in male and African American patients (View Presentation)

      Keyword: Observational Studies

      Amy Safadi, Brian Barry, Robert Shin

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    • P0888 - Multiple Sclerosis Patients' Perceptions of Using an Accelerometer and Mobile App for Clinical Research (View Presentation)

      Keyword: Observational Studies

      Meredith Kossoff, Jesse Ritter, Jennifer Keller, Ellen Mowry, Kyra Mendez

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    • P0889 - Natural history of relapsing-remitting multiple sclerosis in a 30 years-lasting Portuguese cohort (View Presentation)

      Keyword: Observational Studies

      Daniela Ferro, Adilson Marcolino, Ana Rocha, Mafalda Seabra, Teresa Mendonça, Pedro Abreu, Joana Guimarães, Ana Macedo, Maria José Sá

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    • P0890 - Neurologic manifestations of IgG4-related disease: A single-center case series (View Presentation)

      Keyword: Observational Studies

      Michael Graber, Helly Hammer, Nicole Kamber, Lara Diem, Anke Salmen, Andrew Chan, Robert Hoepner, Christoph Friedli

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    • P0891 - Neurological manifestations of GAD-65 antibodies (View Presentation)

      Keyword: Observational Studies

      Ahmad Abulaban, Nora Abo Ghaddara, Sarah Wesley, David A. Hafler, Erin Longbrake

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    • P0892 - Ocrelizumab as an immune reconstitution therapy? A case report. (View Presentation)

      Keyword: Observational Studies

      James Hrastelj, Gillian Ingram, Rachel Smith, Shaheena Sadiq, Owen Pearson

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    • P0893 - Olfactory dysfunction in patients with relapsing-remitting multiple sclerosis treated with disease modifying therapies (View Presentation)

      Keyword: Observational Studies

      Marcin Wnuk, Leszek Drabik, Monika Marona, Joanna Szaleniec, Amira Bryll, Paulina Karcz, Justyna Kolasinska, Monika Kolasinska, Maciej Ziekiewicz, Jacek Skladzien, Tadeusz Popiela, Agnieszka Slowik

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    • P0894 - One year real-life data on efficacy, safety, and retention of Teriflunomide in Cypriot patients with Relapsing-Remitting Multiple Sclerosis (View Presentation)

      Keyword: Observational Studies

      Elena Kkolou, Theofilos Roussos, Eleni Papanicolaou, Kleopas Kleopa, Eleni Leonidou, Yiolanda-Panayiota Christou, Sakis Lambrianides, Theodoros Kyriakides, Marios Pantzaris

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    • P0895 - Outcomes from a prospective observational registry of repository corticotropin injection for the treatment of multiple sclerosis relapse (View Presentation)

      Keyword: Observational Studies

      Jeffrey Kaplan, Tamara Miller, Matthew Baker, Bryan Due, Enxu Zhao, George Wan

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    • P0896 - PANGAEA 2.0 EVOLUTION: Unraveling patient and treatment characteristics for SPMS and at risk for SPMS patients in clinical routine (View Presentation)

      Keyword: Observational Studies

      Tjalf Ziemssen, Benedict Rauser

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    • P0897 - Persistence and adherence to ocrelizumab compared with other disease-modifying therapies for multiple sclerosis for up to 18 months in the US (View Presentation)

      Keyword: Observational Studies

      Michelle Gheen, Natalie Engmann, Daniel Sheinson, Carmen Ng, Laura Julian, Gabriel Pardo

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    • P0899 - Prevalence of late-onset Multiple Sclerosis in Argentina: cross sectional study from RelevarEM (View Presentation)

      Keyword: Observational Studies

      Raul Piedrabuena, Susana Liwacki, Andres Barboza, Pedro Nofal, Marcos Burgos, Javier Hryb, Juan Rojas, Eduardo Kohler, Eduardo Knorre, Matías Kohler, Miguel Jacobo, Santiago Bestoso, Juan Viglione, Pablo Divi, Gustavo Sgrilli, Gustavo Jose, Mariano Coppola

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    • P0900 - Rabies vaccination and the risk of multiple sclerosis relapse (View Presentation)

      Keyword: Observational Studies

      Patrice Lalive

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    • P0901 - Real life efficacy and tolerability of Teriflunomide: 3 years of following in a multicentre study in Galicia (TERIGAL 2019). (View Presentation)

      Keyword: Observational Studies

      Antonio Pato, Elena Alvarez, Eva Costa, Daniel García, Ana García Pelayo, María Rodriguez, Ana Rodríguez Regal, Miguel Llaneza, Agustín Martínez, Laura Ramos, Inés Gonzalez, María Amigo, José Ramón Lorenzo González, José María Prieto González

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    • P0902 - Real world evidence of progression independent of relapsing activity among MS patients treated with Alemtuzumab. (View Presentation)

      Keyword: Observational Studies

      Eleonora Rigoni, Victoria Singh-Curry, Ashwini Nandoskar, Omar Malik, Rachel Dorsey-Campbell, Roberto Bergamaschi, Paolo Muraro, Richard Nicholas, Antonio Scalfari

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    • P0903 - Real world patterns and outcomes of seropositive autoimmune encephalitis (View Presentation)

      Keyword: Observational Studies

      Ahmad Abulaban, Nora Abo Ghaddara, Sarah Wesley, David A. Hafler, Erin Longbrake

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    • P0904 - Real-world demographics, clinical characteristics and treatment patterns in relapsing multiple sclerosis patients on disease-modifying therapy (View Presentation)

      Keyword: Observational Studies

      Tjalf Ziemssen, Anna Kurzeja, Jennifer Haas, Jessica Alexander, Maurice Driessen

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    • P0905 - Real-world experience of ocrelizumab in multiple sclerosis patients in Latin America (View Presentation)

      Keyword: Observational Studies

      Juan Rojas, Liliana Patrucco, Manuel Fruns, Jose Flores-Rivera, Edgar Carnero Contentti, Lorna Galleguillos, Ricardo Alonso, Edgardo Cristiano

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    • P0906 - Real-world Experience of Ocrelizumab initiation in a Diverse MS population (View Presentation)

      Keyword: Observational Studies

      Hamza Coban, Sarah Germaine, Ian Dimaandal, Nicholas Haberli, Charanpreet Padam, Marina Creed, Jaime Imitola

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    • P0907 - Real-world experience with Cladribine Tablets in the MSBase Registry (View Presentation)

      Keyword: Observational Studies

      Helmut Butzkueven, Tim Spelman, Suzanne Hodgkinson, Tomas Kalincik, Katherine Buzzard, Olga Skibina, Sara Eichau Madueño, Guillermo Izquierdo, Anneke Van Der Walt, Francois Grand-Maison, Ernest Butler, Julie Prevost, Pamela McCombe, Jiwon Oh, Richard Macdonell, Jeannette Lechner-Scott, Vincent Van Pesch, Pierre Duquette, Alexandre Prat, Marc Girard, Allan Kermode, Jessica Fabris And The Msbase Investigators Study Group

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    • P0908 - Real-World Experience with Ocrelizumab - a Safety and Efficacy Clinical Analysis (View Presentation)

      Keyword: Observational Studies

      Jamie Bolling, Torge Rempe, Matthew Vasquez, Carlos Vervloet Sollero, Aaron Carlson, Tirisham Gyang

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    • P0909 - Real-world experience with Ocrelizumab in the MSBase Registry (View Presentation)

      Keyword: Observational Studies

      Helmut Butzkueven, Tim Spelman, Serkan Ozakbas, Tomas Kalincik, Cavit Boz, Katherine Buzzard, Olga Skibina, Raed Alroughani, R Karabudak, Anneke Van Der Walt, Jeannette Lechner-Scott, Suzanne Hodgkinson, Guy Laureys, Liesbeth Van Hijfte, Murat Terzi, Ernest Butler, Richard Macdonell, Francesco Patti, Vincent Van Pesch, Mark Slee, Michael Barnett, Pierre Grammond, Julie Prevost, Francois Grand-Maison, Bruce Taylor, Allan Kermode, Pamela McCombe, Pierre Duquette, Alexandre Prat, Marc Girard, Sara Eichau Madueño, Guillermo Izquierdo, Aysun Soysal, José Luis Sánchez-Menoyo, Javier Sotoca, Erwan Muros-Le Rouzic, Petra Dirks

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    • P0910 - Relapse-free and NEDA status with Cladribine in a real life population: a multicentre study (View Presentation)

      Keyword: Observational Studies

      Pietro Annovazzi, Luca Prosperini, Rocco Capuano, Antonio Gallo, Jessica Frau, Eleonora Cocco, Agostino Nozzolillo, Lucia Moiola, Monica Margoni, Paola Perini, Marco Capobianco, Mauro Zaffaroni

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    • P0911 - Relapses and all-cause hospitalizations are influenced by system-level factors: Real-world evidence from the MS-CQI improvement collaborative study. (View Presentation)

      Keyword: Observational Studies

      BRANT Oliver, FALGUNI Mehta, Karen Walsh

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    • P0913 - Risks associated with wash-out duration when switching from fingolimod to cell-depleting agents (View Presentation)

      Keyword: Observational Studies

      Diana Ferraro, Pietro Iaffaldano, Tommaso Guerra, Matilde Inglese, Antonio Bertolotto, Vincenzo Brescia Morra, Mauro Zaffaroni, Massimiliano Mirabella, Giacomo Lus, Francesco Patti, Paola Cavalla, Maria Cellerino, Marco Capobianco, Francesca Vitetta, Damiano Paolicelli, Patrizia Sola, Maria Trojano

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    • P0914 - Safety and clinical effectiveness of peginterferon beta-1a for relapsing multiple sclerosis: PLEGRIDY Observational Program fourth interim results (View Presentation)

      Keyword: Observational Studies

      Christina Eavis, Marco Salvetti, Gereon Nelles, Sibyl Wray, Maria Naylor, Arman Altincatal, Achint Kumar, Nydjie Grimes, Thijs Koster

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    • P0915 - Safety and effectiveness of ocrelizumab in multiple sclerosis: a real-world study from Spain (View Presentation)

      Keyword: Observational Studies

      Angel Sempere, Leticia Berenguer-Ruiz, Amparo Burgos-San Jose, Miguel Aragones, Maria Dolores Navarro-Lopez

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    • P0916 - Safety and tolerability in patients with multiple sclerosis receiving ocrelizumab in a real-world setting – CONFIDENCE one-year interim analysis (View Presentation)

      Keyword: Observational Studies

      Mathias Buttmann, Sven Meuth, Martin Weber, Petra Dirks, Julius Eggebrecht, Stefanie Hieke-Schulz, Jost Leemhuis, Tjalf Ziemssen

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    • P0917 - Sleep-related disorders and their relationship with fatigue in patients with Relapsing-Remitting Multiple Sclerosis. (View Presentation)

      Keyword: Observational Studies

      Darío Tavolini, Carolina Mainella, María Oviedo, Silvina Micchielli, Roman Torri, Flavia Perone, Alejandro Zingale

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    • P0918 - Teriflunomide safety and efficacy in advanced progressive multiple sclerosis (View Presentation)

      Keyword: Observational Studies

      Vanessa Fernanda Moreira Ferreira, Danielle Caefer, Natalie Erlich-Malona, Brian Healy, Tanuja Chitnis, James Stankiewicz

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    • P0919 - The Canadian Prospective Cohort (CanProCo) Study to Understand Progression in Multiple Sclerosis: Rationale and Baseline Characteristics  (View Presentation)

      Keyword: Observational Studies

      Jiwon Oh, Nathalie Arbour, Fabrizio Giuliani, Shannon Kolind, Larry Lynd, Ruth Ann Marrie, Luanne Metz, Scott Patten, Alexandre Prat, Alice Schabas, Penelope Smyth, Roger Tam, Anthony Traboulsee, Voon Yong

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    • P0920 - The effect of alemtuzumab treatment in relapsing remitting multiple sclerosis: real-world data from a four-year prospective one center study. (View Presentation)

      Keyword: Observational Studies

      Sofia Sandgren, Lenka Novakova, Markus Axelsson, Clas Malmeström, Jan Lycke, Henrik Zetterberg

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    • P0921 - The impact of Latent Tuberculosis in Multiple Sclerosis management: a cohort study from a tertiary Multiple Sclerosis centre   (View Presentation)

      Keyword: Observational Studies

      Ana Novo, Inês Correia, Pedro Faustino, Carla Nunes, Carmo Macário, Lurdes Correia, José Serra, Sonia Batista, Lívia Sousa

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    • P0922 - The positive impact of dimethyl fumarate and patient services to address relapsing-remitting multiple sclerosis patients’ unmet medical needs (View Presentation)

      Keyword: Observational Studies

      Beatrix Bevernage, Marvin Rock, Noemie Dell, Michael Tempest, Jonathan Randell, Lucilla Franchetta Ortelli, Gabriele Niemczyk, Eddie Jones, Joseph Husbands, James Pike, Sean Kenny

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    • P0923 - The presence of SARS CoV2 antibodies in MS patients (View Presentation)

      Keyword: Observational Studies

      Asya Wallach, Stacy Melvin, Matthew Schiebel, Mary Picone

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    • P0924 - The prevalence of daytime sleepiness in multiple sclerosis (MS) (View Presentation)

      Keyword: Observational Studies

      Driss Tlemcani Mhandez



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    • P0925 - Therapeutic Inertia in Relapsing-Remitting Multiple Sclerosis (View Presentation)

      Keyword: Observational Studies

      Rita Rodrigues, Raquel Rocha, Gonçalo Bonifácio, Daniela Ferro, Francisco Sabença, Ana Isabel Gonçalves, Filipe Correia, Joaquim Pinheiro, José Leal Loureiro, Rui Pedro Guerreiro, José Vale, Maria José Sá, Andreia Costa

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    • P0926 - Therapeutic Practices in Multiple Sclerosis (MS) Amongst General Neurologists and MS Specialists (View Presentation)

      Keyword: Observational Studies

      Adnan Subei, Robert Bermel, Chloe Gianatasio, Wendy Cerenzia, Brian Moss

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    • P0927 - Treatment discontinuation and restart among patients with multiple sclerosis using disease-modifying therapies (View Presentation)

      Keyword: Observational Studies

      Jenna Zeringo, Robert Fox, Rina Mehta, Tim Pham, Julie Park, Kathleen Wilson, Machaon Bonafede

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    • P0928 - Treatment patterns in Relapsing-Remitting Multiple Sclerosis patients starting injectable versus oral first-line Drug Modifying Therapies (View Presentation)

      Keyword: Observational Studies

      Maria Coutinho, Patrícia Faustino, Lia Leitão, Carlos Capela, Marisa Brum, Joana Parra, João Sequeira, Ariana Barros, Cristina Araújo, Ana Sousa, Filipa Ladeira

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    • P0929 - Two-Year Interim Analysis of the TREAT-MS Alemtuzumab Study in Germany Differentiated by the Number of Previous Disease-Modifying Therapies (View Presentation)

      Keyword: Observational Studies

      Ann-Kathrin Halbes, Tjalf Ziemssen, Robin White, Ulrich Engelmann, Rocco Haase, Katja Akgün

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    • P0930 - Usage trend of oral drugs for multiple sclerosis in Argentina (View Presentation)

      Keyword: Observational Studies

      Ricardo Alonso, Berenice Silva, Maria Barbara Eizaguirre, Federico Man, Abril Lopez Bisso, Leila Cohen, Cecilia Pita, Juan Rojas, Liliana Patrucco, Edgardo Cristiano, Veronica Tkachuk, Maria Eugenia Balbuena, Edgar Carnero Contentti, Pablo Lopez, Juan Pettinicchi, Norma Deri, Jimena Miguez, agustín Pappolla, Nora Fernandez Liguori, Jorge Correale, Adriana Carrá, orlando Garcea

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    • P0931 - Using real-world data from a large, multi-specialty health care system to longitudinally phenotype multiple sclerosis (View Presentation)

      Keyword: Observational Studies

      Ariele Greenfield, Sarah Robinson, Pragati Kenkare, Katherine Gillespie, Meagan Harms, Juliet Farnan, Kimberly Christensen, Heather Law, Gregory Tranah

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    • P0932 - Vitamin D levels and clinical outcomes and quantitative MRI metrics in a real-world MS cohort (View Presentation)

      Keyword: Observational Studies

      Ahmad Mahadeen, Justin Abbatemarco, Isaac Briskin, Daniel Ontaneda

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    • P0933 -  Inhibition of protein disulfide isomerase has neuroprotective effects in a mouse model of experimental autoimmune encephalomyelitis (View Presentation)

      Keyword: Experimental Models

      M. Hossein Harirchian, Maryam Kamarehei, Sina Pejman, Sussan Kaboudanian Ardestani, Hamid Zahednasab, Masoumeh Firouzi

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    • P0934 - A novel experimental model to assess the contribution of heterogeneous nuclear ribonucleoprotein A1 (A1) mutations to neurodegeneration in MS. (View Presentation)

      Keyword: Experimental Models

      Joseph-Patrick Clarke, David Kim, Catherine Hutchinson, Michael Levin

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    • P0935 - Absence of B cells in brainstem and white matter lesions associates with a less severe disease and absence of oligoclonal bands in MS autopsy cases (View Presentation)

      Keyword: Pathogenesis – Immunology

      Nina Fransen, Brigit De Jong, Katharina Hess, Tanja Kuhlmann, Maria Vincenten, Jörg Hamann, Inge Huitinga, Joost Smolders

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    • P0936 - Active MS patients revealed a higher expression of EBV-DNA in their CD19+ cells in comparison to stable MS patients and controls (View Presentation)

      Keyword: Pathogenesis – Immunology

      Maria Chiara Monaco

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    • P0937 - Altered expression of myelin-related RNA binding proteins in a mouse model of multiple sclerosis (View Presentation)

      Keyword: Pathogenesis – Neurodegeneration

      Ali Jahanbazi Jahan-Abad, Cole Libner, Hannah Salapa, Michael Levin

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    • P0938 - An effective gene-immunotherapy for Multiple Sclerosis in mice. (View Presentation)

      Keyword: Experimental Models

      Geoffrey Keeler, Isabelle Cote, Addelynn Sagadevan, Cristina Gaddie, Brad Hoffman

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    • P0939 - Antibody titters against EBV and HHV-6A/B and expression of MSRV ENV in the serum of pregnant multiple sclerosis patients (View Presentation)

      Keyword: Pathogenesis – Immunology

      Roberto Alvarez-Lafuente, Silvia Pérez-Pérez, Juan Pablo Cuello, María L Martínez-Ginés, Beatriz Pardo-Rodríguez, Jose Manuel García-Domínguez, María Inmaculada Domínguez-Mozo, Alberto Lozano-Ros, María Ángel García-Martínez, Yolanda Higueras, Ariana Meldaña-Rivera, Haydee Goicoechea-Briceño, Amalia Tejada-Velarde, Jose Ignacio Fernandez-Velasco, Silvia Medina, Rafael Arroyo, Luisa María Villar

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    • P0940 - Anti-CD20 therapy prevents cortical demyelination in a new rat model (View Presentation)

      Keyword: Experimental Models

      Michaela Tanja Haindl, Muammer Üçal, Lennart Tögl, Benjamin Klaus, Jana Dohrmann, Milena Adzemovic, Christian Enzinger, Sonja Hochmeister

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    • P0941 - Anti-myelin oligodendrocyte glycoprotein autoantibodies trigger an Fc-Receptor and BTK-dependent proliferative response in microglia (View Presentation)

      Keyword: Pathogenesis – Role of Glia

      Kathryn Pellerin, Stephen Rubino, Jeremy Burns, Benjamin Smith, Jing Zhu, Rebecca Basile, luke Jandreski, Taylor Reynolds, Baohong Zhang, Ellen Cahir-Mcfarland, Richard Ransohoff, Tom Cameron, Michaël Mingueneau

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    • P0942 - Astrocyte Topography Throughout the Multiple Sclerosis Motor Cortex and its Relationships with Genotype and Pathological Outcome  (View Presentation)

      Keyword: Pathogenesis – Role of Glia

      Sydney Yee, Richard Yates, Margaret Esiri, Gabriele Deluca

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    • P0943 - Autofluorescence identifies two subsets of microglia in healthy brain and defines their differential modulation by aging.  (View Presentation)

      Keyword: Pathogenesis – Role of Glia

      Jeremy Burns, Bunny Cotleur, Dirk Walther, Bekim Bajrami, Stephen Rubino, Ru Wei, Nathalie Franchimont, Susan Cotman, Richard Ransohoff, Michaël Mingueneau

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    • P0944 - B-cells uptake citrullinated myelin basic protein in MS meningeal tissue: cause or consequence? (View Presentation)

      Keyword: Pathogenesis – Immunology

      Antonio Luchicchi, Karlien Doetjes, Geert Schenk, Jeroen Geurts, Bert ´t Hart

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    • P0945 - Brain choroid plexus volume in Multiple Sclerosis versus Neuromyelitis Optica Spectrum Disease (View Presentation)

      Keyword: Pathogenesis – the Blood-Brain Barrier

      Jannis Müller, Tim Sinnecker, Maria Janina Wendebourg, Regina Schlaeger, Jens Kuhle, Pascal Benkert, Tobias Derfuss, Philippe Cattin, Christoph Jud, Florian Spiess, Michael Amann, Therese Lincke, Muhamed Barakovic, Alessandro Cagol, Susanna Asseyer, Ankelien Duchow, Alexander Brandt, Klemens Ruprecht, Friedemann Paul, Nouchine Hadjikhani, Ludwig Kappos, Jens Wuerfel, Cristina Granziera, Özgür Yaldizli

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    • P0946 - CCR2+ monocytes require EMMPRIN for migration into EAE/MS brains (View Presentation)

      Keyword: Pathogenesis – Immunology

      Deepak Kaushik, Jennifer Hahn, Claudia Silva, Tina Vo, Antoine Dufour, Voon Yong

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    • P0947 - CD11c+CD88+CD317+ myeloid cells are critical mediators of persistent CNS autoimmunity (View Presentation)

      Keyword: Pathogenesis – Immunology

      Navid Manouchehriardestani, Rehana Hussain, Gregory Wu, Brian Edelson, Maxim Artyomov, Anne Cross, Ekaterina Esaulova, Richard Doelger, Petra Cravens, Nicolas Loof, Todd Eagar, Laurent Calvier, Joachim Herz, Thomas Forsthuber, Olaf Stuve

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    • P0948 - CD20+ T cells emerge from pathogenic B cell- T cell interaction (View Presentation)

      Keyword: Pathogenesis – Immunology

      Jasmin Ochs, Nitzan Nissimov, Julian Koch, Katja Grondey, Marie Freier, Silke Häusser-Kinzel, Martin Weber

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    • P0949 - Cell population analysis in a patient-derived cerebral organoid model of multiple sclerosis. (View Presentation)

      Keyword: Experimental Models

      Eric Chen, Nicolas Daviaud, Saud Sadiq

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    • P0950 - Cerebrospinal fluid IgM associates with specific inflammatory profile and disease features in early multiple sclerosis. (View Presentation)

      Keyword: Pathogenesis – Immunology

      Valentina Mazziotti, Roberta Magliozzi, Damiano Marastoni, Luigi Montibeller, Anna Pisani, Agnese Tamanti, Stefania Rossi, Francesco Crescenzo, Massimiliano Calabrese

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    • P0951 - Challenge to creation of neuromyelitis optica mice model by AQP4 peptide immunization (View Presentation)

      Keyword: Experimental Models

      Kenichi Serizawa, Shota Miyake, Haruna Tomizawa-Shinohara, Kenji Yogo, Yoshihiro Matsumoto

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    • P0952 - Characterization of age-related changes in circulating T cells in multiple sclerosis and normal controls: a pilot study (View Presentation)

      Keyword: Pathogenesis – Immunology

      Leah Zuroff, Rui Li, Koji Shinoda, Ayman Rezk, Amit Bar-Or

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    • P0953 - Damage of the subventricular zone: relation with striatal atrophy and cognitive performance in MS (View Presentation)

      Keyword: Pathogenesis – Neurodegeneration

      Aurora Zanghì, Laura Cacciaguerra, Alessandro Meani, Olga Marchesi, Massimo Filippi, Maria A. Rocca

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    • P0954 - Dectin-1 limits central nervous system autoimmunity through a non-canonical pathway (View Presentation)

      Keyword: Pathogenesis – Immunology

      Marion Deerhake, Keiko Danzaki, Makoto Inoue, Emre Cardakli, Toshiaki Nonaka, Nupur Aggarwal, William Barclay, Ru Rong Ji, Mari Shinohara

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    • P0955 - Diffuse inflammation relates to demyelination and clinical parameters in primary (PP) and secondary progressive multiple sclerosis (SP). (View Presentation)

      Keyword: Pathogenesis – the Blood-Brain Barrier

      Stephan Bramow, Helle Broholm, Jeppe Christensen, Manuela Paunovic, Betül Okutan, Melinda Magyari, Henning Laursen, Per Soerensen, Hartwig Siebner, Josa Frischer, Marina Von Essen, Hans Lassmann, Finn Sellebjerg

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    • P0956 - DNA methylation of cerebrospinal fluid cells in Multiple Sclerosis (View Presentation)

      Keyword: Pathogenesis – Immunology

      Galina Zheleznyakova, Yanan Han, Elena Ivanova, Mohsen Khademi, Fredrik Piehl, Tomas Olsson, Gavin Kelsey, Maria Needhamsen, Maja Jagodic

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    • P0957 - Does peripheral immune profile reflect intrathecal inflammation in multiple sclerosis patients at time of diagnosis? (View Presentation)

      Keyword: Pathogenesis – Immunology

      Roberta Magliozzi, Antonio Vella, Daniela Postinghel, Valentina Mazziotti, Stefania Rossi, Alice Giacomazzi, Marco Castellaro, Damiano Marastoni, Francesco Crescenzo, Vincenzo Bronte, Salvatore Monaco, Massimiliano Calabrese

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    • P0958 - Drug library screen identifies inhibitors of toxic astrogliosis (View Presentation)

      Keyword: Pathogenesis – Role of Glia

      RUTURAJ Masvekar, Peter Kosa, Christopher Barbour, Bibiana Bielekova

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    • P0959 - Dysfunction of the RNA binding protein hnRNP A1 contributes to disease progression and neurodegeneration in an animal model of multiple sclerosis  (View Presentation)

      Keyword: Pathogenesis – Neurodegeneration

      Cole Libner, Hannah Salapa, Michael Levin

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    • P0960 - Effect of systemic inflammation on repaired cortical lesions: from innate to adaptive response (View Presentation)

      Keyword: Experimental Models

      Berenice Silva, María Leal, María Farías, Juan Avalos, Esteban Miglietta, Fernando Pitossi, Carina Ferrari

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    • P0961 - Excitation-inhibition balance in multiple sclerosis: a quantification of glutamatergic and GABA-ergic synapse loss (View Presentation)

      Keyword: Pathogenesis – Neurodegeneration

      Marijn Huiskamp, Svenja Kiljan, Laura Jonkman, John Bol, Geert Schenk, Hanneke Hulst, Jeroen Geurts

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    • P0962 - Expression of Bruton’s tyrosine kinase in B cell-rich meningeal infiltrates in two models of progressive MS (View Presentation)

      Keyword: Pathogenesis – Immunology

      Hania Kebir, Guadalupe Ceja, Miles Miller, Cen Li, Michael May, Charles Vite, Molly Church, Roland Grenningloh, Ursula Boschert, Jorge Alvarez

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    • P0963 - Filtration of primary progressive MS CSF removes factors causing delayed remyelination of lysolecithin lesions (View Presentation)

      Keyword: Experimental Models

      Joseph Beaty, Taylor Shue, Anna Roselle, Jamie Wong, Saud Sadiq

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    • P0964 - Herpesvirus serology in primary progressive multiple sclerosis (View Presentation)

      Keyword: Pathogenesis – Immunology

      Roberto Alvarez-Lafuente, María Inmaculada Domínguez-Mozo, Silvia Pérez-Pérez, María Ángel García-Martínez, Yolanda Aladro, Belen Pilo, María L Martínez-Ginés, Jose Manuel García-Domínguez, Inés González-Suárez, Paula Salgado-Cámara, Carlos López De Silanes, Ignacio Casanova, Javier Sotoca, Rafael Arroyo

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    • P0965 - HGF/c-Met pathway and CD4+ T cell functions in EAE (View Presentation)

      Keyword: Experimental Models

      Patrice Lalive

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    • P0966 - How Do Exosome Enriched Fractions from Multiple Sclerosis Patients Cultured B Cells Kill Oligodendroglia (View Presentation)

      Keyword: Pathogenesis – Immunology

      Robert Lisak, Liljana Nedelkoska, Hanane Touil, Paul Stemmer, Nicholas Carruthers, leah Zuroff, Amit Bar-Or, Joyce Benjamins

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    • P0967 - Identification and Characterization of Adherence Trajectory Subgroups in Patients with MS Initiating Once- or Twice-Daily Oral Disease-Modifying Drugs (View Presentation)

      Keyword: Experimental Models

      Miriam Cisternas, Dilip Rajagopalan, Michael Leszko, Katherine Andrade, Amy Phillips

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    • P0968 - Imaging butyrylcholinesterase in multiple sclerosis (View Presentation)

      Keyword: Pathogenesis – Immunology

      Michael Thorne, Meghan Cash, G. Andrew Reid, David Luke, Darcy Burley, Ian Pottie, Sultan Darvesh

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    • P0969 - Imbalance of TNF and TNF receptors in the cerebrospinal fluid of naïve multiple sclerosis patients (View Presentation)

      Keyword: Pathogenesis – Immunology

      Roberta Magliozzi, Stefania Rossi, Francesco Pezzini, Damiano Marastoni, Mairi Pucci, Valentina Mazziotti, Francesco Crescenzo, Francesco Facchiano, Giuseppe Lippi, Richard Reynolds, Massimiliano Calabrese

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    • P0970 - Immunoelectron microscopy for ultrastructural studies of oligodendrocyte progenitors  (View Presentation)

      Keyword: Experimental Models

      Maria Jose Ulloa-Navas, José Manuel García-Verdugo, Vicente Herranz-Pérez

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    • P0971 - Immunoglobulins specific for Epstein-Barr virus proteins bind to microglia (View Presentation)

      Keyword: Pathogenesis – Immunology

      John Lindsey, Maria Hernandez, Xiurong Zhao

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    • P0972 - Impact of age on the immune system and the central nervous system in experimental autoimmune encephalomyelitis (View Presentation)

      Keyword: Pathogenesis – Immunology

      Maria Dema, Herena Eixarch, Laura Calvo-Barreiro, M. González, Mireia Castillo, Luisa María Villar, Xavier Montalban, Carmen Espejo

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    • P0973 - Impact of Epstein-Barr virus infection on CXCR3+ B-cell development: lessons learned from immunotherapies in MS (View Presentation)

      Keyword: Pathogenesis – Immunology

      Jamie Van Langelaar, Annet Wierenga-Wolf, Johnny Samijn, Caroline Luijks, Liza Rijvers, Marie José Melief, Theodora Siepman, Pieter Van Doorn, Andrew Bell, Menno Van Zelm, Helga De Vries, Peter Paul Unger, S Marieke Van Ham, Joost Smolders, Marvin Van Luijn

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    • P0974 - Is salt consumption  an envorimental risk factor for multiple sclerosis?  (View Presentation)

      Keyword: Pathogenesis – Immunology

      Sena Destan Bünül, Hüsnü Efendi

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    • P0975 - Lipid-specific oligoclonal IgM bands condition age-related changes in multiple sclerosis (View Presentation)

      Keyword: Pathogenesis – Immunology

      Carmen Picón, Amalia Tejeda-Velarde, Jose Ignacio Fernandez-Velasco, Manuel Comabella, Roberto Alvarez-Lafuente, Ester Quintana, Susana Sainz de la Maza, Enric Monreal, Noelia Villarrubia, José Carlos Álvarez-Cermeño, María Inmaculada Domínguez-Mozo, Lluís Ramió I Torrentà, Eulalia Rodríguez-Martin, Ernesto Roldán, Yolanda Aladro, Silvia Medina, Mercedes Espiño, Jaime Masjuan, Clara Matute-Blanch, María Muñoz-San Martin, Carmen Espejo, Carmen Guaza, Lucienne Costa-Frossard, Luisa María Villar

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    • P0976 - Lymphotoxin alpha overexpression in the meninges causes lymphoid-like tissue development and subsequent neurodegeneration (View Presentation)

      Keyword: Pathogenesis – Immunology

      Rachel James, Carmen Picon Munoz, Eleanor Browne, Nicholas Mazarakis, Richard Reynolds

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    • P0977 - Melatonin reduces disability in experimental autoimmune encephalomyelitis by impairing immune cells migration and entry into the CNS (View Presentation)

      Keyword: Experimental Models

      Ana Isabel Álvarez-López, Ivan Cruz-Chamorro, Guillermo Santos-Sánchez, Eduardo Ponce-España, José María Fernández-Santos, José Carmelo Utrilla Alcolea, Ignacio Bejarano-Hernando, Patricia Judith Lardone, Nuria Álvarez-Sánchez, Antonio Carrillo-Vico

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    • P0978 - Metabotropic glutamate receptors are associated with cerebellar dysfunction in multiple sclerosis (View Presentation)

      Keyword: Experimental Models

      Julia Granato, Tara Edwards, Anna Iacoangeli, Saud Sadiq

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    • P0979 - Methylome and transcriptome signature of bronchoalveolar cells from Multiple Sclerosis patients in relation to smoking (View Presentation)

      Keyword: Pathogenesis – Immunology

      Mikael Ringh, Michael Hagemann-Jensen, Maria Needhamsen, Susanna Kullberg, Jan Wahlström, Johan Grunewald, Boel Brynedal, Maja Jagodic, Tomas Ekström, Johan Öckinger, Lara Kular

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    • P0980 - MicroRNA-150 controls experimental autoimmune encephalomyelitis by regulating CD4 T cell differentiation and function (View Presentation)

      Keyword: Experimental Models

      Eliane Piket, Marie N'Diaye, Ewoud Ewing, Lottie Williams, Anna Olofsson, Lena Mrugalla, Georgios Alkis Zisiadis, Irena Lavrnja, William Nyberg, Alexander Espinosa, Lara Kular, André Ortlieb Guerreiro-Cacais, Maja Jagodic

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    • P0981 - Monitoring of encephalitogenic cells treated with nanoparticles in adoptively transferred experimental autoimmune encephalomyelitis. (View Presentation)

      Keyword: Experimental Models

      Ruth García-Hernández, Alberto Nakal-Chidiac, Alicia Sánchez-Sanz, María Rosa Aguilar Aguilar, Aranzazu Garcia-Grande, María José Coronado-Albi, Luis García-Fernández, Miryam Criado-González, Carmen Zamora Cañadas, Juan Antonio García-Merino, Antonio José Sánchez-López

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    • P0982 - MR T2-relaxation time as an indirect measure of brain water accumulation in Neuromyelitis Optica Spectrum Disorders (View Presentation)

      Keyword: Pathogenesis – the Blood-Brain Barrier

      Laura Cacciaguerra, Maria A. Rocca, Elisabetta Pagani, Marta Radaelli, Sarlota Mesaros, Vittorio Martinelli, Jovana Ivanović, Massimo Filippi

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    • P0983 - Multiple therapeutic approaches for Baló’s Concentric Sclerosis : study of 10 cases  (View Presentation)

      Keyword: Pathogenesis – Immunology

      Dimitrios Tzanetakos, Aigli Vakrakou, John Tzartos, Georgios Velonakis, Maria Eleftheria Evangelopoulos, Maria Anagnostouli, Georgios Koutsis, Efthymios Dardiotis, Efstratios Karavasilis, Panagiotis Toulas, Leonidas Stefanis, Constantinos Kilidireas

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    • P0984 - Neuron-specific activation of necroptosis signaling in multiple sclerosis cortical grey matter (View Presentation)

      Keyword: Pathogenesis – Neurodegeneration

      Carmen Picon Munoz, Rachel James, Anusha Jayaraman, Maarten Witte, Jack Van Horssen, Nicholas Mazarakis, Richard Reynolds

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    • P0985 - Obesity and Multiple Sclerosis risk. The role of Leptin (View Presentation)

      Keyword: Pathogenesis – Immunology

      Mariano Marrodan, Mauricio Farez, Maria Eugenia Balbuena, Jorge Correale

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    • P0986 - Online Medical Education Improves Knowledge of Age-Related Immune System Changes in Patients with MS Among Neurologists (View Presentation)

      Keyword: Pathogenesis – Immunology

      Thomas Finnegan, Catherine Murray, John Maeglin, Gavin Giovannoni

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    • P0987 - Pathological effects of primary progressive MS cerebrospinal fluid are antibody-mediated (View Presentation)

      Keyword: Experimental Models

      Jamie Wong, Taylor Shue, Joseph Beaty, Jonah Vernejoul, Jerry Lin, Saud Sadiq

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    • P0988 - Pentamidine as a new therapeutic strategy against Multiple Sclerosis-like pathology  (View Presentation)

      Keyword: Pathogenesis – Role of Glia

      Catarina Barros, Andreia Barateiro, Beatriz Soromenho, Afonso Basto, Dora Brites, Luís Graça, Adelaide Fernandes

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    • P0989 - PLP gene immunotherapy ameliorates disease and prevents epitope spreading in mouse models of RRMS (View Presentation)

      Keyword: Experimental Models

      Isabelle Cote, Addelynn Sagadevan, Cristina Gaddie, Geoffrey Keeler, Brad Hoffman

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    • P0990 - Pro-inflammatory cytokines and autoantibodies induce dysfunctional RNA binding protein biology in primary cortical neurons (View Presentation)

      Keyword: Pathogenesis – Neurodegeneration

      Muxue Li, Rachel Hamilton, Hannah Salapa, Michael Levin

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    • P0991 - Protective and Remyelinating Potential of Siponimod in a Xenopus Model of Demyelination and a Mouse Model of Experimental Autoimmune Encephalomyelitis (View Presentation)

      Keyword: Experimental Models

      Michael Dietrich, Christina Hecker, Elodie Martin, Dominique Langui, Michael Gliem, Bruno Stankoff, Catherine Lubetzki, Andrea Issberner, Pamela Ramseier, Christian Beerli, Claire Moebs, Catherine Afatsawo, Sarah Tisserand, Hans Peter Hartung, Marc Bigaud, Bernard Zalc, Philipp Albrecht

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    • P0992 - Psycho-thermogenic hypothesis of multiple sclerosis: Deregulation of cross-talk between adrenergic signaling and mitochondrial metabolic pathways. (View Presentation)

      Keyword: Pathogenesis – Neurodegeneration

      Tatiana Sukhomlin, Hans Westerhoff

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    • P0993 - Reconstitution of a pathogenic antibody of a unique case of human autoimmune encephalitis (View Presentation)

      Keyword: Pathogenesis – Immunology

      Manuela Paunovic, Eduardo Beltran, Emine Cesur, Joachim Malotka, Romana Höftberger, Simone Mader, Naoto Kawakami, Edgar Meinl, Klaus Dornmair, Monika Bradl, Hans Lassmann

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    • P0994 - RGC-32 regulates astrocyte differentiation during experimental autoimmune encephalomyelitis (View Presentation)

      Keyword: Experimental Models

      Alexandru Tatomir, Austin Beltrand, Dallas Boodhoo, Vinh Nguyen, Cornelia Cudrici, Tudor Badea, Violeta Rus, Horea Rus

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    • P0995 - Sarm1 knockout delays but does not confer long-term protection from axonal degeneration in experimental allergic encephalomyelitis (View Presentation)

      Keyword: Experimental Models

      Unsong Oh

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    • P0996 - Single-cell RNA-sequencing implicates venous endothelial cells as a source of neo-angiogenesis in acute and chronic EAE. (View Presentation)

      Keyword: Pathogenesis – the Blood-Brain Barrier

      Dritan Agalliu, Sanjid Shahriar, Gillian Gold, Charlotte Wayne, Heidi Stuhlman, Vilas Menon

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    • P0997 - Sphingosine 1-phosphate (S1P) inhibits astrocytic glutamate uptake through S1P receptor 2 (S1P2) (View Presentation)

      Keyword: Pathogenesis – Role of Glia

      Deepa Jonnalagadda, Yasuyuki Kihara, Richard Rivera, Jerold Chun

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    • P0998 - The immunological features of peripheral blood findings from multiple sclerosis patients sustaining NEDA-3. (View Presentation)

      Keyword: Pathogenesis – Immunology

      Misako Minote, Wakiro Sato, Tomoko Okamoto, Ryosuke Takahashi, Takashi Yamamura

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    • P0999 - The role of neuronal CXCL13 chemokine expression in Multiple Sclerosis Pathology (View Presentation)

      Keyword: Pathogenesis – Neurodegeneration

      Rachel James, Heather Jacobs, Xiaowen Zhang, Richard Reynolds

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    • P1000 - Two novel medium-throughput assays for drug screening in multiple sclerosis. (View Presentation)

      Keyword: Experimental Models

      Robert Fern, Verity Mitchener, Carlos Matute

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    • P1002 - “Don’t give up on us!”: Findings from progressive MS patients on disease-modifying therapy (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Alina Ahsan, Shelby Comito, Brian Green, Lauren Lawhon, Leslie Herbert

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    • P1003 - A cohort analysis of MS patients exposed to high-dose corticosteroids (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Marzia Fronza, Lorena Lorefice, Jessica Frau, Giuseppe Fenu, Giancarlo Coghe, Daniele Carmagnini, Michela Fois, Elisa Casaglia, Silvia Barca, Eleonora Cocco

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    • P1004 - A real-world study characterizing symptoms and impacts of fatigue in US adults with relapsing multiple sclerosis using a novel disease specific scale (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Marion Azoulai, Tiphaine Lévy-Heidmann, Valentin Morisseau, Carol Jamieson, Leigh Charvet, Lauren Krupp, Lindsey Lair

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    • P1005 - An electronic, unsupervised Patient Reported Expanded Disability Status Scale for Multiple Sclerosis (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      William Rowles, Andrew Romeo, Erica Schleimer, Patrick Barba, Wan-Yu Hsu, Refujia Gomez, Adam Santaniello, Chao Zhao, Jennifer Pearce, JB Jones, Bruce Cree, Stephen Hauser, Jeffrey Gelfand, UCSF MS EPIC Study Group, Walter Stewart, Douglas Goodin, Riley Bove

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    • P1006 - An investigation into the role and impact that carers play in consultations between healthcare professionals and people with MS (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Cassie Mackenzie, Dawn Langdon, Marja-Liisa Sumelahti, Stanca Potra, Raed Alroughani, Elisabetta Verdun Di Cantogno

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    • P1007 - Assessing the impact of fatigue, disability, depression on quality of life in adults with multiple sclerosis: a systematic review (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Nur Assyifa Fillah, Norah Alkhaldi, Nupur Nag, Sandra Neate, Steve Simpson-Yap

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    • P1008 - Brain volume loss is an important treatment attribute among RRMS patients: findings from a discrete choice experiment     (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Jenna Zeringo, Kathleen Beusterien, Jinender Kumar, Oliver Will, M. Janelle Cambron-Mellott, deMauri Mackie, Tom Tencer

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    • P1009 - Characteristics and patient-reported outcomes of patients initiating ocrelizumab in the NARCOMS Registry from 2017 to 2019 (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Michelle Gheen, Amber Salter, Samantha Lancia, Ruth Ann Marrie, Robert Fox, Natalie Engmann

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    • P1010 - Comparison of Models for Disability Accumulation on the Expanded Disability Status Scale in Multiple Sclerosis (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Jenna Zeringo, Brian Healy, Bonnie Glanz, Elyse Swallow, James Signorovitch, Kaitlin Hagan, Diego Silva, Corey Pelletier, Tanuja Chitnis, Howard Weiner

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    • P1011 - Complications after lumbar puncture: a preliminary comparative analysis on the use of atraumatic vs standard needle (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Daniele Carmagnini, Lorena Lorefice, Giuseppe Fenu, Jessica Frau, Giancarlo Coghe, Marzia Fronza, Silvia Barca, Eleonora Cocco

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    • P1012 - Coping Strategies: Seeking personalized care in Multiple Sclerosis. A patient reported measure– Coping Responses Inventory. (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Sandra Vanotti, Natalia Ciufia, Maria Barbara Eizaguirre, Aldana Marinangeli, Daniela Rodrigo, Ricardo Alonso, orlando Garcea

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    • P1013 - Dating with a diagnosis: The lived experience of people with Multiple Sclerosis. (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Kinza Tabassum, Jackie Fox, Sara Fuller, Sinéad M. Hynes

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    • P1014 - Decision Making Process in Argentinian Patients with Multiple Sclerosis (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Ricardo Alonso, Anibal Chertcoff, Maria Barbara Eizaguirre, Berenice Silva, JOHANA Bauer, Celeste Curbelo, Fátima Pagani Cassará, Veronica Tkachuk, Gastón Imhoff, Felisa Leguizamon, orlando Garcea, Adriana Carra

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    • P1015 - Demonstrating the value of a patient support program for multiple sclerosis patients prescribed cladribine tablets in Ireland at the end of year 1 (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      James Plested, Kate Morgan, Bindu Joseph, Valerie Williams, Marie Kelly

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    • P1016 - Designing of a multicenter, non-interventional study to assess subjective disease perception in early-stage relapsing-remitting multiple sclerosis (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Susana Sainz de la Maza, Elena García-Arcelay, Mónica Borges, Victoria Sánchez-Menéndez, Cristina Garcia-Bernaldez, Jorge Mauriño, Gustavo Saposnik, Tamara Castillo-Trivino

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    • P1017 - “Development and Validation of a New Questionnaire for Assessing Psychological Coping in Multiple Sclerosis Patients.” (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Zacharo Panagopoulou, Artemios Artemiadis, George P. Chrousos, Christina Darviri, Maria Anagnostouli

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    • P1018 - Differences in perceptions of neurologists and patients about the challenges and outcomes in Multiple Sclerosis. (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Cássia Elisa Marin, Dagoberto Callegaro, Marco Aurélio Lana-Peixoto, Óscar Fernández, Antônio Pereira Gomes Neto, Cláudia Cristina Ferreira Vasconcelos, José Artur Costa D’almeida, Marcus Vinícius Magno Gonçalves, Maria Fernanda Mendes, Mônica Koncke Fiuza Parolin, Osvaldo Nascimento, Paulo Diniz Gama, Rafael Paternó Castello Dias-Carneiro, Ronaldo Maciel Dias, Alfredo Damasceno, Jefferson Becker

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    • P1019 - Discordant patient and provider perceptions of care and shared decision-making practices in multiple sclerosis (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Rasha Alam, Robert Bermel, Cherilyn Heggen, Jeffrey Carter, Tamar Sapir

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    • P1020 - Disease perception and its determinants in Relapsing-Remitting Multiple Sclerosis patients (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Ricardo Racha-Pacheco, Ana Rita Silva, Helena Felgueiras, Ana Isabel Gonçalves, Andreia Fernandes, Bruna Meira, Diana Melância, José Rosa, Maria Teresa Silvério, Ana Macedo

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    • P1021 - Does the WHODAS 2.0 comprehensively measure disability in multiple sclerosis? (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Roger Mills, Alan Tennant, Carolyn Young

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    • P1022 - Dutch registry (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Kitty Harrison

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    • P1023 - Early experience engaging patients in the use of a mobile application for tracking multiple sclerosis. (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      JB Jones, Xiaowei Yan, Jacqueline Liu, Ivelina Popova, Diamonne Mitchell, Michael Lindemann, Mike Baker, Jens Schjodt-Eriksen, Laura Julian

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    • P1024 - Economic impact of the Secondary Progressive Multiple Sclerosis in Spain: Interim analysis of the DISCOVER study (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Celia Oreja-Guevara, Jordi Río, Jose Ramón Ara Callizo, Miguel Angel Hernández Pérez, Julia Gracia Gil, Lluís Ramió I Torrentà, Belen Pilo De La Fuente, Ana María Alonso Torres, Sergio Martínez-Yélamos, Francisco Gascón Giménez, Sara Eichau Madueño, Bonaventura Casanova-Estruch, María Luisa Martínez Ginés, Marta Luisa Aguado Valcárcel, José Enrique Martínez Rodríguez, Ana María López Real, Carlos López De Silanes, Vicente González Quintanilla, Yasmina El Berdei Montero, Andrés Labiano, Moisés Garcés Redondo, Lucienne Costa-Frossard, Juan Antonio García Merino, Fernando Castellanos Pinedo, Carmen Muñoz Fernández, Virginia Meca-Lallana, Tamara Castillo-Trivino, Alfredo Ródríguez-Antiguedad, Joaquín Peña Martínez, José María Prieto González, Dulce María Solar Sánchez, Inmaculada Pérez Molina, Eduardo Agüera Morales, Nicolás Herrera Varo, José Meca-Lallana

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    • P1025 - Effects of general nutrition vs small group education on dietary changes of individuals living with multiple sclerosis. (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Zoe Edwards, Tiffany Malone, John Schafer, Brian Hutchinson

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    • P1026 - Employment outcomes in multiple sclerosis (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Michael Jaworski, Curtis Wojcik, Margaret Youngs, Mahmut Unverdi, Tom Fuchs, Bianca Weinstock-Guttman, Michael Dwyer, Ralph Benedict

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    • P1027 - Establishing Meaningful Change Threshold in Multiple Sclerosis related Fatigue on Fatigue Symptoms & Impacts Questionnaire-Relapsing MS (FSIQ-RMS) (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Stacie Hudgens, Neli Boyanova1, Evan Davies, Carol Jamieson, Alexander Keenan

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    • P1028 - Evolution of Mental Health in Multiple Sclerosis: a longitudinal perspective (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Irene Gil-González, Agustín Martín-Rodríguez, Farrah Mateen, María Ángeles Pérez-San-Gregorio

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    • P1029 - Examining the relationship between the Multiple Sclerosis Resiliency Scale and the Five Factor Model of Personality (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Elizabeth Gromisch, Aaron Turner, Lindsay Neto, Frederick Foley

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    • P1030 - Exploring factors that impact on quality of life: coping strategies. (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Maria Román, Camila Diven Arguello, Cecilia Yastremiz, Angeles Merino, Berenice Silva, Cecilia Pita, Sandra Vanotti, orlando Garcea

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    • P1031 - Exploring the relevance and validity of wellbeing measures that can be used in cost-effectiveness analysis in the context of multiple sclerosis (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Elizabeth Goodwin, Colin Green, Kate Boddy, Jennifer Freeman, Sarah Thomas, Jeremy Chataway, Annie Hawton

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    • P1032 - Feelings of depression, pain and walking difficulties have the largest impact on the quality of life of people with MS, irrespective of MS phenotype (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Yan Zhang, Ingrid Van Der Mei, Bruce Taylor

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    • P1033 - Health-related quality of life in relapsing multiple sclerosis patients from Argentina: impact of clinical features and coping strategies (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Edgar Carnero Contentti, Ricardo Alonso, Pablo Lopez, Maria Barbara Eizaguirre, Santiago Tizio, Veronica Tkachuk, Juan Criniti, Juan Pettinicchi, alejandro Caride

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    • P1035 - Impact of Natalizumab and Other High Efficacy Disease-Modifying Therapies on Productivity Loss in Multiple Sclerosis: A Systematic Literature Review. (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Zarmina Khankhel, Iris Brewer, Ayo Adeyemi, Kelicia Daniels, Khalil Jomaa

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    • P1036 - Impact of natalizumab on quality of life in a real-world cohort of patients with multiple sclerosis: results from MS PATHS (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Christina Eavis, Carrie Hersh, Bernd Kieseier, Carl De Moor, Deborah Miller, Denise Campagnolo, James Williams, Kathryn Fitzgerald, Kuangnan Xiong, Marisa McGinley, Megan Hyland, Richard Rudick, Tjalf Ziemssen, Irene Koulinska

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    • P1037 - Impact of remoteness on patient-reported outcomes in Australians with multiple sclerosis (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Jing Chen, Hasnat Ahmad, Bruce Taylor, Andrew Palmer, Ingrid Van Der Mei

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    • P1038 - Improved or maintained employment status in natalizumab-treated relapsing-remitting multiple sclerosis patients in the TYSABRI Observational Program (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Christina Eavis, Gisela Kobelt, Maria Trojano, Tim Spelman, Helmut Butzkueven, Ludwig Kappos, Heinz Wiendl, Shirley Liao, Carlos Acosta, Pei-Ran Ho, Stephanie Licata

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    • P1039 - Improvements in patient-reported SymptoMScreen scores among ocrelizumab-treated patients with RRMS: 2-year results from the CASTING clinical trial (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Amber O'Connor, Ilya Kister, Gary Cutter, Regine Buffels, Susanne Clinch, T Kuenzel, Patrick Vermersch

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    • P1040 - Lack of association between sexual dysfunction and spinal cord pathology in women with multiple sclerosis (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Klara Novotna, Lucie Friedova, Jiri Motyl, Manuela Vaneckova, Dana Horakova, Michaela Andelova

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    • P1041 - Longitudinal Changes in Expanded Timed Get Up and Go (ETGUG) and its Association with Patient-Reported Outomes and Other Measures of Disability (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Katelyn Kavak, Caila Vaughn, Karen Zakalik, Charlene Tymorek, Bianca Weinstock-Guttman

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    • P1042 - Mental Health in Multiple Sclerosis: influence of clinical and demographic variables (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Irene Gil-González, María Ángeles Pérez-San-Gregorio, Agustín Martín-Rodríguez

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    • P1043 - Patient coaching to optimize management of delayed-release dimethyl fumarate-associated gastrointestinal events and flushing: Five years of experience (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Gabriele Niemczyk, Yvonne Begus-Nahrmann, Sarah Rolfes, Henrik Rosenström, Maria-Theresa Grundler, Mathias Mäurer

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    • P1044 - Patient demographics and disease characteristics predict likelihood of clinical benefit on patient-reported outcome measures in multiple sclerosis (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Jacob Leary, Stefan Sillau, Brandi Vollmer, Kavita Nair, Timothy Vollmer

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    • P1045 - Predicting fall risk in persons with Multiple Sclerosis utilizing the 12-Item Multiple Sclerosis Walking Scale (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Heather Delmastro, Elizabeth Gromisch, Helen Dawes, Gabriele Deluca, Robert Krug, Anton Pick, Jennifer Ruiz

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    • P1046 - Psychometric validation of the Expanded Disability Status Scale in neuromyelitis optica spectrum disorder (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Enya Lucas, Gene Wallenstein, Cristina Costantino, Thomas Kuenzel, Daniela Stokmaier, Elisabetta Damonte, Gaelle Klingelschmitt, H.-Christian Von Büdingen

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    • P1047 - Quality of life (QoL) in treatment-refractory, disabled, multiple sclerosis (MS) during long-term repeated, alemtuzumab (ALE) as assessed by SF-36 (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Dmitriy Carrigan, Katherine Geist, Daniel Kantor, Samuel Hunter

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    • P1048 - Quality of life and economic burden of fatigue in people with multiple sclerosis: a systematic literature review (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Alexander Keenan, Abril Oliva Ramirez, Olivia Kalau, Lucas Cohen, Evelyn Worthington, Sumeet Singh

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    • P1049 - "Quality of life in multiple sclerosis. Beyond disability: Resilience, fatigue, anxiety and depression as determinants" (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Daissy Mora Cuervo, Cristiane Camargo, Douglas Nakata, Marlise De Castro Ribeiro, Cassiano Teixeira

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    • P1050 - Quantifying the patient´s perspective in neuromyelitis optica spectrum disorders: Design of a multicenter, non-interventional study (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      José Meca-Lallana, Daniel Prefasi , Bonaventura Casanova-Estruch, Carmen Calles, Albert Saiz, Inés González-Suárez, María L Martínez-Ginés, Luis Querol, Sabas Boyero, Lucienne Costa-Frossard, José María Prieto González, Lucía Forero, Virginia Meca-Lallana, Lucía Romero-Pinel, Angel Sempere, Cristina Garcia-Bernaldez, Jorge Mauriño

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    • P1051 - Real world practice patterns and patient experiences related to off-site therapy infusions in Multiple Sclerosis (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Benjamin Greenberg, Brooke McCartney, Larissa Jarzylo, Cherilyn Heggen, Jeffrey Carter, Tamar Sapir

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    • P1052 - Real-world patient-level costs of administering infusion disease-modifying drugs: a US retrospective claims database analysis (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Chris Kozma, Nancy Roberts, Amy Phillips

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    • P1053 - "Resilience in multiple sclerosis relationship with disability, fatigue, anxiety, depression and cognition" (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Daissy Mora Cuervo, Cassiano Teixeira, Cristiane Camargo, Marlise De Castro Ribeiro, Douglas Nakata

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    • P1054 - Sexual dysfunction in multiple sclerosis: who is at risk? (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Patrick Altmann, Fritz Leutmezer, Katharina Leithner, Tobias Monschein, Tobias Zrzavy, Markus Ponleitner, Miranda Stattmann, Paulus Rommer, Gudrun Zulehner, Klaus Berek, Thomas Berger, Gabriel Bsteh

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    • P1055 - Sleep disorders and quality of life in patients with Relapsing-Remitting Multiple Sclerosis (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Darío Tavolini, Carolina Mainella, María Oviedo, Silvina Micchielli, Roman Torri, Flavia Perone, Alejandro Zingale

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    • P1056 - Student Outreach Programs as Strategies to Address MS Workforce Shortages in the United States: Results Across 3 States (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Stephanie Teixeira-Poit, Alicia Flach, Paige Dalton, Prudence Plummer, Bryan Walker, Lynette Coleman, Heather Kane, Suma Shah, Mark Skeen, Erin Burkill, Erica Gaskins, Angela Trammell, William Jarrett, Carrie Bravinder, Mona Bostic

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    • P1057 - The Dutch MS Patient Voice Survey: impact of disease on daily life. (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      jan Muis, chris Schouten, Ellemieke De Wolf, Leonoor Avis, Lianne Hoeijmakers, Anouk Buurman

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    • P1058 - The Dutch MS Patient Voice Survey: Impact of Multiple Sclerosis on daily life activities; characteristics of disease phenotype and treatment (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      jan Muis, chris Schouten, Ellemieke De Wolf, Leonoor Avis, Lianne Hoeijmakers, Anouk Buurman

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    • P1059 - The effectiveness of mindfulness on quality of life in people with multiple sclerosis: a systematic review. (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Xirun Yang, Sheraya De Silva, Steve Simpson-Yap, Sandra Neate, George Jelinek, Nupur Nag

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    • P1060 - The impact of invisible symptoms on self-perception, relationships, work and healthcare interactions from the perspectives of people with MS (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Megan Kirkland, Caitlin Newell, Katie Wadden, Michelle Ploughman

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    • P1061 - The interpretation and clinical application of the PROMIS® SF v1.0 - Fatigue (MS) 8b: a PROMIS short form for assessing fatigue in multiple sclerosis (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Paul Kamudoni, Jeffrey Johns, Karon Cook, Rana Salem, Christian Henke, Sam Salek, Jana Raab, Rod Middleton, Pavle Repovic, Kevin Alschuler, Gloria Von Geldern, Annette Wundes, Dagmar Amtmann

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    • P1062 - The validity and applicability of a new PROMIS® physical function short form for use in relapsing and progressive multiple sclerosis (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Paul Kamudoni, Dagmar Amtmann, Jeffrey Johns, Karon Cook, Rana Salem, Sam Salek, Jana Raab, Rod Middleton, Pavle Repovic, Kevin Alschuler, Gloria Von Geldern, Annette Wundes, Christian Henke

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    • P1063 - Treatment persistence and adherence to Ocrelizumab in the real-world setting- an ad-hoc analysis of the CONFIDENCE study (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Kiran Tailor, Sven Meuth, Mathias Buttmann, Martin Weber, Petra Dirks, Julius Eggebrecht, Natalie Joschko, Jost Leemhuis, Michael Martinec, Erwan Muros-Le Rouzic, Kelly A Zalocusky, Tjalf Ziemssen

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    • P1064 - Treatment Preferences of Patients with Relapsing Multiple Sclerosis: A Discrete Choice Experiment (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Tatiana Scherz, Neli Boyanova1, Anne Brooks, Gin Nie Chua, Andrea Beyer, Bennett Levitan, Brian Hennessy, Tommi Tervonen

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    • P1065 - Treatment Satisfaction Across Age Groups in Patients Who Switched to Teriflunomide: Analysis of the Real-world Teri-PRO Study (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Cameron Duvall, Patricia Coyle, Ralf Gold, Jérôme De Seze, Bhupendra Khatri, Bassem Yamout, Yelena Pyatkevich, Elizabeth Poole, Patrick Vermersch

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    • P1066 - Treatment satisfaction in patients with highly-active relapsing multiple sclerosis treated with cladribine tablets: CLARIFY-MS study interim analysis (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Esther Dodge, Bruno Brochet, Raymond Hupperts Raymond Hupperts, Dawn Langdon, Alessandra Solari, Fredrik Piehl, Jeannette Lechner-Scott, Xavier Montalban, Krzysztof Selmaj, Martin Vališ, Konrad Rejdak, Eva Kubala Havrdová, Franscesco Patti, Nektaria Alexandri, Axel Nolting, Birgit Keller

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    • P1067 - Understanding the patient and clinician perspective of ideal treatments for multiple sclerosis via group concept mapping (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Jenna Zeringo, Barry A. Singer, Amy Howerter, Shannon Keith, Rina Mehta, Tim Pham, Helen Doll

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    • P1068 - Use of disease modifying therapies for improved quality of life among progressive MS patients (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Alina Ahsan, Shelby Comito, Brian Green, Lauren Lawhon, Leslie Herbert

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    • P1069 - Value-added benefits of a nurse/pharmacy-led service for patients with multiple sclerosis treated over 2 years with cladribine tablets in the UK (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      James Plested, Kate Morgan, Karen Vernon, Mavis Ayer

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    • P1070 - Age at disease onset influences grey matter and white matter integrity in MS (View Presentation)

      Keyword: Pediatric MS

      Raffaello Bonacchi, Alessandro Meani, Elisabetta Pagani, Massimo Filippi, Maria A. Rocca

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    • P1071 - Central Vein Sign in Pediatric Multiple Sclerosis and MOG Antibody Associated Disease. (View Presentation)

      Keyword: Pediatric MS

      Kimystian Harrison, Cristina Gaudioso, S. Dunham, Victoria Levasseur, Natalie Schanzer, Amber Salter, Manu Goyal, Soe Mar

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    • P1072 - Cerebellar grey matter lesions are common in pediatric multiple sclerosis at clinical onset. (View Presentation)

      Keyword: Pediatric MS

      Monica Margoni, Silvia Franciotta, Davide Poggiali, Alice Riccardi, Francesca Rinaldi, Margherita Nosadini, Stefano Sartori, Maria Giulia Anglani, Francesco Causin, Paola Perini, Paolo Gallo

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    • P1073 - Clinical Experience with Fingolimod in Pediatric Multiple Sclerosis Patients (View Presentation)

      Keyword: Pediatric MS

      Virginia Meca-Lallana, Clara Aguirre, Carolina Díaz, Veronica Cantarin, Beatriz Del Río, Jose Vivancos

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    • P1074 - Comparison of Treatment Choices in a Single Center Pediatric Onset Multiple Sclerosis Registry (View Presentation)

      Keyword: Pediatric MS

      Nazire Pinar Acar Ozen, Ismail Solmaz, Safak Parlak, Kader Karli Oguz, Aslı Tuncer, Banu Anlar

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    • P1075 - Early clinical and MRI predictors of long-term disability in pediatric multiple sclerosis patients   (View Presentation)

      Keyword: Pediatric MS

      Ermelinda De Meo, Raffaello Bonacchi, Lucia Moiola, Francesca Sangalli, Gloria Dalla Costa, Bruno Colombo, Vittorio Martinelli, Maria A. Rocca, Maria Pia Amato, Massimo Filippi

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    • P1076 - Effect of Rituximab on Immunoglobulin levels in Pediatric Multiple Sclerosis Patients (View Presentation)

      Keyword: Pediatric MS

      Natasha Mehta, Alfred Balasa, Nikita Shukla, Kristen Fisher, Timothy Lotze

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    • P1077 - Evaluating visual evoked cortical magnetic responses in youth with demyelination (View Presentation)

      Keyword: Pediatric MS

      Laura Kim, Elizabeth Pang, Bryan Maguire, Cecilia Jobst, Giulia Longoni, Donald Mabbott, E. Ann Yeh

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    • P1078 - Obesity in pediatric onset multiple sclerosis: a French cohort study (View Presentation)

      Keyword: Pediatric MS

      Pauline Milles, Thomas Tully, Gianpaolo De Filippo, Kumaran Deiva

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    • P1079 - Optic nerve head volume decreases in pediatric multiple sclerosis but not in pediatric MOG-related disorders (View Presentation)

      Keyword: Pediatric MS

      Matsanga Leyila Kaseka, Giulia Longoni, Tara Berenbaum, Ella Maria Kadas, Sunil Yadav, Alexander Brandt, E. Ann Yeh

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    • P1080 - Pediatric optic neuritis: Case series of a Neuropediatrics consultation (View Presentation)

      Keyword: Pediatric MS

      Raquel Rocha, Ernestina Santos, Raquel Samões, Ana Martins Da Silva, Sónia Figueiroa

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    • P1081 - Social networks in pediatric multiple sclerosis are associated with academic performance (View Presentation)

      Keyword: Pediatric MS

      Wendy Vargas, Seth Levin, Michael Glendinning, Kaho Onomichi, MIcky Bacchus, Brenda Banwell, Phillip De Jager

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    • P1082 - Therapeutic Response in Pediatric Neuromyelitis Optics Spectrum Disorder (View Presentation)

      Keyword: Pediatric MS

      Raffaella Umeton, Michael Waltz, Greg Aaen, Leslie Benson, Mark Gorman, Manu Goyal, Jennifer Graves, Yolanda Harris, Lauren Krupp, Timothy Lotze, Soe Mar, Jayne Ness, Mary Rensel, Teri Schreiner, Jan-Mandelt Tillema, Shelly Roalstad, Moses Rodriguez, John Rose, Emmanuelle Waubant, Bianca Weinstock-Guttman, T. Charles Casper, Tanuja Chitnis

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    • P1083 - Youth with Multiple Sclerosis have Low Levels of Physical Fitness (View Presentation)

      Keyword: Pediatric MS

      Samantha Stephens, Tara Berenbaum, Robert Motl, Marcia Finlayson, E. Ann Yeh

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    • P1084 - Adherence to OnabotulinumtoxinA Treatment in Multiple Sclerosis Patients with Spasticity from the ASPIRE Study (View Presentation)

      Keyword: Rehabilitation and Comprehensive Care

      Monica Elmore, Alberto Esquenazi, Wuwei Feng, George Wittenberg, Philippe Gallien, Alessio Baricich, Kristina Fanning, Aleksej Zuzek, Gerard Francisco, Daniel Bandari

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    • P1085 - An innovative “Doodle” drawing tool for creative cognitive-motor training in patients with multiple sclerosis (View Presentation)

      Keyword: Rehabilitation and Comprehensive Care

      Michal Greenberg Abrahami, Anat Achiron

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    • P1086 - Botulinum toxin injections in multiple sclerosis versus post-stroke spasticity (View Presentation)

      Keyword: Symptom Management

      Alessandro Dinoto, Arianna Sartori, Giulia Mazzon, Paola Polverino, Marta Cheli, Maria Elisa Morelli, Fulvio Pasquin, Alessio Bratina, Antonio Bosco, Paolo Manganotti

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    • P1087 - Characterizing GI events in early versus recent dimethyl fumarate cohorts at two large MS centers. (View Presentation)

      Keyword: Symptom Management

      Kyle Smoot, Enrique Alvarez, Chiayi Chen, Brandi Vollmer, Tamela Stuchiner, Lois Grote

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    • P1088 - Circuit class therapy in patients with Relapsing-Remitting Multiple Sclerosis (View Presentation)

      Keyword: Rehabilitation and Comprehensive Care

      Jan Kolcava, Jan Kočica, Michaela Musilova, Filip Dosbaba, Jitka Kratochvílová, Dagmar Krizova, Pavel Stourac

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    • P1089 - Depressive Symptoms and Suicidal Ideation in Progressive Multiple Sclerosis Compared to Relapsing-Remitting Multiple Sclerosis (View Presentation)

      Keyword: Symptom Management

      Lindsey Knowles, Elizabeth Esselman, Aaron Turner, Kala Phillips, Tracy Herring, Kevin Alschuler, Dawn Ehde

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    • P1090 - Differences in correlates of fatigue between relapsing and progressive forms of multiple sclerosis (View Presentation)

      Keyword: Symptom Management

      Tracy Herring, Kevin Alschuler, Lindsey Knowles, Whitney Morean, Kala Phillips, Aaron Turner, Dawn Ehde

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    • P1091 - Effect of BDNF Val66Met polymorphism on motor recovery after rehabilitation in progressive MS (View Presentation)

      Keyword: Rehabilitation and Comprehensive Care

      Antonino Giordano, Ferdinando Clarelli, Laura Ferre', Elisabetta Mascia, Silvia Santoro, Melissa Sorosina, Mauro Comola, Giancarlo Comi, Massimo Filippi, Letizia Leocani, Federica Esposito

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    • P1092 - Effect of Dalfampridine on functional systems and its impact on Expanded Disability Status Scale (View Presentation)

      Keyword: Symptom Management

      Gary Alvarez Bravo, Lluís Ramió I Torrentà, René Robles Cedeño, Ester Quintana, Jordi Gich, Marina González

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    • P1094 - Effect of nabiximols cannabinoid oromucosal spray on depressive symptoms, suicidality, and cognition in patients with multiple sclerosis (MS) (View Presentation)

      Keyword: Symptom Management

      John Deluca, Dawn Langdon, Joris Berwaerts, Joanne Wagner, Matthew Derosa

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    • P1095 - Effectiveness of a cognitive behavioral program for fatigue (FACETS +) in 110 French patients with Multiple Sclerosis : a randomized, controlled trial (View Presentation)

      Keyword: Symptom Management

      Fanny Hamelin, Marie Claire Gay, Sarah Thomas, Peter Thomas, Olivier Heinzlef, Frederic Barbot, Marie Blanchère

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    • P1096 - Evaluating Effects of Global Proprioceptive Resonance on Gait in Multiple Sclerosis with Kinetic and Electromyography  (View Presentation)

      Keyword: Rehabilitation and Comprehensive Care

      Su-Chun Huang, Gloria Dalla Costa, Marco Pisa, Davide Talarico, Andrea Tettamanti, Giancarlo Comi, Letizia Leocani

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    • P1097 - Femoral neck bone loss and increased fracture risk in people with progressive MS compared to matched controls. (View Presentation)

      Keyword: Rehabilitation and Comprehensive Care

      Augustine Devasahayam, Sarah Simms, Wendy Lasisi, Elizabeth Wallack, Liam Kelly, Michelle Ploughman

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    • P1098 - Frequency and determinants of falls in persons with multiple sclerosis without a clinical disability (View Presentation)

      Keyword: Rehabilitation and Comprehensive Care

      Zuhal Abasıyanık, turhan Kahraman, Ozge Ertekin, Cavid Baba, Serkan Ozakbas



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    • P1099 - Functional improvement gained using the HAL® Exoskeleton Robotic Device in the Progressive MS vs Non- MS populations: An Interim Analysis  (View Presentation)

      Keyword: Rehabilitation and Comprehensive Care

      Angeli Mayadev, James Bowen, James Scalan, Kim Kobata, Ziadee Cambier, Stephanie Babiarz, Jens Chapman

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    • P1100 - Identifying gaps in knowledge, skills and confidence among MS specialists to facilitate improved MS care (View Presentation)

      Keyword: Rehabilitation and Comprehensive Care

      Klaus Schmierer, Morgan Peniuta, Jiwon Oh, Thomas Leist, Patrice Lazure, Sophie Péloquin

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    • P1101 - Information needs about bladder dysfunction in people with multiple sclerosis (View Presentation)

      Keyword: Rehabilitation and Comprehensive Care

      Insa Schiffmann, Christoph Heesen



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    • P1102 - Manual Dexterity Improves with Cognitive Remediation in Relapsing but not in Progressive Multiple Sclerosis (View Presentation)

      Keyword: Rehabilitation and Comprehensive Care

      Giuseppina Pilloni, Michael Shaw, Kathleen Sherman, Lauren Krupp, Leigh Charvet

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    • P1103 - Moderators of improvements in fatigue impact following a self-management intervention in multiple sclerosis (View Presentation)

      Keyword: Rehabilitation and Comprehensive Care

      Lindsey Knowles, Cinda Hugos, Michelle Cameron, Jodie Haselkorn, Dennis Bourdette, Aaron Turner

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    • P1104 - Pain in ambulatory people with multiple sclerosis and self-reported spasticity (View Presentation)

      Keyword: Rehabilitation and Comprehensive Care

      Nikita Sajeev, Sandra Joos, Michelle Cameron, Julia Norton, Cinda Hugos

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    • P1105 - Polypharmacy in MS: Correlations with pain, fatigue, and mood. (View Presentation)

      Keyword: Symptom Management

      Joanie Thelen, Sara Baker, Jared Bruce, Amanda Thuringer, Muhammad Nashatizadeh, Sharon Lynch

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    • P1106 - Postprandial somnolence in multiple sclerosis: the invisible is real. (View Presentation)

      Keyword: Symptom Management

      Tatiana Christmas, Maddalena Ardissino, Neena Singh, Kimberley Allen-Philbey, Gavin Giovannoni, Saúl Reyes

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    • P1107 - Proactively evaluating and treating changes in function in people with multiple sclerosis: the CoachMS pilot study (View Presentation)

      Keyword: Symptom Management

      Valerie Block, Arpita Gopal, William Rowles, Chu-Yueh Guo, Jeffrey Gelfand, Riley Bove

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    • P1109 - Safety and efficacy of nabiximols in patients with multiple sclerosis-associated spasticity: post hoc analyses of a controlled enrichment design study (View Presentation)

      Keyword: Symptom Management

      Aliza Ben-Zacharia, Joris Berwaerts, Daniel Checketts, Kate Nichol, Joanne Wagner, Jerry Wolinsky, Matthew Derosa

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    • P1110 - The impact of lower limb strength on walking in persons with Multiple Sclerosis: a preliminary analysis (View Presentation)

      Keyword: Rehabilitation and Comprehensive Care

      Heather Delmastro, Helen Dawes, Gabriele Deluca, Robert Krug, Anton Pick, Jennifer Ruiz

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    • P1111 - Timely Intervention, Monitoring and Education MATTERS in MS (TIME MATTERS in MS): global piloting of the MS Brain Health quality improvement tool (View Presentation)

      Keyword: Rehabilitation and Comprehensive Care

      David Docherty, Jeremy Hobart, Helmut Butzkueven, Jodi Haartsen, Timothy Vollmer, Tjalf Ziemssen, Thirusha Lane, Gavin Giovannoni

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    • P1112 - Transcranial Direct Current Stimulation (tDCS) Results in Lasting Reduction in MS-Related Fatigue (View Presentation)

      Keyword: Symptom Management

      Lillian Walton Masters, Giuseppina Pilloni, Marco Muccio, Yulin Ge, Lauren Krupp, Leigh Charvet

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    • P1113 - Underutilization of Physical Therapy Resources for Symptomatic Women with MS During and Following Pregnancy (View Presentation)

      Keyword: Symptom Management

      Valerie Block, Olivia Mestas, Annika Anderson, Jessica Singh, Leah Wylie, Chu-Yueh Guo, Ari Green, Jeffrey Gelfand, Riley Bove

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    • P1114 - Using technology to empower patients to manage and track symptoms of MS (View Presentation)

      Keyword: Symptom Management

      Alicia Zambri, Elaine Rudell, Patty Peterson, Andrea Griffin, Michele Ingram, Tarjani Agrawal, Phd, James Bowen

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    • P1115 - A first characterization of placenta-derived extracellular vesicles in patients with multiple sclerosis. (View Presentation)

      Keyword: Reproductive Aspects and Pregnancy

      Serena Martire, Francesca Montarolo, Michela Spadaro, Simona Perga, Luca Marozio, Federica Frezet, Stefania Bruno, Giulia Chiabotto, Antonio Bertolotto, Maria Ludovica Sforza, paola Valentino

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    • P1116 - Binge alcohol consumption in murine models of Multiple Sclerosis leads to sex-specific disease development.  (View Presentation)

      Keyword: Gender Differences, Hormones and Sex Chromosomes

      Sam Bazzi, Blaine Caslin, Marissa Raskin, Aditi Karmakar, Kailey Mohler, Cole Maguire, Esther Melamed

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    • P1117 - Clinical and radiologic disease activity in pregnancy and postpartum in multiple sclerosis  (View Presentation)

      Keyword: Reproductive Aspects and Pregnancy

      Annika Anderson, Krysten Krysko, Alice Rutatangwa, Tanya Krishnakumar, Chelsea Chen, William Rowles, Maria Houtchens, Riley Bove

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    • P1118 - Cumulative update on pregnancy outcomes after fingolimod treatment in patients with multiple sclerosis (View Presentation)

      Keyword: Reproductive Aspects and Pregnancy

      Lisa M. Prach, Alan Moore, Bita Rezaallah, Gregor McBride, Imran Ali Khan, Morgane Guennec, Alit Bhatt, Yvonne Geissbuehler, Sandra Lopez Leon, Sandra Vukusic, Helmut Butzkueven, Hugh Tilson, Thomas M. Macdonald, Kerstin Hellwig, Ashwini Patil

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    • P1119 - Disease activity in patients with multiple sclerosis treated with alemtuzumab due to a pregnancy desire (View Presentation)

      Keyword: Reproductive Aspects and Pregnancy

      Paula Tagliani, Anka Vidal-Jordana, Ana Zabalza, Georgina Arrambide, Breogán Rodríguez-Acevedo, Jordi Río, Íngrid Galán, Joaquín Castilló, Luciana Midaglia, Alvaro Cobo Calvo, Manuel Comabella, Carlos Nos, Cristina Auger, Alex Rovira, Jaume Sastre-Garriga, Xavier Montalban, Mar Tintore

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    • P1120 - Disparities in access to health care for women with multiple sclerosis in Argentina (View Presentation)

      Keyword: Gender Differences, Hormones and Sex Chromosomes

      Juan Rojas, Juan Pettinicchi, Pablo Lopez, Juan Criniti, Ricardo Alonso, orlando Garcea, Maria Balbuena, Christian Bartoluzzi, Emanuel Silva, Lorena Cabrera, Maria Curbelo, Javier Hryb, Jose Di Pace, Monica Perassolo, Sebastian Ianardi, Carolina Mainella, Surai Mellinger, Marcos Burgos, Diego Dias, Leonel Migliacci, Fátima Pagani Cassará, Vladimiro Sinay, Adriana Carra, Matias Questa Laudani, Emiliano Ruiz Romagnoli, Susana Liwacki, Raúl Piedrabuena, Santiago Tizio, Veronica Tkachuk, Edgar Carnero Contentti

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    • P1121 - Effector T cells are selectively controlled and related to postpartum relapses during pregnancy in MS (View Presentation)

      Keyword: Gender Differences, Hormones and Sex Chromosomes

      Steven Koetzier, Rinze Neuteboom, Annet Wierenga-Wolf, Marie José Melief, Ronald Van Der Wal, Angelique Van Rijswijk, Bieke Broux, Sjoerd Van Den Berg, Wim Dik, Joost Smolders, Marvin Van Luijn

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    • P1122 - Family planning in women with multiple sclerosis: an important yet seldom approached issue (View Presentation)

      Keyword: Reproductive Aspects and Pregnancy

      Ricardo Alonso, Cecilia Quarracino, Carlos Vrech, orlando Garcea, Berenice Silva, Norma Deri, Adriana Carrá, Anibal Chertcoff, Veronica Tkachuk, María Balbuena, Pablo Lopez, Edgar Carnero Contentti, Juan Pettinicchi, Darío Tavolini, Andres Barboza, Juan Rojas, Edgardo Cristiano, Liliana Patrucco, Luciana Lazaro, Nora Fernandez Liguori

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    • P1123 - Gender dimorphism of hippocampal intrinsic networks and regional integrity in multiple sclerosis (View Presentation)

      Keyword: Gender Differences, Hormones and Sex Chromosomes

      Dumitru Ciolac, Gabriel Gonzalez-Escamilla, Vinzenz Fleischer, Angela Radetz, Julia Krämer, Muthuraman Muthuraman, Sven Meuth, Sergiu Groppa

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    • P1124 - Health resource utilization in relapsing remitting multiple sclerosis from a gender perspective - evidence from more than 2000 patients in Germany (View Presentation)

      Keyword: Gender Differences, Hormones and Sex Chromosomes

      Dirk Schriefer, Nils Ness, Rocco Haase, Tjalf Ziemssen

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    • P1125 - Hypersexual Behavior and Multiple Sclerosis: A Systematic Review (View Presentation)

      Keyword: Reproductive Aspects and Pregnancy

      Francisco Aquino Gondim, David Lima Jr, Erick Maia Messias, Florian Thomas

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    • P1126 - Impact of interferon-beta exposure during early pregnancy on relapse rate (View Presentation)

      Keyword: Reproductive Aspects and Pregnancy

      Marianne Tokic, Sandra Thiel, Nastassja Litvin, Andrea Ciplea, Ralf Gold, Kerstin Hellwig

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    • P1127 - Menopause in multiple sclerosis (View Presentation)

      Keyword: Gender Differences, Hormones and Sex Chromosomes

      Celia Oreja-Guevara, Sandra Lopez-Coello, R Rodriguez-Rabanal, Irene Gómez_estévez, Judit Díaz-Díaz

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    • P1128 - MOG antibody disease and pregnancy (View Presentation)

      Keyword: Reproductive Aspects and Pregnancy

      María Ysrraelit, Susana Ochoa, Mauricio Farez, Jorge Correale

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    • P1129 - Peripartum depression and anxiety in women with MS. A population-based cohort study. (View Presentation)

      Keyword: Reproductive Aspects and Pregnancy

      Karine Eid, Øivind Torkildsen, Jan Aarseth, Heidi Flemmen, Trygve Holmøy, Kathrine Lian, Åslaug Lorentzen, Kjell Morten Myhr, Trond Riise, Cecilia Simonsen, Cecilie Torkildsen, Stig Wergeland, Johannes Sverre Willumsen, Nina Øksendal, Nils-Erik Gilhus, Marte-Helene Bjørk

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    • P1130 - Post-partum radiological disease activity in women with multiple sclerosis (View Presentation)

      Keyword: Reproductive Aspects and Pregnancy

      Tomas Uher, Eva Havrdova, Karolina Vodehnalova, Jan Krasensky, Manuela Vaneckova, Dana Horakova

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    • P1131 - Pregnancy in a modern day multiple sclerosis cohort: Predictors of postpartum relapse and disability progression (View Presentation)

      Keyword: Reproductive Aspects and Pregnancy

      Vilija Jokubaitis, Wei Yeh, Putu Widyastuti, Jim Stankovich, Melissa Gresle, Eva Kubala Havrdová, Dana Horakova, Karolina Vodehnalova, Serkan Ozakbas, Sara Eichau Madueño, Pierre Duquette, Tomas Kalincik, Francesco Patti, Cavit Boz, Murat Terzi, Bassem Yamout, Jeannette Lechner-Scott, Patrizia Sola, Olga Skibina, Michael Barnett, Md, Marco Onofrj, Maria José Sá, Pamela McCombe, Pierre Grammond, Radek Ampapa, Francois Grand'Maison, Roberto Bergamaschi, Daniele Spitaleri, Vincent Van Pesch, Elisabetta Cartechini, Suzanne Hodgkinson, Aysun Soysal, Albert Saiz, Tomas Uher, Davide Maimone, Recai Turkoglu, Raymond Hupperts, Maria Pia Amato, Franco Granella, Celia Oreja-Guevara, Ayse Altintas, Richard Macdonell, Tamara Castillo-Trivino, Helmut Butzkueven, Raed Alroughani, Anneke Van Der Walt, The Msbase Study Group

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    • P1132 - Pregnancy outcomes in patients treated with ocrelizumab (View Presentation)

      Keyword: Reproductive Aspects and Pregnancy

      Kiran Tailor, Riley Bove, Celia Oreja-Guevara, Kerstin Hellwig, Regine Buffels, Noemi Pasquarelli, Dusanka Zecevic, Sandra Vukusic

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    • P1133 - Pregnancy outcomes in the ozanimod multiple sclerosis clinical development program (View Presentation)

      Keyword: Reproductive Aspects and Pregnancy

      Johanna Moore, Neil Minton, Alyssa Henry, Anne Janjua, Gandhi Reddy Poli

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    • P1134 - Recovery of menstrual cycle in women with multiple sclerosis treated with autologous haematopoietic stem cell transplantation. (View Presentation)

      Keyword: Reproductive Aspects and Pregnancy

      Elvira Sbragia, Giacomo Boffa, Claudia Massarotti, Annamaria Raiola, Riccardo Varaldo, Emanuele Angelucci, Jessica Frau, Giovanni Bosco Zimatore, Giovanni Luigi Mancardi, Paola Anserini, Matilde Inglese

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    • P1135 - Risk factors for peripartum depression in women with multiple sclerosis (View Presentation)

      Keyword: Reproductive Aspects and Pregnancy

      Kristen Krysko, Annika Anderson, Jessica Singh, Kira McPolin, Alice Rutatangwa, William Rowles, A. Dessa Sadovnick, Maria Houtchens, Riley Bove

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    • P1136 - Severe neuroinflammatory relapse after ectopic pregnancy termination: a case report on MS patient with myelin oligodendrocyte glycoproteinantibodies. (View Presentation)

      Keyword: Reproductive Aspects and Pregnancy

      Helene Blad, Katja Kulmala, Roosa Vaitiniemi, Virginija Danylaite Karrenbauer

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    • P1137 - Sexual dysfunction in women  with relapsing remitting multiple sclerosis  in west Algeria (View Presentation)

      Keyword: Gender Differences, Hormones and Sex Chromosomes

      zahira Barka Bedrane , Djaoued Bouchenak Khelladi

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    • P1138 - short-chain fatty acid during pregnancy in multiple sclerosis: a prospective cohort study (View Presentation)

      Keyword: Reproductive Aspects and Pregnancy

      Juan Pablo Cuello, Roberto Alvarez-Lafuente, María L Martínez-Ginés, Amalia Tejeda-Velarde, Silvia Medina Heras, Jose Manuel García-Domínguez, Jose Ignacio Fernandez-Velasco, Alberto Lozano-Ros, Yolanda Higueras, Ariana Meldaña-Rivera, santiago Garcia Tizon, juan De-Leon Ruiz, Virginia Ortega Abad, Silvia Pérez-Pérez, María Inmaculada Domínguez-Mozo, Haydee Goicoechea-Briceño, Luisa María Villar

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    • P1139 - Silent MRI progression in MS patients during clinically stable pregnancy and post-partum period (View Presentation)

      Keyword: Reproductive Aspects and Pregnancy

      Iwona Rosciszewska-Zukowska, Malgorzata Siger, Mariusz Stasiołek

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    • P1140 - Study of anthropometric measures of newborns of MS mothers (View Presentation)

      Keyword: Reproductive Aspects and Pregnancy

      Judit Díaz-Díaz, Paola López-Gómez, Irene Gómez_estévez, Celia Oreja-Guevara

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    • P1141 - The 2D:4D ratio, a proxy for prenatal androgen levels, does not differ between Multiple Sclerosis patients and people without Multiple Sclerosis (View Presentation)

      Keyword: Gender Differences, Hormones and Sex Chromosomes

      Antonio Sánchez Soblechero, Sonia Castro Valdeolmillos, Judit Villamor Rodríguez, Jose Manuel García-Domínguez, María L Martínez-Ginés

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    • P1142 - “The contribution of sex hormones to disease incidence and phenotype in the spontaneous TCR1640 mouse model.” (View Presentation)

      Keyword: Gender Differences, Hormones and Sex Chromosomes

      Rose-Marie Rébillard, Margaux Mercier, Sandra Larouche, Olivier Tastet, Camille Grasmuck, Chloé Hoornaert, Lyne Bourbonniere, Alexandre Prat

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    • P1143 - The relationship between multiple sclerosis attacks and menstrual cycle days (View Presentation)

      Keyword: Gender Differences, Hormones and Sex Chromosomes

      Maryam Poursadeghfard, Saba Safavi

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    • P1144 - Comparison of deep grey matter iron deposition assessed by 3T MRI R2* relaxometry in Multiple Sclerosis, Alzheimer´s disease and in normal controls (View Presentation)

      Keyword: Imaging

      Isabella Colonna, Arabella Buchmann, Anna Damulina, Daniela Pinter, Birgit Helmlinger, Lukas Pirpamer, Martin Soellradl, Christian Tinauer, Stefan Ropele, Christian Enzinger, Reinhold Schmidt, Michael Khalil

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  • LBP01 - Late Breaking Posters

    • Type: LB Poster
    • Presentations: 132
    Presented on: 9/26/2020, 08:00
    View Posters

    • P0293 - Attenuation of antibody response to SARS-CoV-2 in a patient on ocrelizumab. (View Presentation)

      Keyword: COVID-19

      William Conte

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    • LB1144 - How does Coronavirus Disease 2019 (COVID-19) “Sheltering in Place” Affect Ambulatory Activity in People with Multiple Sclerosis? (View Presentation)

      Keyword: Biosensors

      Valerie Block, Riley Bove, Jeffrey Gelfand, Bruce Cree

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    • LB1145 - The 2020 COVID-19 pandemic and multiple sclerosis: Health behavior and lifestyle impacts in >1,000 people with MS  (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Andre Vogel, Hollie Schmidt, Sara Loud, Robert McBurney, Farrah Mateen

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    • LB1146 - Covid19 on U.S. and Canadian Neurologists’ Therapeutic Approach to Multiple Sclerosis: A Survey of Knowledge, Attitudes, and Practices (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Andre Vogel, Shawheen Rezai, Nicholas Alakel, Brittany Gazdag, Aditya Kumar, Farrah Mateen

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    • LB1147 - Multivitamin, Vitamin C and Vitamin D Pills Self-Medication in Multiple Sclerosis Patients in Montenegro During COVID-19 Pandemic (View Presentation)

      Keyword: Epidemiology

      Milovan Roganovic, Ljiljana Radulovic, Jevto Erakovic

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    • LB1148 - Neuromyelitis optica (NMO) practice and prescribing changes in the setting of Covid19: A survey of neurologists (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Shawheen Rezaei, Andre Vogel, Brittany Gazdag, Nicholas Alakel, Aditya Kumar, Farrah Mateen

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    • LB1149 - Perceptions of risk and adherence to care in MS patients during the COVID-19 pandemic: a cross-sectional study (View Presentation)

      Keyword: Observational Studies

      Yinan Zhang, Erin Staker, Gary Cutter, Stephen Krieger, Aaron Miller

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    • LB1150 - Multiple sclerosis during COVID-19 pandemic  in Santiago, Chile (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Carlos Guevara, Eduardo Villa, Marcela Cifuentes, Melissa Martinez, Cristian Garrido, Violeta Diaz, Carlos Silva-Rosas, Rodrigo Naves, Jose De Grazia

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    • LB1151 - Clinical outcomes in patients with COVID-19 infection during phase IV studies of cladribine tablets for treatment of multiple sclerosis (View Presentation)

      Keyword: Clinical Trials

      Esther Dodge, Radmila Karan, Sanjeev Roy, Nektaria Alexandri

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    • LB1152 - COVID-19 and lockdown in patients with multiple sclerosis: a descriptive study of prevalence and emotional impact (View Presentation)

      Keyword: Observational Studies

      Yolanda Higueras, Ariana Meldaña-Rivera, Jose Manuel García-Domínguez, Haydee Goicochea Briceño, Juan Pablo Cuello, Alberto Lozano-Ros, María L Martínez-Ginés

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    • LB1154 - COVID-19 in cladribine-treated patients with relapsing-remitting multiple sclerosis: a monocentric experience (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Paolo Preziosa, Maria A. Rocca, Agostino Nozzolillo, Lucia Moiola, Massimo Filippi

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    • LB1155 - Vitamin D levels in the UK MS population and COVID-19 susceptibility (View Presentation)

      Keyword: Epidemiology

      Nikki Vickaryous, Afagh Garjani, Ben Jacobs, Mark Jitlal, Rod Middleton, Roshan Das Nair, Katie Tuite-Dalton, Rachael Hunter, Siddharthan Chandran, Niall Macdougall, Richard Nicholas, Gavin Giovannoni, Nikos Evangelou, Ruth Dobson

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    • LB1156 - Physical activity behavior in people with multiple sclerosis during the COVID-19 pandemic in Israel: Results of an online survey (View Presentation)

      Keyword: Rehabilitation and Comprehensive Care

      Alon Kalron, Michal Greenberg-Abrahami, Shay Menascu, Roy Aloni, Lior Frid, Mark Dolev, David Magalashvili, Anat Achiron

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    • LB1157 - Experiences of Latin American MS and/or NMOSD experts in practice during the COVID-19 pandemic: focus in Telemedicine. (View Presentation)

      Keyword: Internet and Social Media

      Ricardo Alonso, René Carvajal, Mateus Boaventura, Lorna Galleguillos

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    • LB1158 - COVID-19 pandemic and mental distress in Multiple Sclerosis: implications for clinical management (View Presentation)

      Keyword: Neuropsychology and Cognition

      Teresa Costabile, Antonio Carotenuto, Luigi Lavorgna, Giovanna Borriello, Lucia Moiola, Matilde Inglese, Martina Petruzzo, Francesca Trojsi, Antonio Ianniello, Agostino Nozzolillo, Maria Cellerino, Giacomo Boffa, Laura Rosa, Giuseppe Servillo, Marcello Moccia, Simona Bonavita, Massimo Filippi, Roberta Lanzillo, Vincenzo Brescia Morra, Maria Petracca

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    • LB1159 - The Effect of COVID-19 Pandemic on Treatment Adherence of People with Multiple Sclerosis (View Presentation)

      Keyword: Clinical Outcome Measures

      Fatih Mehmet Yetkin, Merve Akcakoyunlu, Meral Mirza

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    • LB1160 - Multiple Sclerosis patients and Health Care accessibility during COVID-19 Pandemic (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Mafalda Seabra, Andreia Costa, Daniela Ferro, Maria Pinto, Bárbara Martins, Teresa Mendonça, Joana Guimarães, Pedro Abreu, Ricardo Reis, Maria José Sá

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    • LB1161 - Teleneurology for MS care at two large academic centers before and during the-COVID-19 pandemic (View Presentation)

      Keyword: Internet and Social Media

      Marisa McGinley, Shauna Gales, Zhini Wang, Wan-Yu Hsu, William Rowles, Riley Bove

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    • LB1162 - Rapid transfer of knowledge for multiple sclerosis clinical care during COVID-19: ECHO MS (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Kevin Alschuler, Gloria Von Geldern, Darren Ball, Kathleen Costello, Mark Skeen, Salim Chahin, Annette Wundes

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    • LB1164 - "Awareness of Covid-19 in patients with MS in Saudi Arabia" (View Presentation)

      Keyword: Epidemiology

      Razan Jabbad, hind Alnajashi

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    • LB1165 - COVID-19 in cladribine-treated patients with Multiple Sclerosis (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Celia Oreja-Guevara, Virginia Meca-Lallana, LUIS Brieva, Eva Fernandez-Diaz, Jose Manuel García-Domínguez, Daniel Garcia-Estevez, Gloria Llorens, Irene Moreno-Torres, Francisco José Valenzuela

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    • LB1166 - Risk and outcomes of COVID-19 in patients with multiple sclerosis in Madrid Spain  (View Presentation)

      Keyword: Epidemiology

      Irene Moreno-Torres, Virginia Meca-Lallana, Lucienne Costa-Frossard, Celia Oreja-Guevara, Clara Aguirre, Elda Alba Suárez, Mayra Gómez Moreno, Laura Borrega Canelo, Julia Sabín-Muñoz, Yolanda Aladro, Alba Cárcamo Fonfría, Elena Rodríguez García, Juan Pablo Cuello, Enric Monreal, Susana Sainz de la Maza, Fernando Perez Parra, Francisco José Valenzuela, Carlos Lopez De Silanes, Luis Ignacio Casanova Peño, María L Martínez-Ginés, María Rosario Blasco Quílez, Aida Orviz García, Luisa María Villar, Carmen Santiuste, Mercedes Espiño, Guillermo Fernandez-Dono, Victor Elvira

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    • LB1167 - Reported Covid19 symptoms in patients on oral Disease Modifying Treatmentss (DMTs) at a single centre (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Rachel Dorsey-Campbell, Chandni Radia, anushka Dewan, Rina Gokani, Teresa Felongco, Dionisio Delacruz, Ashwini Nandoskar, Victoria Singh-Curry, Antonio Scalfari, Omar Malik, Richard Nicholas

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    • LB1168 - COVID-19 in MS patients: susceptibility and severity risk factors (View Presentation)

      Keyword: Prognostic Factors

      Ana Zabalza, Paula Tagliani, Simón Cárdenas-Robledo, Georgina Arrambide, Susana Otero-Romero, Pere Carbonell-Mirabent, Marta Rodríguez, Breogán Rodríguez-Acevedo, Juan Luís Restrepo-Vera, Mireia Resina-Sallés, Luciana Midaglia, Anka Vidal-Jordana, Jordi Río, Íngrid Galán, Joaquín Castilló, Alvaro Cobo Calvo, Manuel Comabella, Carlos Nos, Jaume Sastre-Garriga, Mar Tintore, Xavier Montalban

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    • LB1169 - Psychological consequences of COVID-19 pandemic in Italian MS patients: a surprising resilience  (View Presentation)

      Keyword: Neuropsychology and Cognition

      Manuela Altieri, Rocco Capuano, Alvino Bisecco, Alessandro D'Ambrosio, Renato Docimo, Daniela Buonanno, Federica Matrone, Federica Giuliano, Gioacchino Tedeschi, Gabriella Santangelo, Antonio Gallo

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    • LB1170 - Use of IVIG in three immunosuppressed patients hospitalized with COVID-19 (View Presentation)

      Keyword: COVID-19

      Edith Graham, Jonathan Datar, Carolyn Bevan, Elena Grebenciucova, Igor Koralnik, Bruce Cohen, Roumen Balabanov

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    • LB1171 - Embracing resilience in Multiple Sclerosis: a new perspective from COVID-19 pandemic. (View Presentation)

      Keyword: Neuropsychology and Cognition

      Elvira Sbragia, eleonora Colombo, Chiara Pollio, Maria Cellerino, caterina Lapucci, Matilde Inglese, Giovanni Luigi Mancardi, Giacomo Boffa

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    • LB1172 - MS and COVID-19: A Webinar Series for Healthcare Providers (View Presentation)

      Keyword: Internet and Social Media

      Doris Lill, Kathleen Costello, Julie Fiol, June Halper

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    • LB1174 - Patient and healthcare professional perspectives of immune dynamics and MS disease-modifying therapies mode of action throughout COVID-19 pandemic   (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Holly Hunter, Jeri Burtchell, Daisy Clemmons, Joann Clemmons, Jennifer Graves, Michael Sweeney, John Kramer, Marina Ziehn, Brandon Brown, Jamie Weiss, Ahmed Obeidat

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    • LB1175 - Multiple Sclerosis patients and disease management during COVID-19 Pandemics (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Daniela Ferro, Andreia Costa, Ricardo Soares-Dos-Reis, Mafalda Seabra, Maria Pinto, Bárbara Martins, Cláudia Sousa, Teresa Mendonça, Joana Guimarães, Pedro Abreu, Maria José Sá

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    • LB1176 - Anxiety affects the general well-being of people with MS during the COVID-19 pandemic more than the infection itself (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Afagh Garjani, Rachael Hunter, Richard Nicholas, Rod Middleton, Katie Tuite-Dalton, Alasdair Coles, Ruth Dobson, Martin Duddy, David Ford, Stella Hughes, Owen Pearson, David Rog, Emma Tallantyre, Graham Law, Roshan Das Nair, Nikos Evangelou

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    • LB1177 - PAMRINO: International MRI and clinical data repository for neuromyelitis optica spectrum disorder (View Presentation)

      Keyword: Imaging

      Claudia Chien, Hanna Zimmermann, Svenja Specovius, Frederike Cosima Oertel, Denis Bichuetti, Marcos Idagawa, Ayse Altintas, Uygur Tanriverdi, Sasitorn Siritho, Lekha Pandit, Anitha D'Cunha, Maria José Sá, Rita Figueiredo, Caryl Tongco, Peiqing Qian, Itay Lotan, Vadim Khasminsky, Mark Hellmann, Hadas Stiebel-Kalish, Dalia Rotstein, Lindsay Waxman, Daniel Ontaneda, Kunio Nakamura, Hesham Abboud, Mhd Omar Subei, Yang Mao-Draayer, Joachim Havla, Nasrin Asgari, Ilya Kister, Zoe Rimler, Allyson Reid, Marius Ringelstein, S Broadley, Simon Arnett, Brie Marron, Anna Jolley, Michael Wunderlich, Sean Green, Lawrence Cook, Michael Yeaman, Terry Smith, Alexander Brandt, Pernille Skejø, Vera Cruz Silva, Jens Wuerfel, Friedemann Paul, GJCF International Clinical Consortium For Nmosd

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    • LB1178 - Monitoring of blood neurofilaments improves stratification of disease activity in multiple sclerosis (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Tomas Uher, Eva Havrdova, Pascal Benkert, Niels Bergsland, Jan Krasensky, Barbora Srpová, Michael Dwyer, Michaela Tyblova, Manuela Vaneckova, Dana Horakova, Robert Zivadinov, David Leppert, Tomas Kalincik, Jens Kuhle

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    • LB1179 - Predictors of Disease Modifying Treatment Failure Amongst Neuromyelitis Optica Spectrum Disorder Patients, Stratified by Antibody Serostatus (View Presentation)

      Keyword: Prognostic Factors

      Kelly Polito, Talat Islam, Lilyana Amezcua, Margaret Burnett, Vivek Patel

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    • LB1181 - COVID-19 Outcomes among patients with Multiple Sclerosis: Experience from RWJBH Multiple Sclerosis Comprehensive Care Center (View Presentation)

      Keyword: COVID-19

      Matthew Tremblay, Carissa Greco, Viktoriya Busko, Elisabeth Dealca, Phoebe Del Boccio, Andrew Sylvester

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    • LB1182 - Multiple Sclerosis and the psychological impact of COVID-19  (View Presentation)

      Keyword: COVID-19

      Hannah Morris-Bankole, Aileen Ho

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    • LB1183 - Utilizing Optical Coherence Tomography to Assess the Gender Role on Retinal Structures in Patients with Early MS (View Presentation)

      Keyword: Neuro-Ophthalmology

      Melody Hackett, Madeline Bross, Carla Santiago-Martinez, Evanthia Bernitsas

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    • LB1184 - Molecular models of multiple sclerosis severity identify heterogeneity of pathogenic mechanisms (View Presentation)

      Keyword: Machine Learning/Network Science

      Christopher Barbour, Peter Kosa, Mihael Varosanec, Mark Greenwood, Bibiana Bielekova

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    • LB1185 - Real-world experience with Ocrelizumab in the German NeuroTransData Registry (View Presentation)

      Keyword: Observational Studies

      Stefan Braune, Yanic Heer, Viola Tozzi, Philip Van Hoevell, Erwan Muros-Le Rouzic, Petra Dirks, Arnfin Bergmann

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    • LB1186 - Investigating fractalkine as a potential remyelination therapy in the cuprizone MS mouse model (View Presentation)

      Keyword: Neuroprotection, Regeneration and/or Remyelination

      Monique Marylin Alves De Almeida, Adrianne Watson, Fajar Khan, Jessica Li, Kara Goodkey, Tim Footz, Danny Galleguillos, Simonetta Sipione, Anastassia Voronova

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    • LB1187 - Evaluation of multiple sclerosis progression with clinic parameters in Tomsk Region, Russian Federation (View Presentation)

      Keyword: Prognostic Factors

      Ekaterina Kamenskih, Valentina Alifirova, Ekaterina Koroleva, Daria Pashkovskaya, Natalya Brazovskaya

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    • LB1188 - Epidemiology of COVID-19 among persons with neuroimmunological disorders at the Columbia University MS Center in New York City (View Presentation)

      Keyword: COVID-19

      Kathryn Fong, Samantha Epstein, Kiran Thakur, Amelia Boehme, Phillip De Jager, Libby Levine, Wendy Vargas, Claire Riley, Rebecca Straus Farber

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    • LB1189 - Diagnostic Value of  DWI-MRI for Detecting Acute Plaqes in  Relapse Phase of  Multiple Sclerosis (View Presentation)

      Keyword: Imaging

      Mehdi Maghbooli, Mehran Yousefi, Mehdi Panahali

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    • LB1190 - The Emotional Impact of the COVID-19 Pandemic on Individuals with Progressive Multiple Sclerosis. (View Presentation)

      Keyword: COVID-19

      Nancy Chiaravalloti, Maria Pia Amato, Giampaolo Brichetto, Jeremy Chataway, Ulrik Dalgas, John Deluca, Cecilia Meza, Nancy Moore, Peter Feys, Massimo Filippi, Jennifer Freeman, matilde Inglese, Robert Motl, Maria A. Rocca, Brian Sandroff, Amber Salter, Gary Cutter, Anthony Feinstein

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    • LB1191 - Validation of the Italian version of the Multiple sclerosis intimacy and sexuality questionnaire-19 (View Presentation)

      Keyword: Patient-Reported Outcomes and Quality of Life

      Antonio Carotenuto, Laura De Giglio, Alessandro Chiodi, Maria Petracca, Laura Rosa, Maurizio Bianchi, Ilaria Ferrante, Francesca Lauro, Marcello Moccia, Antonio Ianniello, Carlo Pozzilli, Vincenzo Brescia Morra, Roberta Lanzillo

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    • LB1193 - The Framingham cardiovascular risk score and 5-year progression of multiple sclerosis (View Presentation)

      Keyword: Comorbidities

      Antonio Reia, Martina Petruzzo, Giorgia Teresa Maniscalco, Fabrizio Luiso, Roberta Lanzillo, Cinzia Russo, Antonio Carotenuto, Lia Allegorico, Raffaele Palladino, Vincenzo Brescia Morra, Marcello Moccia

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    • LB1194 - Analysis of count data in MS clinical trials (View Presentation)

      Keyword: Biostatistical Methods

      Brian Healy

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    • LB1195 - Changes in Mobility and Brain Connectivity following over-ground Robotic Exoskeleton Rehabilitation in Persons with MS (View Presentation)

      Keyword: Rehabilitation and Comprehensive Care

      Peter Niewrzol, Glenn Wylie, Guang Yue, John Deluca, Ghaith Androwis

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    • LB1196 - Enhancing myelin repair in MS preclinical models by modulating the cholesterol biosynthesis pathway (View Presentation)

      Keyword: Neuroprotection, Regeneration and/or Remyelination

      Carlos Pedraza, Guoqing Sheng, Kristin Radzwill, Lilu Guo, Carrie Garron, Stephanie Holley, Kristen Randall, Tatiana Gladysheva, Gregory Merrriman

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    • LB1197 - Myelin water imaging provides evidence for unique anatomical-functional relationships between myelin damage and different cognitive domains in MS (View Presentation)

      Keyword: Imaging

      Shawna Abel, Adam Dvorak, Sarah Morris, Irene Vavasour, Poljanka Johnson, Stephen Ristow, Lisa Eunyoung Lee, Jillian Chan, Cornelia Laule, Alice Schabas, Helen Cross, Roger Tam, Annie Kuan, Sarah Morrow, Jeffrey Wilken, Ana Luiza Sayao, Virginia Devonshire, David Li, Robert Carruthers, Anthony Traboulsee, Shannon Kolind

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    • LB1199 - Marked increase of CSF sampling induced vasovagal response secondary to COVID-19 pandemic (View Presentation)

      Keyword: COVID-19

      alexis Gagnon

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    • LB1200 - The SUNLIGHT Study: A telehealth intervention to address mental health in persons with MS during COVID-19  (View Presentation)

      Keyword: Clinical Trials

      Victoria Leavitt, Anne Kever, Ines Aguerre, Claire Riley, Phillip De Jager, Kathryn Fong, Libby Levine, Rebecca Straus Farber, Wendy Vargas, Minnelly Vasquez

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    • LB1201 - SARS-CoV-2 associated Neuromyelitis optica (View Presentation)

      Keyword: COVID-19

      Tzu-Ying Chuang, Dhanashri Miskin

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    • LB1202 - The effects of obesity on retinal structures in African American and Caucasian relapsing remitting multiple sclerosis patients (View Presentation)

      Keyword: Imaging

      Madeline Bross, Melody Hackett, Ellyse Probst-Simmons, Rachel Darling, Carla Santiago-Martinez, Jacob Rube, Evanthia Bernitsas

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    • LB1203 - Neuromyelitis optica spectrum disorders (NMOSD) attack triggered by COVID-19 infection (A case report) (View Presentation)

      Keyword: COVID-19

      Ahmed Nasreldein, Hamdy Ibrahem, Ahmad Bahie

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    • LB1205 - Covid-19 Infection in Patients with Multiple Sclerosis: an observational study by The New York COVID-19 Neuro-Immunology Consortium (NYCNIC) (View Presentation)

      Keyword: COVID-19

      Sylvia Klineova, Asaff Harel, Rebecca Straus Farber, Yinan Zhang, Tracy Deangelis, Tung Ming Leung, Kathryn Fong, Tyler Smith, Richard Blanck, Susan Filomena, Martha Karran, Stella Gurgova, Kaho Onomichi, Lana Zhovtis-Ryerson

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    • LB1206 - Sars-Cov-2 infection releated inflammatory and demyelinating disease; a brief case series (View Presentation)

      Keyword: COVID-19

      nurhan Kaya Tutar, sami Omerhoca, eda Coban, nilufer Kale

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    • LB1207 - Elevated levels of serum CD5 antigen-like protein distinguish secondary progressive multiple sclerosis from other disease subtypes (View Presentation)

      Keyword: Pathogenesis – Immunology

      Emily Kamma, Pierre Becquart, Robert Carruthers, Anthony Traboulsee, Irene Vavasour, Cornelia Laule, Jacqueline Quandt

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    • LB1208 - Linking structural and functional brain alterations in relapsing-remitting MS (View Presentation)

      Keyword: Imaging

      Jian Zhang, Antonio Giorgio, Claudia Vinciguerra, Maria Laura Stromillo, Marzia Mortilla, Riccardo Tappa Brocci, Marco Battaglini, Emilio Portaccio, Maria Pia Amato, Nicola De Stefano

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    • LB1209 - A tablet-based videogame for capturing slowing processing speed in multiple sclerosis patients: a pilot study (View Presentation)

      Keyword: Neuropsychology and Cognition

      Marco Pitteri, Caterina Dapor, Stefano Ziccardi, Maddalena Guandalini, Riccardo Meggiato, Massimiliano Calabrese

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    • LB1210 - Cerebrospinal fluid inflammatory profile of cognitive dysfunction in newly diagnosed multiple sclerosis patients (View Presentation)

      Keyword: Neuropsychology and Cognition

      Marco Pitteri, Roberta Magliozzi, Stefano Ziccardi, Anna Pisani, Massimiliano Calabrese

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    • LB1211 - Histaminergic basis of fatigue in Multiple Sclerosis (View Presentation)

      Keyword: Clinical Trials

      Kottil Rammohan, Neeta Garg, Leticia Tornes, Chao Zheng, Sanjoy Bhattacharya

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    • LB1212 - Evaluating Multiple Sclerosis patients for gluten sensitivity – worthwhile or not? (View Presentation)

      Keyword: Comorbidities

      Sasini Bentota, Elizabeth Crabtree

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    • LB1213 - Attention-based deep learning identifies a new microstructural diffusion MRI contrast sensitive to focal pathology and related to patient disability (View Presentation)

      Keyword: Machine Learning/Network Science

      Po-Jui Lu, Muhamed Barakovic, Matthias Weigel, Reza Rahmanzadeh, Riccardo Galbusera, Simona Schiavi, Alessandro Daducci, Jens Kuhle, Ludwig Kappos, Philippe Cattin, Cristina Granziera

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    • LB1214 -  Antiviral activity of Interferon beta-1b to SARS-CoV-2 infection (View Presentation)

      Keyword: COVID-19

      Felisa Leguizamón, Francisco Knorre

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    • LB1215 - "Clinical course, Safety of Low-dose Rituximab for Vietnameses Patients with Neuromyelitis Optica Spectrum Disorder" (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Thuy Le

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    • LB1216 - Cortical and deep grey matter volume loss is specifically linked to cerebrospinal fluid inflammation in early multiple sclerosis. (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Albulena Bajrami, Roberta Magliozzi, Anna Pisani, Francesco Crescenzo, Damiano Marastoni, Massimiliano Calabrese

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    • LB1217 - Macular pigment concentration and distribution in multiple sclerosis (View Presentation)

      Keyword: Neuro-Ophthalmology

      Grigorios Kalaitzidis, Angeliki Filippatou, Olwen Murphy, Jeffrey Lambe, Eleni Vasileiou, Henrik Ehrhardt, Nicole Pellegrini, Elias Sotirchos, Peter Calabresi, Kathryn Fitzgerald, Shiv Saidha

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    • LB1218 - Impact of COVID-19 on MS patients’ access to care and neurologists’ treatment practices worldwide: results from the ECTRIMS survey (View Presentation)

      Keyword: COVID-19

      Emilio Portaccio, Mattia Fonderico, Bernhard Hemmer, Tobias Derfuss, Bruno Stankoff, Krzysztof Selmaj, Mar Tintore, Maria Pia Amato

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    • LB1219 - Normal serum NFL levels: a proposal of cut-off strategy definition for the clinical practice (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      paola Valentino, Fabiana Marnetto, Serena Martire, Cecilia Bava, Maja Popovic, Antonio Bertolotto

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    • LB1220 - Real-life experience with sNFL in Multiple Sclerosis patients, as monitoring and treatment decision biomarker   (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      paola Valentino, Fabiana Marnetto, Cecilia Bava, Serena Martire, Antonio Bertolotto

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    • LB1221 - Applicability of sNFL in Multiple Sclerosis as additional measure in clinical practice and implications in NEDA-3 evaluation.   (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Antonio Bertolotto, Simona Malucchi, Fabiana Marnetto, Serena Martire, paola Valentino

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    • LB1222 - Outcomes of coronavirus disease 2019 in patients with neuromyelitis optica and associated disorders (View Presentation)

      Keyword: COVID-19

      Celine Louapre, Elisabeth Maillart, Caroline Papeix, Sinead Zeidan, Damien Biotti, Zoe Lepine, Abir Wahab, Mickael Zedet, Pierre Labauge, Caroline Tilikete, Julie Pique, Ayman Tourbah, Guillaume Mathey, Dalia Dimitri Boulos, Pierre Branger, Laurent Kremer, Romain Marignier, Nicolas Collongues, Jerome De Seze

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    • LB1223 - Telehealth: another tool in the toolkit to provide usual care to people with Multiple Sclerosis during the COVID-19 pandemic. (View Presentation)

      Keyword: COVID-19

      Anne Parkinson, Janet Drew, Sally Hall, Katrina Chisholm, Mark Elisha, Vanessa Fanning, Christine Phillips, Christian Lueck, Jane Desborough

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    • LB1224 - Thalamic and whole brain atrophy are linked with white matter microglial activation: A [F-18]PBR06-PET study in multiple sclerosis  (View Presentation)

      Keyword: Pathogenesis – Role of Glia

      Kelsey Carter, Steven Cicero, Renxin Chu, Shipra Dubey, Shahamat Tauhid, Eero Rissanen, Hong Pan, Mi-ae Park, Marie Kijewski, Emily Stern, David Silbersweig, Rohit Bakshi, Howard Weiner, Tarun Singhal

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    • LB1225 - Acute disseminated encephalomyelitis in a pediatric patient in the setting of SARS-CoV2 with histopathology (View Presentation)

      Keyword: COVID-19

      Jocelyn Lorenzo, Natalia Gonzalez Caldito, Cynthia Wang

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    • LB1226 - Use and safety of interferon beta-1b during the COVID-19 outbreak: current data from a pharmacovigilance safety database (View Presentation)

      Keyword: COVID-19

      Beth Gates, Anthony Reder, Alessandra Adamo, Eva-Maria Wicklein, Aasia Bhatti

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    • LB1227 - Glatiramer Acetate Depot (extended-release) phase IIa study in patients with Primary Progressive Multiple Sclerosis: safety and efficacy snapshot (View Presentation)

      Keyword: Clinical Trials

      Shlomo Flechter, Laura Popper, Nadav Bleich Kimelman, Inna Demender, Shai Rubnov, Uri Danon, Ehud Marom, Ron Milo, Ronit Gilad, Boaz Weller, Adi Vaknin-Dembinsky, Mark Hellmann, Arnon Karni

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    • LB1228 - Glatiramer Acetate Depot (Extended-Release) Phase IIa Study in Patients with RRMS: Safety, Tolerability and Efficacy Four-Years Analysis (View Presentation)

      Keyword: Clinical Trials

      Shlomo Flechter, Ariel Miller, Laura Popper, Nadav Bleich Kimelman, Shai Rubnov, Uri Danon, Ehud Marom, Ron Milo, Joab Chapman, Alla Shifrin, Ronit Gilad, Chen Hoffmann, Dimitrios Karussis, Arnon Karni

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    • LB1229 - CLASSIC-MS: Long-term efficacy and real-world treatment patterns for patients receiving cladribine tablets - interim data with 8–14 years follow-up (View Presentation)

      Keyword: Clinical Trials

      Esther Dodge, Gavin Giovannoni, Thomas Leist, Aida Aydemir, Elisabetta Verdun Di Cantogno

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    • LB1230 - Longitudinally Extensive Transverse Myelitis in association with COVID-19 (View Presentation)

      Keyword: COVID-19

      shaista Siddiqi, Jai Perkash, Mona Thakre, jihad Inshasi, abubaker Almadani, Yasir Malik, Raheel Ahmed, yasmine Mohamed

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    • LB1231 - Demographic and Clinical Profile of Pediatric patients with Multiple Sclerosis infected with SARS-Cov2 (View Presentation)

      Keyword: COVID-19

      Teri Schreiner, Tanuja Chitnis, Jan-Mandelt Tillema, Leslie Benson, Mark Gorman, Manu Goyal, Yolanda Harris, Lauren Krupp, Timothy Lotze, Soe Mar, Jayne Ness, Mary Rensel, Moses Rodriguez, Nikita Shukla, Emmanuelle Waubant, John Rose, Shelly Roalstad, T. Charles Casper

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    • LB1232 - Managing Multiple sclerosis patients diagnosed with COVID-19 infection; into the field of unknown (View Presentation)

      Keyword: COVID-19

      sami Omerhoca, Zerrin Yıldırım, Nurhan Kaya Tutar, nilufer Kale

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    • LB1233 - Blood brain barrier permeability and high dose corticosteroids for MS relapses: a pilot study (View Presentation)

      Keyword: Observational Studies

      Sarah Morrow, Jordan Ward, Heather Rosehart, Courtney Casserly, Anna Macdonald, Tony Wales, Ting-Yim Lee

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    • LB1234 - COVID-19 infections in NMOSD and MOGAD: a population based study (View Presentation)

      Keyword: COVID-19

      Marco Capobianco, Giancarlo Comi, Maria Pia Sormani, Francesco Patti

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    • LB1235 - Frequency of SARS-CoV-2 antibodies and COVID-19 severity in a cohort of Italian multiple sclerosis patients on DMTs inhibiting immune cell trafficking (View Presentation)

      Keyword: COVID-19

      Giulia Mallucci, Antonio Zito, Beatrice Dal Fabbro, Matteo Gastaldi, Diego Franciotta, Roberto Bergamaschi

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    • LB1236 - The role of ten eleven translocase 2 (TET2) in the regulation of autoimmune demyelinating disease (View Presentation)

      Keyword: Genetics and Epigenetics

      Ashley Munie, Benjamin Segal

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    • LB1237 - An Antigen-Specific Microparticle Formulation Therapeutically Treats a Mouse Model of Multiple Sclerosis (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Alexander Kwiatkowski, Joshua Stewart, Eric Helm, Theodore Drashansky, Ashley Zuniga, Dorina Avram, Benjamin Keselowsky

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    • LB1238 - Myelin Oligodendrocyte Glycoprotein-antibody positive transverse myelitis presenting as acute flaccid paralysis in a child with enterovirus infection (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Victor Salinas, Jocelyn Lorenzo, Cynthia Wang

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    • LB1239 - Pharmacodynamic modeling and exposure-response assessment of inebilizumab in subjects with neuromyelitis optica spectrum disorders (View Presentation)

      Keyword: Neuromyelitis Optica and Anti-MOG Disease

      Li Yan, Bing Wang, Dewei She, Ben Mitchel, Ryan Criste, Daniel Cimbora, Eliezer Katz, William Rees

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    • LB1240 - A kappa free light chain index of 6.6 represents an alternative to positive oligoclonal bands in the 2017 McDonald criteria (View Presentation)

      Keyword: Diagnostic Criteria and Differential Diagnosis

      Georgina Arrambide, Carmen Espejo, Romina Dieli, Cristina Auger, Mireia Castillo, Maria Rodriguez-Barranco, Pere Carbonell-Mirabent, Jordi Río, Joaquín Castilló, Anka Vidal-Jordana, Íngrid Galán, C Nos, Manuel Comabella, Breogán Rodríguez-Acevedo, Luciana Midaglia, Ana Zabalza, Alvaro Cobo Calvo, Paula Tagliani, Simón Cárdenas-Robledo, Jaume Sastre-Garriga, Alex Rovira, Manuel Hernández-González, Xavier Montalban, Mar Tintore

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    • LB1241 - Incidence and clinical outcome of COVID-19 in a cohort of 11.560 Brazilian patients with Multiple Sclerosis (View Presentation)

      Keyword: COVID-19

      Maria Fernanda Mendes, Maria Lúcia Ferreira, Nise Alessandra Sousa, Rodrigo Thomaz, Samira Luisa Apóstolos-Pereira, Soniza Alves-Leon, Ana Claudia Piccolo, Enedina Maria De Oliveira, Claudia Cristina Vasconcelos, André Muniz, Antonio Gomes Neto, Bianca Etelvina De Oliveira, Fernando Da Rocha, Gabriela Martins, Gutemberg Augusto Dos Santos, Heloisa Helena Ruocco, Herval Soares Neto, MARIA CECÍLIA De Vecino, Mateus Boaventura, Ronaldo Maciel Dias, Sidney Gomes, Andréa Castro, José Artur D'Almeida, Luciano Rocha, Maria Lúcia Pimentel, Milena Pitombeira, Omar Arambula, Valeria Pereira, Hideraldo Cabeça, Marcus Vinicius Gonçalves, Rafael Dias-Carneiro, Lis Ferreira, Raul Guimarães, Carlos Magno Fortaleza, Denise Diniz, Anderson Grzesiuk, Damacio Ramón Kaimen-Maciel, Elizabeth Comini-Frota, Guilherme Do Olival, Heloise Helena Siqueira, Henry Sato, Leandro Calia, Luiz Domingos Melges, Mario Emilio Dourado Junior, Marlise Ribeiro, Marlos Aureliano Sousa, Mônica Parolin, Paulo Da Gama, Rogério Morales, Silvana Sobreira, Suzana Machado, Taysa Ribeiro, Thiago Fukuda, Vanessa Costa, Vera Lúcia Vieira, Marilia Perin, Adaucto Da Nóbrega Junior, Alvaro José Moreira, Caio Cesar Disserol, Camila De Oliveira E Silva, Carlos Alberto Peixoto, Edmur Pugliesi, Helio Miot, Jose Alexandre Figueiredo Junior, Leizian Amorim, Letícia Scolari, Lucas Feo, Lucas Mendes, Maria Iris Machado, Rafael Catão, Renata Menon, Eduardo Donadi, Dagoberto Callegaro, Yara Fragoso, Tarso Adoni, Felipe Von Glehn, Doralina Brum

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    • LB1242 - COViMS Registry: Clinical Characterization of SARS-CoV-2 Infected Multiple Sclerosis Patients in North America (View Presentation)

      Keyword: COVID-19

      Amber Salter, June Halper, Bruce Bebo, Pamela Kanellis, Kathleen Costello, Gary Cutter, Scott Newsome, David Li, Robert Fox, Kottil Rammohan, Anne Cross

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    • LB1243 - Disease modifying treatment changes in pediatric onset multiple sclerosis patients over the past 10 years. A single center retrospective study. (View Presentation)

      Keyword: Pediatric MS

      Nicole Moore, Alfred Balasa, Kristen Fisher, Margaret Codispoti, Nikita Shukla, Timothy Lotze

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    • LB1244 - Manifestations and Impact of the COVID-19 Pandemic in Neuroinflammatory Diseases (View Presentation)

      Keyword: COVID-19

      Zongqi Xia, Seth Levin, Shruthi Venkatesh, Katie Nelson, Yi Li, Ines Aguerre, Wen Zhu, Karman Masown, Kathryn Fong, Claudiu Diaconu, Kaho Onomichi, Victoria Leavitt, Libby Levine, Rebecca Straus Farber, Wendy Vargas, Brenda Banwell, Christopher Perrone, Amit Bar-Or, Joseph Berger, Andrew Goodman, Erin Longbrake, Jiwon Oh, Bianca Weinstock-Guttman, Kiran Thakur, Keith Edwards, Claire Riley, Phillip De Jager

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    • LB1245 - BB-CRESM: a structured institutional biobank for quality research in Multiple Sclerosis. (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Fabiana Marnetto, paola Valentino, Marzia Caldano, Antonella Ficorilli, Alessandro Paudice, Antonio Bertolotto

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    • LB1246 - Future implementation of automated analysis tools for Multiple Sclerosis on conventional magnetic resonance imaging. (View Presentation)

      Keyword: Imaging

      Chloe Lim, Hayyan Liaqat, William Siu, Ghassan Hamarneh, George Medvedev

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    • LB1247 - Clinical features of COVID-19 in patients with neuromyelitis optica spectrum disorders  (View Presentation)

      Keyword: COVID-19

      Mateus Boaventura, Samira Apóstolos-Pereira, Lis Ferreira, Nise Sousa, Gabriela Martins, José Artur Costa D’almeida, Milena Pitombeira, Lucas Mendes, Thiago Fukuda, Luciano Rocha, Hideraldo Cabeça, Bianca Oliveira, Carla Vieira Stella, Enedina Maria Oliveira, Leizian Amorim, Andréa Castro, Antônio Pereira Gomes Neto, Guilherme Silva, Lucas Bueno, Maria Machado, Rafael Paternó Castello Dias-Carneiro, Ronaldo Dias, Alvaro Moreira, Ana Claudia Piccolo, Anderson Grzesiuk, André Muniz, Caio Disserol, Claudia Cristina Vasconcelos, Denise Diniz, Damacio l Kaimen-Maciel, Elizabeth Comini-Frota, Fernando Rocha, Guilherme Sciascia Do Olival, Gutemberg Augusto Santos, Heloisa Helena Ruocco, Heloise Helena Siqueira, Henry Sato, Herval Soares Neto, José Figueiredo Jr, Leandro Calia, Letícia Scolari, Luiz Domingos Melges, Marcus Vinícius Magno Gonçalves, Maria Lúcia Pimentel, Mario Emilio Dourado Junior, Marlise De Castro Ribeiro, Omar Arambula, Paulo Diniz Gama, Renata Menon, Rodrigo Thomaz, Rogério Morales, Sidney Gomes, Silvana Sobreira, Soniza Alves-Leon, Suzana Machado, Taysa Alexandrino Ribeiro, Valeria Pereira, Vanessa Costa, Marilia Perin, Adaucto Nóbrega Junior, Yara Fragoso, Eduardo Donadi, tarso Adoni, Maria Lúcia Ferreira, Dagoberto Callegaro, Maria Fernanda Mendes, Doralina Brum, Felipe Von Glehn

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    • LB1248 - Proof-of-concept trial of a novel dietary supplement, Multicafe®, for fatigue in multiple sclerosis (View Presentation)

      Keyword: Symptom Management

      Giordani Dos Passos, Augusto Bressanim, Aline de Cássia Dos Santos, Cristiane Trevisan, Georgia Tavares, Lucas Gonçalves, Luiz Eduardo Canton, Marina Olmi, Matheus Urbanetto, Cibele Teixeira, Verônica Azzolin, Ivana Da Cruz, Douglas Sato

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    • LB1249 - Types of pharmaceutical intervention in patients with Multiple sclerosis (MS): A fine line between immunosuppressive and risk of COVID-19 infection (View Presentation)

      Keyword: COVID-19

      Maryam Sadeghi, Anali Kanani, Ehsan Barouti, Seyed Massood Nabavi

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    • LB1250 - Neuronal integrity is associated to peripheral leukocyte dysfunction in asymptomatic Multiple Sclerosis (MS) first-degree relatives (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Hanane Touil, Tina Roostaei, Charles White, Zongqi Xia, Phillip De Jager

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    • LB1251 - National Multiple Sclerosis Society Healthcare Provider Councils COVID-19 Survey (View Presentation)

      Keyword: COVID-19

      Elizabeth Morrison, Carrie Hersh

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    • LB1252 - COVID-19 and multiple sclerosis – prevalence and the impact of disease modifying therapies (View Presentation)

      Keyword: Disease Modifying Therapies – Risk Management

      Bernd Kieseier, Rajani Rajbhandari, Arman Altincatal, Michelle Kim, Aaron Berdofe, Maha Radhakrishnan, Eunice Jung, Al Sandrock, Carl De Moor

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    • LB1253 - The Impact Of COVID19 Pandemic On NeuromyelitisOptica Spectrum Disorder Patients In Isfahan , Iran. (View Presentation)

      Keyword: COVID-19

      roshanak Mehdipour, Fereshte Ashtari

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    • LB1254 - A real-world data study of Coronavirus-2019 disease severity in patients with multiple sclerosis treated with ocrelizumab (View Presentation)

      Keyword: COVID-19

      Kiran Tailor, Paul Dillon, Ali Waqar, Spyros Roumpanis, Michael Martinec, Erwan Muros-Le Rouzic

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    • LB1255 - Influence of social isolation measures due to Covid-19 on the quality of life of people with Multiple Sclerosis (View Presentation)

      Keyword: COVID-19

      Alice Dias, Juliana Telles, Mauricio Bando

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    • LB1256 - New findings from the 2020 MS Barometer on MS prevalence, practicing neurologists and use of disease-modifying drugs across Europe (View Presentation)

      Keyword: Epidemiology

      Catherine Whicher, Nora Kriauzaite, Tom Albone, Elisabeth Kasilingam, Adam Taylor, Daniel Ratchford, Christine Merkel

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    • LB1257 - Nowcasting Covid-19 in patients with Multiple Sclerosis via social media (View Presentation)

      Keyword: COVID-19

      Andreas Hoepner, Alexander Arimond, Andrew Chan, Anke Salmen, Michael Graber, Robert Hoepner

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    • LB1258 - SARS-CoV-2 pandemic lockdown: perceived consequences on multiple sclerosis patients (View Presentation)

      Keyword: COVID-19

      Arianna Sartori, Alessandro Dinoto, Fulvio Pasquin, Alessio Bratina, Antonio Bosco, Paolo Manganotti

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    • LB1259 - Recurrent CNS Demyelination in a Pediatric Patient with History of Guillain-Barre Syndrome variant Being Treated with IVIG (View Presentation)

      Keyword: Pediatric MS

      Brittney Rhem, Cynthia Wang, Diana Castro

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    • LB1260 - Optic neuritis in long standing clinically stable secondary progressive multiple sclerosis after SARS-CoV-2 infection: a mere coincidence? (View Presentation)

      Keyword: COVID-19

      Arianna Sartori, Alessandro Dinoto, Fulvio Pasquin, Alessio Bratina, Antonio Bosco, Paolo Manganotti

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    • LB1261 - Resting-state neural activity, cognitive functioning and reserve in relapsing-remitting multiple sclerosis: a microstates EEG study. (View Presentation)

      Keyword: Neuropsychology and Cognition

      Sara Baldini, Maria Elisa Morelli, Arianna Sartori, Alessandro Dinoto, Alessio Bratina, Antonio Bosco, Paolo Manganotti

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    • LB1262 - Low Prevalence of SARS-CoV-2 Antibodies in People with Multiple Sclerosis Residing in Massachusetts (View Presentation)

      Keyword: COVID-19

      Eric Klawiter, Jade Smith, Kristina Brewer, Kirsten Stockel, Stephanie Fischinger, Corinne Luedemann, Heidi Bien, Andrew Russo, Anna Vaeth, Rohit Bakshi, Shamik Bhattacharyya, Ann Cabot, Ilena George, Rebecca Gillani, Meghan Hickey, Maria Houtchens, Tamara Bockow Kaplan, Dorlan Kimbrough, Ilya Kister, Farrah Mateen, Marcelo Matiello, Christopher Severson, Tarun Singhal, James Stankiewicz, Lynn Stazzone, Howard Weiner, Jonathan Zurawski, Ani Eloyan, Tanuja Chitnis, Galit Alter

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    • LB1263 - Introduction of CSF immunoglobulin κ light chains testing as a complement to oligoclonal bands evaluation (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      George Medvedev, Arun Garg, Karina Rodriguez Capote, Alison Fong

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    • LB1264 - Endocrine disrupting chemicals affect T cell phenotypes and show a role for environmental factors in MS pathophysiology. (View Presentation)

      Keyword: Gender Differences, Hormones and Sex Chromosomes

      Maria Popescu, Talia Feldman, Hrishikesh Lokhande, Shrishti Saxena, Fermisk Saleh, Patricia Gaitan-Walsh, Paola Castro-Mendoza, Tanuja Chitnis

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    • LB1265 - "TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of CNS demyelination." (View Presentation)

      Keyword: Neuroprotection, Regeneration and/or Remyelination

      Fabia Filipello, Francesca Cignarella, Bryan Bollman, Claudia Cantoni, Alberto Locca, Robert Mikesell, Bruno Bruno A. Benitez, Carlos Cruchaga, Danilo Licastro, Oscar Harari, Arnon Rosenthal, Tina Schwabe, Ilaria Tassi, Laura Piccio

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    • LB1266 - Descriptive data analysis of covid-19 among patients with multiple  sclerosis; A cross-sectional study of southern Iran (View Presentation)

      Keyword: COVID-19

      Maryam Poursadeghfard, Mahnaz Bayat, Afshin Borhani Haghighi, Hossein Molavi Vardanjani, Alireza Fayyazpoor, Daniyal Salehi

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    • LB1267 - Teriflunomide Enhanced Innate and Adaptive Immune Regulatory Function in Treating Multiple Sclerosis (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Qi Wu, Qin Wang, Jennifer Yang, Aiya Saad, ahya Ali, Catherine Dowling, Caitlyn Fisher, Yang Mao-Draayer

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    • LB1268 - No evidence for SARS-CoV-2 transcripts and disease exacerbation in COVID-19 multiple sclerosis brain (View Presentation)

      Keyword: COVID-19

      Vidmante Fuchs, Michael Kutza, Sven Wischnewski, Nikolaus Deigendesch, Luc Lutz, Laila Kulsvehagen, Gerda Ricken, Ludwig Kappos, Alexandar Tzankov, Simon Hametner, Stephan Frank, Lucas Schirmer, Anne-Katrin Pröbstel

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    • LB1269 - Higher parietal and premotor cortex activation and connectivity during treadmill walking in Persons with Multiple Sclerosis versus healthy controls (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Soha Saleh, Michael Glassen, Armand Hoxha, Guang Yue, John Deluca

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    • LB1270 - DICAM : A new cell adhesion molecule involved in myeloid cells infiltration in Multiple Sclerosis (View Presentation)

      Keyword: Pathogenesis – the Blood-Brain Barrier

      Camille Grasmuck, Soufiane Ghannam, Stephanie Zandee, Rose-Marie Rébillard, Chloé Hoornaert, Marc Charabati, Evelyn Peelen, Lyne Bourbonniere, Sandra Larouche, Camille Pittet, Alexandre Prat

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    • LB1271 - MRI insights into myelin damage in Susac Syndrome (View Presentation)

      Keyword: Imaging

      Poljanka Johnson, Jillian Chan, Irene Vavasour, Shawna Abel, Lisa Eunyoung Lee, Heather Yong, Vanessa Wiggermann, Cornelia Laule, Andrew Woolfenden, Anthony Traboulsee, David Li, Roger Tam, Shannon Kolind, Robert Carruthers

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    • LB1272 - Distinct co-varying functional-structural patterns in multiple sclerosis for physical disability and cognitive impairment (View Presentation)

      Keyword: Imaging

      Antonio Giorgio, Jian Zhang, Claudia Vinciguerra, Maria Laura Stromillo, Marzia Mortilla, Riccardo Tappa Brocci, Marco Battaglini, Emilio Portaccio, Maria Pia Amato, Nicola De Stefano

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    • LB1273 - Telehealth Utilization in Four MS Centers During the COVID Pandemic: Real-world evidence from the MS-CQI improvement research collaborative. (View Presentation)

      Keyword: COVID-19

      BRANT Oliver, Karen Walsh, FALGUNI Mehta, Sarah England

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    • LB1274 - Modeling subject-level disease progression for Multiple Sclerosis in clinical trials using machine learning (View Presentation)

      Keyword: Machine Learning/Network Science

      Dana Jasek, Jonathan Walsh

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    • LB1275 - Enriching neuroimmunology telemedicine encounters with objective measures of vision during the SARS-CoV-2 pandemic (View Presentation)

      Keyword: COVID-19

      Hadas Stiebel-Kalish, Yakov Rabinovich, Alon Tiosano, Omer Bialer

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    • LB1276 - Contribution of antibodies against coagulation components in the circuit of coagulation-immune system: Potential biomarkers of Multiple Sclerosis? (View Presentation)

      Keyword: Biomarkers and Bioinformatics

      Maria S. Hadjiagapiou, George Krashias, Christina Christodoulou, Marios Pantzaris, Anastasia Lambrianides

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    • LB1277 - Evaluation of intermittent fasting diet in multiple sclerosis (View Presentation)

      Keyword: Clinical Trials

      Kar Lun Alan Lau, George Medvedev

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    • LB1278 - Teriflunomide: An Immune Modulating Drug with Antiviral Properties (View Presentation)

      Keyword: Disease Modifying Therapies – Mechanism of Action

      Francesca Gilli, Michael Linzey, Nora Welsh, Jeffrey Chavin, Krista Disano, Andrew Pachner

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    • LB1279 - Initial Symptom at Onset in newly diagnosed Hispanic MS patients between 2017-2019: An Update (View Presentation)

      Keyword: Epidemiology

      Athena Dao, Ramon Vega, Cristina Rubi, Viviana Martinez, Astrid Diaz Quiñones, Frances Casillas, Angel Lopez, Ivonne Vicente, Angel Chinea Martinez

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    • LB1281 - Experience of a northeast Brazilian demyelinating disorders center in remote screening of COVID-19 during the sars-cov-2 pandemic. (View Presentation)

      Keyword: COVID-19

      Igor Santiago, Milena Pitombeira, Lucas Mendes, Ivna Pereira Nobrega, Iury Hélder Dantas, Keyla Rejana De Morais, Patrícia D´almeida, Carla Da Silva, Paulo Sérgio Lisboa, Maria Luisa De Melo, Melyssa Gonçalves, Gabriela Martins, José Artur Costa D'Almeida

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    • LB1282 - Machine learning of deep grey matter volumes on MRI for predicting new disease activity after a first clinical demyelinating event (View Presentation)

      Keyword: Machine Learning/Network Science

      Maryam Tayyab, Luanne Metz, Adam Dvorak, Shannon Kolind, Shelly Au, Robert Carruthers, Anthony Traboulsee, Roger Tam

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